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  1. Book: 1 - 2 Samuel

    Cross, Frank Moore

    (Discoveries in the Judaean desert ; 17 ; Qumran cave 4 ; ; 12)

    2005  

    Title variant One two four quatre
    Author's details by Frank Moore Cross
    Series title Discoveries in the Judaean desert ; 17 ; Qumran cave 4
    ; 12
    Language English ; French ; Hebrew
    Size XIX, 267, XXVII S.
    Publisher Clarendon Press
    Publishing place Oxford
    Document type Book
    Note Text teilw. engl., teilw. franz., teilw. hebr.
    ISBN 0199249237 ; 9780199249237
    Database Former special subject collection: coastal and deep sea fishing

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  2. Book: Sir Samuel Hoare

    Cross, John Arthur

    a political biography

    1977  

    Title variant Samuel Hoare
    Author's details John Arthur Cross
    Language English
    Size XIV, 414 S., Ill.
    Document type Book
    ISBN 0224013505 ; 9780224013505
    Database Former special subject collection: coastal and deep sea fishing

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  3. Article ; Online: Challenges in Developing a Real-Time Bee-Counting Radar.

    Williams, Samuel M / Aldabashi, Nawaf / Cross, Paul / Palego, Cristiano

    Sensors (Basel, Switzerland)

    2023  Volume 23, Issue 11

    Abstract: Detailed within is an attempt to implement a real-time radar signal classification system to monitor and count bee activity at the hive entry. There is interest in keeping records of the productivity of honeybees. Activity at the entrance can be a good ... ...

    Abstract Detailed within is an attempt to implement a real-time radar signal classification system to monitor and count bee activity at the hive entry. There is interest in keeping records of the productivity of honeybees. Activity at the entrance can be a good measure of overall health and capacity, and a radar-based approach could be cheap, low power, and versatile, beyond other techniques. Fully automated systems would enable simultaneous, large-scale capturing of bee activity patterns from multiple hives, providing vital data for ecological research and business practice improvement. Data from a Doppler radar were gathered from managed beehives on a farm. Recordings were split into 0.4 s windows, and Log Area Ratios (LARs) were computed from the data. Support vector machine models were trained to recognize flight behavior from the LARs, using visual confirmation recorded by a camera. Spectrogram deep learning was also investigated using the same data. Once complete, this process would allow for removing the camera and accurately counting the events by radar-based machine learning alone. Challenging signals from more complex bee flights hindered progress. System accuracy of 70% was achieved, but clutter impacted the overall results requiring intelligent filtering to remove environmental effects from the data.
    MeSH term(s) Bees ; Animals ; Radar ; Machine Learning ; Support Vector Machine ; Ultrasonography, Doppler
    Language English
    Publishing date 2023-06-01
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2052857-7
    ISSN 1424-8220 ; 1424-8220
    ISSN (online) 1424-8220
    ISSN 1424-8220
    DOI 10.3390/s23115250
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Sudden Cardiac Death or Ventricular Arrythmia in Patients Taking Levetiracetam or Oxcarbazepine.

    Cross, Madeline R / Savitz, Samuel T / Sangaralingham, Lindsey R / So, Elson L / Ackerman, Michael J / Noseworthy, Peter A

    Neurology

    2024  Volume 102, Issue 9, Page(s) e209177

    Abstract: Background and objectives: Levetiracetam is a widely used antiseizure medication. Recent concerns have been raised regarding the potential prolongation of the QT interval by levetiracetam and increased risk of sudden cardiac death. This could have ... ...

