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Article ; Online: Garlic (Allium sativum) and mushroom (Agaricus bisporus) powder: Investigation of performance, immune organs and humoural and cellular immune response in broilers.

Noruzi, Hadi / Aziz-Aliabadi, Fatemeh

2024 Volume 10, Issue 2, Page(s) e31367

Abstract: Background: Alternatives to antibiotics have been suggested by banning their use in the poultry industry. Garlic and mushroom are two important phytobiotic compounds in poultry nutrition.: Objectives: This study was conducted to evaluate the effects ... ...

Abstract	Background: Alternatives to antibiotics have been suggested by banning their use in the poultry industry. Garlic and mushroom are two important phytobiotic compounds in poultry nutrition. Objectives: This study was conducted to evaluate the effects of supplementing diets with garlic and mushroom powder (MP) on growth performance, humoural and cellular immunity, and white blood cell counts of broiler chickens. Methods: Five hundred and seventy-six 1-day-old male broiler chickens (Ross 308) were assigned to 8 treatments with 6 replications (12 birds per replication) based on a completely randomized design in a factorial arrangement of 4 × 2 with 4 levels of garlic powder (GP; 0.00%, 0.50%, 1.00%, and 1.50%) and two levels of MP (0.00% and 1.00%). Results: No significant effects of GP and MP on the growth performance and cutaneous basophil hypersensitivity were observed (p > 0.05). According to the regression equation, with increasing levels of GP in the diets, the relative weight of the bursa of Fabricius and thymus increased (p < 0.05). The effect of increasing levels of GP on the Newcastle disease virus (NDV) titre was greater in the absence of MP (p < 0.05). With increasing levels of GP in the diets, the percentages of lymphocytes and heterophils to lymphocytes ratio increased and reduced, respectively (p < 0.05). Conclusions: This experiment has revealed that increasing the level of GP improved the immune response of broilers without affecting performance. The effect of increasing the level of GP on the NDV titre was more significant in the absence of MP.
MeSH term(s)	Animals ; Male ; Agaricus ; Chickens/physiology ; Garlic ; Immunity, Cellular ; Newcastle disease virus ; Powders
Chemical Substances	Powders
Language	English
Publishing date	2024-02-14
Publishing country	England
Document type	Journal Article ; Randomized Controlled Trial, Veterinary
ZDB-ID	2819409-3
ISSN	2053-1095 ; 2053-1095
ISSN (online)	2053-1095
ISSN	2053-1095
DOI	10.1002/vms3.1367
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Effects of different levels of pistachio (Pistachia vera) green hull aqueous extract on performance, intestinal morphology and antioxidant capacity in Eimeria challenged broilers.

Noruzi, Hadi / Aziz-Aliabadi, Fatemeh / Imari, Zeyad Kamal

Poultry science

2024 Volume 103, Issue 6, Page(s) 103667

Abstract: A total of 576-day-old Ross 308 broilers chicks (male) were used to evaluate the effect of various levels of pistachio green hull aqueous extract (PHE) and Eimeria challenge on the growth performance, intestinal health and antioxidant capacity. During ... ...

