LIVIVO - Search results -

Search results

Result 1 - 10 of total 20

Search options

Article ; Online: Wingless Signaling: A Genetic Journey from Morphogenesis to Metastasis.

Bejsovec, Amy

2018 Volume 208, Issue 4, Page(s) 1311–1336

Abstract: This FlyBook chapter summarizes the history and the current state of our understanding of the Wingless signaling pathway. Wingless, the fly homolog of the mammalian Wnt oncoproteins, plays a central role in pattern generation during development. Much of ... ...

Abstract	This FlyBook chapter summarizes the history and the current state of our understanding of the Wingless signaling pathway. Wingless, the fly homolog of the mammalian Wnt oncoproteins, plays a central role in pattern generation during development. Much of what we know about the pathway was learned from genetic and molecular experiments in
MeSH term(s)	Animals ; Biomarkers ; Body Patterning/genetics ; Drosophila/embryology ; Drosophila/physiology ; Drosophila Proteins/chemistry ; Drosophila Proteins/genetics ; Drosophila Proteins/metabolism ; Evolution, Molecular ; Genetic Association Studies ; Humans ; Morphogenesis/genetics ; Phenotype ; Wnt Signaling Pathway ; Wnt1 Protein/chemistry ; Wnt1 Protein/genetics ; Wnt1 Protein/metabolism
Chemical Substances	Biomarkers ; Drosophila Proteins ; Wnt1 Protein ; wg protein, Drosophila
Language	English
Publishing date	2018-04-05
Publishing country	United States
Document type	Journal Article ; Research Support, N.I.H., Extramural ; Research Support, U.S. Gov't, Non-P.H.S. ; Review
ZDB-ID	2167-2
ISSN	1943-2631 ; 0016-6731
ISSN (online)	1943-2631
ISSN	0016-6731
DOI	10.1534/genetics.117.300157
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.B 767: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Wingless/Wnt signaling in Drosophila: the pattern and the pathway.

Bejsovec, Amy

Molecular reproduction and development

2013 Volume 80, Issue 11, Page(s) 882–894

Abstract: Wnt signaling generates pattern in all animal embryos, from flies and worms to humans, and promotes the undifferentiated, proliferative state critical for stem cells in adult tissues. Inappropriate Wnt pathway activation is the major cause of colorectal ... ...

Abstract	Wnt signaling generates pattern in all animal embryos, from flies and worms to humans, and promotes the undifferentiated, proliferative state critical for stem cells in adult tissues. Inappropriate Wnt pathway activation is the major cause of colorectal cancers, a leading cause of cancer death in humans. Although this pathway has been studied extensively for years, large gaps remain in our understanding of how it switches on and off, and how its activation changes cellular behaviors. Much of what is known about the pathway comes from genetic studies in Drosophila, where a single Wnt molecule, encoded by wingless (wg), directs an array of cell-fate decisions similar to those made by the combined activities of all 19 Wnt family members in vertebrates. Although Wg specifies fate in many tissues, including the brain, limbs, and major organs, the fly embryonic epidermis has proven to be a very powerful system for dissecting pathway activity. It is a simple, accessible tissue, with a pattern that is highly sensitive to small changes in Wg pathway activity. This review discusses what we have learned about Wnt signaling from studying mutations that disrupt epidermal pattern in the fly embryo, highlights recent advances and controversies in the field, and sets these issues in the context of questions that remain about how this essential signaling pathway functions.
MeSH term(s)	Animals ; Drosophila/embryology ; Drosophila/growth & development ; Drosophila/physiology ; Mutation ; Signal Transduction ; Wnt Proteins
Chemical Substances	Wnt Proteins
Language	English
Publishing date	2013-09-18
Publishing country	United States
Document type	Journal Article ; Research Support, N.I.H., Extramural ; Review
ZDB-ID	20321-x
ISSN	1098-2795 ; 1040-452X
ISSN (online)	1098-2795
ISSN	1040-452X
DOI	10.1002/mrd.22228
Database	MEDical Literature Analysis and Retrieval System OnLINE

