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  1. Article ; Online: Darmmikrobiom und chronisch- entzündliche Darmerkrankung.

    Konturek, Peter C

    MMW Fortschritte der Medizin

    2022  Volume 164, Issue Suppl 7, Page(s) 12–15

    Abstract: Intestinal dysbiosis remains the focus of research into the pathogenesis of chronic inflammatory bowel disease (IBD). The potential role of gut microbiota in the development of IBD includes interaction with the host genome and immune system, as well as ... ...

    Title translation Gut microbiota and chronic inflammatory bowel disease.
    Abstract Intestinal dysbiosis remains the focus of research into the pathogenesis of chronic inflammatory bowel disease (IBD). The potential role of gut microbiota in the development of IBD includes interaction with the host genome and immune system, as well as various environmental factors, diet, drugs, industrialization, etc. Other organs are negatively affected by intestinal dysbiosis via gut-brain axis. The composition of microbiota and its metabolic activity has a significant impact on the effectiveness of anti-inflammatory therapies. Microbiome-based treatment for IBD includes the use of diet, antibiotics, pre-, pro- and synbiotics, and faecal transplantation (FMT). The development of effective therapies for IBD patients will only be possible once the interactions between the microbiota and its metabolites and the host immune system are better understood.
    MeSH term(s) Diet ; Dysbiosis/therapy ; Fecal Microbiota Transplantation/adverse effects ; Gastrointestinal Microbiome ; Humans ; Inflammatory Bowel Diseases/therapy
    Language German
    Publishing date 2022-07-13
    Publishing country Germany
    Document type Journal Article ; Review
    ZDB-ID 1478211-x
    ISSN 1613-3560 ; 1438-3276
    ISSN (online) 1613-3560
    ISSN 1438-3276
    DOI 10.1007/s15006-022-1230-3
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Wie wirkt sich COVID-19 auf die intestinale Mikrobiota aus?

    Konturek, Peter C

    MMW Fortschritte der Medizin

    2021  Volume 163, Issue Suppl 5, Page(s) 17–20

    Abstract: Background: There is a bidirectional interaction between the intestines and lungs, the so-called lung-intestinal axis.: Method: The review article reports on studies that deal with a possible influence of the intestinal microbiota on the immune ... ...

    Title translation How does COVID-19 affect intestinal microbiota?
    Abstract Background: There is a bidirectional interaction between the intestines and lungs, the so-called lung-intestinal axis.
    Method: The review article reports on studies that deal with a possible influence of the intestinal microbiota on the immune response to a SARS-CoV-2 infection.
    Results and conclusions: Studies have shown that COVID-19 is accompanied by dysbiosis that persists even after successful virus conversion (negative PCR). One study found that the severity of COVID-19 is associated with the intestinal microbiota. A dysbiosis could thus favor the so-called cytokine storm. There is indication that pre- and probiotics could boost the immune response in both the guts and lungs.
    MeSH term(s) COVID-19 ; Dysbiosis ; Gastrointestinal Microbiome ; Humans ; Intestines ; SARS-CoV-2
    Language German
    Publishing date 2021-08-10
    Publishing country Germany
    Document type Journal Article ; Review
    ZDB-ID 1478211-x
    ISSN 1613-3560 ; 1438-3276
    ISSN (online) 1613-3560
    ISSN 1438-3276
    DOI 10.1007/s15006-021-0200-5
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  3. Article ; Online: Wie das Coronavirus den Magen-Darm-Trakt angreift : Seminar / Gastromodul.

    Konturek, Peter C

    MMW Fortschritte der Medizin

    2020  Volume 162, Issue 8, Page(s) 59–60

    Title translation A gastrointestinal overview of COVID-19.
    MeSH term(s) Betacoronavirus ; COVID-19 ; Coronavirus Infections/complications ; Gastrointestinal Diseases/etiology ; Humans ; Pandemics ; Pneumonia, Viral/complications ; SARS-CoV-2
    Keywords covid19
    Language German
    Publishing date 2020-04-27
    Publishing country Germany
    Document type Journal Article ; Review
    ZDB-ID 1478211-x
    ISSN 1613-3560 ; 1438-3276
    ISSN (online) 1613-3560
    ISSN 1438-3276
    DOI 10.1007/s15006-020-0431-x
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  5. Article ; Online: Neue und bewährte Therapieansätze bei NASH.

    Konturek, Peter C

    MMW Fortschritte der Medizin

    2018  Volume 160, Issue 5, Page(s) 50–54

    Title translation Therapy of nonalcoholic steatohepatitis: the proven and the new.
    MeSH term(s) Humans ; Hypoglycemic Agents/therapeutic use ; Hypolipidemic Agents/therapeutic use ; Non-alcoholic Fatty Liver Disease/drug therapy ; Treatment Outcome
    Chemical Substances Hypoglycemic Agents ; Hypolipidemic Agents
    Language German
    Publishing date 2018-02-21
    Publishing country Germany
    Document type Journal Article ; Review
    ZDB-ID 1478211-x
    ISSN 1613-3560 ; 1438-3276
    ISSN (online) 1613-3560
    ISSN 1438-3276
    DOI 10.1007/s15006-018-0292-8
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  7. Article: Kohlenhydratmalassimilation

    Konturek, Peter C.

    Aktuelle Ernährungsmedizin

    2018  Volume 43, Issue S 01, Page(s) S24–S27

    Abstract: Kohlenhydratmalassimilationen als häufige Nahrungsmittelunverträglichkeiten spielen im klinischen Alltag eine zunehmende Rolle. Aus klinischer Sicht ist es wichtig, Intoleranzen von anderen Nahrungsmittelunverträglichkeiten, vor allem ... ...