    Abstract Background and objectives: Levetiracetam is a widely used antiseizure medication. Recent concerns have been raised regarding the potential prolongation of the QT interval by levetiracetam and increased risk of sudden cardiac death. This could have profound implications for patient safety and for prescribing practice. This study assessed the potential association of levetiracetam with cardiac outcomes related to QT interval prolongation. We compared outcomes of patients taking levetiracetam with those taking oxcarbazepine as a comparator medication that has not been associated with prolongation of the QT interval.
    Methods: The sample included patients who were newly prescribed levetiracetam or oxcarbazepine from January 31, 2010, to December 31, 2019, using administrative claims data from the OptumLabs Data Warehouse (OLDW). The analysis focused on a combined endpoint of sudden cardiac death or ventricular arrythmia, which are both linked to QT interval prolongation. We used a new user design and selected oxcarbazepine as an active comparator with levetiracetam to minimize bias. We used propensity score weighting to balance the levetiracetam and oxcarbazepine cohorts and then performed weighted Cox regressions to evaluate the association of levetiracetam with the combined endpoint.
    Results: We identified 104,655 enrollees taking levetiracetam and 39,596 enrollees taking oxcarbazepine. At baseline, enrollees taking levetiracetam were older, more likely to have diagnosed epilepsy, and more likely to have diagnosed comorbidities including hypertension, cerebrovascular disease, and coronary artery disease. In the main analysis, we found no significant difference between levetiracetam and oxcarbazepine in the rate of the combined endpoint for the Cox proportional hazards model (hazard ratio [HR] 0.79, 95% CI 0.42-1.47) or Cox regression with time-varying characteristics (HR 0.78, 95% CI 0.41-1.50).
    Discussion: When compared with oxcarbazepine, levetiracetam does not correlate with increased risk of ventricular arrythmia and sudden cardiac death. Our finding does not support the concern for cardiac risk to indicate restriction of levetiracetam use nor the requirement of cardiac monitoring when using it.
    Classification of evidence: This study provides Class II evidence that sudden cardiac death and ventricular arrythmia are not more frequent in patients older than 17 years newly prescribed levetiracetam, compared with those prescribed oxcarbazepine.
    MeSH term(s) Humans ; Levetiracetam/adverse effects ; Oxcarbazepine/adverse effects ; Anticonvulsants/adverse effects ; Death, Sudden, Cardiac/epidemiology ; Death, Sudden, Cardiac/etiology ; Arrhythmias, Cardiac/chemically induced
    Chemical Substances Levetiracetam (44YRR34555) ; Oxcarbazepine (VZI5B1W380) ; Anticonvulsants
    Language English
    Publishing date 2024-04-01
    Publishing country United States
    Document type Journal Article
    ZDB-ID 207147-2
    ISSN 1526-632X ; 0028-3878
    ISSN (online) 1526-632X
    ISSN 0028-3878
    DOI 10.1212/WNL.0000000000209177
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Decoupling body shape and mass distribution in birds and their dinosaurian ancestors.

    Macaulay, Sophie / Hoehfurtner, Tatjana / Cross, Samuel R R / Marek, Ryan D / Hutchinson, John R / Schachner, Emma R / Maher, Alice E / Bates, Karl T

    Nature communications

    2023  Volume 14, Issue 1, Page(s) 1575

    Abstract: It is accepted that non-avian theropod dinosaurs, with their long muscular tails and small forelimbs, had a centre-of-mass close to the hip, while extant birds, with their reduced tails and enlarged wings have their mass centred more cranially. ... ...

    Abstract It is accepted that non-avian theropod dinosaurs, with their long muscular tails and small forelimbs, had a centre-of-mass close to the hip, while extant birds, with their reduced tails and enlarged wings have their mass centred more cranially. Transition between these states is considered crucial to two key innovations in the avian locomotor system: crouched bipedalism and powered flight. Here we use image-based models to challenge this dichotomy. Rather than a phylogenetic distinction between 'dinosaurian' and 'avian' conditions, we find terrestrial versus volant taxa occupy distinct regions of centre-of-mass morphospace consistent with the disparate demands of terrestrial bipedalism and flight. We track this decoupled evolution of body shape and mass distribution through bird evolution, including the origin of centre-of-mass positions more advantageous for flight and major reversions coincident with terrestriality. We recover modularity in the evolution of limb proportions and centre-of-mass that suggests fully crouched bipedalism evolved after powered flight.
    MeSH term(s) Animals ; Phylogeny ; Biological Evolution ; Somatotypes ; Birds ; Dinosaurs/anatomy & histology ; Fossils
    Language English
    Publishing date 2023-03-22
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2553671-0
    ISSN 2041-1723 ; 2041-1723
    ISSN (online) 2041-1723
    ISSN 2041-1723
    DOI 10.1038/s41467-023-37317-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Vascularisation in Deep Endometriosis: A Systematic Review with Narrative Outcomes.