Full text online

Accessible to users with ZB MED library card

In stock of ZB MED Cologne/Königswinter

Zs.A 2759: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (2.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾

Article ; Online: SoxNeuro and Shavenbaby act cooperatively to shape denticles in the embryonic epidermis of

Rizzo, Nicholas P / Bejsovec, Amy

Development (Cambridge, England)

2017 Volume 144, Issue 12, Page(s) 2248–2258

Abstract: During development, extracellular signals are integrated by cells to induce the transcriptional circuitry that controls morphogenesis. In the fly epidermis, Wingless (Wg)/Wnt signaling directs cells to produce either a distinctly shaped denticle or no ... ...

Abstract	During development, extracellular signals are integrated by cells to induce the transcriptional circuitry that controls morphogenesis. In the fly epidermis, Wingless (Wg)/Wnt signaling directs cells to produce either a distinctly shaped denticle or no denticle, resulting in a segmental pattern of denticle belts separated by smooth, or 'naked', cuticle. Naked cuticle results from Wg repression of
MeSH term(s)	Animals ; Animals, Genetically Modified ; Binding Sites ; DNA-Binding Proteins/genetics ; DNA-Binding Proteins/metabolism ; Drosophila Proteins/genetics ; Drosophila Proteins/metabolism ; Drosophila melanogaster/embryology ; Drosophila melanogaster/genetics ; Drosophila melanogaster/metabolism ; Epidermis/embryology ; Epidermis/metabolism ; Gene Expression Regulation, Developmental ; Genes, Insect ; Models, Biological ; Morphogenesis/genetics ; Morphogenesis/physiology ; Mutation ; Promoter Regions, Genetic ; SOX Transcription Factors/genetics ; SOX Transcription Factors/metabolism ; Signal Transduction ; Transcription Factors/genetics ; Transcription Factors/metabolism ; Wnt1 Protein/genetics ; Wnt1 Protein/metabolism
Chemical Substances	DNA-Binding Proteins ; Drosophila Proteins ; SOX Transcription Factors ; SoxN protein, Drosophila ; Transcription Factors ; Wnt1 Protein ; ovo protein, Drosophila ; wg protein, Drosophila
Language	English
Publishing date	2017-05-15
Publishing country	England
Document type	Journal Article
ZDB-ID	90607-4
ISSN	1477-9129 ; 0950-1991
ISSN (online)	1477-9129
ISSN	0950-1991
DOI	10.1242/dev.150169
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Ub I Zs.183: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular ab Jg. 2022: Lesesaal (EG)
Zs.MG 91: Show issues

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article: Wnt pathway activation: new relations and locations.

Bejsovec, Amy

Cell

2005 Volume 120, Issue 1, Page(s) 11–14

Abstract: Recent advances in the Wnt signaling field reveal new components, such as a G protein and an atypical receptor tyrosine kinase, and novel connections between known components. In addition, different subcellular localization of receptors may help to ... ...

Abstract	Recent advances in the Wnt signaling field reveal new components, such as a G protein and an atypical receptor tyrosine kinase, and novel connections between known components. In addition, different subcellular localization of receptors may help to explain distinctions between canonical and noncanonical Wnt pathway activity.
MeSH term(s)	Animals ; GTP-Binding Proteins/metabolism ; Intercellular Signaling Peptides and Proteins/metabolism ; Models, Biological ; Protein-Tyrosine Kinases/metabolism ; Signal Transduction/physiology ; Wnt Proteins
Chemical Substances	Intercellular Signaling Peptides and Proteins ; Wnt Proteins ; Protein-Tyrosine Kinases (EC 2.7.10.1) ; GTP-Binding Proteins (EC 3.6.1.-)
Language	English
Publishing date	2005-01-14
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	187009-9
ISSN	1097-4172 ; 0092-8674
ISSN (online)	1097-4172
ISSN	0092-8674
DOI	10.1016/j.cell.2004.12.021
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 1167: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (1.OG) ab Jg. 2022: Lesesaal (EG)
Zs.MG 58: Show issues

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: crinkled reveals a new role for Wingless signaling in Drosophila denticle formation.

