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  1. Article: Managing yards for mammals: Mammal species richness peaks in the suburbs

    Grade, Aaron M. / Warren, Paige S. / Lerman, Susannah B.

    Elsevier B.V. Landscape and urban planning. 2022 Apr., v. 220

    2022  

    Abstract: Increased urbanization drives habitat loss, yet residential land-use represents significant habitat potential for mammals and could provide connectivity between patches of green spaces. Diverse mammal communities exist across urban gradients, but it is ... ...

    Abstract Increased urbanization drives habitat loss, yet residential land-use represents significant habitat potential for mammals and could provide connectivity between patches of green spaces. Diverse mammal communities exist across urban gradients, but it is unclear how mammal community composition varies within residential lands. We conducted a camera trapping study in 36 residential yards across an urban gradient to assess the relative contributions of the degree of urbanization in the land-use context versus parcel habitat features, such as vegetation structure, on mammal community diversity and composition. We hypothesized that land-use context would more strongly influence mammal community metrics than parcel features, and that there would be species-specific differences in response. We detected 14 non-domesticated mammal species and found that species richness peaked in the suburbs and tapered off at the rural and urban ends of the gradient in accordance with patterns seen in other taxonomic groups, yet rarely quantified in mammals. Large-bodied interior forest species were associated with rural sites, urban-dwelling species were associated with urban sites, and suburban sites had an overlap of species types. Although composition of mammal species in residential yards appears to be strongly related to land-use context, which is often outside of residents’ control, management of parcel habitat features such as retention of large mature trees may facilitate connectivity between patches of habitat across urbanizing landscapes. Informed residential yard management remains an important tool for urban wildlife management in an era of global change.
    Keywords cameras ; community structure ; forests ; global change ; habitat destruction ; habitats ; land use ; landscapes ; mammals ; species richness ; urbanization ; vegetation structure ; wildlife management
    Language English
    Dates of publication 2022-04
    Publishing place Elsevier B.V.
    Document type Article
    ZDB-ID 742504-1
    ISSN 1872-6062 ; 0169-2046
    ISSN (online) 1872-6062
    ISSN 0169-2046
    DOI 10.1016/j.landurbplan.2021.104337
    Database NAL-Catalogue (AGRICOLA)

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  2. Article ; Online: Evaluating the use of semi-structured crowdsourced data to quantify inequitable access to urban biodiversity: A case study with eBird.

    Grade, Aaron M / Chan, Nathan W / Gajbhiye, Prashikdivya / Perkins, Deja J / Warren, Paige S

    PloS one

    2022  Volume 17, Issue 11, Page(s) e0277223

    Abstract: Credibly estimating social-ecological relationships requires data with broad coverage and fine geographic resolutions that are not typically available from standard ecological surveys. Open and unstructured data from crowdsourced platforms offer an ... ...

    Abstract Credibly estimating social-ecological relationships requires data with broad coverage and fine geographic resolutions that are not typically available from standard ecological surveys. Open and unstructured data from crowdsourced platforms offer an opportunity for collecting large quantities of user-submitted ecological data. However, the representativeness of the areas sampled by these data portals is not well known. We investigate how data availability in eBird, one of the largest and most popular crowdsourced science platforms, correlates with race and income of census tracts in two cities: Boston, MA and Phoenix, AZ. We find that checklist submissions vary greatly across census tracts, with similar patterns within both metropolitan regions. In particular, census tracts with high income and high proportions of white residents are most likely to be represented in the data in both cities, which indicates selection bias in eBird coverage. Our results illustrate the non-representativeness of eBird data, and they also raise deeper questions about the validity of statistical inferences regarding disparities that can be drawn from such datasets. We discuss these challenges and illustrate how sample selection problems in unstructured or semi-structured crowdsourced data can lead to spurious conclusions regarding the relationships between race, income, and access to urban bird biodiversity. While crowdsourced data are indispensable and complementary to more traditional approaches for collecting ecological data, we conclude that unstructured or semi-structured data may not be well-suited for all lines of inquiry, particularly those requiring consistent data coverage, and should thus be handled with appropriate care.
    MeSH term(s) Crowdsourcing ; Biodiversity ; Cities ; Social Environment ; Boston
    Language English
    Publishing date 2022-11-09
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2267670-3
    ISSN 1932-6203 ; 1932-6203
    ISSN (online) 1932-6203
    ISSN 1932-6203
    DOI 10.1371/journal.pone.0277223
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Effect of the Extended Focused Assessment With Sonography for Trauma on the Screening Performance of the National Emergency X-Radiography Utilization Study Chest Decision Instrument.

    Grade, Madeline M / Ehlers, Paul F / Kornblith, Aaron E / Mower, William R / Raja, Ali S / Schleifer, Jessica / Liteplo, Andrew / Rodriguez, Robert M

    Annals of emergency medicine

    2023  Volume 81, Issue 4, Page(s) 495–500

    Abstract: Study objective: Developed to decrease unnecessary thoracic computed tomography use in adult blunt trauma patients, the National Emergency X-Radiography Utilization Study (NEXUS) Chest clinical decision instrument does not include the extended Focused ... ...

    Abstract Study objective: Developed to decrease unnecessary thoracic computed tomography use in adult blunt trauma patients, the National Emergency X-Radiography Utilization Study (NEXUS) Chest clinical decision instrument does not include the extended Focused Assessment with Sonography in Trauma (eFAST). We assessed whether eFAST improves the NEXUS Chest clinical decision instrument's diagnostic performance and may replace the chest radiograph (CXR) as a predictor variable.
    Methods: We performed a secondary analysis of prospective data from 8 Level I trauma centers from 2011-2014. We compared performance of modified clinical decision instruments that (1) added eFAST as a predictor (eFAST-added clinical decision instrument), and (2) replaced CXR with eFAST (eFAST-replaced clinical decision instrument), in screening for blunt thoracic injuries.
    Results: One thousand nine hundred fifty-seven patients had documented computed tomography, CXR, clinical NEXUS criteria, and adequate eFAST; 624 (31.9%) patients had blunt thoracic injuries, and 126 (6.4%) had major injuries. Compared to the NEXUS Chest clinical decision instrument, the eFAST-added clinical decision instrument demonstrated unchanged screening performance for major injury (sensitivity 0.98 [0.94 to 1.00], specificity 0.28 [0.26 to 0.30]) or any injury (sensitivity 0.97 [0.95 to 0.98], specificity 0.21 [0.19 to 0.23]). The eFAST-replaced clinical decision instrument demonstrated unchanged sensitivity for major injury (sensitivity 0.93 [0.87 to 0.97], specificity 0.31 [0.29 to 0.34]) and decreased sensitivity for any injury (0.93 [0.91 to 0.951] versus 0.97 [0.953 to 0.98]).
    Conclusion: In our secondary analysis, adding eFAST as a predictor variable did not improve the diagnostic screening performance of the original NEXUS Chest clinical decision instrument; eFAST cannot replace the CXR criterion of the NEXUS Chest clinical decision instrument.
    MeSH term(s) Adult ; Humans ; Focused Assessment with Sonography for Trauma ; Prospective Studies ; Sensitivity and Specificity ; Thoracic Injuries/diagnostic imaging ; Radiography, Thoracic/methods ; Wounds, Nonpenetrating/diagnostic imaging
    Language English
    Publishing date 2023-02-07
    Publishing country United States
    Document type Journal Article ; Research Support, U.S. Gov't, P.H.S.
    ZDB-ID 603080-4
    ISSN 1097-6760 ; 0196-0644
    ISSN (online) 1097-6760
    ISSN 0196-0644
    DOI 10.1016/j.annemergmed.2022.09.027
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Perilous choices

    Aaron M. Grade / Susannah B. Lerman / Paige S. Warren

    Ecosphere, Vol 12, Iss 7, Pp n/a-n/a (2021)

    landscapes of fear for adult birds reduces nestling condition across an urban gradient

    2021  

    Abstract: Abstract Predator fear effects influence reproductive outcomes in many species. In non‐urban systems, passerines often respond to predator cues by reducing parental investment, resulting in smaller and lighter nestlings. Since trophic interactions in ... ...

    Abstract Abstract Predator fear effects influence reproductive outcomes in many species. In non‐urban systems, passerines often respond to predator cues by reducing parental investment, resulting in smaller and lighter nestlings. Since trophic interactions in urban areas are highly altered, it is unclear how passerines respond to fear effects in human‐altered landscapes. Nestlings of passerines in urban areas also tend to be smaller and lighter than their rural counterparts and are often exposed to high densities of potential predators yet experience lower per capita predation—the predation paradox. We suggest fear effects in urban habitats could be a significant mechanism influencing nestling condition in birds, despite lowered predation rates. We manipulated exposure of nesting birds to adult‐consuming predator risk in residential yards across a gradient of urbanization to determine the relative influence of urbanization and fear on nestling condition. We found nestlings had reduced mass in nests exposed to predator playbacks as well as in more urban areas. Despite lower per capita predation rates in urban areas, fear effects from increased predator densities may influence passerine fitness through reduced nestling condition. As urban development expands, biodiversity conservation hinges on a deeper mechanistic understanding of how urbanization affects reproductive outcomes.
    Keywords behavior ; birds ; fear effects ; house wren ; non‐lethal effects ; Troglodytes aedon ; Ecology ; QH540-549.5
    Language English
    Publishing date 2021-07-01T00:00:00Z
    Publisher Wiley
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article: Perilous choices: landscapes of fear for adult birds reduces nestling condition across an urban gradient

    Grade, Aaron M. / Lerman, Susannah B. / Warren, Paige S.

    Ecosphere. 2021 July, v. 12, no. 7

    2021  

    Abstract: Predator fear effects influence reproductive outcomes in many species. In non‐urban systems, passerines often respond to predator cues by reducing parental investment, resulting in smaller and lighter nestlings. Since trophic interactions in urban areas ... ...

    Abstract Predator fear effects influence reproductive outcomes in many species. In non‐urban systems, passerines often respond to predator cues by reducing parental investment, resulting in smaller and lighter nestlings. Since trophic interactions in urban areas are highly altered, it is unclear how passerines respond to fear effects in human‐altered landscapes. Nestlings of passerines in urban areas also tend to be smaller and lighter than their rural counterparts and are often exposed to high densities of potential predators yet experience lower per capita predation—the predation paradox. We suggest fear effects in urban habitats could be a significant mechanism influencing nestling condition in birds, despite lowered predation rates. We manipulated exposure of nesting birds to adult‐consuming predator risk in residential yards across a gradient of urbanization to determine the relative influence of urbanization and fear on nestling condition. We found nestlings had reduced mass in nests exposed to predator playbacks as well as in more urban areas. Despite lower per capita predation rates in urban areas, fear effects from increased predator densities may influence passerine fitness through reduced nestling condition. As urban development expands, biodiversity conservation hinges on a deeper mechanistic understanding of how urbanization affects reproductive outcomes.
    Keywords Passeriformes ; adults ; biodiversity conservation ; fearfulness ; predation ; risk ; urbanization
    Language English
    Dates of publication 2021-07
    Publishing place John Wiley & Sons, Ltd
    Document type Article
    Note JOURNAL ARTICLE
    ZDB-ID 2572257-8
    ISSN 2150-8925
    ISSN 2150-8925
    DOI 10.1002/ecs2.3665
    Database NAL-Catalogue (AGRICOLA)

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  6. Article ; Online: When the birds go unheard: highway noise disrupts information transfer between bird species.

    Grade, Aaron M / Sieving, Kathryn E

    Biology letters

    2016  Volume 12, Issue 4

    Abstract: Highway infrastructure and accompanying vehicle noise is associated with decreased wildlife populations in adjacent habitats. Noise masking of animal communication is an oft-cited potential mechanism underlying species loss in sound-polluted habitats. ... ...

    Abstract Highway infrastructure and accompanying vehicle noise is associated with decreased wildlife populations in adjacent habitats. Noise masking of animal communication is an oft-cited potential mechanism underlying species loss in sound-polluted habitats. This study documents the disruption of between-species information transfer by anthropogenic noise. Titmice and chickadees broadcast specific calls to alert kin of predator threats, and sympatric vertebrates eavesdrop on these alarm calls to avoid predators. We tested if tufted titmouse alarm call eavesdropping by northern cardinals is disrupted by road noise. We broadcast recorded alarm calls to cardinals in natural areas near and far from highways. Cardinals reliably produced predator avoidance responses in quiet trials, but all birds in noisy areas failed to respond, demonstrating that highway noise is loud enough to disrupt this type of survival-related information via masking or cognitive distraction. Birds in family Paridae are abundant, highly social and vocal residents of woodlands across the Holarctic whose alarm calls are used by many species to mediate predation risks. Our work suggests that communication network disruption is likely to be widespread, and could help explain the pattern of reduced biodiversity near roadways.
    MeSH term(s) Animal Communication ; Animals ; Noise/adverse effects ; Passeriformes/physiology ; Predatory Behavior ; Sound ; Vocalization, Animal
    Language English
    Publishing date 2016-04
    Publishing country England
    Document type Journal Article ; Research Support, U.S. Gov't, Non-P.H.S.
    ZDB-ID 2135022-X
    ISSN 1744-957X ; 1744-9561
    ISSN (online) 1744-957X
    ISSN 1744-9561
    DOI 10.1098/rsbl.2016.0113
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Is “Pishing” Tantamount to Mobbing? Black-Capped Chickadees Respond Similarly to Human Pishing and Conspecific Mobbing Calls in Rural and Suburban Forests

    Kerstens, Mark / Grade, Aaron M / Warren, Paige S

    Northeastern naturalist. 2019 Aug. 12, v. 26, no. 3

    2019  

    Abstract: Poecile atricapillus (Black-capped Chickadee) mobbing calls elicit mobbing events in which birds drive away a predator. Human birders simulate these calls by “pishing” (vocalizing mobbing calls) to coerce birds into view. We investigated whether pishing ... ...

