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  1. Article ; Online: Commentary on Sequence Now, Later, or Never?

    Haspel, Richard L

    Clinical chemistry

    2020  Volume 66, Issue 7, Page(s) 886–887

    Language English
    Publishing date 2020-06-17
    Publishing country England
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Comment
    ZDB-ID 80102-1
    ISSN 1530-8561 ; 0009-9147
    ISSN (online) 1530-8561
    ISSN 0009-9147
    DOI 10.1093/clinchem/hvaa056
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Examining Injustices: Transfusion Medicine and Race.

    Arya, Sumedha / Mahar, Alyson / Callum, Jeannie / Haspel, Richard L

    Transfusion medicine reviews

    2024  , Page(s) 150822

    Abstract: Race and ethnicity are sociopolitical and not biological constructs, and assertions that these population descriptors have scientific meaning has caused significant harm. A critical assessment of the transfusion medicine literature is an important aspect ...

    Abstract Race and ethnicity are sociopolitical and not biological constructs, and assertions that these population descriptors have scientific meaning has caused significant harm. A critical assessment of the transfusion medicine literature is an important aspect of promoting race-conscious as opposed to race-based medicine. Utilizing current definitions and health equity frameworks, this review will provide a critical appraisal of transfusion medicine studies at the intersection of race and healthcare disparities, with a focus on larger methodological challenges facing the transfusion medicine community. Moving forward, risk modelling accounting for upstream factors, patient input, as well as an expert consensus on how to critically conduct and evaluate this type of literature are needed. Further, when using race and ethnicity in research contexts, investigators must be aware of existing guidelines for such reporting.
    Language English
    Publishing date 2024-02-18
    Publishing country United States
    Document type Journal Article
    ZDB-ID 639107-2
    ISSN 1532-9496 ; 0887-7963
    ISSN (online) 1532-9496
    ISSN 0887-7963
    DOI 10.1016/j.tmrv.2024.150822
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Major incompatible red blood cell transfusions prior to bone marrow transplantation: Not worth the risk.

    Haspel, Richard L / McKenna, David H

    British journal of haematology

    2023  Volume 203, Issue 5, Page(s) 889–890

    MeSH term(s) Humans ; Bone Marrow Transplantation/adverse effects ; Erythrocyte Transfusion/adverse effects ; Transplantation, Homologous ; Blood Group Incompatibility ; ABO Blood-Group System ; Erythrocytes
    Chemical Substances ABO Blood-Group System
    Language English
    Publishing date 2023-09-08
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 80077-6
    ISSN 1365-2141 ; 0007-1048
    ISSN (online) 1365-2141
    ISSN 0007-1048
    DOI 10.1111/bjh.19101
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Blood Group Serology and "Race": Looking Back to Move Forward.

    Haspel, Richard L / Schneider, William H / Vege, Sunitha / Brunker, Patricia A R

    Transfusion medicine reviews

    2023  Volume 37, Issue 3, Page(s) 150749

    Abstract: Less than a decade after the discovery of the ABO antigens as a Mendelian inherited trait, blood group antigen frequencies were first used to define racial groups. This approach, known as seroanthropology, was the basis for collecting large amounts of ... ...

    Abstract Less than a decade after the discovery of the ABO antigens as a Mendelian inherited trait, blood group antigen frequencies were first used to define racial groups. This approach, known as seroanthropology, was the basis for collecting large amounts of blood group frequency data in different populations and was also sometimes used for racist purposes. Ultimately, population geneticists used these data to disprove race as a biological construct. Through understanding the history of seroanthropology, and recognizing the harms of its lingering presence, healthcare providers can better practice race-conscious, as opposed to race-based, transfusion medicine.
    MeSH term(s) Humans ; Blood Group Antigens/genetics ; Racial Groups/genetics
    Chemical Substances Blood Group Antigens
    Language English
    Publishing date 2023-07-15
    Publishing country United States
    Document type Journal Article
    ZDB-ID 639107-2
    ISSN 1532-9496 ; 0887-7963
    ISSN (online) 1532-9496
    ISSN 0887-7963
    DOI 10.1016/j.tmrv.2023.150749
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Clinical consequences of a 30-day interval between antibody identifications.

    Steele, Jasmine / Herman, Michele / Norfolk, Adam / Haspel, Richard L

    Transfusion

    2022  Volume 63, Issue 1, Page(s) 30–34

    Abstract: Background: While studies have shown that antibody detection may be delayed if an antibody identification (ABID) is not performed every 3 days, little data exist on the potential major risk of an acute hemolytic transfusion reaction (aHTR).: Study ... ...

