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Book ; Online ; E-Book: Medical statistics at a glance

Petrie, Aviva / Sabin, Caroline

2019

Author's details	Aviva Petrie, Caroline Sabin
Language	English
Size	1 Online-Ressource (187 Seiten), Illustrationen
Edition	4th edition
Publisher	Wiley Blackwell
Publishing place	Hoboken, NJ
Publishing country	United States
Document type	Book ; Online ; E-Book
Note	Description based on publisher supplied metadata and other sources
Remark	Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
HBZ-ID	HT020329369
ISBN	978-1-119-16782-2 ; 9781119167815 ; 1-119-16782-5 ; 1119167817
Database	ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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Article ; Online: Defining multimorbidity in people with HIV - what matters most?

Sukumaran, Luxsena / Sabin, Caroline A

Current opinion in HIV and AIDS

2023 Volume 18, Issue 2, Page(s) 59–67

Abstract: Purpose of review: Although multimorbidity (defined as the coexistence of multiple conditions) presents significant health challenges to people with HIV, there is currently no consensus on how it should be defined among this population. This review ... ...

Abstract	Purpose of review: Although multimorbidity (defined as the coexistence of multiple conditions) presents significant health challenges to people with HIV, there is currently no consensus on how it should be defined among this population. This review aimed to examine the definition of multimorbidity in existing studies among people with HIV ( n = 22). Recent findings: Variation in the definition of multimorbidity (in terms of the number and nature of conditions included) across studies among people with HIV was observed, with less than half (45%) reporting a selection criteria for conditions. The number of conditions considered ranged from 4 to 65. Certain conditions (e.g. stroke, myocardial infarction and chronic kidney disease) and risk factors (e.g. hypertension) were more frequently included, while other symptoms (e.g. joint pain, peripheral neuropathy and sleeping problems) and mental health conditions (e.g. anxiety and panic attacks) were rarely included in the definition of multimorbidity. Summary: The definition of multimorbidity among people with HIV is highly variable, with certain conditions overlooked. We propose recommendations that researchers should consider when defining multimorbidity among this population to not only enable comparisons between studies/settings but also to ensure studies consider a person-centred approach that can accurately capture multimorbidity among people with HIV.
MeSH term(s)	Humans ; Multimorbidity ; HIV Infections/complications ; HIV Infections/epidemiology ; Risk Factors ; Hypertension/epidemiology
Language	English
Publishing date	2023-01-19
Publishing country	United States
Document type	Review ; Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2502511-9
ISSN	1746-6318 ; 1746-630X
ISSN (online)	1746-6318
ISSN	1746-630X
DOI	10.1097/COH.0000000000000778
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Zs.A 6812: Show issues

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Article ; Online: Special issue on Women and HIV to mark International Women's Day.

Gilleece, Yvonne / Sabin, Caroline A

HIV medicine

2022 Volume 23, Issue 4, Page(s) 309

MeSH term(s)	Female ; HIV Infections ; Humans ; Socioeconomic Factors ; United Nations ; Women's Health
Language	English
Publishing date	2022-03-06
Publishing country	England
Document type	Editorial
ZDB-ID	2001932-4
ISSN	1468-1293 ; 1464-2662
ISSN (online)	1468-1293
ISSN	1464-2662
DOI	10.1111/hiv.13264
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Zs.A 5441: Show issues

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Article ; Online: Exploring the concept of unmet need within sexual and reproductive health in England: A qualitative Delphi exercise.

Solomon, Danielle / Gibbs, Jo / Burns, Fiona / Sabin, Caroline A

Sexual & reproductive healthcare : official journal of the Swedish Association of Midwives

2024 Volume 40, Page(s) 100969

Abstract: Background: Unmet need within sexual and reproductive health (SRH) is a concept that is difficult to define and measure. This qualitative Delphi exercise was used to ascertain the opinions of SRH professionals on the conceptualisation and measurement of ...