Abstract	A total of 576-day-old Ross 308 broilers chicks (male) were used to evaluate the effect of various levels of pistachio green hull aqueous extract (PHE) and Eimeria challenge on the growth performance, intestinal health and antioxidant capacity. During infection period (25-42 d), treatments included: 1) control + unchallenged (negative control, NC), 2) 200 ppm PHE + unchallenged, 3) 300 ppm PHE + unchallenged, 4) 400 ppm PHE + unchallenged, 5) control + challenged (positive control, PC), 6) 200 ppm PHE + challenged, 7) 300 ppm PHE + challenged and 8) 400 ppm PHE + challenged (with 6 replications for each treatment). The outcomes revealed that in the challenged birds, average body weight gain (ABW), daily weight gain (DWG), and feed conversion ratio (FCR) linearly improved with increasing the PHE levels (P < 0.05). Infected broilers had lower daily feed intake (DFI) compared to unchallenged birds (P < 0.05). Villus height (VH), villus height to crypt depth (VH: CD) ratio and villus surface area (VSA) reduced linearly (P < 0.05), while muscle layer thickness (MT) increased linearly in challenged birds (P < 0.05). The consumption of the PHE significantly reduced the excreta oocytes and duodenum and jejunum lesion scores in Eimeria-challenged broilers (P < 0.05). By increasing the PHE levels, total antioxidant capacity (TAC) and superoxide dismutase (SOD) levels increased (P < 0.05), while the Eimeria challenge reduced TAC, SOD, and glutathione peroxidase (GPx) levels (P <0.05). In general, the use of PHE in the broilers diet improved the antioxidant capacity, birds performance, but diminished the excreta oocytes and lesion scores with no negative effect on the intestinal morphology.
Language	English
Publishing date	2024-03-19
Publishing country	England
Document type	Journal Article
ZDB-ID	242586-5
ISSN	1525-3171 ; 0032-5791
ISSN (online)	1525-3171
ISSN	0032-5791
DOI	10.1016/j.psj.2024.103667
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Article ; Online: Investigating the effect of sesame meal replacement for soybean meal in diets with different levels of calcium and phytase enzyme in broiler chickens.

Aziz-Aliabadi, Fatemeh / Amirzadeh-Garou, Fariba / Hassanabadi, Ahmad / Noruzi, Hadi

Veterinary medicine and science

2024 Volume 10, Issue 2, Page(s) e1379

Abstract: Background: As a major part of the cost of broiler farms is related to their feed, breeders are looking for diets at a reasonable price. One of these affordable ingredients is sesame meal (SM), which can be used to replace soybean meal (SBM) in diets.!## ...

Abstract	Background: As a major part of the cost of broiler farms is related to their feed, breeders are looking for diets at a reasonable price. One of these affordable ingredients is sesame meal (SM), which can be used to replace soybean meal (SBM) in diets. Objectives: This study aims to investigate the effect of replacing SBM with SM in diets with different levels of calcium (Ca) and phytase (Phy) during the grower (11-24 days), finisher (25-42 days) and whole phases (11-42 days) on the growth performance, carcass characteristics and blood serum parameters of broiler chickens. Methods: A total of 600 1-day-old Ross 308 broiler male chicks were randomly dispensed to 12 dietary treatments with five replicates (10 birds per replicate) based on a completely randomized design in a factorial arrangement of 3 × 2 × 2 with 3 levels of SM (0%, 10% and 20%), 2 levels of Ca (standard (0.87% and 0.79% for grower and finisher phases, respectively) and 0.2% higher than the standard amount) and 2 levels of Phy (0 and 700 FTU/kg diet). Results: During the study, the significant effects of SM, Ca and Phy on the daily average body weight gain (DAWG) and daily feed intake (DFI) were observed, whereas for the feed conversion ratio, only the effect of SM was significant (p < 0.05). During the finisher and whole phases, the SM and Ca levels influenced the DAWG and DFI, whereas the interaction between Phy and Ca was also significant for DAWG (p < 0.05). The main effects of SM and Ca on the relative weights of breast, heart and liver were significant (p < 0.05). Application of 20% of SM significantly reduced serum Ca concentration (p < 0.05). Conclusion: Generally, the inclusion of more than 10% of SM in the broilers diet is not recommended. In addition, the use of Phy and Ca levels 0.2% higher than standard in broilers diet could improve the birds' performance.
MeSH term(s)	Animals ; Male ; 6-Phytase ; Calcium ; Chickens ; Diet/veterinary ; Flour ; Sesamum ; Weight Gain
Chemical Substances	6-Phytase (EC 3.1.3.26) ; Calcium (SY7Q814VUP)
Language	English
Publishing date	2024-02-15
Publishing country	England
Document type	Journal Article ; Randomized Controlled Trial, Veterinary
ZDB-ID	2819409-3
ISSN	2053-1095 ; 2053-1095
ISSN (online)	2053-1095
ISSN	2053-1095
DOI	10.1002/vms3.1379
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Article ; Online: Serological survey of Toxoplasma gondii infection in the one-humped camels (Camelus dromedarius) in the south of Iran.

