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  1. Article ; Online: Protective effects of Jing-Si-herbal-tea in inflammatory cytokines-induced cell injury on normal human lung fibroblast

    Wang, Chien-Hao / Yang, Jai-Sing / Chen, Chao-Jung / Su, San-Hua / Yu, Hsin-Yuan / Juan, Yu-Ning / Chiu, Yu-Jen / Ho, Tsung-Jung

    Tzu chi medical journal

    2024  Volume 36, Issue 2, Page(s) 152–165

    Abstract: Objectives: The protective effects and related mechanisms of Jing-Si herbal tea (JSHT) were ...

    Abstract Objectives: The protective effects and related mechanisms of Jing-Si herbal tea (JSHT) were investigated in cellular damage mediated by pro-inflammatory cytokines, including interleukin (IL)-1β, IL-6, and tumor necrosis factor-α, on normal human lung fibroblast by multiomic platform analysis.
    Materials and methods: The
    Results: In
    Conclusion: The findings from our research indicate that JSHT holds promise as a therapeutic agent, potentially offering advantageous outcomes in treating virus infections through various mechanisms. Furthermore, the primary bioactive components in JSHT justify extended research in antiviral drug development, especially in the context of addressing coronavirus.
    Language English
    Publishing date 2024-03-26
    Publishing country India
    Document type Journal Article
    ZDB-ID 2452925-4
    ISSN 2223-8956 ; 2223-8956
    ISSN (online) 2223-8956
    ISSN 2223-8956
    DOI 10.4103/tcmj.tcmj_267_23
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: [Medication regularity and potential targets of Professor XU Jing-fan's prescription for treating ulcerative colitis].

    Ning, Li-Qin / Ye, Bai / Shen, Hong / Lu, Wei-Min / Xu, Dan-Hua / Yan, Jing / Tan, Chang / Tang, De-Cai

    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica

    2018  Volume 43, Issue 5, Page(s) 1042–1048

    Abstract: ... of modern refractory diseases by WHO. Professor XU Jing-fan, a great master of traditional Chinese medicine ...

    Abstract Ulcerative colitis (UC) is a chronic nonspecific inflammation mainly involving rectum and colon mucosa, which seriously affects the health and quality of life of patients, and is listed as one of modern refractory diseases by WHO. Professor XU Jing-fan, a great master of traditional Chinese medicine, has accumulated rich experiences in the treatment of UC. The study collected Professor XU's 77 prescriptions of treating UC, analyzed the frequency of traditional Chinese medicines and there categories, and investigated the medication regularity by the system clustering method. The findings showed that the most frequently used drugs were clearing-heat herbs, which were followed by hemostatic herbs, excreting-dampness herbs, improving-digestion herbs and tonifying-Qi herbs. At the same time, the commonly combined drugs were excavated. Finally, in order to analyze potential molecular targets of the frequently used herbs, GO enrichment analysis and KEGG signal pathway enrichment analysis were performed with bioinformatics analysis tool for molecular mechanism of traditional Chinese medicine (BATMAN-TCM). The results indicated that Chinese herbal compounds may treat UC by activating PPAR-γ pathway and regulating intestinal inflammation. The exact mechanisms shall be verified through subsequent molecular biological experiments.
    MeSH term(s) Colitis, Ulcerative/drug therapy ; Drug Prescriptions ; Drugs, Chinese Herbal/pharmacology ; Humans ; Medicine, Chinese Traditional ; Quality of Life
    Chemical Substances Drugs, Chinese Herbal
    Language Chinese
    Publishing date 2018-04-16
    Publishing country China
    Document type Journal Article
    ZDB-ID 1004649-5
    ISSN 1001-5302 ; 0254-0029
    ISSN 1001-5302 ; 0254-0029
    DOI 10.19540/j.cnki.cjcmm.2018.0035
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Sperm mtDNA copy number, telomere length, and seminal spermatogenic cells in relation to ambient air pollution: Results of a cross-sectional study in Jing-Jin-Ji region of China.

    Zhou, Lixiao / Li, Lipeng / Hao, Guimin / Li, Binghua / Yang, Sujuan / Wang, Ning / Liang, Jiaming / Sun, Hongyue / Ma, Shitao / Yan, Lina / Zhao, Chunfang / Wei, Yanjing / Niu, Yujie / Zhang, Rong

    Journal of hazardous materials

    2020  Volume 406, Page(s) 124308

    Abstract: Evidences on the association of air pollutants and semen quality were limited and mechanism-based biomarkers were sparse. We enrolled 423 men at a fertility clinic in Shijiazhuang, China to evaluate associations between air pollutants and semen quality ... ...