Abstract	Background: Unmet need within sexual and reproductive health (SRH) is a concept that is difficult to define and measure. This qualitative Delphi exercise was used to ascertain the opinions of SRH professionals on the conceptualisation and measurement of unmet need within SRH. Methods: This exercise was carried out in two rounds. In the first round, respondents responded narratively to three prompts, which were then used to create a series of statements. In the second round, participants responded narratively to the statements created in the first round. Responses from both rounds were then coded and analysed thematically. Results: Participants felt that an understanding of unmet need is an important part of SRH service design and provision, and believed that certain populations are often underrepresented within the datasets that are used to assess unmet need. Many respondents felt that a full understanding of unmet need within SRH would only come from involvement of relevant stakeholders in the process of investigating unmet need, and that qualitative methods may also have a role to play in gaining a more holistic understanding of unmet need within SRH. Conclusions: Respondents within this study felt that unmet need is complex concept that has a significant impact on service delivery and the outcomes and experiences of the most vulnerable populations. We need to improve our understanding of unmet need and prioritise stakeholder voices if we want to create interventions that address unmet need within SRH.
Language	English
Publishing date	2024-04-04
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	2541869-5
ISSN	1877-5764 ; 1877-5756
ISSN (online)	1877-5764
ISSN	1877-5756
DOI	10.1016/j.srhc.2024.100969
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Understanding the conditions included in data-driven patterns of multimorbidity: a scoping review.

Sukumaran, Luxsena / Winston, Alan / Sabin, Caroline A

European journal of public health

2023 Volume 34, Issue 1, Page(s) 35–43

Abstract: Background: Despite the growing utilization of data-driven methods to investigate multimorbidity patterns, there is currently no consensus or guidance on the conditions to include when identifying patterns. This scoping review aims to systematically ... ...

Abstract	Background: Despite the growing utilization of data-driven methods to investigate multimorbidity patterns, there is currently no consensus or guidance on the conditions to include when identifying patterns. This scoping review aims to systematically examine the nature of conditions included in existing studies using data-driven techniques. Methods: A comprehensive search of three electronic databases (MEDLINE, Web of Science and Scopus) was conducted to identify relevant publications from inception to 28 February 2022 using predefined search terms and inclusion/exclusion criteria. The reference lists and citations of relevant papers were also searched. Results: Among 7326 search results, 5444 relevant articles were identified. After screening against the eligibility criteria, 60 articles were included in the review. Half of the reviewed studies reported selection criteria for conditions, with prevalence in the population of interest being the most common criterion (40%). Most studies included at least one neurological [59 (98.3%)], musculoskeletal [58 (96.7%)], respiratory [57 (95.0%)] or mental health [56 (93.3%)] condition. In contrast, only a small proportion of studies included skin [17 (28.3%)], infections [14 (23.3%)] or autoimmune conditions [10 (16.7%)]. Nine conditions (hypertension, diabetes, cancer, arthritis, COPD, asthma, depression, stroke and osteoporosis) were included by more than half of the studies. Conclusions: This review highlights the considerable heterogeneity among the conditions included in analyses of multimorbidity patterns. Researchers should provide a clear rationale for the selection of conditions to facilitate comparisons across studies and ensure reproducibility, as well as consider selecting a diverse range of conditions to capture the complexity of multimorbidity.
MeSH term(s)	Humans ; Multimorbidity ; Reproducibility of Results ; Stroke ; Diabetes Mellitus ; Hypertension
Language	English
Publishing date	2023-10-13
Publishing country	England
Document type	Review ; Journal Article
ZDB-ID	1129243-x
ISSN	1464-360X ; 1101-1262
ISSN (online)	1464-360X
ISSN	1101-1262
DOI	10.1093/eurpub/ckad179
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Zs.A 3499: Show issues

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Book: Medical statistics at a glance

Petrie, Aviva / Sabin, Caroline

2009

Author's details	Aviva Petrie ; Caroline Sabin
Keywords	Statistics as Topic ; Research Design ; Medical statistics
Language	English
Size	180 S. : Ill., graph. Darst.
Edition	3. ed.
Publisher	Wiley-Blackwell
Publishing place	Chichester
Publishing country	Great Britain
Document type	Book
HBZ-ID	HT016007370
ISBN	978-1-4051-8051-1 ; 1-4051-8051-X
Database	Catalogue ZB MED Medicine, Health

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Shelf mark	Loan status	Location
2009 A 3464	order for loan	Magazin

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Article ; Online: Inequalities in sexual and reproductive outcomes among women aged 16-24 in England (2012-2019).