    Powell, Simon G / Sharma, Priyanka / Masterson, Samuel / Wyatt, James / Arshad, Ilyas / Ahmed, Shakil / Lash, Gendie / Cross, Michael / Hapangama, Dharani K

    Cells

    2023  Volume 12, Issue 9

    Abstract: Deep endometriosis (DE) is the most severe subtype of endometriosis, with the hallmark of lesions infiltrating adjacent tissue. Abnormal vascularisation has been implicated in contributing to endometriosis lesion development in general, and how ... ...

    Abstract Deep endometriosis (DE) is the most severe subtype of endometriosis, with the hallmark of lesions infiltrating adjacent tissue. Abnormal vascularisation has been implicated in contributing to endometriosis lesion development in general, and how vascularisation influences the pathogenesis of DE, in particular, is of interest. This systematic review followed the PRISMA guidelines to elucidate and examine the evidence for DE-specific vascularisation. A literature search was performed using MEDLINE, Embase, PubMed, Scopus, Cochrane CENTRAL Library and Europe PubMed Central databases. The databases were searched from inception to the 13 March 2023. A total of 15 studies with 1125 patients were included in the review. The DE lesions were highly vascularised, with a higher microvessel density (MVD) than other types of endometriotic lesions, eutopic endometrium from women with endometriosis and control tissue. Vascular endothelial growth factor, its major subtype (VEGF-A) and associated receptor (VEGFR-2) were significantly increased in the DE lesions compared to superficial endometriosis, eutopic endometrium and control tissue. Progestin therapy was associated with a significant decrease in the MVD of the DE lesions, explaining their therapeutic effect. This review comprehensively summarises the available literature, reporting abnormal vascularisation to be intimately related to the pathogenesis of DE and presents potentially preferential therapeutic targets for the medical management of DE.
    MeSH term(s) Humans ; Female ; Endometriosis/metabolism ; Vascular Endothelial Growth Factor A/metabolism ; Vascular Endothelial Growth Factors/metabolism ; Neovascularization, Pathologic/metabolism ; Endometrium/metabolism
    Chemical Substances Vascular Endothelial Growth Factor A ; Vascular Endothelial Growth Factors
    Language English
    Publishing date 2023-05-05
    Publishing country Switzerland
    Document type Systematic Review ; Journal Article ; Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 2661518-6
    ISSN 2073-4409 ; 2073-4409
    ISSN (online) 2073-4409
    ISSN 2073-4409
    DOI 10.3390/cells12091318
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Sacral insufficiency fractures are a frequent and painful consequence of pubic symphysis osteomyelitis.

    Broida, Samuel E / Kemble, Jayson P / Wahlig, Brian D / Cross, William W / Viers, Boyd R / Houdek, Matthew T

    European journal of orthopaedic surgery & traumatology : orthopedie traumatologie

    2023  Volume 34, Issue 1, Page(s) 647–652

    Abstract: Background: Pubic symphysis osteomyelitis can result from urosymphyseal fistula formation. High rates of sacropelvic insufficiency fractures have been reported in this population. The aim of this study was to describe the presentation and risk factors ... ...

