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Article ; Online: Which influenza viruses will emerge following the SARS-CoV-2 pandemic?

Laurie, Karen L / Rockman, Steve

2021 Volume 15, Issue 5, Page(s) 573–576

Abstract: The world has experienced five pandemics in just over one hundred years, four due to influenza and one due to coronavirus (SARS-CoV-2). In each case of pandemic influenza, the pandemic influenza strain has replaced the previous seasonal influenza virus. ... ...

Abstract	The world has experienced five pandemics in just over one hundred years, four due to influenza and one due to coronavirus (SARS-CoV-2). In each case of pandemic influenza, the pandemic influenza strain has replaced the previous seasonal influenza virus. Notably, throughout the SARS-CoV-2 pandemic, there has been a 99% reduction in influenza isolation globally. It is anticipated that influenza will re-emerge following the SARS-CoV-2 pandemic and circulate again. The potential for which influenza viruses will emerge is examined.
MeSH term(s)	COVID-19 ; Humans ; Influenza, Human/epidemiology ; Influenza, Human/virology ; Orthomyxoviridae/classification ; Pandemics
Language	English
Publishing date	2021-05-06
Publishing country	England
Document type	Journal Article
ZDB-ID	2274538-5
ISSN	1750-2659 ; 1750-2640
ISSN (online)	1750-2659
ISSN	1750-2640
DOI	10.1111/irv.12866
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Article: Playing With Code: An Innovative Way to Teach Numeracy and Early Math Concepts to Young DHH Children in the 21st Century.

Kritzer, Karen L / Green, Laurie

American annals of the deaf

2021 Volume 166, Issue 3, Page(s) 409–423

Abstract: While focusing on numeracy is essential in preschool classrooms with deaf and hard of hearing (DHH) children, it is also important that concepts of numeracy be taught in a way that incorporates executive functions, introduces computational thinking, and ... ...

Abstract	While focusing on numeracy is essential in preschool classrooms with deaf and hard of hearing (DHH) children, it is also important that concepts of numeracy be taught in a way that incorporates executive functions, introduces computational thinking, and prepares students for life in a 21st-century world. Technology-enhanced teaching resources (e.g., Code-a-pillar, Bee-Bot, Kubo) provide coding opportunities that engage young children in problem solving, planning, and organization. These tools provide kinesthetic experiences in the exploration of early numeracy skills like counting, addition, subtraction, and estimation. The present article provides a rationale for including 21st-century teaching practices and educational technology resources in preschool classrooms with DHH children as one path toward strengthening early mathematics understanding. The authors also offer tips for teachers on how to select technology tools for classroom use and ways to integrate the use of these tools as part of meaningful mathematics instruction.
MeSH term(s)	Child, Preschool ; Humans ; Educational Status ; Mathematics ; Persons With Hearing Impairments ; Schools ; Students
Language	English
Publishing date	2021-11-23
Publishing country	United States
Document type	Journal Article
ZDB-ID	603610-7
ISSN	1543-0375 ; 0002-726X
ISSN (online)	1543-0375
ISSN	0002-726X
DOI	10.1353/aad.2021.0027
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Article ; Online: Ultraviolet vision in anemonefish improves colour discrimination.

Mitchell, Laurie J / Phelan, Amelia / Cortesi, Fabio / Marshall, N Justin / Chung, Wen-Sung / Osorio, Daniel C / Cheney, Karen L

The Journal of experimental biology

2024 Volume 227, Issue 7

Abstract: In many animals, ultraviolet (UV) vision guides navigation, foraging, and communication, but few studies have addressed the contribution of UV signals to colour vision, or measured UV discrimination thresholds using behavioural experiments. Here, we ... ...

