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  1. Article ; Online: Will children reveal their secret? The coronavirus dilemma.

    Porter, George James

    The European respiratory journal

    2020  Volume 55, Issue 6

    MeSH term(s) Child ; Coronavirus ; Humans
    Keywords covid19
    Language English
    Publishing date 2020-06-25
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 639359-7
    ISSN 1399-3003 ; 0903-1936
    ISSN (online) 1399-3003
    ISSN 0903-1936
    DOI 10.1183/13993003.01382-2020
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Should lockdown be based on age rather than geography?

    Porter, George James

    Public health

    2020  Volume 196, Page(s) e1

    MeSH term(s) COVID-19 ; Geography ; Humans
    Language English
    Publishing date 2020-12-29
    Publishing country Netherlands
    Document type Letter ; Comment
    ZDB-ID 427333-3
    ISSN 1476-5616 ; 0033-3506
    ISSN (online) 1476-5616
    ISSN 0033-3506
    DOI 10.1016/j.puhe.2020.10.033
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Optimizing the Threshold to Treat Children for Latent Tuberculosis Infection: A North-East England Experience.

    Porter, George James / Whyte, Martin / Walters, Elisabetta Ghimenton / Owens, Stephen

    The Pediatric infectious disease journal

    2022  Volume 42, Issue 3, Page(s) e88–e89

    Abstract: We assessed the impact of the updated guidelines on tuberculin skin test interpretation in the North East of England. Data on 241 children screened for latent tuberculosis infection (LTBI) between January 2011 and July 2018 were analyzed; 12.4% of ... ...

    Abstract We assessed the impact of the updated guidelines on tuberculin skin test interpretation in the North East of England. Data on 241 children screened for latent tuberculosis infection (LTBI) between January 2011 and July 2018 were analyzed; 12.4% of children screened under the previous guidelines were treated for LTBI, compared to 33.3% under the new ones ( P < 0.001).
    MeSH term(s) Humans ; Child ; Latent Tuberculosis ; Tuberculin Test ; England ; Interferon-gamma Release Tests
    Language English
    Publishing date 2022-11-29
    Publishing country United States
    Document type Journal Article
    ZDB-ID 392481-6
    ISSN 1532-0987 ; 0891-3668
    ISSN (online) 1532-0987
    ISSN 0891-3668
    DOI 10.1097/INF.0000000000003786
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: A systematic review of qualitative literature on antimicrobial stewardship in Sub-Saharan Africa.

    Porter, George James / Owens, Stephen / Breckons, Matthew

    Global health research and policy

    2021  Volume 6, Issue 1, Page(s) 31

    Abstract: Background: Antibiotic resistance is a major problem in every region of the globe and Sub-Saharan Africa (SSA) is no exception. Several systematic reviews have addressed the prevalence of resistant organisms but few have examined the underlying causes ... ...

    Abstract Background: Antibiotic resistance is a major problem in every region of the globe and Sub-Saharan Africa (SSA) is no exception. Several systematic reviews have addressed the prevalence of resistant organisms but few have examined the underlying causes in this region. This systematic review of qualitative literature aims to highlight barriers and facilitators to antimicrobial stewardship in SSA.
    Methods: A literature search of Embase and MEDLINE(R) was carried out. Studies were included if they were in English, conducted in SSA, and reported qualitative data on the barriers and facilitators of antimicrobial stewardship or on attitudes towards resistance promoting behaviours. Studies were screened with a simple critical appraisal tool. Secondary constructs were extracted and coded into concepts, which were then reviewed and grouped into themes in light of the complete dataset.
    Results: The literature search yielded 169 results, of which 14 studies from 11 countries were included in the final analysis. No studies were excluded as a result of the critical appraisal. Eight concepts emerged from initial coding, which were consolidated into five major themes: ineffective regulation, health system factors, clinical governance, patient factors and lack of resources. The ineffective regulation theme highlighted the balance between tightening drugstore regulation, reducing over-the-counter sale of antibiotics, and maintaining access to medicines for rural communities. Meanwhile, health system factors explored the tension between antimicrobial stewardship and the need of pharmacy workers to maintain profitable businesses. Additionally, a lack of resources, actions by patients and the day-to-day challenges of providing healthcare were shown to directly impede antimicrobial stewardship and exacerbate other factors which promote resistance.
    Conclusion: Antibiotic resistance in SSA is a multi-faceted issue and while limited resources contribute to the problem they should be viewed in the context of other factors. We identify several contextual factors that affect resistance and stewardship that should be considered by policy makers when planning interventions. This literature base is also incomplete, with only 11 nations accounted for and many studies being confined to regions within countries, so more research is needed. Specifically, further studies on implementing stewardship interventions, successful or not, would be beneficial to inform future efforts.
    MeSH term(s) Antimicrobial Stewardship ; Delivery of Health Care ; Drug Resistance, Microbial ; Health Facilities ; Humans ; Pharmacies
    Language English
    Publishing date 2021-08-20
    Publishing country England
    Document type Journal Article ; Review ; Systematic Review
    ISSN 2397-0642
    ISSN (online) 2397-0642
    DOI 10.1186/s41256-021-00216-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: A systematic review of qualitative literature on antimicrobial stewardship in Sub-Saharan Africa

    George James Porter / Stephen Owens / Matthew Breckons

    Global Health Research and Policy, Vol 6, Iss 1, Pp 1-

    2021  Volume 11

    Abstract: Abstract Background Antibiotic resistance is a major problem in every region of the globe and Sub-Saharan Africa (SSA) is no exception. Several systematic reviews have addressed the prevalence of resistant organisms but few have examined the underlying ... ...

    Abstract Abstract Background Antibiotic resistance is a major problem in every region of the globe and Sub-Saharan Africa (SSA) is no exception. Several systematic reviews have addressed the prevalence of resistant organisms but few have examined the underlying causes in this region. This systematic review of qualitative literature aims to highlight barriers and facilitators to antimicrobial stewardship in SSA. Methods A literature search of Embase and MEDLINE(R) was carried out. Studies were included if they were in English, conducted in SSA, and reported qualitative data on the barriers and facilitators of antimicrobial stewardship or on attitudes towards resistance promoting behaviours. Studies were screened with a simple critical appraisal tool. Secondary constructs were extracted and coded into concepts, which were then reviewed and grouped into themes in light of the complete dataset. Results The literature search yielded 169 results, of which 14 studies from 11 countries were included in the final analysis. No studies were excluded as a result of the critical appraisal. Eight concepts emerged from initial coding, which were consolidated into five major themes: ineffective regulation, health system factors, clinical governance, patient factors and lack of resources. The ineffective regulation theme highlighted the balance between tightening drugstore regulation, reducing over-the-counter sale of antibiotics, and maintaining access to medicines for rural communities. Meanwhile, health system factors explored the tension between antimicrobial stewardship and the need of pharmacy workers to maintain profitable businesses. Additionally, a lack of resources, actions by patients and the day-to-day challenges of providing healthcare were shown to directly impede antimicrobial stewardship and exacerbate other factors which promote resistance. Conclusion Antibiotic resistance in SSA is a multi-faceted issue and while limited resources contribute to the problem they should be viewed in the context of other factors. We ...
    Keywords Sub-Saharan Africa ; Antibiotic resistance ; Antibiotic stewardship ; Public health ; Global health ; Qualitative synthesis ; Public aspects of medicine ; RA1-1270
    Subject code 360
    Language English
    Publishing date 2021-08-01T00:00:00Z
    Publisher BMC
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article ; Online: Reporting quality of surgical randomised controlled trials in head and neck cancer: a systematic review.

    Canagarajah, Netanya Aarabi / Porter, George James / Mitra, Kurchi / Chu, Timothy Shun Man

    European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery

    2021  Volume 278, Issue 11, Page(s) 4125–4133

    Abstract: Purpose: Randomised controlled trials (RCTs) are considered the gold standard for evaluating the efficacy of an intervention. However, previous research has shown that RCTs in several surgical specialities are poorly reported, making it difficult to ... ...

    Abstract Purpose: Randomised controlled trials (RCTs) are considered the gold standard for evaluating the efficacy of an intervention. However, previous research has shown that RCTs in several surgical specialities are poorly reported, making it difficult to ascertain if various biases have been appropriately minimised. This systematic review assesses the reporting quality of surgical head and neck cancer RCTs.
    Methods: A literature search of PubMed and Embase was performed. Papers were included if they reported RCTs which assessed a surgical technique used to treat or diagnose head and neck cancer published during or after 2011. The CONSORT 2010 checklist was used to evaluate the reporting quality of these trials.
    Results: 41 papers were included. The mean CONSORT score was 16.5/25 (66% adherence) and the scores ranged from 7.5 (30%) to 25. The most common omissions were full trial protocol (found in 14.6%), participant recruitment method (22%) and effect size with a precision estimate for all outcome measures (29.3%). The full design and implementation of the randomisation methods were reported in 6 (14.6%). Papers published in journals which endorsed CONSORT had significantly higher scores (p = 0.02) and the journal impact factor was significantly correlated with CONSORT score (p = 0.01).
    Conclusion: We have identified several pieces of information that are underreported in surgical head and neck cancer RCTs. These omissions make understanding and comparing the methodologies and conclusions of RCTs more difficult. The endorsement of CONSORT by journals improved adherence, suggesting that wider adoption of the checklist may improve reporting.
    MeSH term(s) Checklist ; Head and Neck Neoplasms/surgery ; Humans ; Randomized Controlled Trials as Topic
    Language English
    Publishing date 2021-02-19
    Publishing country Germany
    Document type Journal Article ; Review ; Systematic Review
    ZDB-ID 1017359-6
    ISSN 1434-4726 ; 0937-4477
    ISSN (online) 1434-4726
    ISSN 0937-4477
    DOI 10.1007/s00405-021-06694-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Evaluating the Current State of Epilepsy Care in the Province of Ontario.

    Van Winssen, Christine / Andrade, Andrea V / Andrade, Danielle M / Burneo, Jorge G / de Ribaupierre, Sandrine / Donner, Elizabeth / Hassan, Ayman / Ibrahim, George / Jones, Kevin C / Lomax, Lysa Boissé / Muir, Katherine / Nouri, Maryam N / Porter, Nikki / Ramachandrannair, Rajesh / Raymond, Paul / Rutka, James / Shapiro, Michelle J / Steven, David A / Swain, Darryl /
    Valiante, Taufik / Whiting, Sharon / Whitney, Robyn / Yau, Ivanna / Fantaneanu, Tadeu A

    The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques

    2024  , Page(s) 1–3

    Abstract: There are numerous challenges pertaining to epilepsy care across Ontario, including Epilepsy Monitoring Unit (EMU) bed pressures, surgical access and community supports. We sampled the current clinical, community and operational state of Ontario epilepsy ...

    Abstract There are numerous challenges pertaining to epilepsy care across Ontario, including Epilepsy Monitoring Unit (EMU) bed pressures, surgical access and community supports. We sampled the current clinical, community and operational state of Ontario epilepsy centres and community epilepsy agencies post COVID-19 pandemic. A 44-item survey was distributed to all 11 district and regional adult and paediatric Ontario epilepsy centres. Qualitative responses were collected from community epilepsy agencies. Results revealed ongoing gaps in epilepsy care across Ontario, with EMU bed pressures and labour shortages being limiting factors. A clinical network advising the Ontario Ministry of Health will improve access to epilepsy care.
    Language English
    Publishing date 2024-03-01
    Publishing country England
    Document type Journal Article
    ZDB-ID 197622-9
    ISSN 0317-1671
    ISSN 0317-1671
    DOI 10.1017/cjn.2024.30
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Health and socioeconomic resource provision for older people in South Asian countries

    Natasha Roya Matthews / George James Porter / Mathew Varghese / Nidesh Sapkota / Murad Moosa Khan / Ammu Lukose / Stella-Maria Paddick / Malathie Dissanayake / Naila Zaman Khan / Richard Walker

    Global Health Action, Vol 16, Iss

    Bangladesh, India, Nepal, Pakistan and Sri Lanka evidence from NEESAMA

    2023  Volume 1

    Abstract: Background The global population is ageing rapidly, with low- and middle-income countries (LMICs) undergoing a fast demographic transition. As the number of older adults in LMICs increases, services able to effectively address their physical and mental ... ...

    Abstract Background The global population is ageing rapidly, with low- and middle-income countries (LMICs) undergoing a fast demographic transition. As the number of older adults in LMICs increases, services able to effectively address their physical and mental health needs will be increasingly important. Objective We review the health and socioeconomic resources currently available for older people in South Asian countries, Bangladesh, India, Nepal, Pakistan and Sri Lanka, to identify gaps in available resources and assess areas for improvement. Methods We conducted a search of grey and published literature via Google Search, Compendex, EBSCO, JSTOR, Medline, Ovid, ProQuest databases, Scopus and Web of Science. Data on population demographics, human resources, health funding and social protection for older people were extracted. Local informants were consulted to supplement and verify the data. Results In the study countries, the number of health professionals with expertise in elderly care was largely unknown, with minimal postgraduate training programmes available in elderly medicine or psychiatry. Older adults are therefore cared for by general physicians, nurses and community health workers, all of whom are present in insufficient numbers per capita. Total average healthcare expenditure was 2.5–5.5% of GDP, with 48.1–72.0% of healthcare costs covered by out-of-pocket payments. Pakistan did not have a social pension; only India and Nepal offered financial assistance to people with dementia; and all countries had disproportionately low numbers of care elderly homes. Conclusions Inadequate healthcare funding, a shortage of healthcare professionals and insufficient government pension and social security schemes are significant barriers to achieving universal health coverage in LMICs. Governing bodies must expand training programmes for healthcare providers for older adults, alongside increasing social protection to improve access to those in need and to prevent catastrophic health expenditure.
    Keywords ageing ; elderly health ; mental health ; social care ; south asia ; Public aspects of medicine ; RA1-1270
    Subject code 360
    Language English
    Publishing date 2023-12-01T00:00:00Z
    Publisher Taylor & Francis Group
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article ; Online: Health and socioeconomic resource provision for older people in South Asian countries: Bangladesh, India, Nepal, Pakistan and Sri Lanka evidence from NEESAMA.

    Matthews, Natasha Roya / Porter, George James / Varghese, Mathew / Sapkota, Nidesh / Khan, Murad Moosa / Lukose, Ammu / Paddick, Stella-Maria / Dissanayake, Malathie / Khan, Naila Zaman / Walker, Richard

    Global health action

    2022  Volume 16, Issue 1, Page(s) 2110198

    Abstract: Background: The global population is ageing rapidly, with low- and middle-income countries (LMICs) undergoing a fast demographic transition. As the number of older adults in LMICs increases, services able to effectively address their physical and mental ...

    Abstract Background: The global population is ageing rapidly, with low- and middle-income countries (LMICs) undergoing a fast demographic transition. As the number of older adults in LMICs increases, services able to effectively address their physical and mental health needs will be increasingly important.
    Objective: We review the health and socioeconomic resources currently available for older people in South Asian countries, Bangladesh, India, Nepal, Pakistan and Sri Lanka, to identify gaps in available resources and assess areas for improvement.
    Methods: We conducted a search of grey and published literature via Google Search, Compendex, EBSCO, JSTOR, Medline, Ovid, ProQuest databases, Scopus and Web of Science. Data on population demographics, human resources, health funding and social protection for older people were extracted. Local informants were consulted to supplement and verify the data.
    Results: In the study countries, the number of health professionals with expertise in elderly care was largely unknown, with minimal postgraduate training programmes available in elderly medicine or psychiatry. Older adults are therefore cared for by general physicians, nurses and community health workers, all of whom are present in insufficient numbers per capita. Total average healthcare expenditure was 2.5-5.5% of GDP, with 48.1-72.0% of healthcare costs covered by out-of-pocket payments. Pakistan did not have a social pension; only India and Nepal offered financial assistance to people with dementia; and all countries had disproportionately low numbers of care elderly homes.
    Conclusions: Inadequate healthcare funding, a shortage of healthcare professionals and insufficient government pension and social security schemes are significant barriers to achieving universal health coverage in LMICs. Governing bodies must expand training programmes for healthcare providers for older adults, alongside increasing social protection to improve access to those in need and to prevent catastrophic health expenditure.
    MeSH term(s) Humans ; Aged ; Pakistan ; Bangladesh ; Sri Lanka ; Nepal ; South Asian People ; India ; Socioeconomic Factors
    Language English
    Publishing date 2022-12-20
    Publishing country United States
    Document type Journal Article ; Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 2540569-X
    ISSN 1654-9880 ; 1654-9880
    ISSN (online) 1654-9880
    ISSN 1654-9880
    DOI 10.1080/16549716.2022.2110198
    Database MEDical Literature Analysis and Retrieval System OnLINE

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