Yektaseresht, Azadeh / Ghane, Mohsen / Atashbar, Fatemeh / Aliabadi, Jalal

Veterinary medicine and science

2023 Volume 9, Issue 5, Page(s) 2386–2389

Abstract: Background: Toxoplasmosis, an important zoonotic disease, is caused by Toxoplasma gondii. Camels are one of several host species for T. gondii parasites and play an important role in the transmission of T. gondii to humans.: Objectives: The present ... ...

Abstract	Background: Toxoplasmosis, an important zoonotic disease, is caused by Toxoplasma gondii. Camels are one of several host species for T. gondii parasites and play an important role in the transmission of T. gondii to humans. Objectives: The present study aimed to describe the seroprevalence of T. gondii in dromedary camels (Camelus dromedarius) from three provinces (Fars, Bushehr and Hormozgan), southern Iran first for this host. Methods: A total of 180 serum samples were analysed for the presence of anti-Toxoplasma IgG antibodies using the enzyme-linked immune-sorbent assay. Results: Our results showed an overall seroprevalence of T. gondii in 15% of animals. Antibodies to T. gondii were found in sera of 27 of 180 dromedary camels from Fars, Bushehr and Hormozgan provinces, southern Iran. Age or the gender of the camel did not significantly affect the seroprevalence (p > 0.05). There was no significant association between herd-level seroprevalence of T. gondii infection and abortion history, province location residence, history of animal keeping and history of contact with other animals (p > 0.05). Conclusions: The results of this study showed the presence of T. gondii antibodies among camels in Southern Iran, which could be a public health concern. According to the prevalence of T. gondii infection in camel, the implementation of control measures to reduce infection in both definitive and intermediate hosts is needed.
MeSH term(s)	Humans ; Animals ; Camelus ; Toxoplasmosis, Animal/epidemiology ; Seroepidemiologic Studies ; Iran/epidemiology ; Antibodies, Protozoan ; Toxoplasma
Chemical Substances	Antibodies, Protozoan
Language	English
Publishing date	2023-08-09
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2819409-3
ISSN	2053-1095 ; 2053-1095
ISSN (online)	2053-1095
ISSN	2053-1095
DOI	10.1002/vms3.1240
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Article ; Online: Effect of different levels of green tea (Camellia sinensis) and mulberry (Morus alba) leaves powder on performance, carcass characteristics, immune response and intestinal morphology of broiler chickens.

Aziz-Aliabadi, Fatemeh / Noruzi, Hadi / Hassanabadi, Ahmad

Veterinary medicine and science

2023 Volume 9, Issue 3, Page(s) 1281–1291

Abstract: Background: In recent years, the use of medicinal plants as an alternative to antibiotics has expanded. Plants containing medicines and antioxidants can improve the performance of poultry.: Objectives: The purpose of this study was to achieve the ... ...

