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  1. Article: Responsibility and Laboratory Animal Research Governance.

    McLeod, Carmen / Hartley, Sarah

    Science, technology & human values

    2017  Volume 43, Issue 4, Page(s) 723–741

    Abstract: The use of animals in experiments and research remains highly contentious. Laboratory animal research governance provides guidance and regulatory frameworks to oversee the use and welfare of laboratory animals and relies heavily on the replacement, ... ...

    Abstract The use of animals in experiments and research remains highly contentious. Laboratory animal research governance provides guidance and regulatory frameworks to oversee the use and welfare of laboratory animals and relies heavily on the replacement, reduction, and refinement (3Rs) principles to demonstrate responsibility. However, the application of the 3Rs is criticized for being too narrow in focus and closing down societal concerns and political questions about the purpose of animal laboratory research. These critiques challenge the legitimacy of responsibility in laboratory animal research governance and call for new approaches. With the advent of the "Responsible Research and Innovation" (RRI) agenda, we investigate whether the notion of responsibility in the controversial area of animal research governance could be enhanced by examining the 3Rs through RRI. Our analysis reveals RRI has the potential to helpfully augment the 3Rs in three key ways: recognizing the need to include a broader range of experts and publics in animal research governance; emphasizing the importance for animal research scientists of taking societal, and not just role, responsibilities into account; and acknowledging the political questions animal research raises.
    Language English
    Publishing date 2017-09-01
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2021122-3
    ISSN 1552-8251 ; 0162-2439
    ISSN (online) 1552-8251
    ISSN 0162-2439
    DOI 10.1177/0162243917727866
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Synthetic biology, metaphors and responsibility.

    McLeod, Carmen / Nerlich, Brigitte

    Life sciences, society and policy

    2017  Volume 13, Issue 1, Page(s) 13

    Abstract: Metaphors are not just decorative rhetorical devices that make speech pretty. They are fundamental tools for thinking about the world and acting on the world. The language we use to make a better world matters; words matter; metaphors matter. Words have ... ...

    Abstract Metaphors are not just decorative rhetorical devices that make speech pretty. They are fundamental tools for thinking about the world and acting on the world. The language we use to make a better world matters; words matter; metaphors matter. Words have consequences - ethical, social and legal ones, as well as political and economic ones. They need to be used 'responsibly'. They also need to be studied carefully - this is what we want to do through this editorial and the related thematic collection. In the context of synthetic biology, natural and social scientists have become increasingly interested in metaphors, a wave of interest that we want to exploit and amplify. We want to build on emerging articles and books on synthetic biology, metaphors of life and the ethical and moral implications of such metaphors. This editorial provides a brief introduction to synthetic biology and responsible innovation, as well as a comprehensive review of literature on the social, cultural and ethical impacts of metaphor use in genomics and synthetic biology. Our aim is to stimulate an interdisciplinary and international discussion on the impact that metaphors can have on science, policy and publics in the context of synthetic biology.
    MeSH term(s) Biology ; Genomics ; Humans ; Language ; Metaphor ; Molecular Biology ; Social Behavior ; Social Responsibility ; Synthetic Biology ; Systems Biology ; Thinking
    Language English
    Publishing date 2017-08-29
    Publishing country England
    Document type Journal Article
    ZDB-ID 2711762-5
    ISSN 2195-7819 ; 2195-7819
    ISSN (online) 2195-7819
    ISSN 2195-7819
    DOI 10.1186/s40504-017-0061-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: The Sustainable Path to a Circular Bioeconomy.

    Hadley Kershaw, Eleanor / Hartley, Sarah / McLeod, Carmen / Polson, Penelope

    Trends in biotechnology

    2020  Volume 39, Issue 6, Page(s) 542–545

    Abstract: Circular bioeconomy is gaining prominence in academic, policy, and industry contexts, linking circular economy and bioeconomy agendas in service of sustainability. However, it is at risk of developing in narrow, unsustainable ways. A sustainable path to ... ...