    Abstract Background: Pubic symphysis osteomyelitis can result from urosymphyseal fistula formation. High rates of sacropelvic insufficiency fractures have been reported in this population. The aim of this study was to describe the presentation and risk factors for sacral insufficiency fractures (SIF) associated with surgical treatment of pubic symphysis osteomyelitis.
    Methods: A retrospective review was performed for 54 patients who underwent surgery for pubic symphysis osteomyelitis associated with a urosymphyseal fistula at a single institution from 2009 to 2022. Average age was 71 years and 53 patients (98%) were male. All patients underwent debridement or partial resection of the pubic symphysis at the time of fistula treatment. Average width of the symphyseal defect was 65 mm (range 9-122) after treatment.
    Results: Twenty patients (37%) developed SIF at a mean time of 4 months from osteomyelitis diagnosis. Rate of sacral fracture on Kaplan-Meier analysis was 31% at 6 months, 39% at 12 months, and 41% at 2 years. Eleven patients developed SIF prior to pubic debridement and 12 patients developed new or worsening of pre-existing SIF following surgery. Width of pubic resection was higher in patients who developed SIF (76 mm vs. 62 mm), but this did not meet statistical significance (p = 0.18).
    Conclusion: Sacral insufficiency fracture is a common sequela of pubic symphysis osteomyelitis. These fractures are often multifocal within the pelvis and can occur even prior to pubic resection. Pubectomy further predisposes these patients to fracture. Clinicians should maintain a high index of suspicion for these injuries in patients with symphyseal osteomyelitis.
    MeSH term(s) Humans ; Male ; Aged ; Female ; Pubic Symphysis/diagnostic imaging ; Pubic Symphysis/surgery ; Fractures, Stress/diagnostic imaging ; Fractures, Stress/etiology ; Fractures, Stress/surgery ; Fistula/complications ; Pain/complications ; Osteomyelitis/complications ; Osteomyelitis/diagnosis
    Language English
    Publishing date 2023-09-07
    Publishing country France
    Document type Journal Article
    ZDB-ID 1231084-0
    ISSN 1432-1068 ; 1633-8065 ; 0948-4817 ; 0940-3264
    ISSN (online) 1432-1068
    ISSN 1633-8065 ; 0948-4817 ; 0940-3264
    DOI 10.1007/s00590-023-03707-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Book ; Online: Navigating phase diagram complexity to guide robotic inorganic materials synthesis

    Chen, Jiadong / Cross, Samuel R. / Miara, Lincoln J. / Cho, Jeong-Ju / Wang, Yan / Sun, Wenhao

    2023  

    Abstract: Efficient synthesis recipes are needed both to streamline the manufacturing of complex materials and to accelerate the realization of theoretically predicted materials. Oftentimes the solid-state synthesis of multicomponent oxides is impeded by undesired ...

    Abstract Efficient synthesis recipes are needed both to streamline the manufacturing of complex materials and to accelerate the realization of theoretically predicted materials. Oftentimes the solid-state synthesis of multicomponent oxides is impeded by undesired byproduct phases, which can kinetically trap reactions in an incomplete non-equilibrium state. We present a thermodynamic strategy to navigate high-dimensional phase diagrams in search of precursors that circumvent low-energy competing byproducts, while maximizing the reaction energy to drive fast phase transformation kinetics. Using a robotic inorganic materials synthesis laboratory, we perform a large-scale experimental validation of our precursor selection principles. For a set of 35 target quaternary oxides with chemistries representative of intercalation battery cathodes and solid-state electrolytes, we perform 224 reactions spanning 27 elements with 28 unique precursors. Our predicted precursors frequently yield target materials with higher phase purity than when starting from traditional precursors. Robotic laboratories offer an exciting new platform for data-driven experimental science, from which we can develop new insights into materials synthesis for both robot and human chemists.
    Keywords Condensed Matter - Materials Science
    Publishing date 2023-04-03
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article ; Online: Identifying Factors for Worker Motivation in Zambia's Rural Health Facilities.