Abstract	Background: In recent years, the use of medicinal plants as an alternative to antibiotics has expanded. Plants containing medicines and antioxidants can improve the performance of poultry. Objectives: The purpose of this study was to achieve the appropriate levels of green tea leaf powder (GTP) and mulberry leaf powder (MLP) in the diet, which positively affects broilers' performance. Methods: 648 one-day-old Ross 308 broiler chickens were allocated to nine dietary treatments with six replicates and each replicate containing 12 birds based on a completely randomised design (CRD) in a factorial arrangement of 3 × 3 with three levels of GTP, and three levels of MLP for 42 days. Treatments included: (1) no GTP + no MLP (control), (2) 1% GTP + no MLP, (3) 2% GTP + no MLP, (4) no GTP + 1% MLP, (5) 1% GTP + 1% MLP, (6) 2% GTP + 1% MLP, (7) no GTP + 2% MLP, (8) 1% GTP + 2% MLP and (9) 2% GTP + 2% MLP. Results: The results revealed that the effect of added powders (2%) was significant and increased daily weight gain (DWG) and reduced feed conversion ratio (FCR) compared to the control group during the grower and whole phases (p < 0.05). On 35 days, the control and 2% GTP + 2% MLP treatment had the lowest and highest antibodies titre (total and immunoglobulin G [IgG]), respectively (p < 0.05). The groups fed with 1% GTP + 1% MLP showed higher villus height (VH) compared to the control, 2% GTP + 1% MLP, 1% GTP + 2% MLP, and 2% GTP + 2% MLP groups (p < 0.05). The ratio of the villus height to crypt depth (VH: CD) in treatments 1% GTP + no MLP, 2% GTP + no MLP and 1% GTP + 1% MLP was significantly higher than the control treatment (p < 0.05). Conclusions: It was concluded that the addition of 2% GTP or MLP could improve humoral immune response and performance, and the addition of 1% GTP without MLP increased VH: CD in broilers.
MeSH term(s)	Animals ; Dietary Supplements/analysis ; Chickens ; Camellia sinensis ; Powders ; Morus ; Tea ; Animal Nutritional Physiological Phenomena ; Weight Gain ; Plant Leaves ; Immunity
Chemical Substances	Powders ; Tea
Language	English
Publishing date	2023-04-03
Publishing country	England
Document type	Journal Article
ZDB-ID	2819409-3
ISSN	2053-1095 ; 2053-1095
ISSN (online)	2053-1095
ISSN	2053-1095
DOI	10.1002/vms3.1133
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Article ; Online: Effect of Pre-Incubation of Cryopreserved Sperm with either Kisspeptin or Glutathione to Mitigate Freeze-Thaw Damage.

Kermani, Tayebeh / Hosseini, Syedeh-Fatemeh / Talaei-Khozani, Tahereh / Aliabadi, Elham

Iranian journal of medical sciences

2023 Volume 48, Issue 2, Page(s) 198–208

Abstract: Background: Sperm cryopreservation reduces sperm quality. Kisspeptin (KP) has beneficial effects on sperm functions. This study compares the effect of KP and Glutathione (GSH) on mitigating the detrimental effects of the freeze-thaw cycle on sperm.: ... ...

Abstract	Background: Sperm cryopreservation reduces sperm quality. Kisspeptin (KP) has beneficial effects on sperm functions. This study compares the effect of KP and Glutathione (GSH) on mitigating the detrimental effects of the freeze-thaw cycle on sperm. Methods: An experimental study was conducted in Birjand (Iran) during 2018-2020. Thirty normal swim-up semen samples were treated with Ham's F10 medium (negative control), 1 mM GSH (positive control), or KP (10 µM) for 30 min before freezing. The motility, acrosome reaction, capacitation, and DNA quality of the frozen-thawed sperms were assessed according to the WHO guidelines. Statistical analysis was performed using paired Results: Pre-incubation with KP significantly increased the percentage of sperm motility (34.00±6.7, P=0.003) compared to the control (20.44±7.4) and GSH-treated (31.25±12.2) aliquots. The frequency of non-capacitated spermatozoa was significantly higher in the KP-treated group (98.73%) than in the control (96.46%) and GSH-treated (96.49%) aliquots (P<0.001). The percentage of acrosome-intact spermatozoa in the KP-treated group (77.44%) was significantly higher than the control (74.3%) and GSH-treated (74.54%) groups (P<0.001). The sperm frequency with normal histone in the KP-treated group (51.86%) and with normal protamine (65.39%) was significantly higher than the controls (P=0.001 and P=0.002, respectively). The percentage of TUNEL-positive sperm was significantly lower in the KP-treated group (9.09±2.71) than both GSH-treated (11.22±2.73) and control (11.31±2.2) groups (both P=0.002). Conclusion: Pre-incubation with KP protects sperm motility and DNA integrity from the detrimental effect of the freeze-thaw cycle. KP is suitable as a pre-treatment to control sperm quality during freezing-thawing.
MeSH term(s)	Male ; Humans ; Freezing ; Kisspeptins/pharmacology ; Semen ; Sperm Motility ; Semen Preservation ; Spermatozoa ; Cryopreservation ; Glutathione/pharmacology
Chemical Substances	Kisspeptins ; Glutathione (GAN16C9B8O)
Language	English
Publishing date	2023-03-09
Publishing country	Iran
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	603872-4
ISSN	1735-3688 ; 0253-0716
ISSN (online)	1735-3688
ISSN	0253-0716
DOI	10.30476/IJMS.2022.92300.2354
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Article ; Online: Applications of palladium-catalyzed C-N cross-coupling reactions in pharmaceutical compounds.

