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  1. Article: Why is it so difficult to evaluate faecal microbiota transplantation as a treatment for ulcerative colitis?

    Fairhurst, Natalie Grace / Travis, Simon P L

    Intestinal research

    2018  Volume 16, Issue 2, Page(s) 209–215

    Abstract: Faecal microbiota transplantation (FMT) has recently re-emerged as a viable therapeutic option for colonic disorders. Its efficacy has been proved in the treatment ... ...

    Abstract Faecal microbiota transplantation (FMT) has recently re-emerged as a viable therapeutic option for colonic disorders. Its efficacy has been proved in the treatment of
    Language English
    Publishing date 2018-04-30
    Publishing country Korea (South)
    Document type Journal Article ; Review
    ZDB-ID 3018469-1
    ISSN 2288-1956 ; 1598-9100
    ISSN (online) 2288-1956
    ISSN 1598-9100
    DOI 10.5217/ir.2018.16.2.209
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Why is it so difficult to evaluate faecal microbiota transplantation as a treatment for ulcerative colitis?

    Natalie Grace Fairhurst / Simon P. L. Travis

    Intestinal Research, Vol 16, Iss 2, Pp 209-

    2018  Volume 215

    Abstract: Faecal microbiota transplantation (FMT) has recently re-emerged as a viable therapeutic option for colonic disorders. Its efficacy has been proved in the treatment of Clostridium difficile infection which has encouraged research into the use of FMT for ... ...

    Abstract Faecal microbiota transplantation (FMT) has recently re-emerged as a viable therapeutic option for colonic disorders. Its efficacy has been proved in the treatment of Clostridium difficile infection which has encouraged research into the use of FMT for other disorders involving gut dysbiosis, such as ulcerative colitis (UC), a chronic inflammatory disease characterized by relapsing and remitting colonic inflammation. Although the FMT protocol for C. difficile treatment is well established, there are numerous additional factors to consider when applying FMT to treat inflammatory diseases. Various studies have attempted to address these factors but technical inconsistency between reports has resulted in a failure to achieve clinically significant findings. Case reports of FMT in UC have shown favorable outcomes yet demonstrating these effects on a larger scale has proved difficult. The following review aims to explore these issues and to analyze why they may be hindering the progression of FMT therapy in UC.
    Keywords Colitis ; ulcerative ; Fecal microbiota transplantation ; Medicine ; R ; Diseases of the digestive system. Gastroenterology ; RC799-869
    Subject code 610
    Language English
    Publishing date 2018-04-01T00:00:00Z
    Publisher Korean Association for the Study of Intestinal Diseases
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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