    Cross, Samuel S / Baernholdt, Dr Marianne

    Journal of health care for the poor and underserved

    2017  Volume 28, Issue 1, Page(s) 63–70

    Abstract: Background: Within Zambia there is a shortage of health workers in rural areas. This study aims to identify motivating factors for retaining rural health workers.: Methods: Sixty rural health workers completed surveys and 46 were interviewed. They ... ...

    Abstract Background: Within Zambia there is a shortage of health workers in rural areas. This study aims to identify motivating factors for retaining rural health workers.
    Methods: Sixty rural health workers completed surveys and 46 were interviewed. They rated the importance of six motivating factors and discussed these and other factors in interviews. An interview was conducted with a Government Human Resources Manager (HR Manager) to elicit contextual information.
    Results: All six factors were identified as being very important motivators, as were two additional factors. Additional career training was identified by many as the most important factor. Comparison of results and the HR Manager interview revealed that workers lacked knowledge about opportunities and that the HR manager was aware of barriers to career development.
    Conclusion: The Zambian government might better motivate and retain rural health workers by offering them any combination of identified factors, and by addressing the barriers to career development.
    MeSH term(s) Communication ; Female ; Health Facilities/standards ; Health Knowledge, Attitudes, Practice ; Health Manpower/organization & administration ; Health Personnel/psychology ; Housing/standards ; Humans ; Interviews as Topic ; Male ; Motivation ; Personnel Selection/organization & administration ; Rural Health Services/organization & administration ; Salaries and Fringe Benefits ; Staff Development/organization & administration ; Zambia
    Language English
    Publishing date 2017-02-03
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1142637-8
    ISSN 1548-6869 ; 1049-2089
    ISSN (online) 1548-6869
    ISSN 1049-2089
    DOI 10.1353/hpu.2017.0008
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Vascularisation in Deep Endometriosis

    Simon G. Powell / Priyanka Sharma / Samuel Masterson / James Wyatt / Ilyas Arshad / Shakil Ahmed / Gendie Lash / Michael Cross / Dharani K. Hapangama

    Cells, Vol 12, Iss 1318, p

    A Systematic Review with Narrative Outcomes

    2023  Volume 1318

    Abstract: Deep endometriosis (DE) is the most severe subtype of endometriosis, with the hallmark of lesions infiltrating adjacent tissue. Abnormal vascularisation has been implicated in contributing to endometriosis lesion development in general, and how ... ...

    Abstract Deep endometriosis (DE) is the most severe subtype of endometriosis, with the hallmark of lesions infiltrating adjacent tissue. Abnormal vascularisation has been implicated in contributing to endometriosis lesion development in general, and how vascularisation influences the pathogenesis of DE, in particular, is of interest. This systematic review followed the PRISMA guidelines to elucidate and examine the evidence for DE-specific vascularisation. A literature search was performed using MEDLINE, Embase, PubMed, Scopus, Cochrane CENTRAL Library and Europe PubMed Central databases. The databases were searched from inception to the 13 March 2023. A total of 15 studies with 1125 patients were included in the review. The DE lesions were highly vascularised, with a higher microvessel density (MVD) than other types of endometriotic lesions, eutopic endometrium from women with endometriosis and control tissue. Vascular endothelial growth factor, its major subtype (VEGF-A) and associated receptor (VEGFR-2) were significantly increased in the DE lesions compared to superficial endometriosis, eutopic endometrium and control tissue. Progestin therapy was associated with a significant decrease in the MVD of the DE lesions, explaining their therapeutic effect. This review comprehensively summarises the available literature, reporting abnormal vascularisation to be intimately related to the pathogenesis of DE and presents potentially preferential therapeutic targets for the medical management of DE.
    Keywords deep endometriosis ; endometriosis ; systematic review ; vascularisation ; microvessel density ; VEGF-A ; Biology (General) ; QH301-705.5
    Subject code 616
    Language English
    Publishing date 2023-05-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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