Emadi, Reza / Bahrami Nekoo, Abbas / Molaverdi, Fatemeh / Khorsandi, Zahra / Sheibani, Reza / Sadeghi-Aliabadi, Hojjat

RSC advances

2023 Volume 13, Issue 27, Page(s) 18715–18733

Abstract: C-N cross-coupling bond formation reactions have become valuable approaches to synthesizing anilines and their derivatives, known as important chemical compounds. Recent developments in this field have focused on versatile catalysts, simple operation ... ...

Abstract	C-N cross-coupling bond formation reactions have become valuable approaches to synthesizing anilines and their derivatives, known as important chemical compounds. Recent developments in this field have focused on versatile catalysts, simple operation methods, and green reaction conditions. This review article presents an overview of C-N cross-coupling reactions in pharmaceutical compound synthesis reports. Selected examples of
Language	English
Publishing date	2023-06-20
Publishing country	England
Document type	Journal Article ; Review
ISSN	2046-2069
ISSN (online)	2046-2069
DOI	10.1039/d2ra07412e
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Article ; Online: Discovery of non-peptide GLP-1r natural agonists for enhancing coronary safety in type 2 diabetes patients.

Shakour, Neda / Hoseinpoor, Saeideh / Rajabian, Fatemeh / Azimi, Sabikeh G / Iranshahi, Mehrdad / Sadeghi-Aliabadi, Hojjat / Hadizadeh, Farzin

Journal of biomolecular structure & dynamics

2024 , Page(s) 1–18

Abstract: This study explores the computational discovery of non-peptide agonists targeting the Glucagon-Like Peptide-1 Receptor (GLP-1R) to enhance the safety of major coronary outcomes in individuals affected by Type 2 Diabetes. The objective is to identify ... ...

Abstract	This study explores the computational discovery of non-peptide agonists targeting the Glucagon-Like Peptide-1 Receptor (GLP-1R) to enhance the safety of major coronary outcomes in individuals affected by Type 2 Diabetes. The objective is to identify novel compounds that can activate the GLP-1R pathway without the limitations associated with peptide agonists. Type 2 diabetes mellitus (T2DM) is associated with an increased risk of cardiovascular disease (CVD) and mortality, which is attributed to the accumulation of fat in organs, including the heart. Glucagon-like peptide-1 receptor agonists (GLP-1RAs) are frequently used to manage T2DM and could potentially offer cardiovascular benefits. Therefore, this study examines non-peptide agonists of GLP-1R to improve coronary safety in type 2 diabetes patients. After rigorous assessments, two standout candidates were identified, with natural compound
Language	English
Publishing date	2024-01-02
Publishing country	England
Document type	Journal Article
ZDB-ID	49157-3
ISSN	1538-0254 ; 0739-1102
ISSN (online)	1538-0254
ISSN	0739-1102
DOI	10.1080/07391102.2023.2298734
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Article ; Online: Effect of Pre-Incubation of Cryopreserved Sperm with either Kisspeptin or Glutathione to Mitigate Freeze-Thaw Damage

Tayebeh Kermani / Syedeh-Fatemeh Hosseini / Tahereh Talaei-Khozani / Elham Aliabadi