Solomon, Danielle / Gibbs, Jo / Burns, Fiona / Mohammed, Hamish / Migchelsen, Stephanie J / Sabin, Caroline A

Journal of epidemiology and community health

2024

Abstract: Background: Women aged 16-24 in England have a high burden of sexual and reproductive morbidity, with particularly poor outcomes among people living in more deprived areas (including racially minoritised populations). This analysis used national data to ...

Abstract	Background: Women aged 16-24 in England have a high burden of sexual and reproductive morbidity, with particularly poor outcomes among people living in more deprived areas (including racially minoritised populations). This analysis used national data to examine the disparities within sexual and reproductive outcomes among this population and to assess whether the patterns of inequality were consistent across all outcomes. Methods: Within this ecological study, univariable and multivariable Poisson regression analyses of neighbourhood-level data from national data sets were carried out to investigate the relationships of deprivation and ethnicity with each of six dependent variables: gonorrhoea and chlamydia testing rates, gonorrhoea and chlamydia test positivity rates, and abortion and repeat abortion rates. Results: When comparing Index of Multiple Deprivation (IMD) decile 1 (most deprived) and IMD decile 10 (least deprived), chlamydia (RR 0.65) and gonorrhoea (0.79) testing rates, chlamydia (0.70) and gonorrhoea (0.34) positivity rates, abortion rates (0.45) and repeat abortion rates (0.72) were consistently lower in IMD decile 10 (least deprived). Similarly, chlamydia (RR 1.24) and gonorrhoea positivity rates (1.92) and repeat abortion rates (1.31) were higher among black women than white women. Results were similar when both ethnicity and deprivation were incorporated into multivariable analyses. Conclusion: We found similar patterns of outcome inequality across a range of sexual and reproductive outcomes, despite multiple differences in the drivers of each outcome. Our analysis suggests that there are broad structural causes of inequality across sexual and reproductive health that particularly impact the health of deprived and black populations.
Language	English
Publishing date	2024-04-12
Publishing country	England
Document type	Journal Article
ZDB-ID	391868-3
ISSN	1470-2738 ; 0142-467X ; 0141-7681 ; 0143-005X
ISSN (online)	1470-2738
ISSN	0142-467X ; 0141-7681 ; 0143-005X
DOI	10.1136/jech-2023-220835
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Zs.A 186: Show issues

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Article ; Online: Identifying missed opportunities for hepatitis C virus antenatal testing and diagnosis in England.

Hibbert, Matthew / Simmons, Ruth / Sabin, Caroline A / Mandal, Sema / Desai, Monica

Journal of viral hepatitis

2024 Volume 31, Issue 3, Page(s) 131–136

Abstract: New case-finding opportunities are needed to achieve hepatitis C virus (HCV) elimination in England by the year 2030. HCV antenatal testing is not offered universally in England but is recommended for women with risk factors for HCV (e.g. injecting drug ... ...

Abstract	New case-finding opportunities are needed to achieve hepatitis C virus (HCV) elimination in England by the year 2030. HCV antenatal testing is not offered universally in England but is recommended for women with risk factors for HCV (e.g. injecting drug use, being born in a high-prevalence country). The aim of this analysis was to investigate the missed opportunities for HCV antenatal testing among women who had given birth and were subsequently diagnosed with HCV at some time after childbirth. By linking data on live births (2010-2020) to laboratory reports of HCV diagnoses (1995-2021), we identified all women who were diagnosed with HCV after the date of their first childbirth. This group was considered to potentially have experienced a missed opportunity for HCV antenatal testing; HCV-RNA testing and treatment outcomes were also obtained for these women. Of the 32,295 women who gave birth between 2010 and 2020 with a linked diagnosis of HCV (median age: 34 years, 72.1% UK-born), over half (n = 17,123) were diagnosed after childbirth. In multivariable analyses, the odds of being diagnosed with HCV after childbirth were higher in those of Asian Bangladeshi, Black African or Chinese ethnicity and among those born in Africa. Over four-fifths (3510/4260) of those eligible for treatment were linked to treatment, 30.7% (747/2435) of whom had a liver scarring level of at least moderate and 9.4% (228/2435) had cirrhosis. Given the potential opportunity to identify cases of HCV with targeted case-finding through antenatal services, universal opt-out testing should be considered in these settings.
MeSH term(s)	Humans ; Female ; Pregnancy ; Adult ; Hepacivirus/genetics ; Hepatitis C/diagnosis ; Hepatitis C/epidemiology ; Hepatitis C/drug therapy ; Risk Factors ; England/epidemiology ; Liver Cirrhosis ; Prevalence
Language	English
Publishing date	2024-01-04
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	1212497-7
ISSN	1365-2893 ; 1352-0504
ISSN (online)	1365-2893
ISSN	1352-0504
DOI	10.1111/jvh.13906
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Zs.A 4119: Show issues

