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  1. Article ; Online: In Defense of Human Authorship: Running title: In Defense of Human Authorship.

    Gracia-Ramos, Abraham Edgar

    Archives of medical research

    2023  Volume 54, Issue 3, Page(s) 270–271

    MeSH term(s) Humans ; Authorship ; Running
    Language English
    Publishing date 2023-03-17
    Publishing country United States
    Document type Letter
    ZDB-ID 1156844-6
    ISSN 1873-5487 ; 0188-4409 ; 0188-0128
    ISSN (online) 1873-5487
    ISSN 0188-4409 ; 0188-0128
    DOI 10.1016/j.arcmed.2023.03.001
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  2. Article ; Online: Systemic lupus erythematosus after SARS-CoV-2 infection: A causal or temporal relationship?

    Gracia-Ramos, Abraham Edgar / Saavedra, Miguel Angel

    International journal of rheumatic diseases

    2023  Volume 26, Issue 12, Page(s) 2373–2376

    MeSH term(s) Humans ; COVID-19 ; SARS-CoV-2 ; Lupus Erythematosus, Systemic/complications ; Lupus Erythematosus, Systemic/diagnosis ; Lupus Erythematosus, Systemic/drug therapy ; Causality
    Language English
    Publishing date 2023-05-16
    Publishing country England
    Document type Editorial
    ZDB-ID 2426924-4
    ISSN 1756-185X ; 1756-1841
    ISSN (online) 1756-185X
    ISSN 1756-1841
    DOI 10.1111/1756-185X.14896
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    Zs.A 6098: Show issues Location:
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  3. Article ; Online: Is the ACE2 Overexpression a Risk Factor for COVID-19 Infection?

    Gracia-Ramos, Abraham Edgar

    Archives of medical research

    2020  Volume 51, Issue 4, Page(s) 345–346

    Abstract: In the recent coronavirus disease (COVID-19) outbreak, a higher proportion of patients with severe disease were found in older persons with comorbidities. This observation has been related to the use of drugs that can increase the cellular expression of ... ...

    Abstract In the recent coronavirus disease (COVID-19) outbreak, a higher proportion of patients with severe disease were found in older persons with comorbidities. This observation has been related to the use of drugs that can increase the cellular expression of angiotensin-converting enzyme 2 (ACE2) that has been recognized as target to which the virus bind to cells. Although this hypothesis is possible, it may also have other explanations which are discussed.
    MeSH term(s) Angiotensin-Converting Enzyme 2 ; Animals ; Betacoronavirus/pathogenicity ; COVID-19 ; Comorbidity ; Coronavirus Infections/enzymology ; Coronavirus Infections/pathology ; Coronavirus Infections/virology ; Humans ; Male ; Mice ; Pandemics ; Peptidyl-Dipeptidase A/metabolism ; Pneumonia, Viral/enzymology ; Pneumonia, Viral/pathology ; Pneumonia, Viral/virology ; Rats ; Rats, Sprague-Dawley ; Risk Factors ; SARS-CoV-2 ; Up-Regulation
    Chemical Substances Peptidyl-Dipeptidase A (EC 3.4.15.1) ; ACE2 protein, human (EC 3.4.17.23) ; Ace2 protein, mouse (EC 3.4.17.23) ; Ace2 protein, rat (EC 3.4.17.23) ; Angiotensin-Converting Enzyme 2 (EC 3.4.17.23)
    Keywords covid19
    Language English
    Publishing date 2020-04-04
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1156844-6
    ISSN 1873-5487 ; 0188-4409 ; 0188-0128
    ISSN (online) 1873-5487
    ISSN 0188-4409 ; 0188-0128
    DOI 10.1016/j.arcmed.2020.03.011
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  4. Article ; Online: Role of incretin-based therapy in hospitalized patients with type 2 diabetes.

    Gracia-Ramos, Abraham Edgar

    Journal of diabetes investigation

    2019  Volume 11, Issue 2, Page(s) 508–509

    Abstract: Evidence about the treatment of hospitalized type 2 diabetes patients with incretin-based therapy has emerged in the past 15 years. Based on this evidence, dipeptidyl peptidase-4 inhibitors should be considered for hospitalized patients with type 2 ... ...

