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Article ; Online: Children's Oncology Group's 2023 blueprint for research: Surgery.

Gow, Kenneth W / Lautz, Timothy B / Malek, Marcus M / Cost, Nicholas G / Newman, Erika A / Dasgupta, Roshni / Christison-Lagay, Emily R / Tiao, Gregory M / Davidoff, Andrew M

Pediatric blood & cancer

2023 Volume 71, Issue 3, Page(s) e30766

Abstract: Surgery plays a crucial role in the treatment of children with solid malignancies. A well-conducted operation is often essential for cure. Collaboration with the primary care team is important for determining if and when surgery should be performed, and ... ...

Abstract	Surgery plays a crucial role in the treatment of children with solid malignancies. A well-conducted operation is often essential for cure. Collaboration with the primary care team is important for determining if and when surgery should be performed, and if performed, an operation must be done in accordance with well-established standards. The long-term consequences of surgery also need to be considered. Indications and objectives for a procedure vary. Providing education and developing and analyzing new research protocols that include aims relevant to surgery are key objectives of the Surgery Discipline of the Children's Oncology Group. The critical evaluation of emerging technologies to ensure safe, effective procedures is another key objective. Through research, education, and advancing technologies, the role of the pediatric surgeon in the multidisciplinary care of children with solid malignancies will continue to evolve.
MeSH term(s)	Child ; Humans ; Neoplasms/surgery ; Medical Oncology
Language	English
Publishing date	2023-11-10
Publishing country	United States
Document type	Journal Article
ZDB-ID	2131448-2
ISSN	1545-5017 ; 1545-5009
ISSN (online)	1545-5017
ISSN	1545-5009
DOI	10.1002/pbc.30766
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Article: Training in a Hot Environment Fails to Elicit Changes in the Blood Oxidative Stress Response.

Williamson-Reisdorph, Cassie M / Quindry, Tiffany S / Christison, Katherine S / Gurney, Shae C / Tiemessen, Kathryn G / Cuddy, John / Hailes, Walter / Slivka, Dustin / Ruby, Brent C / Quindry, John C

Journal of human kinetics

2023 Volume 87, Page(s) 81–92

Abstract: Environmental temperature can impact exercise-induced blood oxidative stress; however, the effects of heat acclimation on this response have not been fully elucidated. The purpose of the study was to investigate the effects of hot (33°C) and room ... ...

Abstract	Environmental temperature can impact exercise-induced blood oxidative stress; however, the effects of heat acclimation on this response have not been fully elucidated. The purpose of the study was to investigate the effects of hot (33°C) and room temperature (20°C) environments on post-exercise blood oxidative stress responses following 15 temperature acclimation sessions. Untrained participants (n = 38, 26 ± 7 years, VO
Language	English
Publishing date	2023-04-20
Publishing country	Poland
Document type	Journal Article
ZDB-ID	2503989-1
ISSN	1899-7562 ; 1640-5544
ISSN (online)	1899-7562
ISSN	1640-5544
DOI	10.5114/jhk/161586
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Article ; Online: Rare Tumors: Opportunities and challenges from the Children's Oncology Group perspective.

EJC paediatric oncology

2023 Volume 2

Abstract: While all childhood cancers are rare, tumors that are particularly infrequent or underrepresented within pediatrics are studied under the umbrella of the Children's Oncology Group Rare Tumor committee, divided into the Retinoblastoma and Infrequent Tumor ...