Abstract	In many animals, ultraviolet (UV) vision guides navigation, foraging, and communication, but few studies have addressed the contribution of UV signals to colour vision, or measured UV discrimination thresholds using behavioural experiments. Here, we tested UV colour vision in an anemonefish (Amphiprion ocellaris) using a five-channel (RGB-V-UV) LED display. We first determined that the maximal sensitivity of the A. ocellaris UV cone was ∼386 nm using microspectrophotometry. Three additional cone spectral sensitivities had maxima at ∼497, 515 and ∼535 nm. We then behaviourally measured colour discrimination thresholds by training anemonefish to distinguish a coloured target pixel from grey distractor pixels of varying intensity. Thresholds were calculated for nine sets of colours with and without UV signals. Using a tetrachromatic vision model, we found that anemonefish were better (i.e. discrimination thresholds were lower) at discriminating colours when target pixels had higher UV chromatic contrast. These colours caused a greater stimulation of the UV cone relative to other cone types. These findings imply that a UV component of colour signals and cues improves their detectability, which likely increases the prominence of anemonefish body patterns for communication and the silhouette of zooplankton prey.
MeSH term(s)	Animals ; Color ; Color Vision ; Retinal Cone Photoreceptor Cells/physiology ; Color Perception/physiology ; Perciformes ; Ultraviolet Rays
Language	English
Publishing date	2024-04-08
Publishing country	England
Document type	Journal Article
ZDB-ID	218085-6
ISSN	1477-9145 ; 0022-0949
ISSN (online)	1477-9145
ISSN	0022-0949
DOI	10.1242/jeb.247425
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Article: Higher ultraviolet skin reflectance signals submissiveness in the anemonefish,

Mitchell, Laurie J / Cortesi, Fabio / Marshall, N Justin / Cheney, Karen L

Behavioral ecology : official journal of the International Society for Behavioral Ecology

2022 Volume 34, Issue 1, Page(s) 19–32

Abstract: Ultraviolet (UV) vision is widespread among teleost fishes, of which many exhibit UV skin colors for communication. However, aside from its role in mate selection, few studies have examined the information UV signaling conveys in other socio-behavioral ... ...

Abstract	Ultraviolet (UV) vision is widespread among teleost fishes, of which many exhibit UV skin colors for communication. However, aside from its role in mate selection, few studies have examined the information UV signaling conveys in other socio-behavioral contexts. Anemonefishes (subfamily, Amphiprioninae) live in a fascinating dominance hierarchy, in which a large female and male dominate over non-breeding subordinates, and body size is the primary cue for dominance. The iconic orange and white bars of anemonefishes are highly UV-reflective, and their color vision is well tuned to perceive the chromatic contrast of skin, which we show here decreases in the amount of UV reflectance with increasing social rank. To test the function of their UV-skin signals, we compared the outcomes of staged contests over dominance between size-matched Barrier Reef anemonefish (
Language	English
Publishing date	2022-11-01
Publishing country	United States
Document type	Journal Article
ZDB-ID	1496189-1
ISSN	1465-7279 ; 1045-2249
ISSN (online)	1465-7279
ISSN	1045-2249
DOI	10.1093/beheco/arac089
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Article ; Online: Translational toxicoepigenetic Meta-Analyses identify homologous gene DNA methylation reprogramming following developmental phthalate and lead exposure in mouse and human offspring.

Petroff, Rebekah L / Dolinoy, Dana C / Wang, Kai / Montrose, Luke / Padmanabhan, Vasantha / Peterson, Karen E / Ruden, Douglas M / Sartor, Maureen A / Svoboda, Laurie K / Téllez-Rojo, Martha M / Goodrich, Jaclyn M

Environment international

2024 Volume 186, Page(s) 108575

Abstract: Although toxicology uses animal models to represent real-world human health scenarios, a critical translational gap between laboratory-based studies and epidemiology remains. In this study, we aimed to understand the toxicoepigenetic effects on DNA ... ...

Abstract	Although toxicology uses animal models to represent real-world human health scenarios, a critical translational gap between laboratory-based studies and epidemiology remains. In this study, we aimed to understand the toxicoepigenetic effects on DNA methylation after developmental exposure to two common toxicants, the phthalate di(2-ethylhexyl) phthalate (DEHP) and the metal lead (Pb), using a translational paradigm that selected candidate genes from a mouse study and assessed them in four human birth cohorts. Data from mouse offspring developmentally exposed to DEHP, Pb, or control were used to identify genes with sex-specific sites with differential DNA methylation at postnatal day 21. Associations of human infant DNA methylation in homologous mouse genes with prenatal DEHP or Pb were examined with a meta-analysis. Differential methylation was observed on 6 cytosines (adjusted-p < 0.05) and 90 regions (adjusted-p < 0.001). This translational approach offers a unique method that can detect conserved epigenetic differences that are developmentally susceptible to environmental toxicants.
MeSH term(s)	Animals ; Female ; Humans ; Infant ; Male ; Mice ; Pregnancy ; Diethylhexyl Phthalate/toxicity ; DNA Methylation/drug effects ; Environmental Pollutants/toxicity ; Epigenesis, Genetic/drug effects ; Lead/toxicity ; Phthalic Acids/toxicity ; Prenatal Exposure Delayed Effects/genetics ; Prenatal Exposure Delayed Effects/chemically induced
Chemical Substances	Diethylhexyl Phthalate (C42K0PH13C) ; Environmental Pollutants ; Lead (2P299V784P) ; Phthalic Acids
Language	English
Publishing date	2024-03-11
Publishing country	Netherlands
Document type	Journal Article ; Meta-Analysis ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
ZDB-ID	554791-x
ISSN	1873-6750 ; 0160-4120
ISSN (online)	1873-6750
ISSN	0160-4120
DOI	10.1016/j.envint.2024.108575
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Article ; Online: Early-onset neonatal sepsis: Effectiveness of classification based on ante- and intrapartum risk factors and clinical monitoring.