    Abstract Kohlenhydratmalassimilationen als häufige Nahrungsmittelunverträglichkeiten spielen im klinischen Alltag eine zunehmende Rolle. Aus klinischer Sicht ist es wichtig, Intoleranzen von anderen Nahrungsmittelunverträglichkeiten, vor allem Nahrungsmittelallergien, zu differenzieren. Die Symptome der Kohlenhydratintoleranz manifestieren sich durch postprandiale Bauchschmerzen mit Übelkeit, Flatulenz und Meteorismus, gashaltige Diarrhöen und in seltenen Fällen extraintestinale Beschwerden (Fatigue, Arthralgien, Myalgien etc.). Typisch für die Kohlenhydratintoleranzen ist das Fehlen von erhöhten Entzündungsparametern, wie CrP im Blut oder Calprotectin im Stuhl. Die Kohlenhydratintoleranzen werden mit dem H 2 -Atemtest diagnostiziert. Die Therapie besteht in erster Linie darin, die verantwortlichen Zucker zu meiden. In letzter Zeit konnte eine pathophysiologische Verbindung zwischen Kohlenhydratmalabsorption und Reizdarmsyndrom festgestellt werden. Dafür ist in erster Linie die Störung der Zusammensetzung des Darmmikrobioms (Dysbiose) verantwortlich. Therapeutisch wird bei diesen Patienten eine Reduktion von Mono- und Disacchariden und Polyolen (FODMAP-Prinzip) empfohlen.
    Keywords Kohlenhydratmalassimilation ; H ; -Atemtest ; Dysbiose ; Reizdarmsyndrom ; carbohydrate malassimilation ; H ; breath test ; gut dysbiosis ; irritable bowel syndrome
    Language German
    Publishing date 2018-10-01
    Publisher © Georg Thieme Verlag KG
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 131268-6
    ISSN 1438-9916 ; 0341-0501
    ISSN (online) 1438-9916
    ISSN 0341-0501
    DOI 10.1055/a-0659-9735
    Database Thieme publisher's database

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  8. Article ; Online: Severe acute respiratory syndrome coronavirus 2 pneumonia and pulmonary embolism in a 66-year-old woman.

    Harsch, Igor A / Skiba, Marcin / Konturek, Peter C

    Polish archives of internal medicine

    2020  Volume 130, Issue 5, Page(s) 438–439

    MeSH term(s) Aged ; Betacoronavirus ; COVID-19 ; China ; Coronavirus Infections ; Female ; Humans ; Pandemics ; Pneumonia, Viral ; Pulmonary Embolism ; SARS Virus ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-05-01
    Publishing country Poland
    Document type Journal Article ; Comment
    ZDB-ID 123500-x
    ISSN 1897-9483 ; 0032-3772
    ISSN (online) 1897-9483
    ISSN 0032-3772
    DOI 10.20452/pamw.15333
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  9. Article: A case of melatonin-induced biochemical flare in a patient with primary sclerosing cholangitis with features of autoimmune hepatitis.

    Gonciarz, Maciej / Mularczyk, Aldona / Szkudłapski, Dawid / Konturek, Stanislaw J / Konturek, Peter C

    Przeglad gastroenterologiczny

    2019  Volume 14, Issue 2, Page(s) 157–159

    Language English
    Publishing date 2019-07-05
    Publishing country Poland
    Document type Journal Article
    ZDB-ID 2596134-2
    ISSN 1897-4317 ; 1895-5770
    ISSN (online) 1897-4317
    ISSN 1895-5770
    DOI 10.5114/pg.2019.85901
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  10. Article: What does a gastroenterologist need to know in the time of SARS-CoV-2 pandemia?

    Konturek, Peter Christopher / Harsch, Igor Alexander

    Wiadomosci lekarskie (Warsaw, Poland : 1960)

    2020  Volume 73, Issue 4, Page(s) 625–628

    Abstract: ... specimens. In patients obtaining FMT for recurrent C. difficile infection, recommended screening measures ...

    Abstract Coronavirus disease 2019 (COVID 19) is an emerging infectious disease caused by a novel coronavirus SARS-CoV2 that was first identified in Wuhan, China 2019 and that led to a worldwide pandemia. In addition to typical respiratory signs (dry cough, shortness of breathing), some patients may develop gastrointestinal and hepatological complications including diarrhea or acute hepatitis, respectively. Due to the close contact to the patient's secretion, the gastroenterologists are at increased risk of getting the infection. Therefore, a proper individual risk stratification before every endoscopic procedure is highly recommended. Endoscopy personnel should reduce exposure hazards by keeping a distance from the patient and using gloves, face masks, face shields and gowns. Taking into the consideration the fact that the virus proliferates in the gastrointestinal (GI) tract, special attention should be given to handling with stool specimens. In patients obtaining FMT for recurrent C. difficile infection, recommended screening measures include donor's medical history and testing for SARS-CoV-2 presence in pharyngeal and stool specimens.
    MeSH term(s) Betacoronavirus ; COVID-19 ; Clostridioides difficile ; Coronavirus Infections ; Gastroenterologists ; Humans ; Pandemics ; Pneumonia, Viral ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-07-28
    Publishing country Poland
    Document type Journal Article
    ZDB-ID 414731-5
    ISSN 0043-5147 ; 1895-0485 ; 0860-8865
    ISSN 0043-5147 ; 1895-0485 ; 0860-8865
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