    Abstract Circular bioeconomy is gaining prominence in academic, policy, and industry contexts, linking circular economy and bioeconomy agendas in service of sustainability. However, it is at risk of developing in narrow, unsustainable ways. A sustainable path to circular bioeconomies must embrace diverse expert and stakeholder input, multiple solutions, and noneconomic value.
    MeSH term(s) Biotechnology/economics ; Industry/economics ; Policy ; Sustainable Development/economics
    Language English
    Publishing date 2020-11-25
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 47474-5
    ISSN 1879-3096 ; 0167-7799
    ISSN (online) 1879-3096
    ISSN 0167-7799
    DOI 10.1016/j.tibtech.2020.10.015
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: The dilemma of raising awareness "responsibly": The need to discuss controversial research with the public raises a conundrum for scientists: when is the right time to start public debates?

    Nerlich, Brigitte / McLeod, Carmen

    EMBO reports

    2016  Volume 17, Issue 4, Page(s) 481–485

    MeSH term(s) Climate Change ; Ethics, Research ; Humans ; Inventions/ethics ; Public Opinion ; Research ; Synthetic Biology/education ; Synthetic Biology/ethics
    Language English
    Publishing date 2016-03-17
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2020896-0
    ISSN 1469-3178 ; 1469-221X
    ISSN (online) 1469-3178
    ISSN 1469-221X
    DOI 10.15252/embr.201541853
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Risk in synthetic biology-views from the lab: Early career scientists' concerns about synthetic biology open up new perspectives on risk and responsibility in research.

    McLeod, Carmen / de Saille, Stevienna / Nerlich, Brigitte

    EMBO reports

    2018  Volume 19, Issue 7

    MeSH term(s) Biotechnology/trends ; Communication ; Humans ; Research/trends ; Research Personnel/psychology ; Synthetic Biology/trends ; United Kingdom
    Language English
    Publishing date 2018-06-01
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2020896-0
    ISSN 1469-3178 ; 1469-221X
    ISSN (online) 1469-3178
    ISSN 1469-221X
    DOI 10.15252/embr.201845958
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: The Sustainable Path to a Circular Bioeconomy

    Hadley Kershaw, Eleanor / Hartley, Sarah / McLeod, Carmen / Polson, Penelope

    Trends in biotechnology. 2021 June, v. 39, no. 6

    2021  

    Abstract: Circular bioeconomy is gaining prominence in academic, policy, and industry contexts, linking circular economy and bioeconomy agendas in service of sustainability. However, it is at risk of developing in narrow, unsustainable ways. A sustainable path to ... ...

    Abstract Circular bioeconomy is gaining prominence in academic, policy, and industry contexts, linking circular economy and bioeconomy agendas in service of sustainability. However, it is at risk of developing in narrow, unsustainable ways. A sustainable path to circular bioeconomies must embrace diverse expert and stakeholder input, multiple solutions, and noneconomic value.
    Keywords bioeconomics ; biotechnology ; circular economy ; industry ; issues and policy ; risk ; stakeholders
    Language English
    Dates of publication 2021-06
    Size p. 542-545.
    Publishing place Elsevier Ltd
    Document type Article
    Note NAL-AP-2-clean
    ZDB-ID 47474-5
    ISSN 1879-3096 ; 0167-7799
    ISSN (online) 1879-3096
    ISSN 0167-7799
    DOI 10.1016/j.tibtech.2020.10.015
    Database NAL-Catalogue (AGRICOLA)

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  7. Article ; Online: Nanometer-Scale Lateral p-n Junctions in Graphene/α-RuCl

    Rizzo, Daniel J / Shabani, Sara / Jessen, Bjarke S / Zhang, Jin / McLeod, Alexander S / Rubio-Verdú, Carmen / Ruta, Francesco L / Cothrine, Matthew / Yan, Jiaqiang / Mandrus, David G / Nagler, Stephen E / Rubio, Angel / Hone, James C / Dean, Cory R / Pasupathy, Abhay N / Basov, D N

    Nano letters

    2022  Volume 22, Issue 5, Page(s) 1946–1953

    Abstract: The ability to create nanometer-scale lateral p-n junctions is essential for the next generation of two-dimensional (2D) devices. Using the charge-transfer heterostructure graphene/α- ... ...