    Abstract Evidence about the treatment of hospitalized type 2 diabetes patients with incretin-based therapy has emerged in the past 15 years. Based on this evidence, dipeptidyl peptidase-4 inhibitors should be considered for hospitalized patients with type 2 diabetes and an algorithm for this is proposed. In relation to use of glucagon-like peptide-1 and glucagon-like peptide-1 receptor agonist, further research is required to help define their role in the inpatient setting.
    MeSH term(s) Diabetes Mellitus, Type 2/diagnosis ; Diabetes Mellitus, Type 2/drug therapy ; Dipeptidyl-Peptidase IV Inhibitors/therapeutic use ; Disease Management ; Glucagon-Like Peptide 1/therapeutic use ; Glucagon-Like Peptide-1 Receptor/agonists ; Hospitalization ; Humans ; Incretins/therapeutic use ; Treatment Outcome
    Chemical Substances Dipeptidyl-Peptidase IV Inhibitors ; GLP1R protein, human ; Glucagon-Like Peptide-1 Receptor ; Incretins ; Glucagon-Like Peptide 1 (89750-14-1)
    Language English
    Publishing date 2019-09-17
    Publishing country Japan
    Document type Letter
    ZDB-ID 2625840-7
    ISSN 2040-1124 ; 2040-1116
    ISSN (online) 2040-1124
    ISSN 2040-1116
    DOI 10.1111/jdi.13130
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  5. Article ; Online: Is the ACE2 Overexpression a Risk Factor for COVID-19 Infection?

    Gracia-Ramos, Abraham Edgar

    Archives of Medical Research

    2020  Volume 51, Issue 4, Page(s) 345–346

    Keywords General Medicine ; covid19
    Language English
    Publisher Elsevier BV
    Publishing country us
    Document type Article ; Online
    ZDB-ID 1156844-6
    ISSN 0188-4409 ; 0188-0128
    ISSN 0188-4409 ; 0188-0128
    DOI 10.1016/j.arcmed.2020.03.011
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article: Is the ACE2 Overexpression a Risk Factor for COVID-19 Infection?

    Gracia-Ramos, Abraham Edgar

    Arch Med Res

    Abstract: In the recent coronavirus disease (COVID-19) outbreak, a higher proportion of patients with severe disease were found in older persons with comorbidities. This observation has been related to the use of drugs that can increase the cellular expression of ... ...

    Abstract In the recent coronavirus disease (COVID-19) outbreak, a higher proportion of patients with severe disease were found in older persons with comorbidities. This observation has been related to the use of drugs that can increase the cellular expression of angiotensin-converting enzyme 2 (ACE2) that has been recognized as target to which the virus bind to cells. Although this hypothesis is possible, it may also have other explanations which are discussed.
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #30825
    Database COVID19

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  7. Article: Wide complex tachycardia in a patient with COVID-19 treated with chloroquine/azithromycin.

    Gracia-Ramos, Abraham Edgar / Cortes-Ortiz, Antonio

    Oxford medical case reports

    2021  Volume 2021, Issue 1, Page(s) omaa124

    Abstract: Azithromycin and chloroquine/hydroxychloroquine are being used internationally off-label to treat patients with coronavirus disease 2019 (COVID-19) based ... ...

    Abstract Azithromycin and chloroquine/hydroxychloroquine are being used internationally off-label to treat patients with coronavirus disease 2019 (COVID-19) based on
    Language English
    Publishing date 2021-01-23
    Publishing country England
    Document type Case Reports
    ZDB-ID 2766251-2
    ISSN 2053-8855
    ISSN 2053-8855
    DOI 10.1093/omcr/omaa124
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  8. Article ; Online: Impacto de la diálisis peritoneal en la calidad de vida de adultos mayores.

    Martínez-Magaña, Josafat Francisco / Godínez-Victoria, Marycarmen / Gracia-Ramos, Abraham Edgar / García-Hernández, Ana Lilia

    Revista medica del Instituto Mexicano del Seguro Social

    2023  Volume 61, Issue Suppl 3, Page(s) S429–S436

    Abstract: Background: Nowadays elderly live longer but with more diseases and geriatric syndromes which can deteriorate their quality of life (QoL). Peritoneal dialysis (PD) is a renal replacement therapy which seeks to prolong an improve QoL; however, this is ... ...