Bejsovec, Amy / Chao, Anna T

Development (Cambridge, England)

2012 Volume 139, Issue 4, Page(s) 690–698

Abstract: The specification of the body plan in vertebrates and invertebrates is controlled by a variety of cell signaling pathways, but how signaling output is translated into morphogenesis is an ongoing question. Here, we describe genetic interactions between ... ...

Abstract	The specification of the body plan in vertebrates and invertebrates is controlled by a variety of cell signaling pathways, but how signaling output is translated into morphogenesis is an ongoing question. Here, we describe genetic interactions between the Wingless (Wg) signaling pathway and a nonmuscle myosin heavy chain, encoded by the crinkled (ck) locus in Drosophila. In a screen for mutations that modify wg loss-of-function phenotypes, we isolated multiple independent alleles of ck. These ck mutations dramatically alter the morphology of the hook-shaped denticles that decorate the ventral surface of the wg mutant larval cuticle. In an otherwise wild-type background, ck mutations do not significantly alter denticle morphology, suggesting a specific interaction with Wg-mediated aspects of epidermal patterning. Here, we show that changing the level of Wg activity changes the structure of actin bundles during denticle formation in ck mutants. We further find that regulation of the Wg target gene, shaven-baby (svb), and of its transcriptional targets, miniature (m) and forked (f), modulates this ck-dependent process. We conclude that Ck acts in concert with Wg targets to orchestrate the proper shaping of denticles in the Drosophila embryonic epidermis.
MeSH term(s)	Actins/metabolism ; Animals ; Drosophila Proteins/genetics ; Drosophila Proteins/metabolism ; Drosophila melanogaster/anatomy & histology ; Drosophila melanogaster/embryology ; Drosophila melanogaster/physiology ; Embryo, Nonmammalian/anatomy & histology ; Embryo, Nonmammalian/physiology ; Gene Expression Regulation, Developmental ; Humans ; Morphogenesis/physiology ; Phenotype ; Signal Transduction/physiology ; Wnt1 Protein/genetics ; Wnt1 Protein/metabolism
Chemical Substances	Actins ; Drosophila Proteins ; Wnt1 Protein ; ck protein, Drosophila ; wg protein, Drosophila
Language	English
Publishing date	2012-01-04
Publishing country	England
Document type	Journal Article ; Research Support, N.I.H., Extramural ; Research Support, U.S. Gov't, Non-P.H.S.
ZDB-ID	90607-4
ISSN	1477-9129 ; 0950-1991
ISSN (online)	1477-9129
ISSN	0950-1991
DOI	10.1242/dev.074013
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Ub I Zs.183: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular ab Jg. 2022: Lesesaal (EG)
Zs.MG 91: Show issues

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Characterization of

Cotsworth, Shawn / Jackson, Catherine J / Hallson, Graham / Fitzpatrick, Kathleen A / Syrzycka, Monika / Coulthard, Alistair B / Bejsovec, Amy / Marchetti, Marcella / Pimpinelli, Sergio / Wang, Simon J H / Camfield, Robert G / Verheyen, Esther M / Sinclair, Donald A / Honda, Barry M / Hilliker, Arthur J

Cells

2022 Volume 11, Issue 3

Abstract: ... ...

