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  1. Book ; Online ; E-Book: Molecular biology

    Zlatanova, J. / Van Holde, K. E.

    structure and dynamics of genomes and proteomes

    2023  

    Abstract: Molecular Biology: Structure and Dynamics of Genomes and Proteomes second edition illustrates the essential principles behind the transmission and expression of genetic information at the level of DNA, RNA, and proteins. Emphasis is on the experimental ... ...

    Author's details Jordanka Zlatanova, Kensal E. van Holde
    Abstract Molecular Biology: Structure and Dynamics of Genomes and Proteomes second edition illustrates the essential principles behind the transmission and expression of genetic information at the level of DNA, RNA, and proteins. Emphasis is on the experimental basis of discovery and the most recent advances in the field while presenting a rigorous, yet still concise, summary of the structural mechanisms of molecular biology. Topics new to this edition include the CRISPR-Cas gene editing system, Coronaviruses - structure, genome, vaccine and drug development, and newly recognized mechanisms for transcription termination. The text is written for advanced undergraduate or graduate-level courses in molecular biology.Key Features-Highlights the experimental basis of important discoveries in molecular biology. Thoroughly updated with new information on gene editing tools, viruses, and transcription mechanisms, termination and antisense. Provides learning objectives for each chapter. Includes a list of relevant videos from the Internet about the topics covered in the chapter.
    Keywords Genomes ; Molecular biology ; Proteomics
    Subject code 572.86
    Language English
    Size 1 online resource (732 pages)
    Edition Second edition.
    Publisher CRC Press
    Publishing place Boca Raton ; Abingdon, Oxon
    Document type Book ; Online ; E-Book
    Note Includes index.
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    ISBN 1-00-313292-8 ; 1-003-13292-8 ; 1-000-82298-2 ; 1-000-82292-3 ; 9780367674083 ; 978-1-00-313292-9 ; 978-1-003-13292-9 ; 978-1-000-82298-4 ; 978-1-000-82292-2 ; 0367674084
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Book ; Online ; E-Book: The evolution of molecular biology

    Van Holde, K. E. / Zlatanova, Jordanka

    the search for the secrets of life

    2018  

    Abstract: The Evolution of Molecular Biology: The Search for the Secrets of Life provides the historical knowledge behind techniques founded in molecular biology, also presenting an appreciation of how, and by whom, these discoveries were made. It deals with the ... ...

    Author's details Kensal E. van Holde, Jordanka Zlatanova
    Abstract "The Evolution of Molecular Biology: The Search for the Secrets of Life provides the historical knowledge behind techniques founded in molecular biology, also presenting an appreciation of how, and by whom, these discoveries were made. It deals with the evolution of intellectual concepts in the context of active research in an approachable language that accommodates readers from a variety of backgrounds. Each chapter contains a prologue and epilogue to create continuity and provide a complete framework of molecular biology. This foundational work also functions as a historical and conceptual supplement to many related courses in biochemistry, biology, chemistry, genetics and history of science. In addition, the book demonstrates how the roots of discovery and advances-and an individual's own research-have grown out of the history of the field, presenting a more complete understanding and context for scientific discovery"--Back cover
    Keywords Molecular Biology / history
    Language English
    Size 1 Online-Ressource (xii, 230 Seiten), Illustrationen, Diagramme
    Publisher Elsevier AP
    Publishing place London
    Publishing country Great Britain
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT019732664
    ISBN 978-0-12-812918-0 ; 9780128129173 ; 0-12-812918-2 ; 0128129174
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  3. Book: Principles of physical biochemistry

    Van Holde, K. E. / Johnson, W. Curtis / Ho, Pui Shing

    1998  

    Author's details Kensal E. van Holde ; W. Curtis Johnson ; P. Shing Ho
    Keywords Biochemistry ; Chemistry, Physical ; Biophysikalische Chemie
    Subject Physikalische Biochemie
    Language English
    Size XII, 657 S. : Ill., graph. Darst.
    Publisher Prentice Hall
    Publishing place Upper Saddle River, NJ
    Publishing country United States
    Document type Book
    HBZ-ID HT008351679
    ISBN 0-13-720459-0 ; 978-0-13-720459-5
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    1998 A 2963 order for loan Magazin

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  4. Book: Biochemistry

    Mathews, Christopher K. / Van Holde, K. E.

    1996  

    Author's details Christopher K. Mathews ; K. E. van Holde
    Keywords Biochemistry ; Biochemie
    Subject Biologische Chemie
    Language English
    Size XXVII, 1159 S. : Ill., graph. Darst.
    Edition 2. ed.
    Publisher Benjamin/Cummings
    Publishing place Menlo Park, Calif. u.a.
    Publishing country United States
    Document type Book
    HBZ-ID HT007283388
    ISBN 0-8053-3931-0 ; 978-0-8053-3931-4
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    1997 A 544 order for loan Magazin
    2006 A 6246 order for loan Magazin

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  5. Book: Chromatin

    Van Holde, K. E.

