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  1. Article ; Online: World No Tobacco Day 2021: Joining forces for tobacco control.

    D'Cruz, Anil

    Tobacco prevention & cessation

    2021  Volume 7, Page(s) 41

    Language English
    Publishing date 2021-05-29
    Publishing country Greece
    Document type Editorial
    ISSN 2459-3087
    ISSN (online) 2459-3087
    DOI 10.18332/tpc/138268
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: World Cancer Day 2021: A recognition of the COVID-19 heroes supporting and caring for cancer patients around the world.

    D'Cruz, Anil

    International journal of cancer

    2021  Volume 149, Issue 1, Page(s) 8–9

    MeSH term(s) COVID-19/epidemiology ; COVID-19/prevention & control ; COVID-19/virology ; Humans ; Medical Oncology/methods ; Medical Oncology/trends ; Neoplasms/diagnosis ; Neoplasms/therapy ; Pandemics ; SARS-CoV-2/isolation & purification ; SARS-CoV-2/physiology
    Language English
    Publishing date 2021-01-25
    Publishing country United States
    Document type Editorial
    ZDB-ID 218257-9
    ISSN 1097-0215 ; 0020-7136
    ISSN (online) 1097-0215
    ISSN 0020-7136
    DOI 10.1002/ijc.33480
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    Zs.A 478: Show issues Location:
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    Zs.MO 576: Show issues

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  3. Article ; Online: Proton Therapy and Incidence and Predisposing Factors of Osteoradionecrosis-On Pulling One's Punches.

    Nangia, Sapna / Joshua, Patrick / D'Cruz, Anil K

    JAMA otolaryngology-- head & neck surgery

    2023  Volume 149, Issue 6, Page(s) 558–559

    MeSH term(s) Humans ; Osteoradionecrosis/epidemiology ; Osteoradionecrosis/etiology ; Osteoradionecrosis/therapy ; Proton Therapy/adverse effects ; Incidence ; Causality
    Language English
    Publishing date 2023-04-20
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 2701825-8
    ISSN 2168-619X ; 2168-6181
    ISSN (online) 2168-619X
    ISSN 2168-6181
    DOI 10.1001/jamaoto.2023.0579
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  4. Article ; Online: World No Tobacco Day 2021

    Anil D'Cruz

    Tobacco Prevention and Cessation, Vol 7, Iss May, Pp 1-

    Joining forces for tobacco control

    2021  Volume 3

    Keywords cancer control ; wntd ; cancer ; fctc ; Public aspects of medicine ; RA1-1270
    Language English
    Publishing date 2021-05-01T00:00:00Z
    Publisher European Publishing
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article: Lenvatinib as a Promising Treatment Option for Unresectable Hürthle Cell Carcinoma: A Case Report.

    Shirode, Parth S / D'cruz, Anil / Chatterjee, Sataksi / Bhandarkar, Swayambhu

    Cureus

    2023  Volume 15, Issue 4, Page(s) e37460

    Abstract: Hürthle cell carcinoma (HCC) of the thyroid gland generally has a more aggressive clinical course than other differentiated thyroid cancers (DTCs), and it is associated with a higher rate of distant metastases. In this case report, we highlight the ... ...