    Title translation Peritoneal dialysis impact on quality of life in elderly.
    Abstract Background: Nowadays elderly live longer but with more diseases and geriatric syndromes which can deteriorate their quality of life (QoL). Peritoneal dialysis (PD) is a renal replacement therapy which seeks to prolong an improve QoL; however, this is uncertain in elderly. Therefore, comparing QoL before and after starting dialysis in this population may let us know if there is a benefit at this level.
    Objective: Identify the QoL that patients have before and after PD.
    Material and methods: Longitudinal, comparative, prospective cohort, before and after study. Elderly with End Stage Renal Disease in whom hospitalization for PD was indicated. QoL was measured the instrument KDQOL SF 1.3. before and after 2 months of PD. Statistical Analysis: T paired test was performed with the basal value of QoL and after. Risks with 95% confidence intervals and X2 were obtained between the basal characteristics and the dependent variable of QoL.
    Results: 21 patients. After 2 months the QoL had an increment in comparison to basal QoL, but with no statistical significance (63.47 [SD 16.63] Vs 56.83 [16.01], P= 0.22. In the 7th decade PD increased QoL by 13.01 points (P= 0.04).
    Conclusions: PD increases QoL in the 7th decade.
    MeSH term(s) Humans ; Aged ; Quality of Life ; Prospective Studies ; Peritoneal Dialysis ; Renal Dialysis ; Kidney Failure, Chronic/therapy
    Language Spanish
    Publishing date 2023-10-02
    Publishing country Mexico
    Document type English Abstract ; Journal Article
    ZDB-ID 732133-8
    ISSN 2448-5667 ; 0443-5117 ; 0484-7849
    ISSN (online) 2448-5667
    ISSN 0443-5117 ; 0484-7849
    DOI 10.5281/zenodo.8319823
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    Zs.B 2225: Show issues Location:
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  9. Article ; Online: Can the SARS-CoV-2 infection trigger systemic lupus erythematosus? A case-based review.

    Gracia-Ramos, Abraham Edgar / Saavedra-Salinas, Miguel Ángel

    Rheumatology international

    2021  Volume 41, Issue 4, Page(s) 799–809

    Abstract: Systemic lupus erythematosus (SLE) is an autoimmune and multisystemic chronic inflammatory disease that can affect various organs, including skin, joints, kidneys, lungs and the nervous system. Infectious agents have long been implicated in the ... ...

    Abstract Systemic lupus erythematosus (SLE) is an autoimmune and multisystemic chronic inflammatory disease that can affect various organs, including skin, joints, kidneys, lungs and the nervous system. Infectious agents have long been implicated in the pathogenesis of SLE. The new viral infection caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has shown that, in genetically predisposed patients could trigger the presentation or exacerbation of the autoimmune disease. We herein report a case of a 45-year-old man who presented respiratory symptoms, bilateral pleural effusion, ascites, splenomegaly, severe thrombocytopenia and renal failure with proteinuria and hematuria. SARS-CoV-2 PCR confirmed the COVID-19 diagnosis. We diagnosed the patient with SLE based on the clinical manifestations and positive immunological markers (2019 European League Against Rheumatism/American College of Rheumatology, score of 18). Glucocorticoid pulses were administered to the patient, which improved renal function. However, thrombocytopenia was also refractory to IV immunoglobulin and rituximab, so the patient underwent splenectomy. Through a systematic search of the medical literature, we retrieved two cases with newly onset SLE and five cases with previous SLE diagnosis that showed activity of the disease due to SARS-CoV-2 infection. We herein present a systemic review of these cases and discuss the clinical manifestations that could help to the diagnosis of this clinical condition.
    MeSH term(s) Autoimmunity ; COVID-19/complications ; Glucocorticoids/therapeutic use ; Humans ; Lupus Erythematosus, Systemic/diagnosis ; Lupus Erythematosus, Systemic/drug therapy ; Lupus Erythematosus, Systemic/etiology ; Male ; Middle Aged ; SARS-CoV-2
    Chemical Substances Glucocorticoids
    Language English
    Publishing date 2021-02-04
    Publishing country Germany
    Document type Case Reports ; Journal Article ; Review
    ZDB-ID 8286-7
    ISSN 1437-160X ; 0172-8172
    ISSN (online) 1437-160X
    ISSN 0172-8172
    DOI 10.1007/s00296-021-04794-7
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  10. Article: Commentary.

    Gracia-Ramos, Abraham Edgar

    Journal of neurosciences in rural practice

    2015  Volume 7, Issue Suppl 1, Page(s) S93–S94

    Language English
    Publishing date 2015-09-04
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 2601242-X
    ISSN 0976-3155 ; 0976-3147
    ISSN (online) 0976-3155
    ISSN 0976-3147
    DOI 10.4103/0976-3147.196472
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