Iranian Journal of Medical Sciences, Vol 48, Iss 2, Pp 198-

2023 Volume 208

Abstract	Background: Sperm cryopreservation reduces sperm quality. Kisspeptin (KP) has beneficial effects on sperm functions. This study compares the effect of KP and Glutathione (GSH) on mitigating the detrimental effects of the freeze-thaw cycle on sperm. Methods: An experimental study was conducted in Birjand (Iran) during 2018-2020. Thirty normal swim-up semen samples were treated with Ham’s F10 medium (negative control), 1 mM GSH (positive control), or KP (10 µM) for 30 min before freezing. The motility, acrosome reaction, capacitation, and DNA quality of the frozen-thawed sperms were assessed according to the WHO guidelines. Statistical analysis was performed using paired t test, one-way analysis of variance, and least significant difference.Results: Pre-incubation with KP significantly increased the percentage of sperm motility (34.00±6.7, P=0.003) compared to the control (20.44±7.4) and GSH-treated (31.25±12.2) aliquots. The frequency of non-capacitated spermatozoa was significantly higher in the KP-treated group (98.73%) than in the control (96.46%) and GSH-treated (96.49%) aliquots (P<0.001). The percentage of acrosome-intact spermatozoa in the KP-treated group (77.44%) was significantly higher than the control (74.3%) and GSH-treated (74.54%) groups (P<0.001). The sperm frequency with normal histone in the KP-treated group (51.86%) and with normal protamine (65.39%) was significantly higher than the controls (P=0.001 and P=0.002, respectively). The percentage of TUNEL-positive sperm was significantly lower in the KP-treated group (9.09±2.71) than both GSH-treated (11.22±2.73) and control (11.31±2.2) groups (both P=0.002).Conclusion: Pre-incubation with KP protects sperm motility and DNA integrity from the detrimental effect of the freeze-thaw cycle. KP is suitable as a pre-treatment to control sperm quality during freezing-thawing.
Keywords	kisspeptins ; sperm motility ; dna ; lectins ; cryopreservation ; Medicine (General) ; R5-920
Subject code	630
Language	English
Publishing date	2023-03-01T00:00:00Z
Publisher	Shiraz University of Medical Sciences
Document type	Article ; Online
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Article ; Online: Persia, the Land of Shiite Faith

Fatemeh Sadat Alavi Aliabadi / Sayed Alireza Vasei

Wawasan, Vol 6, Iss 1, Pp 55-

The Migration of Imam Ahl al-Bayt and the Encounter between Two Belief Systems in Persia

2021 Volume 66

Abstract: This article attempts to trace the fundamental role of early Persian beliefs, Zoroastrians, to the decision of Ahl al-Bayt’s choice to migrate to Persia (Iran). This research is based on the fact that there are many places for pilgrimage to imams in Iran. ...

Abstract	This article attempts to trace the fundamental role of early Persian beliefs, Zoroastrians, to the decision of Ahl al-Bayt’s choice to migrate to Persia (Iran). This research is based on the fact that there are many places for pilgrimage to imams in Iran. Specifically, this research investigates the similarity of several concepts in both religions, Zoroaster and Islam, regarding the teaching in the principle of God (Ilahiyyah), the principle of life after death (eschatology), and the principle of justice and morals of the religion embraced before Islam in Persia. Several studies have also reported on the distortions, opposition, and the consequences of encountering the two beliefs for the first time between Persian beliefs and Islamic teachings. This study employs a qualitative method with historical analysis and literature study along with relevant information of the study. This article also uses the theory of migration and identity to see the interconnectedness of religion in the migration context. The results of this study show the factors that the Persians are interested in accepting and understanding the teachings of Islam. Those are: first, the emotional closeness of beliefs and moral values between Muslims and Zoroastrians (Magi); Second, the inclusive nature of Islam; third, the absence of racial, gender, and status discrimination in Islamic teachings. The descendants of imams Ahl al-Bayt of the Prophet Muhammad SAW continued the prophet's preaching and the Imams in expanding the spread of Islamic teachings to various regions. During this expansion process, they found Iran as the most secure, and suitable region to accept the presence and teaching of Islam especially the Shiite sect. Therefore, they decided to migrate to Iran, and until now Iran is known as a Shiite country.
Keywords	ahl al-bayt ; eschatology ; god ; imam ; migration ; persia ; Ethnology. Social and cultural anthropology ; GN301-674 ; Religion (General) ; BL1-50
Subject code	290
Language	Indonesian
Publishing date	2021-08-01T00:00:00Z
Publisher	Universitas Islam Negeri Sunan Gunung Djati Bandung
Document type	Article ; Online
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