    Abstract Hürthle cell carcinoma (HCC) of the thyroid gland generally has a more aggressive clinical course than other differentiated thyroid cancers (DTCs), and it is associated with a higher rate of distant metastases. In this case report, we highlight the importance of tyrosine kinase inhibitors as a management strategy for unresectable DTCs. Surgical management is challenging if the cancer is locally advanced and invades major neck structures with an increased risk of recurrence. Tyrosine kinase inhibitors (TKIs) are used in the case of advanced disease, especially in unresectable, radio-iodine refractory and with metastatic status. Lenvatinib, a TKI, used as the first line of treatment, plays a key role in improving prognosis and survival rates among patients. A 37-year-old gentleman presented with a locally advanced and widely metastasized case of large Hürthle cell carcinoma encasing the left carotid sheath and the left recurrent laryngeal nerve. Fine needle aspiration cytology (FNAC) was suggestive of HCC and a positron emission tomography-computed tomography (PET-CT) scan revealed metastases to the lungs and spine. In this case, lenvatinib was used to prevent the proliferation of malignant cells and the neovascularization of the tumor. This clinically translated into a good response in a high disease burden scenario. The patient showed positive results with lenvatinib therapy with a progression-free duration of 30 months and a reduction in the size of cancer. This case report describes the use of lenvatinib for the treatment of a large unresectable locally advanced and widely metastasized case of Hürthle cell carcinoma in a young gentleman with a response profile.
    Language English
    Publishing date 2023-04-11
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.37460
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  6. Article: Editorial: Site specific imaging guidelines in head & neck, and skull base cancers.

    Vaish, Richa / Mahajan, Abhishek / Ghosh Laskar, Sarbani / Prabhash, Kumar / Noronha, Vanita / D'Cruz, Anil K

    Frontiers in oncology

    2024  Volume 14, Page(s) 1357215

    Language English
    Publishing date 2024-01-18
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2649216-7
    ISSN 2234-943X
    ISSN 2234-943X
    DOI 10.3389/fonc.2024.1357215
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  7. Article ; Online: Risk-based oral cancer screening - lessons to be learnt.

    D'Cruz, Anil K / Vaish, Richa

    Nature reviews. Clinical oncology

    2021  Volume 18, Issue 8, Page(s) 471–472

    MeSH term(s) Early Detection of Cancer ; Humans ; Mouth Neoplasms/diagnosis ; Mouth Neoplasms/epidemiology
    Language English
    Publishing date 2021-04-21
    Publishing country England
    Document type Journal Article ; Comment
    ZDB-ID 2491410-1
    ISSN 1759-4782 ; 1759-4774
    ISSN (online) 1759-4782
    ISSN 1759-4774
    DOI 10.1038/s41571-021-00511-2
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    Zs.A 6029: Show issues Location:
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  8. Article ; Online: Giant cell tumor of hyoid bone: Diagnostic dilemma with a novel management.

    Bihani, Ameya / Thiagarajan, Shivakumar / Chaukar, Devendra / D'Cruz, Anil K

    Journal of cancer research and therapeutics

    2022  Volume 18, Issue 1, Page(s) 282–285

    Abstract: Giant cell tumor of bone (GCTB) is locally aggressive tumor occurring in the epiphysis of long bones. GCTBs are uncommon tumors in the head-and-neck region and rarely involve hyoid bone. We report a case of GCTB of hyoid bone. The patient presented with ... ...

    Abstract Giant cell tumor of bone (GCTB) is locally aggressive tumor occurring in the epiphysis of long bones. GCTBs are uncommon tumors in the head-and-neck region and rarely involve hyoid bone. We report a case of GCTB of hyoid bone. The patient presented with swelling in left submandibular region. The tumor was surgically excised after initial denosumab therapy. Despite adequate resection and rehabilitation, he was tube dependent. Subsequently it was found that the patient had a coexisting myotonic dystrophy, unknown to exist with GCTB of hyoid. Eventually, the patient succumbed to respiratory failure secondary to myotonic dystrophy. GCTB hyoid is a rare presentation posing a diagnostic dilemma. Ours is the first case to report the use of denosumab for GCT in head-and-neck region. Myotonic dystrophy Type I and GCTB are both known to result from abnormality of closely situated foci on chromosome 19.
    MeSH term(s) Bone Density Conservation Agents ; Bone Neoplasms/pathology ; Denosumab ; Giant Cell Tumor of Bone/diagnosis ; Giant Cell Tumor of Bone/surgery ; Humans ; Hyoid Bone/metabolism ; Hyoid Bone/pathology ; Male
    Chemical Substances Bone Density Conservation Agents ; Denosumab (4EQZ6YO2HI)
    Language English
    Publishing date 2022-04-05
    Publishing country India
    Document type Case Reports
    ZDB-ID 2187633-2
    ISSN 1998-4138 ; 0973-1482
    ISSN (online) 1998-4138
    ISSN 0973-1482
    DOI 10.4103/jcrt.JCRT_205_19
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Current evidences in poorly differentiated thyroid carcinoma: a systematic review and subsection meta-analysis for clinical decision making.