    Abstract Evidences on the association of air pollutants and semen quality were limited and mechanism-based biomarkers were sparse. We enrolled 423 men at a fertility clinic in Shijiazhuang, China to evaluate associations between air pollutants and semen quality parameters including the conventional ones, sperm mitochondrial DNA copy number (mtDNAcn), sperm telomere length (STL) and seminal spermatogenic cells. PM
    MeSH term(s) Air Pollutants/analysis ; Air Pollutants/toxicity ; Air Pollution/adverse effects ; Air Pollution/analysis ; China ; Cross-Sectional Studies ; DNA Copy Number Variations ; DNA, Mitochondrial/pharmacology ; Humans ; Male ; Particulate Matter/analysis ; Particulate Matter/toxicity ; Semen Analysis ; Sperm Count ; Spermatozoa ; Telomere/chemistry ; Telomere/genetics
    Chemical Substances Air Pollutants ; DNA, Mitochondrial ; Particulate Matter
    Language English
    Publishing date 2020-10-23
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 1491302-1
    ISSN 1873-3336 ; 0304-3894
    ISSN (online) 1873-3336
    ISSN 0304-3894
    DOI 10.1016/j.jhazmat.2020.124308
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Separating the impacts of climate change and land surface alteration on runoff reduction in the Jing River catchment of China

    Ning, T. / Li, Z. / Liu, W.

    Catena

    2016  Volume 147, Issue -, Page(s) 80

    Language English
    Document type Article
    ZDB-ID 519608-5
    ISSN 0341-8162
    Database Current Contents Nutrition, Environment, Agriculture

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  5. Article: Separating the impacts of climate change and land surface alteration on runoff reduction in the Jing River catchment of China

    Ning, Tingting / Wenzhao Liu / Zhi Li

    Catena. 2016 Dec., v. 147

    2016  

    Abstract: ... to runoff reduction is thus very important for water resources management. Taking the Jing River catchment ...

    Abstract The Loess Plateau of China is subject to severe water shortages, and the runoff reduction observed in most watersheds exacerbates the problem. Quantifying the contributions of environmental changes to runoff reduction is thus very important for water resources management. Taking the Jing River catchment as the study area, the changes in runoff for the period of 1961–2010 at three gauge stations—the catchment outlet (Zhang Jia Shan, ZJS) and the two others from the upper reach (Yang Jia Ping, YJP, and Yu Luo Ping, YLP) were analyzed in this study. Using the Budyko framework, the spatiotemporal variations of the contributions of precipitation (P), potential evapotranspiration (ET0), and land surface conditions (represented by the parameter n in the Choudhury–Yang equation) to runoff changes were evaluated. A significant downward trend in runoff was detected for the ZJS and YJP stations. The sensitivity of the runoff changes to the different environmental factors considered was different. The sensitivity coefficient was the greatest for P, intermediate for ET0, and smallest for the land surface condition (n). However, the sensitivity coefficients are becoming greater over time. The decrease in P was the dominant factor in the runoff reduction at the three stations, but its effect was largely offset by the increase in n at YLP. The contribution of land surface alteration to runoff reduction has been increasing in recent years, which indicates that the improvement of vegetation coverage and the construction of terraces and check dams have strengthened their impacts on runoff. Therefore, careful attention should be paid to the hydrological effects of soil conservation measures on runoff.
    Keywords climate change ; environmental factors ; equations ; evapotranspiration ; rivers ; runoff ; soil conservation ; spatial variation ; temporal variation ; terraces ; vegetation ; water management ; water shortages ; watersheds ; China
    Language English
    Dates of publication 2016-12
    Size p. 80-86.
    Publishing place Elsevier B.V.
    Document type Article
    ZDB-ID 519608-5
    ISSN 1872-6887 ; 0008-7769 ; 0341-8162
    ISSN (online) 1872-6887 ; 0008-7769
    ISSN 0341-8162
    DOI 10.1016/j.catena.2016.06.041
    Database NAL-Catalogue (AGRICOLA)

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  6. Book ; Online: Magnetic Resonance Imaging for Radiation Therapy

    Wen, Ning / Cao, Yue / Cai, Jing / Cai, Jing

    2020  

    Keywords Medicine ; Oncology ; multiparametric MRI ; synthetic CT (sCT) ; deep learning ; MR Linac ; radiomics analysis
    Size 1 electronic resource (170 pages)
    Publisher Frontiers Media SA
    Document type Book ; Online
    Note English ; Open Access
    HBZ-ID HT021230616
    ISBN 9782889637621 ; 288963762X
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  7. Book ; Online: Motor System and Motor Diseases: from Molecules to Circuits

    Zhu, Jing-Ning / Shen, Ying / Mermelstein, Paul G.

    2020  

    Keywords Science: general issues ; Neurosciences ; cortex ; basal ganglia ; cerebellum ; vestibular system ; spinal cord ; motor control ; motor learning ; motor perception ; motor diseases
    Size 1 electronic resource (355 pages)
    Publisher Frontiers Media SA
    Document type Book ; Online
    Note English ; Open Access
    HBZ-ID HT021230857
    ISBN 9782889637348 ; 2889637344
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  8. Book ; Online ; E-Book: Rapid On-Site Evaluation (ROSE) in Diagnostic Interventional Pulmonology

    Feng, Jing / Ning, Wen / Jiang, Dianhua / Chen, Jingyu / Wu, Bo

    Volume 2: Interstitial Lung Diseases

    2020  

    Abstract: This book demonstrates the recent advances in rapid on-site evaluation (ROSE) for differential diagnosis of interstitial lung disease (ILD). Interstitial lung disease is a group of diffuse parenchymal lung disorders affecting the interstitium, a part of ... ...