    Abstract The ability to create nanometer-scale lateral p-n junctions is essential for the next generation of two-dimensional (2D) devices. Using the charge-transfer heterostructure graphene/α-RuCl
    Language English
    Publishing date 2022-02-28
    Publishing country United States
    Document type Journal Article
    ISSN 1530-6992
    ISSN (online) 1530-6992
    DOI 10.1021/acs.nanolett.1c04579
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Working with bacteria and putting bacteria to work: The biopolitics of synthetic biology for energy in the United Kingdom.

    McLeod, Carmen / Nerlich, Brigitte / Mohr, Alison

    Energy research & social science

    2017  Volume 30, Page(s) 35–42

    Abstract: The UK government has made significant investment into so called 'fourth-generation' biofuel technologies. These biofuels are based on engineering the metabolic pathways of bacteria in order to create products compatible with existing infrastructure. ... ...

    Abstract The UK government has made significant investment into so called 'fourth-generation' biofuel technologies. These biofuels are based on engineering the metabolic pathways of bacteria in order to create products compatible with existing infrastructure. Bacteria play an important role in what is promoted as a potentially new biological industrial revolution, which could address some of the negative environmental legacies of the last. This article presents results from ethnographic research with synthetic biologists who are challenged with balancing the curiosity-driven and intrinsically fulfilling scientific task of working with bacteria, alongside the policy-driven task of putting bacteria to work for extrinsic economic gains. In addition, the scientists also have to balance these demands with a new research governance framework, Responsible Research and Innovation, which envisions technoscientific innovation will be responsive to societal concerns and work in collaboration with stakeholders and members of the public. Major themes emerging from the ethnographic research revolve around stewardship, care, responsibility and agency. An overall conflict surfaces between individual agents assuming responsibility for 'stewarding' bacteria, against funding systems and structures imposing responsibility for economic growth. We discuss these findings against the theoretical backdrop of a new concept of 'energopolitics' and an anthropology of ethics and responsibility.
    Language English
    Publishing date 2017-01-21
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2763226-X
    ISSN 2214-6296
    ISSN 2214-6296
    DOI 10.1016/j.erss.2017.06.017
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: The microbiome and its publics: A participatory approach for engaging publics with the microbiome and its implications for health and hygiene.

    Hodgetts, Timothy / Grenyer, Richard / Greenhough, Beth / McLeod, Carmen / Dwyer, Andrew / Lorimer, Jamie

    EMBO reports

    2018  Volume 19, Issue 6

    MeSH term(s) Community Participation ; Humans ; Hygiene Hypothesis ; Metagenomics ; Microbiota/genetics ; Public Health ; Stakeholder Participation
    Language English
    Publishing date 2018-05-18
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2020896-0
    ISSN 1469-3178 ; 1469-221X
    ISSN (online) 1469-3178
    ISSN 1469-221X
    DOI 10.15252/embr.201845786
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Opening up animal research and science-society relations? A thematic analysis of transparency discourses in the United Kingdom.

    McLeod, Carmen / Hobson-West, Pru

    Public understanding of science (Bristol, England)

    2015  Volume 25, Issue 7, Page(s) 791–806

    Abstract: The use of animals in scientific research represents an interesting case to consider in the context of the contemporary preoccupation with transparency and openness in science and governance. In the United Kingdom, organisations critical of animal ... ...

    Abstract The use of animals in scientific research represents an interesting case to consider in the context of the contemporary preoccupation with transparency and openness in science and governance. In the United Kingdom, organisations critical of animal research have long called for more openness. More recently, organisations involved in animal research also seem to be embracing transparency discourses. This article provides a detailed analysis of publically available documents from animal protection groups, the animal research community and government/research funders. Our aim is to explore the similarities and differences in the way transparency is constructed and to identify what more openness is expected to achieve. In contrast to the existing literature, we conclude that the slipperiness of transparency discourses may ultimately have transformative implications for the relationship between science and society and that contemporary openness initiatives might be sowing the seeds for change to the status quo.
    MeSH term(s) Access to Information ; Animal Experimentation ; Disclosure ; Science ; Sociological Factors ; United Kingdom
    Language English
    Publishing date 2015-05-25
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1421272-9
    ISSN 1361-6609 ; 0963-6625
    ISSN (online) 1361-6609
    ISSN 0963-6625
    DOI 10.1177/0963662515586320
    Database MEDical Literature Analysis and Retrieval System OnLINE

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