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Article ; Online: A new year, and big changes for HIV Medicine.

Sabin, Caroline

HIV medicine

2021 Volume 23, Issue 1, Page(s) 3

MeSH term(s)	HIV Infections/drug therapy ; Humans
Language	English
Publishing date	2021-12-27
Publishing country	England
Document type	Editorial
ZDB-ID	2001932-4
ISSN	1468-1293 ; 1464-2662
ISSN (online)	1468-1293
ISSN	1464-2662
DOI	10.1111/hiv.13217
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Zs.A 5441: Show issues

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Article ; Online: The global burden of cognitive impairment in people with HIV.

Keng, Lea D / Winston, Alan / Sabin, Caroline A

AIDS (London, England)

2022 Volume 37, Issue 1, Page(s) 61–70

Abstract: Objective: While life expectancies of people with HIV (PWH) have increased through the successes of antiretroviral treatment, cognitive impairment remains a pressing concern. Prevalence estimates vary worldwide as different definitions for cognitive ... ...

Abstract	Objective: While life expectancies of people with HIV (PWH) have increased through the successes of antiretroviral treatment, cognitive impairment remains a pressing concern. Prevalence estimates vary worldwide as different definitions for cognitive impairment are used and resource availability differs across geographical settings. We aim to explore this heterogeneity and estimate the global cognitive impairment burden in PWH. Design: Systematic literature review and meta-analysis. Methods: We searched PubMed, Embase, SCOPUS, and Web of Science for studies reporting on cognitive impairment prevalence in PWH. Nine factors were investigated for their potential association with the prevalence using a univariate meta-analysis and a meta-regression: assessment method, geographical region, country income, exclusion criteria, study quality, age, sex, publication year, and sample size. Results: The literature search identified 8539 records, of which 225 were included. The adjusted prevalence was significantly lower in males than females. Across 44 countries, 12 assessment methods were used; the HIV-associated neurocognitive disorder/Frascati criteria, known for high false-positive rates, was employed in 44.4% of studies. The pooled cognitive impairment prevalence estimate in PWH, including asymptomatic cases, was 39.6% (95% confidence interval: 37.2-42.1%; range: 7-87%). The meta-regression explained 13.3% of between-study variation, with substantial residual heterogeneity ( I2 = 97.7%). Conclusion: Lack of data from more than 70% of the world's countries, cohorts being unselected for symptoms in most research studies, and limitations of the HIV-associated neurocognitive disorder/Frascati criteria restrict the ability to accurately determine the global burden of cognitive impairment in PWH. More studies in low-resource settings and a standardized approach to assessing cognitive impairment, bridging research and clinical realms, are needed.
MeSH term(s)	Humans ; HIV Infections/complications ; Geography ; Research Design ; Cognitive Dysfunction/epidemiology
Language	English
Publishing date	2022-09-15
Publishing country	England
Document type	Systematic Review ; Meta-Analysis ; Journal Article
ZDB-ID	639076-6
ISSN	1473-5571 ; 0269-9370 ; 1350-2840
ISSN (online)	1473-5571
ISSN	0269-9370 ; 1350-2840
DOI	10.1097/QAD.0000000000003379
Database	MEDical Literature Analysis and Retrieval System OnLINE

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