    (Springer series in molecular biology)

    1988  

    Author's details Kensal E. van Holde
    Series title Springer series in molecular biology
    Keywords Chromatin
    Subject Nucleohistone
    Size XII, 497 S. : Ill., graph. Darst.
    Edition 1. [Dr.]
    Publisher Springer
    Publishing place New York u.a.
    Publishing country United States
    Document type Book
    HBZ-ID HT003321498
    ISBN 3-540-96694-3 ; 0-387-96694-3 ; 978-3-540-96694-4 ; 978-0-387-96694-6
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    1989 A 2688 order for loan Magazin

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  6. Book: Biochemistry

    Mathews, Christopher K. / Van Holde, K. E.

    (Benjamin/Cummings series in life sciences and chemistry)

    1990  

    Author's details Christopher K. Mathews ; K. E. van Holde
    Series title Benjamin/Cummings series in life sciences and chemistry
    Keywords Biochemistry ; Biochemie
    Subject Biologische Chemie
    Language English
    Size XXIX, 1129 S. : Ill., graph. Darst.
    Publisher Benjamin/Cummings
    Publishing place Redwood City, Calif. u.a.
    Publishing country United States
    Document type Book
    HBZ-ID HT003585013
    ISBN 0-8053-5015-2 ; 978-0-8053-5015-9
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    1991 A 704 order for loan Magazin

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  7. Book: Molecular biology

    Zlatanova, J / Van Holde, K. E

    structure and dynamics of genomes and proteomes

    2016  

    Author's details Jordanka Zlatanova, Kensal E. van Holde
    MeSH term(s) Molecular Biology/methods ; Transcription, Genetic/genetics ; Genome/physiology ; Proteome/physiology
    Language English
    Size xix, 624 pages :, illustrations
    Document type Book
    ISBN 9780815345046 ; 0815345046
    Database Catalogue of the US National Library of Medicine (NLM)

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  8. Article: Sedimentation equilibrium and the foundations of protein chemistry.

    van Holde, K E

    Biophysical chemistry

    2004  Volume 108, Issue 1-3, Page(s) 5–8

    MeSH term(s) Carboxyhemoglobin/chemistry ; Methemoglobin/chemistry ; Molecular Weight ; Protein Binding ; Proteins/chemistry ; Solutions ; Ultracentrifugation/methods ; Ultracentrifugation/trends
    Chemical Substances Proteins ; Solutions ; Methemoglobin (9008-37-1) ; Carboxyhemoglobin (9061-29-4)
    Language English
    Publishing date 2004-03-01
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 185052-0
    ISSN 1873-4200 ; 0301-4622
    ISSN (online) 1873-4200
    ISSN 0301-4622
    DOI 10.1016/j.bpc.2003.10.004
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1147: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  9. Book: Physical Biochemistry

    Van Holde, K. E.

    (Foundations of Modern Biochemistry Series)

    1971  

    Author's details Kensal Edward van Holde
    Series title Foundations of Modern Biochemistry Series
    Keywords Biophysikalische Chemie
    Subject Physikalische Biochemie
    Size IX, 246 S. ; 8-o
    Publisher Prentice-Hall
    Publishing place Englewood Cliffs, N.J
    Publishing country United States
    Document type Book
    HBZ-ID HT008976956
    ISBN 0-13-665885-7 ; 0-13-665877-6 ; 978-0-13-665885-6 ; 978-0-13-665877-1
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    1973 A 492 order for loan Magazin

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  10. Article: A hypothesis concerning diffusion-limited protein-ligand interactions.

    van Holde, K E

    Biophysical chemistry

    2003  Volume 101-102, Page(s) 249–254

    Abstract: A simple assumption allows the prediction of the numerical value for a 'universal' limiting kinetic rate for wholly diffusion-limited reactions between small neutral molecules and macromolecules. This prediction is compared with appropriate experimental ... ...

    Abstract A simple assumption allows the prediction of the numerical value for a 'universal' limiting kinetic rate for wholly diffusion-limited reactions between small neutral molecules and macromolecules. This prediction is compared with appropriate experimental data for binding of ligands to myoglobin and to enzymes. It is shown that in the absence of electrostatic effects, this limit is approached but not exceeded. The model also makes very specific predictions concerning the viscosity and temperature dependence of such reactions.
    MeSH term(s) Kinetics ; Ligands ; Protein Binding ; Proteins/metabolism ; Viscosity
    Chemical Substances Ligands ; Proteins
    Language English
    Publishing date 2003-01-01
    Publishing country Netherlands
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 185052-0
    ISSN 1873-4200 ; 0301-4622
    ISSN (online) 1873-4200
    ISSN 0301-4622
    DOI 10.1016/s0301-4622(02)00176-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1147: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

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