Abstract	While all childhood cancers are rare, tumors that are particularly infrequent or underrepresented within pediatrics are studied under the umbrella of the Children's Oncology Group Rare Tumor committee, divided into the Retinoblastoma and Infrequent Tumor subcommittees. The Infrequent Tumor subcommittee has traditionally included an emphasis on globally rare tumors such as adrenocortical carcinoma, nasopharyngeal carcinoma, or those tumors that are rare in young children, despite being common in adolescents and young adults, such as colorectal carcinoma, thyroid carcinoma, and melanoma. Pleuropulmonary blastoma, gonadal stromal tumors, pancreatic tumors including pancreatoblastoma, gastrointestinal stromal tumor, nonmelanoma skin cancers, neuroendocrine tumors, and desmoplastic small round cell tumors, as well as other carcinomas are also included under the heading of the Children's Oncology Group Rare Tumor committee. While substantial challenges exist in rare cancers, inclusion and global collaboration remain key priorities to ensure high quality research to advance care.
Language	English
Publishing date	2023-07-20
Publishing country	Netherlands
Document type	Journal Article
ISSN	2772-610X
ISSN (online)	2772-610X
DOI	10.1016/j.ejcped.2023.100024
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Article ; Online: Gyrodactylus molweni sp. n. (Monogenea

Kevin W. Christison / David B. Vaughan / Andrew P. Shinn / Haakon Hansen

International Journal for Parasitology: Parasites and Wildlife, Vol 15, Iss , Pp 87-

Gyrodactylidae) from Chelon richardsonii (Smith, 1846) (Mugilidae) from Table Bay, South Africa

2021 Volume 94

Abstract: ... other Gyrodactylus species described from grey mullets globally namely G. zhukovi Ling, 1963 and G. mugili Zhukov ... 1970 from Planiliza haematocheila (Temminck and Schlegel, 1845); G. mugelus Rawson, 1973 ... from Mugil cephalus L.; G. curemae Conroy and Conroy, 1985 from Mugil curema Valenciennes, 1836 and G. xiamenensis ...

Abstract	Gyrodactylus molweni sp. n. is described from the body surface and fins of the South African mullet, Chelon richardsonii (Smith, 1846) collected from Table Bay Harbour, Cape Town and is compared to five other Gyrodactylus species described from grey mullets globally namely G. zhukovi Ling, 1963 and G. mugili Zhukov, 1970 from Planiliza haematocheila (Temminck and Schlegel, 1845); G. mugelus Rawson, 1973 from Mugil cephalus L.; G. curemae Conroy and Conroy, 1985 from Mugil curema Valenciennes, 1836 and G. xiamenensis Zang,Yang and Liu, 2001 from Planiliza macrolepis (Smith, 1846). Morphologically, G. molweni sp. n. has prominent ventral bar processes that near cover the hamulus roots, marginal sickles with large rhomboid heels, slender shafts and fine points that extend beyond the sickle toes. Gyrodactylus molweni sp. n. can, however, be readily differentiated: G. mugili and G. xiamenensis have ventral bars with small ventral processes; G. zhukovi has marginal hooks sickles with slender shafts and proportionately short points and open-faced blades; G. mugelus possesses marginal hook sickles with deep, rounded heels, forward slanting shafts and an angular, square line to the inner face of the blades. Although the length of the marginal hooks of G. curemae are similar to G. molweni sp. n., their hamuli are double the size. A GenBank BlastN search with the 931 bp sequence covering ITS1, 5.8S and ITS2 gave no close hits; the nearest species for which sequences are available is G. nipponensis Ogawa and Egusa, 1978 (identity 96.56%, 899/931 bp). The proposal of G. molweni sp. n. as a new species, therefore, is well supported by both the molecular and morphological analyses presented herein. This Gyrodactylus species is the first to be described from C. richardsonii and only the second Gyrodactylus species to be described from the marine environment off the African continent.
Keywords	Marine ; Intertidal fish ; South African mullet ; Grey mullet ; Zoology ; QL1-991
Subject code	590
Language	English
Publishing date	2021-08-01T00:00:00Z
Publisher	Elsevier
Document type	Article ; Online
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Article: Requiring a one-week addiction treatment experience in a six-week psychiatry clerkship: effects on attitudes toward substance-abusing patients.

Christison, George W / Haviland, Mark G

Teaching and learning in medicine

2003 Volume 15, Issue 2, Page(s) 93–97

Abstract: Background: Medical education shapes students' attitudes toward substance-abusing patients, often in negative ways. Curricular interventions to foster more positive attitudes toward such patients and their treatment can have lasting effects on clinical ... ...

Abstract	Background: Medical education shapes students' attitudes toward substance-abusing patients, often in negative ways. Curricular interventions to foster more positive attitudes toward such patients and their treatment can have lasting effects on clinical practice. The nature and duration of such interventions, however, requires clarification. Purpose: To test the hypothesis that spending 1 week of a 6-week psychiatry clerkship on an addication treatment site would improve attitudes toward substance-abusing patients without reducing the clerkship's benefits on attitudes toward, and knowledge about, psychiatry patients. Method: Using the Medical Condition Regard Scale, preclerkship and postclerkship attitudes toward patients with alcoholism, major depression, and emphysema (a control condition) were examined in 3rd-year medical students following the conversion of 1 of the clerkship's weeks to an addiction treatment site assignment. Psychiatric knowledge was assessed by comparing scores on the Psychiatry Subject examination before and after the change. Results: Mean regard scores increased significantly for patients with alcoholism and for patients with major depression but did not change for patients with emphysema. Subject examination scores before and after the curriculum change were not significantly different. Conclusions: Spending 1 week of a 6-week psychiatry clerkship on an addiction treatment site increased regard for patients with alcoholism without adversely affecting measures of attitudes toward, and knowledge about, psychiatric patients.
MeSH term(s)	Alcoholism/therapy ; Attitude of Health Personnel ; Clinical Clerkship ; Depressive Disorder/therapy ; Education, Medical, Undergraduate/methods ; Educational Measurement ; Humans ; Psychiatry/education ; Pulmonary Emphysema/therapy
Language	English
Publishing date	2003
Publishing country	United States
Document type	Journal Article
ZDB-ID	1038640-3
ISSN	1532-8015 ; 1040-1334
ISSN (online)	1532-8015
ISSN	1040-1334
DOI	10.1207/S15328015TLM1502_04
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Article ; Online: Electronic Gaming Characteristics Associated with Class 3 Severe Obesity in Youth Who Attend the Pediatric Weight Management Programs of the COMPASS Network.

Phan, Thao-Ly T / Tucker, Jared M / Siegel, Robert / Christison, Amy L / Stratbucker, William / Werk, Lloyd N / Hossain, Jobayer / Datto, George / Gentile, Douglas A / Stubblefield, Sam

Childhood obesity (Print)

2018 Volume 15, Issue 1, Page(s) 21–30

Abstract: Background: The prevalence of severe obesity and electronic game use among youth has increased over time.: Methods: We administered a survey assessing gaming and psycho-demographic characteristics to youth aged 11-17 attending five weight management ... ...

Abstract	Background: The prevalence of severe obesity and electronic game use among youth has increased over time. Methods: We administered a survey assessing gaming and psycho-demographic characteristics to youth aged 11-17 attending five weight management programs. We conducted chi-square and logistic regression analyses to describe the association between class 3 severe obesity and gaming characteristics. Results: Four hundred twelve youth (51% female, 26% Black, 25% Hispanic, 43% White, and 44% with class 3 severe obesity) completed the survey. There was a stepwise relationship between time spent gaming and class 3 severe obesity, with 28% of those playing 2 to <4 hours a day, 48% of those playing 4 to <6 hours a day, and 56% of those playing ≥6 hours a day having class 3 severe obesity (p = 0.002). Compared to youth without class 3 severe obesity, youth with class 3 severe obesity were more likely to have a TV in the bedroom (76% vs. 63%, p = 0.004) and play games on a console (39% vs. 27%, p = 0.03) and were less likely to report parental limit setting on type of games played (7% vs. 16%, p = 0.006). Youth who played games ≥4 hours a day were 1.94 times (95% confidence interval 1.27-3.00) more likely to have class 3 severe obesity than those who played <4 hours a day, after adjustment for demographic, behavioral, and academic variables. Conclusions: Our study demonstrates a clear association between gaming characteristics, especially time spent gaming, and severe obesity in youth. Further research testing family-based interventions that target gaming behaviors in youth are needed.
MeSH term(s)	Adolescent ; Adolescent Behavior/psychology ; Body Mass Index ; Child ; Cross-Sectional Studies ; Female ; Humans ; Male ; Obesity, Morbid/epidemiology ; Obesity, Morbid/etiology ; Obesity, Morbid/psychology ; Pediatric Obesity/epidemiology ; Pediatric Obesity/etiology ; Pediatric Obesity/psychology ; Sedentary Behavior ; Time Factors ; Video Games ; Weight Reduction Programs
Language	English
Publishing date	2018-09-29
Publishing country	United States
Document type	Journal Article ; Research Support, N.I.H., Extramural
ZDB-ID	2639910-6
ISSN	2153-2176 ; 2153-2168
ISSN (online)	2153-2176
ISSN	2153-2168
DOI	10.1089/chi.2018.0156
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Article ; Online: Social/Electronic Media Use of Children and Adolescents Who Attend the Pediatric Weight Management Programs of the COMPASS Network.

Siegel, Robert / Fals, Angela / Mirza, Nazrat / Datto, George / Stratbucker, William / Ievers-Landis, Carolyn E / Christison, Amy / Wang, Yu / Woolford, Susan J

Childhood obesity (Print)

2015 Volume 11, Issue 5, Page(s) 624–629

Abstract: Background: Obesity is a major healthcare problem in youth and their social/electronic media (SEM) use has been described as a risk factor. Though much is known about the newer technologies youth use to communicate, little is known about what is used by ...

Abstract	Background: Obesity is a major healthcare problem in youth and their social/electronic media (SEM) use has been described as a risk factor. Though much is known about the newer technologies youth use to communicate, little is known about what is used by those in weight management programs. The aim of this study was to determine what types of SEM, including sedentary and active video games, youth in weight management programs use and which they prefer for communicating with healthcare providers. Methods/design: This was a multisite study using a 24-question online SurveyMonkey® questionnaire. Youth, 12-17 years old, attending pediatric weight management programs at seven participating centers in the Childhood Obesity Multi Program Analysis and Study System network were eligible. Results: There were 292 responders with a mean age of 14.2 years. Fifty-four percent were female, 36% Caucasian, 35% African American, and 33% were Hispanic. Ninety-four percent had access to a computer, 71% had Internet access, and 63% had smartphones. Whereas 87% had at least one gaming system at home, 50% reported they never played sedentary video games (71% of females vs. 25% males; p < 0.0001) and 63% never played exercise video games during the week. The preferred method of communication with a healthcare provider was face to face (60%), with few indicating a preference for communication by texting (13%), phone (12%), or social media (6%). Conclusions: Face-to-face communication with healthcare providers is the preferred method for youth in pediatric weight management programs. They self-reported video game use less than previously described.
MeSH term(s)	Adolescent ; Adolescent Behavior/psychology ; Child ; Energy Metabolism ; Exercise ; Female ; Health Surveys ; Humans ; Male ; Pediatric Obesity/etiology ; Pediatric Obesity/prevention & control ; Pediatric Obesity/psychology ; Program Evaluation ; Recreation ; Sedentary Lifestyle ; Sex Distribution ; Snacks ; Social Media ; Television ; United States/epidemiology ; Video Games ; Weight Reduction Programs
Language	English
Publishing date	2015-10
Publishing country	United States
Document type	Journal Article
ZDB-ID	2639910-6
ISSN	2153-2176 ; 2153-2168
ISSN (online)	2153-2176
ISSN	2153-2168
DOI	10.1089/chi.2015.0034
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Article: Gyrodactylus eyipayipi sp. n. (Monogenea: Gyrodactylidae) from Syngnathus acus (Syngnathidae) from South Africa.

Vaughan, David B / Christison, Kevin W / Hansen, Haakon / Shinn, Andrew P

Folia parasitologica

2010 Volume 57, Issue 1, Page(s) 11–15

Abstract: ... syngnathiform hosts (G. pisculentus Williams, Kritsky, Dunnigan, Lash et Klein, 2008, G. shorti Holliman, 1963 ... and G. syngnathi Appleby, 1996). Although all four species have similar-sized and shaped attachment ... The marginal hooks of G. eyipayipi measure (mean) 30 pm in total length and are larger than those of the three ...

Abstract	Gyrodactylus eyipayipi sp. n. is described from the skin, gills, flute and male brood pouch of captive specimens of the greater pipefish Syngnathus acus L., collected for and maintained at the Two Oceans Aquarium in Cape Town, South Africa. It is the first marine Gyrodactylus species reported from the African continent. The new species is compared to the three known Gyrodactylus species affecting syngnathiform hosts (G. pisculentus Williams, Kritsky, Dunnigan, Lash et Klein, 2008, G. shorti Holliman, 1963, and G. syngnathi Appleby, 1996). Although all four species have similar-sized and shaped attachment hooks with some overlap, separation of the species is possible using marginal hook morphology. The marginal hooks of G. eyipayipi measure (mean) 30 pm in total length and are larger than those of the three other species (mean, 24-28 tm). Gyrodactylus eyipayipi can also be discriminated based on differences in the shape of the marginal hook sickle notably by its long sickle point which extends far beyond the toe, its blunt rounded toe and, by the approximate rectangular shape to the base of the sickle. By comparison, the sloping toe regions of G. pisculentus and G. syngnathi give the sickle bases an approximately triangular shape, whilst the short sickle point and open aperture to the sickles of G. shorti allow for their discrimination from G. eyipayipi.
MeSH term(s)	Animals ; Female ; Fish Diseases/epidemiology ; Fish Diseases/parasitology ; Male ; Parasitic Diseases, Animal/epidemiology ; Parasitic Diseases, Animal/parasitology ; Platyhelminths/anatomy & histology ; Platyhelminths/classification ; Smegmamorpha/parasitology ; South Africa/epidemiology ; Species Specificity
Language	English
Publishing date	2010-03-31
Publishing country	Czech Republic
Document type	Journal Article
ZDB-ID	162048-4
ISSN	0015-5683
ISSN	0015-5683
DOI	10.14411/fp.2010.002
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Article ; Online: Problem Video Gaming Among Children Enrolled in Tertiary Weight Management Programs.

Stubblefield, Sam / Datto, George / Phan, Thao-Ly T / Werk, Lloyd N / Stackpole, Kristin / Siegel, Robert / Stratbucker, William / Tucker, Jared M / Christison, Amy L / Hossain, Jobayer / Gentile, Douglas A

Cyberpsychology, behavior and social networking

2017 Volume 20, Issue 2, Page(s) 109–116

Abstract: ... that affect a child's ability to function (e.g., problem gaming), but none have examined the association ...

Abstract	Prior studies show seven percent to nine percent of children demonstrate gaming behaviors that affect a child's ability to function (e.g., problem gaming), but none have examined the association between problem gaming and weight status. The objective of this study was to determine the prevalence of problem gaming among children enrolled in tertiary weight management programs. We administered a computer-based survey to a convenience sample of children aged 11-17 years enrolled in five geographically diverse pediatric weight management (PWM) programs in the COMPASS (Childhood Obesity Multi-Program Analysis and Study System) network. The survey included demographics, gaming characteristics, and a problem gaming assessment. The survey had 454 respondents representing a diverse cohort (53 percent females, 27 percent black, 24 percent Hispanic, 41 percent white) with mean age of 13.7 years. A total of 8.2 percent of respondents met criteria for problem gaming. Problem gamers were more likely to be white, male, play mature-rated games, and report daily play. Children in PWM programs reported problem gaming at the same rate as other pediatric populations. Screening for problem gaming provides an opportunity for pediatricians to address gaming behaviors that may affect the health of children with obesity who already are at risk for worsened health and quality of life.
MeSH term(s)	Adolescent ; Body Weight/physiology ; Child ; Cross-Sectional Studies ; Female ; Humans ; Male ; Obesity ; Video Games/statistics & numerical data
Language	English
Publishing date	2017-02
Publishing country	United States
Document type	Journal Article
ZDB-ID	2545735-4
ISSN	2152-2723 ; 2152-2715
ISSN (online)	2152-2723
ISSN	2152-2715
DOI	10.1089/cyber.2016.0386
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Article ; Online: Surgical tray optimization as a simple means to decrease perioperative costs.

Farrelly, James S / Clemons, Crystal / Witkins, Sherri / Hall, Walter / Christison-Lagay, Emily R / Ozgediz, Doruk E / Cowles, Robert A / Stitelman, David H / Caty, Michael G

The Journal of surgical research

2017 Volume 220, Page(s) 320–326

Abstract: Background: Health care spending in the US remains excessively high. Aside from complicated, large-scale efforts at health care cost reduction, there are still relatively simple ways in which individual hospitals can cut unnecessary costs from everyday ... ...

Abstract	Background: Health care spending in the US remains excessively high. Aside from complicated, large-scale efforts at health care cost reduction, there are still relatively simple ways in which individual hospitals can cut unnecessary costs from everyday operations. Inspired by recent publications, our group sought to decrease the costs associated with surgical instrument processing at a large, multihospital academic center. Methods: This was a single-site observational study conducted at a large academic medical center. At the study start, all attending surgeons within the section of pediatric surgery agreed to standardize the pediatric surgery trays and to eliminate instruments that were deemed unnecessary from each tray. A multidisciplinary start-up meeting was held, and this meeting included stakeholders from central sterile processing, operating room nursing, scrub technicians, and materials management along with all five pediatric surgeons. Each tray was addressed individually. Instruments were eliminated from trays only if there was unanimous agreement among all the surgeons in the group. If no instruments in a given surgical tray were deemed necessary, the entire tray was eliminated from sterile processing rotation. Feedback questionnaires were drafted by the multidisciplinary team that participated in the start-up meeting. Surgeons were allowed to request for certain instruments to be placed back into the trays at any time, and the questionnaires also allowed for free-hand comments. Surgical kit preparation time was obtained from the institutional barcode scanning system. The cost per second of sterile processing labor was calculated using regional median salary for sterile processing technicians in the state of Connecticut. Using the pediatric surgery section as the model unit, this method was then applied to pediatric urology, neurosurgery, spine surgery, and orthopedics. Results: The pediatric surgery section eliminated an average of 59.5% of instruments per tray, resulting in an overall reduction of 1826 (39.5%) instruments from rotation, 45,856 fewer instruments processed per year, and nine trays eliminated completely from regular rotation. Processing time for six commonly used trays was reduced by an average of 28.7%. The urology section eliminated 18 trays from regular rotation and 179 (10.1%) instruments in total. Pediatric orthopedics, neurosurgery, and spine sections eliminated 708 (17.1%), 560 (92.7%), and 31 (32.2%) instruments, respectively, resulting in approximately 18,804 fewer instruments processed per year. Among all five surgical sections, annual instrument cost avoidance after tray optimization was estimated at $53,193 to $531,929 using average instrument life spans ranging from 1-10 y. Negative feedback and requests for instrument replacement were both minimal on feedback questionnaires. Conclusions: Surgical tray optimization represents a relatively simple microsystem improvement that could result in significant hospital cost reduction. Although difficult to quantify, other gains from surgical kit optimization include decreased weight per tray, decreased materials cost, and decreased labor required to count, decontaminate, and pack surgical trays.
MeSH term(s)	Cost Savings ; Perioperative Care/economics ; Surgical Instruments/economics
Language	English
Publishing date	2017-08-12
Publishing country	United States
Document type	Journal Article ; Observational Study
ZDB-ID	80170-7
ISSN	1095-8673 ; 0022-4804
ISSN (online)	1095-8673
ISSN	0022-4804
DOI	10.1016/j.jss.2017.06.029
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