    Author's details edited by Jing Feng, Wen Ning, Dianhua Jiang, Jingyu Chen, Bo Wu
    Abstract This book demonstrates the recent advances in rapid on-site evaluation (ROSE) for differential diagnosis of interstitial lung disease (ILD). Interstitial lung disease is a group of diffuse parenchymal lung disorders affecting the interstitium, a part of the lung's anatomic structure, causing inflammation, scarring, or excess fluid. ILDs include interstitial pneumonia, idiopathic pulmonary fibrosis, nonspecific interstitial pneumonitis, cryptogenic organizing pneumonia and sarcoidosis, which are associated with various degrees of morbidity and mortality rates. ROSE has proven its value in diagnosis with routine transbronchial lung biopsy (TBLB) procedures, especially in difficult clinical cases. The first part of the book discusses the principals of performing ROSE procedures, reviews the basic concepts and summarizes the distribution and morphology of tracheal/ bronchial/ pulmonary cells. The second part covers specific interstitial disorders, including a number of difficult and rare cases, and features iCT images and cytological illustrations. Providing readers with valuable insights, the book is an important resource for practitioners involved in the care and treatment of patients with ILD. This book is part of the 4-volume collection ROSE in Diagnostic Interventional Pulmonology.
    Keywords Respiratory organs—Diseases ; Pathology ; Radiology ; Pneumology/Respiratory System ; Imaging / Radiology
    Subject code 616.2
    Language English
    Size 1 online resource (VI, 252 p. 331 illus., 254 illus. in color.)
    Edition 1st ed. 2020.
    Publisher Springer Singapore ; Imprint: Springer
    Publishing place Singapore
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    ISBN 981-15-0939-5 ; 981-15-0938-7 ; 978-981-15-0939-1 ; 978-981-15-0938-4
    DOI 10.1007/978-981-15-0939-1
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  9. Article ; Online: Discussion on the influence of geological parameters on reservoir development in Daqing Oilfield

    Ning Jing

    E3S Web of Conferences, Vol 352, p

    2022  Volume 01059

    Abstract: With the improvement of social development level, the development speed of all walks of life has been rapidly improved. This increase in speed makes the industry’s demand for energy also show a growing trend. Based on this, relevant departments have also ...

    Abstract With the improvement of social development level, the development speed of all walks of life has been rapidly improved. This increase in speed makes the industry’s demand for energy also show a growing trend. Based on this, relevant departments have also increased the research on oilfield exploration and reservoir development. Among them, through research, it is found that geological parameters have a very significant impact on the oil reservoir development effect. Only based on geological parameters can the developed oil reservoir have the support of objective data and guarantee the development effect. This paper will analyze and study the influence of geological parameters on reservoir development in Daqing oilfield.
    Keywords daqing oilfield ; geological parameters ; reservoir development ; effects on ; Environmental sciences ; GE1-350
    Language English
    Publishing date 2022-01-01T00:00:00Z
    Publisher EDP Sciences
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  10. Article ; Online: In Silico Investigation of Palladium-Catalyzed Chemoselective Monoalkoxycarbonylation of 1,3-diynes for Conjugated Enynes Synthesis.

    Ning, Xiaoyu / Jing, Yaru / Cheng, Zuohui / Li, Jingjing

    Chemphyschem : a European journal of chemical physics and physical chemistry

    2024  Volume 25, Issue 6, Page(s) e202300620

    Abstract: The palladium-catalyzed monoalkoxycarbonylation of 1,3-diynes provides a chemoselective method for the construction of synthetically useful conjugated enynes. Here, in silico unraveling the detailed mechanism of this reaction and the origin of ... ...

    Abstract The palladium-catalyzed monoalkoxycarbonylation of 1,3-diynes provides a chemoselective method for the construction of synthetically useful conjugated enynes. Here, in silico unraveling the detailed mechanism of this reaction and the origin of chemoselectivity were conducted. It is shown that the alkoxycarbonylation reaction preferably proceeds by a NH-Pd pathway, which including three substeps: hydropalladation, CO migratory insertion and methanolysis. The effectiveness of the NH-Pd catalytic system is attributed to the alkynyl-palladium π-back-bonding interaction, C-H⋅⋅⋅π interaction in reactant moiety and d-pπ conjugation between the Pd center and alkenyl group. The hydropalladation step was identified as the rate- and chemoselectivity-determining step, and the first alkoxycarbonylation requires a much lower energy barrier in comparison with the second alkoxycarbonylation, in line with the experimental outcomes that the monoalkoxycarbonylation product was obtained in high yield. Distortion-interaction analysis indicates the more favorable monoalkoxycarbonylation (compared to double alkoxycarbonylation) is caused by steric effect.
    Language English
    Publishing date 2024-02-12
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2025223-7
    ISSN 1439-7641 ; 1439-4235
    ISSN (online) 1439-7641
    ISSN 1439-4235
    DOI 10.1002/cphc.202300620
    Database MEDical Literature Analysis and Retrieval System OnLINE

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