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  1. Article: Uncertainty in Hormone Monitoring of Transgender and Non-Binary People.

    Greene, Dina N / Goldstein, Zil / Krasowski, Matthew D

    The journal of applied laboratory medicine

    2024  

    Language English
    Publishing date 2024-03-07
    Publishing country England
    Document type Journal Article
    ISSN 2576-9456
    ISSN 2576-9456
    DOI 10.1093/jalm/jfae013
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Selecting a SARS-CoV-2/COVID Molecular Testing Method for Your Laboratory.

    Greene, Dina N

    The journal of applied laboratory medicine

    2020  Volume 5, Issue 4, Page(s) 837–840

    MeSH term(s) Betacoronavirus/isolation & purification ; COVID-19 ; COVID-19 Testing ; Clinical Laboratory Techniques/methods ; Clinical Laboratory Techniques/standards ; Coronavirus Infections/diagnosis ; Coronavirus Infections/virology ; Humans ; Pandemics ; Pneumonia, Viral/diagnosis ; Pneumonia, Viral/virology ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-07-14
    Publishing country England
    Document type Journal Article
    ISSN 2576-9456
    ISSN 2576-9456
    DOI 10.1093/jalm/jfaa076
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Where Are the Preanalytical Stability Standards?

    Fantz, Corinne R / Greene, Dina N

    The journal of applied laboratory medicine

    2021  Volume 2, Issue 6, Page(s) 830–832

    Language English
    Publishing date 2021-01-26
    Publishing country England
    Document type Journal Article
    ISSN 2576-9456
    ISSN 2576-9456
    DOI 10.1373/jalm.2018.026062
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Persistent Hypercalcemia Despite Multiple Exploratory Neck Surgeries.

    Cheeney, Gregory / Greene, Dina N

    The journal of applied laboratory medicine

    2021  Volume 2, Issue 1, Page(s) 107–112

    Language English
    Publishing date 2021-01-26
    Publishing country England
    Document type Journal Article
    ISSN 2576-9456
    ISSN 2576-9456
    DOI 10.1373/jalm.2016.022483
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Falsely elevated serum testosterone measurements resulting from testosterone topical gel contamination of the venipuncture site: Case Series and retrospective review.

    Pichilingue, Aranza Pinedo / Greene, Dina N / Krasowski, Matthew D

    Heliyon

    2023  Volume 9, Issue 12, Page(s) e22819

    Abstract: Testosterone as replacement therapy for male hypogonadism or as gender-affirming hormone therapy for transgender and non-binary patients has increased worldwide. Commonly used formulations of testosterone include intramuscular, transdermal patch, and ... ...

    Abstract Testosterone as replacement therapy for male hypogonadism or as gender-affirming hormone therapy for transgender and non-binary patients has increased worldwide. Commonly used formulations of testosterone include intramuscular, transdermal patch, and topical gel, each of which has differing pharmacokinetics and practical challenges. In monitoring testosterone serum concentrations, contamination of the phlebotomy site by testosterone topical gel can lead to supraphysiologic (>1000 ng/dL or 34.7 nmol/L) serum concentrations of testosterone, as demonstrated in a few published case reports. The frequency of this issue is currently not known. The present study involves a retrospective search over a 13-year period across all clinical sites at an academic medical center. Out of 578 unique patients using testosterone topical gel, a total of 48 patients had at least 1 testosterone serum concentration exceed 1000 ng/dL. Documentation in the electronic health record revealed 7 patients where contamination of the phlebotomy site by topical gel was strongly supported as the cause of supraphysiologic testosterone serum concentrations. These included 5 males with primary hypogonadism, 1 male with panhypopituitarism, and a non-binary patient with gender dysphoria. The high testosterone concentrations prompted further work-up, including retesting and endocrinology consultation. There were additional cases of high testosterone serum concentration that may have been falsely elevated due to gel contamination but without sufficient supporting evidence available in the health record. Overall, we present 7 cases of spuriously high testosterone concentrations strongly suspected to be due to venipuncture performed near or at the location of prior testosterone gel application. Gel contamination should be considered as a possible cause of otherwise unexplained high testosterone serum concentration in patients receiving topical testosterone gel formulations. Patient counseling and provider awareness of this potential cause of spuriously high testosterone serum concentrations is important.
    Language English
    Publishing date 2023-11-24
    Publishing country England
    Document type Journal Article
    ZDB-ID 2835763-2
    ISSN 2405-8440
    ISSN 2405-8440
    DOI 10.1016/j.heliyon.2023.e22819
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Julia

    Greene, Dina N

    Clinical chemistry

    2017  Volume 63, Issue 8, Page(s) 1425

    Language English
    Publishing date 2017-07-27
    Publishing country England
    Document type Journal Article
    ZDB-ID 80102-1
    ISSN 1530-8561 ; 0009-9147
    ISSN (online) 1530-8561
    ISSN 0009-9147
    DOI 10.1373/clinchem.2017.271981
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Selecting a SARS-CoV-2/COVID Molecular Testing Method for Your Laboratory

    Greene, Dina N

    The Journal of Applied Laboratory Medicine

    2020  Volume 5, Issue 4, Page(s) 837–840

    Keywords covid19
    Language English
    Publisher Oxford University Press (OUP)
    Publishing country uk
    Document type Article ; Online
    ISSN 2576-9456
    DOI 10.1093/jalm/jfaa076
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article: Global Partnerships Ensure Quality Clinical Laboratory Operations.

    Peck Palmer, Octavia M / Greene, Dina N

    The journal of applied laboratory medicine

    2022  Volume 7, Issue 2, Page(s) 406–408

    MeSH term(s) Clinical Laboratory Services ; Humans ; Laboratories, Clinical
    Language English
    Publishing date 2022-01-21
    Publishing country England
    Document type Editorial ; Comment
    ISSN 2576-9456
    ISSN 2576-9456
    DOI 10.1093/jalm/jfab178
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Biotin Interference in Clinical Immunoassays.

    Colon, Paula Jenkins / Greene, Dina N

    The journal of applied laboratory medicine

    2021  Volume 2, Issue 6, Page(s) 941–951

    Abstract: Background: Shifts in consumer behavior and clinical practice have increased reports of biotin interference in immunoassays that incorporate biotin-streptavidin linkages in their design. This rise has significant implications because immunoassays are ... ...

    Abstract Background: Shifts in consumer behavior and clinical practice have increased reports of biotin interference in immunoassays that incorporate biotin-streptavidin linkages in their design. This rise has significant implications because immunoassays are used to measure a wide range of analytes across medical specialties. The objective of this article was to review the mechanisms of biotin interference, define the scope of affected immunoassays, and summarize strategies for identifying and minimizing biotin interference in clinical samples.
    Content: The literature was reviewed for reports of biotin interference and sorted by manufacturer. Abstracts from recent scientific meetings and manufacturer-provided data were also reviewed.
    Summary: Immunoassays across a range of different manufacturer platforms are subject to interference by exogenous biotin supplementation. Providers and laboratorians must be aware of this potential interference to avoid patient harm.
    Language English
    Publishing date 2021-01-26
    Publishing country England
    Document type Journal Article
    ISSN 2576-9456
    ISSN 2576-9456
    DOI 10.1373/jalm.2017.024257
    Database MEDical Literature Analysis and Retrieval System OnLINE

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