    Chatterjee, Sataksi / Mair, Manish / Shaha, Ashok R / Paleri, Vinidh / Sawhney, Shikhar / Mishra, Aananya / Bhandarkar, Swayambhu / D'Cruz, Anil Keith

    Endocrine

    2024  

    Abstract: Background: Poorly differentiated thyroid carcinoma (PDTC) is a distinct entity with intermediate prognosis between indolent follicular thyroid cancers and anaplastic carcinoma. The management guidelines are not standardized for these cancers due its ... ...

    Abstract Background: Poorly differentiated thyroid carcinoma (PDTC) is a distinct entity with intermediate prognosis between indolent follicular thyroid cancers and anaplastic carcinoma. The management guidelines are not standardized for these cancers due its low prevalence and limited available literature. Therefore, we did this systematic review with emphasis on current evidence on diagnosis, imaging, molecular markers, and management of these carcinomas.
    Materials and methods: We searched four databases, PubMed, Medline, EMBASE, and Emcare to identify studies published till October 2023. All studies reporting diagnostic tests, imaging, molecular marker expression and management of PDTC were included in the review. The meta-analysis was conducted on expression of molecular markers in these cancers following recommendations of the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). Random-effects meta-analysis was used to calculate pooled estimated prevalence with 95% confidence intervals. Based on the inclusion criteria, 62 articles were selected to be incorporated for the review. Differences in pathological diagnostic criteria of PDTC was noted in literature which was addressed in WHO 2022 diagnostic terminologies with expansion of the definition. Surgical management is uniformly recommended for early stage PDTC. However, literature is divided and anecdotal for recommendations on radioactive iodine (RAI), extent of neck dissection and adjuvant treatment in PDTC. Evidence for Next Generation Sequencing (NGS), novel theragnostic approaches, immunotherapy targets are evolving. Based on the subset analysis for expression of molecular markers, we found the most common markers expressed were TERT (41%), BRAF (28%) and P 53 (25%).
    Conclusion: Poorly differentiated thyroid carcinomas have a high case fatality rate (up to 31%). Eighty-five % of the patients who succumb to the disease have distant metastasis. Even though under-represented in literature, evidence-based management of these aggressive tumors can help personalize the treatment for optimal outcomes.
    Language English
    Publishing date 2024-03-19
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 1194484-5
    ISSN 1559-0100 ; 1355-008X ; 0969-711X
    ISSN (online) 1559-0100
    ISSN 1355-008X ; 0969-711X
    DOI 10.1007/s12020-024-03771-x
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    Zs.A 3884: Show issues Location:
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  10. Article ; Online: Comment on "Nationwide randomised trial evaluating elective neck dissection for early-stage oral cancer (SEND study) with meta-analysis and concurrent real-world cohort."

    Dhar, Harsh / Vaish, Richa / D'Cruz, Anil K

    British journal of cancer

    2020  Volume 123, Issue 7, Page(s) 1198–1199

    MeSH term(s) Cohort Studies ; Elective Surgical Procedures ; Humans ; Mouth Neoplasms/epidemiology ; Mouth Neoplasms/surgery ; Neck Dissection
    Language English
    Publishing date 2020-07-16
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 80075-2
    ISSN 1532-1827 ; 0007-0920
    ISSN (online) 1532-1827
    ISSN 0007-0920
    DOI 10.1038/s41416-020-0981-9
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