    Abstract Poecile atricapillus (Black-capped Chickadee) mobbing calls elicit mobbing events in which birds drive away a predator. Human birders simulate these calls by “pishing” (vocalizing mobbing calls) to coerce birds into view. We investigated whether pishing is as salient as natural mobbing calls, and whether birds respond differently in suburban forest fragments than in intact forests. Using experimental playbacks, we broadcast mobbing calls and pishing calls in suburban forest patches and intact forests and measured Chickadee response. We found that Chickadees had significantly stronger responses to mobbing calls than to alarm calls used as a positive control, but pishing call response was not significantly different than mobbing or control alarm call responses. We also saw no difference in number of Chickadees responding between suburban fragments and intact forests, but we did see a difference in areas with denser vegetation. These findings show that pishing may be less urgent than Chickadee mobbing calls but may still contribute to stress and energetic demands on birds.
    Keywords antipredatory behavior ; birds ; forests ; habitat fragmentation ; humans ; Poecile atricapillus ; vocalization
    Language English
    Dates of publication 2019-0812
    Size p. 580-592.
    Publishing place Humboldt Field Research Institute
    Document type Article
    ZDB-ID 2117206-7
    ISSN 1938-5307 ; 1092-6194
    ISSN (online) 1938-5307
    ISSN 1092-6194
    DOI 10.1656/045.026.0311
    Database NAL-Catalogue (AGRICOLA)

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  8. Article ; Online: The rectal cancer microRNAome--microRNA expression in rectal cancer and matched normal mucosa.

    Gaedcke, Jochen / Grade, Marian / Camps, Jordi / Søkilde, Rolf / Kaczkowski, Bogumil / Schetter, Aaron J / Difilippantonio, Michael J / Harris, Curtis C / Ghadimi, B Michael / Møller, Søren / Beissbarth, Tim / Ried, Thomas / Litman, Thomas

    Clinical cancer research : an official journal of the American Association for Cancer Research

    2012  Volume 18, Issue 18, Page(s) 4919–4930

    Abstract: Purpose: miRNAs play a prominent role in a variety of physiologic and pathologic biologic processes, including cancer. For rectal cancers, only limited data are available on miRNA expression profiles, whereas the underlying genomic and transcriptomic ... ...

    Abstract Purpose: miRNAs play a prominent role in a variety of physiologic and pathologic biologic processes, including cancer. For rectal cancers, only limited data are available on miRNA expression profiles, whereas the underlying genomic and transcriptomic aberrations have been firmly established. We therefore, aimed to comprehensively map the miRNA expression patterns of this disease.
    Experimental design: Tumor biopsies and corresponding matched mucosa samples were prospectively collected from 57 patients with locally advanced rectal cancers. Total RNA was extracted, and tumor and mucosa miRNA expression profiles were subsequently established for all patients. The expression of selected miRNAs was validated using semi-quantitative real-time PCR.
    Results: Forty-nine miRNAs were significantly differentially expressed (log(2)-fold difference >0.5 and P < 0.001) between rectal cancer and normal rectal mucosa. The predicted targets for these miRNAs were enriched for the following pathways: Wnt, TGF-beta, mTOR, insulin, mitogen-activated protein kinase, and ErbB signaling. Thirteen of these 49 miRNAs seem to be rectal cancer-specific, and have not been previously reported for colon cancers: miR-492, miR-542-5p, miR-584, miR-483-5p, miR-144, miR-2110, miR-652, miR-375, miR-147b, miR-148a, miR-190, miR-26a/b, and miR-338-3p. Of clinical impact, miR-135b expression correlated significantly with disease-free and cancer-specific survival in an independent multicenter cohort of 116 patients.
    Conclusion: This comprehensive analysis of the rectal cancer miRNAome uncovered novel miRNAs and pathways associated with rectal cancer. This information contributes to a detailed view of this disease. Moreover, the identification and validation of miR-135b may help to identify novel molecular targets and pathways for therapeutic exploitation.
    MeSH term(s) Cluster Analysis ; Colonic Neoplasms/genetics ; Gene Expression Profiling ; Gene Expression Regulation, Neoplastic ; Gene Regulatory Networks ; Humans ; Intestinal Mucosa/metabolism ; Intestinal Mucosa/pathology ; MicroRNAs/genetics ; Prognosis ; Rectal Neoplasms/genetics ; Rectal Neoplasms/mortality ; Rectal Neoplasms/pathology ; Rectum/metabolism ; Rectum/pathology ; Reproducibility of Results
    Chemical Substances MIRN135 microRNA, human ; MicroRNAs
    Language English
    Publishing date 2012-07-31
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Intramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 1225457-5
    ISSN 1557-3265 ; 1078-0432
    ISSN (online) 1557-3265
    ISSN 1078-0432
    DOI 10.1158/1078-0432.CCR-12-0016
    Database MEDical Literature Analysis and Retrieval System OnLINE

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