    Abstract Background: While studies have shown that antibody detection may be delayed if an antibody identification (ABID) is not performed every 3 days, little data exist on the potential major risk of an acute hemolytic transfusion reaction (aHTR).
    Study design and methods: At our institution, if no change in the screen, or a positive crossmatch, ABIDs are performed every 30 days. Between January 1, 2015 and May 31, 2019, all new antibodies detected within 28 days of a prior transfusion were identified. Testing results and patient charts were reviewed for evidence of hemolysis. The $211 patient charge was used to determine the cost for ABIDs performed during the studied time period.
    Results: For 36 patients, a new clinically significant alloantibody was detected within 28 days of an antigen-positive transfusion. Only one of these patients had a history of prior alloimmunization and put at possible risk due to the ABID policy. For this patient, while there was less than the expected increment to an antigen-positive unit, there was no clinical or laboratory evidence of an aHTR. During this same time, 6095 ABIDs were performed, at a cost of approximately $1.29 million, and 72,665 red cell transfusions occurred.
    Conclusion: With an ABID every 30 days, only one patient, over 4.5 years, was put at potential risk for hemolysis from one transfusion (0.001% of the total units transfused during the time period). While antibody detection may be delayed, performing ABIDs every 30 days saves money and medical laboratory scientist time and should be balanced against potential patient harm.
    MeSH term(s) Humans ; Hemolysis ; Isoantibodies ; Blood Transfusion ; Blood Grouping and Crossmatching ; Erythrocyte Transfusion/methods ; Transfusion Reaction
    Chemical Substances Isoantibodies
    Language English
    Publishing date 2022-11-26
    Publishing country United States
    Document type Journal Article
    ZDB-ID 208417-x
    ISSN 1537-2995 ; 0041-1132
    ISSN (online) 1537-2995
    ISSN 0041-1132
    DOI 10.1111/trf.17203
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Development of a Validated Exam to Assess Pathologist Knowledge of Genomic Oncology.

    Haspel, Richard L / Jones, J Louise / Rizvi, Hasan / Young, Martin

    Archives of pathology & laboratory medicine

    2022  Volume 145, Issue 4, Page(s) 453–456

    Abstract: Context.—: There is a clear need to educate health professionals in genomic medicine. Pathologists, given their critical role in cancer diagnostics, must understand core concepts in genomic oncology. Although high-quality evaluation is a cornerstone of ... ...

    Abstract Context.—: There is a clear need to educate health professionals in genomic medicine. Pathologists, given their critical role in cancer diagnostics, must understand core concepts in genomic oncology. Although high-quality evaluation is a cornerstone of medical education, to our knowledge a rigorously validated genomic oncology assessment tool has not been published.
    Objective.—: To develop and validate a genomic oncology exam.
    Design.—: A previously developed exam was updated and validated using 3 approaches: pretesting/posttesting in relation to a live genomic pathology workshop; comparison of scores of individuals at a priori defined knowledge levels; and use of Rasch analysis. This last approach is used in high-stakes testing, such as licensing exams. The exam included both knowledge-based as well as skills-based questions related to the use of online genomics tools.
    Results.—: There was a significant difference in exam scores preworkshop and postworkshop (37.5% to 75%; P < .001). Individuals at a priori defined beginner, intermediate, and expert levels scored 35%, 58%, and 89%, respectively (P < .001). Rasch analysis demonstrated excellent fit and reliability and led to further exam refinement with the removal of 2 questions deemed unnecessary for assessment.
    Conclusions.—: A rigorously validated exam has now been created to assess pathologist genomic oncology knowledge and skills. The exam can be used to assess both individual learners as well as educational interventions. The exam may also be applicable to other specialties involved in genomic-based cancer care.
    MeSH term(s) Clinical Competence ; Curriculum ; Education, Medical, Graduate ; Educational Measurement ; Educational Status ; Genomics/education ; Health Knowledge, Attitudes, Practice ; Humans ; Internship and Residency ; Medical Oncology/education ; Pathologists/education ; Pathology, Molecular/education ; Surveys and Questionnaires
    Language English
    Publishing date 2022-04-01
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 194119-7
    ISSN 1543-2165 ; 0363-0153 ; 0096-8528 ; 0003-9985
    ISSN (online) 1543-2165
    ISSN 0363-0153 ; 0096-8528 ; 0003-9985
    DOI 10.5858/arpa.2020-0038-OA
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Hospital Medicine Providers' Transfusion Knowledge: A Survey Study.

