Article ; Online: Russell Viper Venom: A Journey from the Bedside to the Bench and Back to the Bedside.
Seminars in thrombosis and hemostasis
2023 Volume 50, Issue 1, Page(s) 115–118
Abstract: Russell Viper Venom (RVV) is widely used as a diagnostic test for antiphospholipid syndrome (APS). But the history of how this venom came to be discovered is well known. Dr Patrick Russell is responsible for the identification of the venom during his ... ...
Abstract | Russell Viper Venom (RVV) is widely used as a diagnostic test for antiphospholipid syndrome (APS). But the history of how this venom came to be discovered is well known. Dr Patrick Russell is responsible for the identification of the venom during his work on snake bites in India while Dr Robert Macfarlane used it to staunch bleeding in persons with haemophilia. The ability to directly activate factor X led RVV to the laboratory diagnosis of APS. More recently, it has come back to clinical world with a potential for an engineered factor X activator from RVV to be used in the treatment of haemophilia. |
---|---|
MeSH term(s) | Humans ; Viper Venoms ; Hemophilia A ; Snake Bites/therapy ; India |
Chemical Substances | Viper Venoms |
Language | English |
Publishing date | 2023-07-28 |
Publishing country | United States |
Document type | Journal Article |
ZDB-ID | 196901-8 |
ISSN | 1098-9064 ; 0094-6176 |
ISSN (online) | 1098-9064 |
ISSN | 0094-6176 |
DOI | 10.1055/s-0043-1771269 |
Database | MEDical Literature Analysis and Retrieval System OnLINE |
More links
Kategorien
In stock of ZB MED Cologne/Königswinter
Zs.A 1259: Show issues | Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (1.OG) ab Jg. 2022: Lesesaal (EG) |
Order via subito
This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.