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  1. Article ; Online: The opening salvo of anti-complement therapy against COVID-19.

    Campbell, Courtney M

    The Lancet Rheumatology

    2020  Volume 2, Issue 12, Page(s) e729–e730

    Keywords covid19
    Language English
    Publishing date 2020-09-28
    Publishing country England
    Document type Journal Article
    ISSN 2665-9913
    ISSN (online) 2665-9913
    DOI 10.1016/S2665-9913(20)30353-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: The opening salvo of anti-complement therapy against COVID-19

    Campbell, Courtney M

    The Lancet Rheumatology ; ISSN 2665-9913

    2020  

    Keywords covid19
    Language English
    Publisher Elsevier BV
    Publishing country us
    Document type Article ; Online
    DOI 10.1016/s2665-9913(20)30353-2
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article ; Online: Will Complement Inhibition Be the New Target in Treating COVID-19-Related Systemic Thrombosis?

    Campbell, Courtney M / Kahwash, Rami

    Circulation

    2020  Volume 141, Issue 22, Page(s) 1739–1741

    MeSH term(s) Betacoronavirus ; COVID-19 ; China ; Complement System Proteins ; Coronavirus Infections ; Humans ; Pandemics ; Pneumonia, Viral ; SARS-CoV-2 ; Thrombosis
    Chemical Substances Complement System Proteins (9007-36-7)
    Keywords covid19
    Language English
    Publishing date 2020-04-09
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 80099-5
    ISSN 1524-4539 ; 0009-7322 ; 0069-4193 ; 0065-8499
    ISSN (online) 1524-4539
    ISSN 0009-7322 ; 0069-4193 ; 0065-8499
    DOI 10.1161/CIRCULATIONAHA.120.047419
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Ui IV Zs.60: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  5. Article ; Online: Developing Therapy for Transthyretin Amyloidosis.

    Campbell, Courtney M / Zhang, Kathleen / Lenihan, Daniel J / Witteles, Ronald

    The American journal of medicine

    2022  Volume 135 Suppl 1, Page(s) S44–S48

    Abstract: Transthyretin amyloidosis (ATTR) is an under-recognized cause of cardiomyopathy and neuropathy. Until recently, there were limited therapeutic options for ATTR. However, new therapeutics, including tafamidis, patisiran, and inotersen, increase both ... ...

    Abstract Transthyretin amyloidosis (ATTR) is an under-recognized cause of cardiomyopathy and neuropathy. Until recently, there were limited therapeutic options for ATTR. However, new therapeutics, including tafamidis, patisiran, and inotersen, increase both quality and length of life in patients with ATTR. This review details the chronological development of ATTR therapies through landmark clinical trials. In addition, we discuss emerging ATTR therapies including improvements in drug delivery methods, antibodies to break down deposited amyloid fibrils, and gene editing. ATTR is a prime example of how an understanding of the pathophysiological basis of disease can lead to effective therapies. The future of ATTR therapy is bright, with every reason to believe outcomes will continue to improve.
    MeSH term(s) Amyloid Neuropathies, Familial/drug therapy ; Amyloid Neuropathies, Familial/genetics ; Cardiomyopathies/drug therapy ; Humans ; Prealbumin/genetics
    Chemical Substances Prealbumin
    Language English
    Publishing date 2022-01-22
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 80015-6
    ISSN 1555-7162 ; 1873-2178 ; 0002-9343 ; 1548-2766
    ISSN (online) 1555-7162 ; 1873-2178
    ISSN 0002-9343 ; 1548-2766
    DOI 10.1016/j.amjmed.2022.01.002
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Ua VI Zs.289: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    ab Jg. 2022: Lesesaal (EG)

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  7. Article ; Online: Will Complement Inhibition Be the New Target in Treating COVID-19–Related Systemic Thrombosis?

    Campbell, Courtney M. / Kahwash, Rami

    Circulation

    2020  Volume 141, Issue 22, Page(s) 1739–1741

    Keywords Physiology (medical) ; Cardiology and Cardiovascular Medicine ; covid19
    Language English
    Publisher Ovid Technologies (Wolters Kluwer Health)
    Publishing country us
    Document type Article ; Online
    ZDB-ID 80099-5
    ISSN 1524-4539 ; 0009-7322 ; 0069-4193 ; 0065-8499
    ISSN (online) 1524-4539
    ISSN 0009-7322 ; 0069-4193 ; 0065-8499
    DOI 10.1161/circulationaha.120.047419
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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    In stock of ZB MED Cologne/Königswinter

    Ui IV Zs.60: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  8. Article: A Call for Action to Address the Root Causes of Racial/Ethnic Health Disparities.

    Brown, Alison G M / Burt, Kate Gardner / Campbell, Elizabeth / Doby, Courtney

    Journal of the Academy of Nutrition and Dietetics

    2021  Volume 122, Issue 3, Page(s) 661–669

    MeSH term(s) Academies and Institutes ; Chronic Disease/ethnology ; Consumer Advocacy ; Ethnic and Racial Minorities ; Health Status Disparities ; Humans ; Nutrition Policy ; Social Determinants of Health ; United States
    Language English
    Publishing date 2021-12-28
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2646718-5
    ISSN 2212-2672
    ISSN 2212-2672
    DOI 10.1016/j.jand.2021.12.013
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Bonn / Germany

    Z 2828: Show issues

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  9. Article ; Online: Intensive Daily Symptom and Function Monitoring Is Feasible and Acceptable to Women Undergoing First-Line Chemotherapy for Gynecologic Cancer.

    Campbell, Grace B / Belcher, Sarah M / Lee, Young Ji / Courtney-Brooks, Madeleine / Bovbjerg, Dana H / Bizhanova, Zhadyra / Donovan, Heidi S

    Cancer nursing

    2022  Volume 45, Issue 5, Page(s) 369–377

    Abstract: Background: Women receiving chemotherapy for gynecologic cancer (GC) experience severe symptoms with associated functional changes. Understanding day-to-day symptom and function variation within and across chemotherapy treatment cycles could inform ... ...

    Abstract Background: Women receiving chemotherapy for gynecologic cancer (GC) experience severe symptoms with associated functional changes. Understanding day-to-day symptom and function variation within and across chemotherapy treatment cycles could inform improved symptom management, but such studies are rare and may be infeasible in clinical care.
    Objective: The aim of this study was to evaluate feasibility and acceptability of daily symptom monitoring combined with objective and self-reported functional assessments every 21 days during active chemotherapy for GC.
    Methods: Thirty women enrolled in a prospective observational study during first-line chemotherapy completed a daily symptom and falls diary during their entire chemotherapy treatment period. Patient-reported outcomes and objective symptom and function testing were assessed before each chemotherapy appointment. Study outcomes included accrual and attrition rates, completion of study assessments, and qualitative perceptions of study participation.
    Results: Participants were 92% White, 60% had high school or higher education, 68% were married/partnered, and 62% had stage III or IV cancer at diagnosis. The study had an 83% accrual rate, 6.6% early withdrawal rate, and 17% total attrition rate. Missing assessments for prechemotherapy patient-reported outcomes and objective assessments ranged from 27% to 35% and 35% to 47% respectively, with a general decrease across cycles. Daily diary completion rate was 83% overall. Participants rated study participation positively.
    Conclusions: Intensive daily symptom and function monitoring was feasible and acceptable to GC patients and may provide a sense of symptom controllability.
    Implications for practice: Daily symptom and function monitoring in research studies may provide patients with information to support symptom discussions with the clinical team. Future work should develop proactive symptom management interventions using personalized symptom trajectories.
    MeSH term(s) Female ; Genital Neoplasms, Female/drug therapy ; Humans ; Palliative Care ; Patient Reported Outcome Measures ; Self Report
    Language English
    Publishing date 2022-01-13
    Publishing country United States
    Document type Journal Article ; Observational Study ; Research Support, Non-U.S. Gov't
    ZDB-ID 391995-x
    ISSN 1538-9804 ; 0162-220X
    ISSN (online) 1538-9804
    ISSN 0162-220X
    DOI 10.1097/NCC.0000000000001042
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1538: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  10. Article: Estimating the natural mortality rate of saucer scallops (Ylistrum balloti) on the Queensland east coast from tag-recaptures

    Courtney, Anthony J. / Leigh, George M. / Yang, Wen-Hsi / Campbell, Matthew J. / McLennan, Mark F.

    Fisheries research. 2022 June, v. 250

    2022  

    Abstract: ... mortality (M). A total of 13,295 scallops were tagged and 526 recaptured over the 15 month-long experiment ... logistic regression model of recaptures. Estimates of M based on the Brownie model were much higher for tagged ... indicated M was higher in HBA compared to YB. Mean estimates of M for the whole fishery, derived ...

    Abstract Saucer scallops (Ylistrum balloti) were tagged and released on four occasions inside two areas closed to fishing (Hervey Bay A, HBA; and Yeppoon B, YB) on the Queensland (Australia) east coast and their subsequent recaptures over the following months were used to measure the instantaneous rate of natural mortality (M). A total of 13,295 scallops were tagged and 526 recaptured over the 15 month-long experiment (May 2018 to August 2019). Three statistical approaches were applied to the experimental design and analysis of the tagging data, based on 1) the Brownie model, 2) a modified version of the Brownie model, and 3) a binomial logistic regression model of recaptures. Estimates of M based on the Brownie model were much higher for tagged scallops that were at liberty over summer months compared to those at liberty over the winter months, possibly indicating seasonal variation. The logistic model parameter estimates indicated the proportion of recaptures differed significantly with the lunar phase at recapture, scallop size class, the number of days the scallops were at liberty and the interaction between days-at-liberty and closure. All three approaches indicated M was higher in HBA compared to YB. Mean estimates of M for the whole fishery, derived by averaging estimates from both closures, ranged from a minimum of 1.461 year–¹ for the logistic model, to 1.501 year–¹ for the Brownie model, to 1.548 year–¹ (variable recapture rate) and 1.594 year–¹ (fixed recapture rate) for the modified Brownie model. Estimates from all three approaches were higher than the previous estimate that was published over 40 years ago and possible reasons for the increase are discussed.
    Keywords coasts ; experimental design ; fisheries ; logit analysis ; models ; mortality ; research ; scallops ; seasonal variation ; summer ; Queensland
    Language English
    Dates of publication 2022-06
    Publishing place Elsevier B.V.
    Document type Article
    ZDB-ID 406532-3
    ISSN 0165-7836
    ISSN 0165-7836
    DOI 10.1016/j.fishres.2022.106273
    Database NAL-Catalogue (AGRICOLA)

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    In stock of ZB MED Bonn / Germany

    Z 3666: Show issues

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