Abstract	The
MeSH term(s)	Animals ; Biosynthetic Pathways/genetics ; Drosophila melanogaster/genetics ; Drosophila melanogaster/metabolism ; Euchromatin ; Glutamine/metabolism ; Glutamine-Fructose-6-Phosphate Transaminase (Isomerizing)/genetics ; Glutamine-Fructose-6-Phosphate Transaminase (Isomerizing)/metabolism ; Hexosamines
Chemical Substances	Euchromatin ; Hexosamines ; Glutamine (0RH81L854J) ; Glutamine-Fructose-6-Phosphate Transaminase (Isomerizing) (EC 2.6.1.16)
Language	English
Publishing date	2022-01-27
Publishing country	Switzerland
Document type	Journal Article ; Research Support, Non-U.S. Gov't ; Research Support, U.S. Gov't, Non-P.H.S.
ZDB-ID	2661518-6
ISSN	2073-4409 ; 2073-4409
ISSN (online)	2073-4409
ISSN	2073-4409
DOI	10.3390/cells11030448
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Pebble/ECT2 RhoGEF negatively regulates the Wingless/Wnt signaling pathway.

Greer, Elisabeth R / Chao, Anna T / Bejsovec, Amy

Development (Cambridge, England)

2013 Volume 140, Issue 24, Page(s) 4937–4946

Abstract: Wingless (Wg)/Wnt signaling is essential for patterning invertebrate and vertebrate embryos, and inappropriate Wnt activity is associated with a variety of human cancers. Despite intensive study, Wnt pathway mechanisms are not fully understood. We have ... ...

Abstract	Wingless (Wg)/Wnt signaling is essential for patterning invertebrate and vertebrate embryos, and inappropriate Wnt activity is associated with a variety of human cancers. Despite intensive study, Wnt pathway mechanisms are not fully understood. We have discovered a new mechanism for regulating the Wnt pathway: activity of a Rho guanine nucleotide exchange factor (GEF) encoded by pebble (pbl) in Drosophila and ECT2 in humans. This RhoGEF has an essential role in cytokinesis, but also plays an unexpected, conserved role in inhibiting Wg/Wnt activity. Loss and gain of pbl function in Drosophila embryos cause pattern defects that indicate altered Wg activity. Both Pbl and ECT2 repress Wg/Wnt target gene expression in cultured Drosophila and human cells. The GEF activity is required for Wnt regulation, whereas other protein domains important for cytokinesis are not. Unlike most negative regulators of Wnt activity, Pbl/ECT2 functions downstream of Armadillo (Arm)/beta-catenin stabilization. Our results indicate GTPase regulation at a novel point in Wg/Wnt signal transduction, and provide new insight into the categorization of ECT2 as a human proto-oncogene.
MeSH term(s)	Animals ; Armadillo Domain Proteins/genetics ; Body Patterning/genetics ; Cell Line ; Drosophila Proteins/genetics ; Drosophila Proteins/metabolism ; Drosophila melanogaster/metabolism ; GTP Phosphohydrolases/metabolism ; Gene Expression Regulation, Developmental ; Guanine Nucleotide Exchange Factors/genetics ; Guanine Nucleotide Exchange Factors/metabolism ; HEK293 Cells ; Humans ; Proto-Oncogene Proteins/metabolism ; RNA Interference ; RNA, Small Interfering ; Transcription Factors/genetics ; Wnt Signaling Pathway ; Wnt1 Protein/metabolism ; beta Catenin/genetics ; rho GTP-Binding Proteins/metabolism
Chemical Substances	ARM protein, Drosophila ; Armadillo Domain Proteins ; Drosophila Proteins ; ECT2 protein, human ; Guanine Nucleotide Exchange Factors ; Pbl protein, Drosophila ; Proto-Oncogene Proteins ; RNA, Small Interfering ; Transcription Factors ; Wnt1 Protein ; beta Catenin ; wg protein, Drosophila ; GTP Phosphohydrolases (EC 3.6.1.-) ; Rho1 protein, Drosophila (EC 3.6.5.2) ; rho GTP-Binding Proteins (EC 3.6.5.2)
Language	English
Publishing date	2013-11-06
Publishing country	England
Document type	Journal Article ; Research Support, N.I.H., Extramural
ZDB-ID	90607-4
ISSN	1477-9129 ; 0950-1991
ISSN (online)	1477-9129
ISSN	0950-1991
DOI	10.1242/dev.101303
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Ub I Zs.183: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular ab Jg. 2022: Lesesaal (EG)
Zs.MG 91: Show issues