Dalut, Laurie / Brunhes, Anne / Cambier, Sébastien / Gallot, Denis / Coste, Karen

Journal of gynecology obstetrics and human reproduction

2024 Volume 53, Issue 6, Page(s) 102775

Abstract: Introduction: In 2017, the French public health authority HAS published new guidelines for the management of newborns at risk of early bacterial neonatal infection. These guidelines were based on ante- and intrapartum risk factors and clinical ... ...

Abstract	Introduction: In 2017, the French public health authority HAS published new guidelines for the management of newborns at risk of early bacterial neonatal infection. These guidelines were based on ante- and intrapartum risk factors and clinical monitoring. In January 2021, we implemented a new protocol based on these guidelines in our tertiary maternity unit. Objectives: To assess the impact of the protocol implemented on neonates' antibiotic prescriptions. Method: An "old protocol" group comprising newborns hospitalized between July 1, 2020 and December 31, 2020, was compared to a "new protocol" group formed between January 14, 2021 and July 13, 2021. Data were collected on infectious risk factors, antibiotic prescriptions, and emergency room visits within 2 weeks for an infection or suspected infection. Results: The "old protocol" population comprised 1565 children and the "new protocol" population 1513. Antibiotic therapy was prescribed for 29 newborns (1.85 %) in the old protocol group versus 15 (0.99 %) in the new one (p = 0.05). The median duration was 5 days and 2 days respectively (p = 0.08). With the new protocol, newborns in category B were about 20 times more likely (p = 0.01), and those in category C about 54 times more likely (p = 0.005) to have an infection than those classified in categories N or A. Conclusion: This study demonstrates that clinical monitoring criteria enable reduced use and duration of antibiotic therapy and are reliable.
Language	English
Publishing date	2024-03-21
Publishing country	France
Document type	Journal Article
ISSN	2468-7847
ISSN (online)	2468-7847
DOI	10.1016/j.jogoh.2024.102775
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Article ; Online: Examining the differential protective effects of women's spirituality and religiosity on alcohol and marijuana use by sexual identity.

Drabble, Laurie A / Mericle, Amy A / Munroe, Cat / Cerezo, Alison / Karriker-Jaffe, Katherine J / Hughes, Tonda L / Trocki, Karen F

Addictive behaviors reports

2022 Volume 16, Page(s) 100450

Abstract: The current study explored how religiosity and spirituality may differentially influence substance use by sexual identity based on a sample of adult sexual minority women (SMW; n = 437 lesbian; n = 323 bisexual) relative to a heterosexual comparison ... ...

Abstract	The current study explored how religiosity and spirituality may differentially influence substance use by sexual identity based on a sample of adult sexual minority women (SMW; n = 437 lesbian; n = 323 bisexual) relative to a heterosexual comparison sample (n = 636). We examined three questions: (1) whether
Language	English
Publishing date	2022-08-13
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	2831558-3
ISSN	2352-8532 ; 2352-8532
ISSN (online)	2352-8532
ISSN	2352-8532
DOI	10.1016/j.abrep.2022.100450
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Article ; Online: Home Literacy Experiences and Shared Reading Practices: Preschoolers With Hearing Loss.

DesJardin, Jean L / Stika, Carren J / Eisenberg, Laurie S / Johnson, Karen C / Ganguly, Dianne Hammes / Henning, Shirley C

Journal of deaf studies and deaf education

2023 Volume 28, Issue 2, Page(s) 189–200

Abstract: Home literacy experiences and observed parent and child behaviors during shared book reading were investigated in preschool-age children with hearing loss and with typical hearing to examine the relationships between those factors and children's language ...

Abstract	Home literacy experiences and observed parent and child behaviors during shared book reading were investigated in preschool-age children with hearing loss and with typical hearing to examine the relationships between those factors and children's language skills. The methods involved parent-reported home literacy experiences and videotaped parent-child dyads during shared book reading. Children's language skills were tested using the Preschool Language Scale-4. The results indicated significant differences between groups for home literacy experiences and observed parent and child behaviors. Parents of children with hearing loss were found to read more frequently to their children than parents of children with typical hearing, yet scored lower for literacy strategies and teaching techniques compared to parents of children with typical hearing. Children with hearing loss scored lower in interactive reading behaviors compared to children with typical hearing. For children with hearing loss, frequency of book reading and child interactive reading behaviors were strong predictive factors for children's language skills. These results suggest that families of children with hearing loss would benefit from professional support as they read storybooks to their children. Similarly, children with hearing loss should be encouraged to be more interactive during shared book reading.
MeSH term(s)	Child, Preschool ; Humans ; Literacy ; Reading ; Hearing Loss ; Deafness ; Language
Language	English
Publishing date	2023-01-06
Publishing country	United States
Document type	Journal Article ; Research Support, N.I.H., Extramural
ZDB-ID	1494621-X
ISSN	1465-7325 ; 1081-4159
ISSN (online)	1465-7325
ISSN	1081-4159
DOI	10.1093/deafed/enac050
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Article ; Online: Harm from Others' Drinking Among Sexual Minority Adults in the United States.

Karriker-Jaffe, Katherine J / Drabble, Laurie / Trocki, Karen F / Hughes, Tonda L / Greenfield, Thomas K

LGBT health

2020 Volume 8, Issue 1, Page(s) 50–59

Abstract: Purpose: ...

Abstract	Purpose:
MeSH term(s)	Adult ; Alcohol Drinking/adverse effects ; Alcohol-Related Disorders/epidemiology ; Female ; Health Status Disparities ; Heterosexuality/statistics & numerical data ; Humans ; Male ; Middle Aged ; Prevalence ; Sexual and Gender Minorities/statistics & numerical data ; Surveys and Questionnaires ; United States/epidemiology
Language	English
Publishing date	2020-12-18
Publishing country	United States
Document type	Journal Article ; Research Support, N.I.H., Extramural
ZDB-ID	2727303-9
ISSN	2325-8306 ; 2325-8292
ISSN (online)	2325-8306
ISSN	2325-8292
DOI	10.1089/lgbt.2020.0011
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Article ; Online: Arsenic is a potent co-mutagen of ultraviolet light

Rachel M. Speer / Shuvro P. Nandi / Karen L. Cooper / Xixi Zhou / Hui Yu / Yan Guo / Laurie G. Hudson / Ludmil B. Alexandrov / Ke Jian Liu

Communications Biology, Vol 6, Iss 1, Pp 1-

2023 Volume 11

Abstract: Abstract Arsenic enhances the carcinogenicity of ultraviolet radiation (UVR). However, the mechanisms of arsenic-driven oncogenesis are not well understood. Here, we utilize experimental systems to investigate the carcinogenic and mutagenic properties of ...

Abstract	Abstract Arsenic enhances the carcinogenicity of ultraviolet radiation (UVR). However, the mechanisms of arsenic-driven oncogenesis are not well understood. Here, we utilize experimental systems to investigate the carcinogenic and mutagenic properties of co-exposure to arsenic and UVR. In vitro and in vivo exposures indicate that, by itself, arsenic is not mutagenic. However, in combination with UVR, arsenic exposure has a synergistic effect leading to an accelerated mouse skin carcinogenesis and to more than 2-fold enrichment of UVR mutational burden. Notably, mutational signature ID13, previously found only in UVR-associated human skin cancers, is observed exclusively in mouse skin tumors and cell lines jointly exposed to arsenic and UVR. This signature was not observed in any model system exposed purely to arsenic or purely to UVR, making ID13, to the best of our knowledge, the first co-exposure signature to be reported using controlled experimental conditions. Analysis of existing skin cancer genomics data reveals that only a subset of cancers harbor ID13 and these exhibit an elevated UVR mutagenesis. Our results report a unique mutational signature caused by a co-exposure to two environmental carcinogens and provide comprehensive evidence that arsenic is a potent co-mutagen and co-carcinogen of UVR.
Keywords	Biology (General) ; QH301-705.5
Subject code	616
Language	English
Publishing date	2023-12-01T00:00:00Z
Publisher	Nature Portfolio
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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