    Halford, Brittne / Pinheiro, Adlin / Haspel, Richard L

    Transfusion medicine reviews

    2021  Volume 35, Issue 2, Page(s) 140–145

    Abstract: Blood transfusion is one of the most common procedures performed in the inpatient setting. Although ordering a transfusion is a component of routine practice for most hospitalists, prior literature has shown that non-transfusion medicine physicians have ... ...

    Abstract Blood transfusion is one of the most common procedures performed in the inpatient setting. Although ordering a transfusion is a component of routine practice for most hospitalists, prior literature has shown that non-transfusion medicine physicians have poor to intermediate transfusion medicine knowledge (TMK). No recent study has evaluated TMK among hospitalists, including both attending hospitalists and advanced practice providers (APPs). Using a validated exam and a truncated version of a validated survey, we obtained an initial impression of attitudes, perceived and actual TMK. A total of 183 hospital medicine providers nation-wide completed the 12-question online survey and 20 question exam, including 155 attending hospitalists and 28 APPs. The overall mean score was 52% (range 20%-85%). Forty-one percent of participants reported less than 1 hour of training in transfusion medicine. Five of the seven questions with the worst performance (<25% correct) were on transfusion reactions. Almost all respondents reported consenting a patient for blood transfusion and 60% believed that TMK was very or extremely important in order to provide appropriate care for patients. More than 80% believed that having additional transfusion medicine education would be at least moderately helpful. Although routinely consenting patients for transfusion, hospital medicine providers may have insufficient TMK particularly as it pertains to transfusion reactions. The majority of hospitalists rated TMK important to clinical practice and had an interest in additional training, thus continuing medical education has the potential to improve TMK and patient care.
    MeSH term(s) Blood Transfusion ; Hospital Medicine ; Hospitalists ; Humans ; Surveys and Questionnaires ; Transfusion Medicine
    Language English
    Publishing date 2021-04-20
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 639107-2
    ISSN 1532-9496 ; 0887-7963
    ISSN (online) 1532-9496
    ISSN 0887-7963
    DOI 10.1016/j.tmrv.2021.04.003
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Considering equity in transfusion medicine practice.

    Haspel, Richard L / Bakhtary, Sara / Miller, Yvette M / O'Brien, Kerry L / Pagano, Monica B / DeChristopher, Phillip J

    British journal of haematology

    2023  Volume 201, Issue 6, Page(s) 1248–1249

    MeSH term(s) Humans ; Transfusion Medicine ; Blood Transfusion ; Vulnerable Populations
    Language English
    Publishing date 2023-04-22
    Publishing country England
    Document type Letter
    ZDB-ID 80077-6
    ISSN 1365-2141 ; 0007-1048
    ISSN (online) 1365-2141
    ISSN 0007-1048
    DOI 10.1111/bjh.18829
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Regarding "Storage, Utilization, and Disposal of Hematopoietic Stem Cell Products in Patients with Multiple Myeloma".

    Kurbaj, Hind / Carney, Brian J / Haspel, Richard L

    Transplantation and cellular therapy

    2020  Volume 27, Issue 3, Page(s) 276–277

    MeSH term(s) Hematopoietic Stem Cells ; Humans ; Multiple Myeloma/therapy ; Transplantation, Autologous
    Language English
    Publishing date 2020-12-24
    Document type Letter ; Comment
    ZDB-ID 3062231-1
    ISSN 2666-6367
    ISSN (online) 2666-6367
    DOI 10.1016/j.jtct.2020.12.022
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: An international genomics health workforce education priorities assessment.

    Johnson, Desalyn / Dissanayake, Vajira Hw / Korf, Bruce R / Towery, Meredith / Haspel, Richard L

    Personalized medicine

    2022  Volume 19, Issue 4, Page(s) 299–306

    Abstract: Aim: ...

    Abstract Aim:
    MeSH term(s) Clinical Competence ; Curriculum ; Genomics/education ; Global Health ; Health Workforce ; Humans
    Language English
    Publishing date 2022-06-16
    Publishing country England
    Document type Journal Article
    ZDB-ID 2299146-3
    ISSN 1744-828X ; 1741-0541
    ISSN (online) 1744-828X
    ISSN 1741-0541
    DOI 10.2217/pme-2021-0094
    Database MEDical Literature Analysis and Retrieval System OnLINE

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