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Characterization of Gfat1 ( zeppelin ) and Gfat2 , Essential Paralogous Genes Which Encode the Enzymes That Catalyze the Rate-Limiting Step in the Hexosamine Biosynthetic Pathway in Drosophila melanogaster

Shawn Cotsworth / Catherine J. Jackson / Graham Hallson / Kathleen A. Fitzpatrick / Monika Syrzycka / Alistair B. Coulthard / Amy Bejsovec / Marcella Marchetti / Sergio Pimpinelli / Simon J. H. Wang / Robert G. Camfield / Esther M. Verheyen / Donald A. Sinclair / Barry M. Honda / Arthur J. Hilliker

Cells, Vol 11, Iss 448, p

2022 Volume 448

Abstract: The zeppelin ( zep ) locus is known for its essential role in the development of the embryonic cuticle of Drosophila melanogaster . We show here that zep encodes Gfat1 ( Glutamine: Fructose-6-Phosphate Aminotransferase 1 ... CG12449 ), the enzyme that ... ...

Abstract	The zeppelin ( zep ) locus is known for its essential role in the development of the embryonic cuticle of Drosophila melanogaster . We show here that zep encodes Gfat1 ( Glutamine: Fructose-6-Phosphate Aminotransferase 1 CG12449 ), the enzyme that catalyzes the rate-limiting step in the hexosamine biosynthesis pathway (HBP). This conserved pathway diverts 2%–5% of cellular glucose from glycolysis and is a nexus of sugar (fructose-6-phosphate), amino acid (glutamine), fatty acid [acetyl-coenzymeA (CoA)], and nucleotide/energy (UDP) metabolism. We also describe the isolation and characterization of lethal mutants in the euchromatic paralog, Gfat2 ( CG1345 ), and demonstrate that ubiquitous expression of Gfat1 + or Gfat2 + transgenes can rescue lethal mutations in either gene. Gfat1 and Gfat2 show differences in mRNA and protein expression during embryogenesis and in essential tissue-specific requirements for Gfat1 and Gfat2, suggesting a degree of functional evolutionary divergence. An evolutionary, cytogenetic analysis of the two genes in six Drosophila species revealed Gfat2 to be located within euchromatin in all six species. Gfat1 localizes to heterochromatin in three melanogaster-group species, and to euchromatin in the more distantly related species. We have also found that the pattern of flanking-gene microsynteny is highly conserved for Gfat1 and somewhat less conserved for Gfat2 .
Keywords	Gfat1 ; Gfat2 ; HBP ; hexosamine biosynthesis ; Drosophila heterochromatin ; zeppelin ; Biology (General) ; QH301-705.5
Language	English
Publishing date	2022-01-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

Full text online

Full text

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article: RacGap50C negatively regulates wingless pathway activity during Drosophila embryonic development.

Jones, Whitney M / Bejsovec, Amy

Genetics

2005 Volume 169, Issue 4, Page(s) 2075–2086

Abstract: The Wingless (Wg)/Wnt signal transduction pathway directs a variety of cell fate decisions in developing animal embryos. Despite the identification of many Wg pathway components to date, it is still not clear how these elements work together to generate ... ...

Abstract	The Wingless (Wg)/Wnt signal transduction pathway directs a variety of cell fate decisions in developing animal embryos. Despite the identification of many Wg pathway components to date, it is still not clear how these elements work together to generate cellular identities. In the ventral epidermis of Drosophila embryos, Wg specifies cells to secrete a characteristic pattern of denticles and naked cuticle that decorate the larval cuticle at the end of embryonic development. We have used the Drosophila ventral epidermis as our assay system in a series of genetic screens to identify new components involved in Wg signaling. Two mutant lines that modify wg-mediated epidermal patterning represent the first loss-of-function mutations in the RacGap50C gene. These mutations on their own cause increased stabilization of Armadillo and cuticle pattern disruptions that include replacement of ventral denticles with naked cuticle, which suggests that the mutant embryos suffer from ectopic Wg pathway activation. In addition, RacGap50C mutations interact genetically with naked cuticle and Axin, known negative regulators of the Wg pathway. These phenotypes suggest that the RacGap50C gene product participates in the negative regulation of Wg pathway activity.
MeSH term(s)	Alleles ; Animals ; Armadillo Domain Proteins ; Axin Protein ; Body Patterning ; Crosses, Genetic ; Drosophila Proteins/biosynthesis ; Drosophila Proteins/chemistry ; Drosophila Proteins/metabolism ; Epidermis/embryology ; Epidermis/metabolism ; GTPase-Activating Proteins/chemistry ; GTPase-Activating Proteins/metabolism ; GTPase-Activating Proteins/physiology ; Gene Expression Regulation, Developmental ; Green Fluorescent Proteins/metabolism ; In Situ Hybridization ; Mutation ; Phenotype ; Protein Binding ; Proto-Oncogene Proteins/biosynthesis ; RNA/metabolism ; Repressor Proteins/genetics ; Signal Transduction ; Trans-Activators/biosynthesis ; Transgenes ; Wings, Animal/embryology ; Wnt1 Protein
Chemical Substances	Armadillo Domain Proteins ; Axin Protein ; Drosophila Proteins ; GTPase-Activating Proteins ; Proto-Oncogene Proteins ; Repressor Proteins ; Trans-Activators ; Wnt1 Protein ; tum protein, Drosophila ; wg protein, Drosophila ; Green Fluorescent Proteins (147336-22-9) ; RNA (63231-63-0)
Language	English
Publishing date	2005-02-03
Publishing country	United States
Document type	Journal Article ; Research Support, N.I.H., Extramural ; Research Support, U.S. Gov't, P.H.S.
ZDB-ID	2167-2
ISSN	1943-2631 ; 0016-6731
ISSN (online)	1943-2631
ISSN	0016-6731
DOI	10.1534/genetics.104.039735
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.B 767: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article: Wingless signaling: an axin to grind.

Jones, Whitney M / Bejsovec, Amy

Current biology : CB

2003 Volume 13, Issue 12, Page(s) R479–81

Abstract: Negative regulation of Wingless/Wnt signaling plays an important role in embryonic patterning and is also needed for tumor suppression in adult tissues. New findings in Drosophila reveal a novel mechanism for down-regulating the activity of the Wingless/ ... ...

Abstract	Negative regulation of Wingless/Wnt signaling plays an important role in embryonic patterning and is also needed for tumor suppression in adult tissues. New findings in Drosophila reveal a novel mechanism for down-regulating the activity of the Wingless/Wnt pathway.
MeSH term(s)	Animals ; Down-Regulation ; Drosophila/embryology ; Drosophila Proteins/physiology ; Morphogenesis ; Proto-Oncogene Proteins/physiology ; Signal Transduction ; Wnt1 Protein
Chemical Substances	Drosophila Proteins ; Proto-Oncogene Proteins ; Wnt1 Protein ; wg protein, Drosophila
Language	English
Publishing date	2003-06-17
Publishing country	England
Document type	Journal Article ; Review
ZDB-ID	1071731-6
ISSN	1879-0445 ; 0960-9822
ISSN (online)	1879-0445
ISSN	0960-9822
DOI	10.1016/s0960-9822(03)00407-x
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 3208: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (2.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

To top

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

Full text online

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

Full text online

More links

Kategorien

Inter-library loan at ZB MED

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito