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  1. Article: Successful treatment of Brunsting-Perry pemphigoid with dupilumab.

    Blum, Franklin R / Sigmon, Justin R

    JAAD case reports

    2021  Volume 10, Page(s) 107–109

    Language English
    Publishing date 2021-02-23
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2834220-3
    ISSN 2352-5126
    ISSN 2352-5126
    DOI 10.1016/j.jdcr.2021.02.010
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  2. Article ; Online: Clustered painful pink papules with chest tightness.

    Sigmon, Justin R / Nathoo, Rajiv / Mullins, Stephen C / Sheehan, Daniel J

    International journal of dermatology

    2014  Volume 53, Issue 7, Page(s) 803–805

    MeSH term(s) Adult ; Chest Pain/etiology ; Hair Diseases/complications ; Hair Diseases/pathology ; Humans ; Leiomyomatosis/complications ; Leiomyomatosis/pathology ; Male ; Skin Neoplasms/complications ; Skin Neoplasms/pathology
    Language English
    Publishing date 2014-07
    Publishing country England
    Document type Case Reports ; Journal Article
    ZDB-ID 412254-9
    ISSN 1365-4632 ; 0011-9059 ; 1461-1244
    ISSN (online) 1365-4632
    ISSN 0011-9059 ; 1461-1244
    DOI 10.1111/ijd.12259
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  3. Article: Gianotti-Crosti syndrome associated with hepatitis A and influenza vaccination.

    Sigmon, Justin R / Venkatesh, Sheila / Lesher, Jack L

    Journal of drugs in dermatology : JDD

    2012  Volume 11, Issue 2, Page(s) 260–261

    MeSH term(s) Acrodermatitis/chemically induced ; Acrodermatitis/diagnosis ; Child, Preschool ; Hepatitis A Vaccines/adverse effects ; Humans ; Influenza Vaccines/adverse effects ; Male ; Vaccination/adverse effects
    Chemical Substances Hepatitis A Vaccines ; Influenza Vaccines
    Language English
    Publishing date 2012-02
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2145090-0
    ISSN 1545-9616
    ISSN 1545-9616
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  4. Article ; Online: Flesh-colored papule on the areola.

    Shlapak, Darya P / Sigmon, Justin R / Sheehan, Daniel J / Davis, Loretta S

    International journal of dermatology

    2013  Volume 52, Issue 11, Page(s) 1297–1299

    MeSH term(s) Adenoma/pathology ; Adolescent ; Apocrine Glands/pathology ; Breast ; Female ; Humans ; Skin Neoplasms/pathology
    Language English
    Publishing date 2013-11
    Publishing country England
    Document type Case Reports ; Journal Article
    ZDB-ID 412254-9
    ISSN 1365-4632 ; 0011-9059 ; 1461-1244
    ISSN (online) 1365-4632
    ISSN 0011-9059 ; 1461-1244
    DOI 10.1111/ijd.12080
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  5. Article ; Online: Adjunctive radiotherapy in the treatment of cutaneous squamous cell carcinoma with perineural invasion.

    Waxweiler, Weston / Sigmon, Justin R / Sheehan, Daniel J

    Journal of surgical oncology

    2011  Volume 104, Issue 1, Page(s) 104–105

    Abstract: Perineural invasion is a feature associated with significantly poorer outcomes when present in cutaneous squamous cell carcinoma (CSCC). The incidence of this subset of CSCC continues to rise in the US, as does the confusion surrounding exactly how it ... ...

    Abstract Perineural invasion is a feature associated with significantly poorer outcomes when present in cutaneous squamous cell carcinoma (CSCC). The incidence of this subset of CSCC continues to rise in the US, as does the confusion surrounding exactly how it should be managed. While management typically involves excision, considerable debate exists as to the appropriate use of adjuvant radiotherapy (ART) in addition to excision. This article reviews the current relevant evidence for the use of ART.
    MeSH term(s) Carcinoma, Squamous Cell/pathology ; Carcinoma, Squamous Cell/radiotherapy ; Humans ; Neoplasm Invasiveness ; Peripheral Nervous System Neoplasms/pathology ; Peripheral Nervous System Neoplasms/radiotherapy ; Radiotherapy, Adjuvant ; Skin Neoplasms/pathology ; Skin Neoplasms/radiotherapy
    Language English
    Publishing date 2011-07-01
    Publishing country United States
    Document type Letter ; Review
    ZDB-ID 82063-5
    ISSN 1096-9098 ; 0022-4790
    ISSN (online) 1096-9098
    ISSN 0022-4790
    DOI 10.1002/jso.21810
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    Zs.A 706: Show issues Location:
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  6. Article ; Online: Calcitriol ointment: a review of a topical vitamin D analog for psoriasis.

    Sigmon, Justin R / Yentzer, Brad A / Feldman, Steven R

    The Journal of dermatological treatment

    2009  Volume 20, Issue 4, Page(s) 208–212

    Abstract: Topical vitamin D analogs are a safe and effective treatment for psoriasis vulgaris. This is a brief review of calcitriol 3 microg/g ointment in the treatment of psoriasis. Calcitriol has been safely used outside the USA in Europe under the trade name ... ...

    Abstract Topical vitamin D analogs are a safe and effective treatment for psoriasis vulgaris. This is a brief review of calcitriol 3 microg/g ointment in the treatment of psoriasis. Calcitriol has been safely used outside the USA in Europe under the trade name Silkis Ointment for almost a decade in the treatment of psoriasis, and it is currently FDA-approved as Vectical Ointment. Calcitriol 3 microg/g ointment is a synthetic topical vitamin D analog considered to be as effective as other vitamin D analogs but with a better tolerability in sensitive areas.
    MeSH term(s) Administration, Cutaneous ; Calcitriol/administration & dosage ; Humans ; Ointments ; Psoriasis/drug therapy ; Vitamin D/analogs & derivatives
    Chemical Substances Ointments ; Vitamin D (1406-16-2) ; Calcitriol (FXC9231JVH)
    Language English
    Publishing date 2009
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 1036299-x
    ISSN 1471-1753 ; 0954-6634
    ISSN (online) 1471-1753
    ISSN 0954-6634
    DOI 10.1080/09546630902936810
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    Zs.A 2627: Show issues Location:
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  7. Article ; Online: Urticarial vasculitis: a unique presentation.

    Stigall, Landon E / Sigmon, Justin R / Leicht, Stuart S

    Southern medical journal

    2009  Volume 102, Issue 5, Page(s) 531–533

    Abstract: Urticarial vasculitis is a relatively rare diagnosis in a patient presenting with urticaria. The process is classically described as a generalized eruption, painful more so than pruritic, lasting longer than 24 hours. Two forms of urticarial vasculitis ... ...

    Abstract Urticarial vasculitis is a relatively rare diagnosis in a patient presenting with urticaria. The process is classically described as a generalized eruption, painful more so than pruritic, lasting longer than 24 hours. Two forms of urticarial vasculitis have been described: ahypocomplementemic form more commonly associated with systemic disease, and a normocomplementemic form that is generally limited to the skin. We report on a uniquely distributed vasculitic eruption restricted mainly to the anterior belt line area in a patient presenting with urticaria and intense pruritus. Urticarial vasculitis as a unique entity is reviewed along with its clinical and histopathologic presentation and the pharmacologic agents used for treatment.
    MeSH term(s) Adult ; Androstadienes/therapeutic use ; Anti-Allergic Agents/therapeutic use ; Anti-Inflammatory Agents/therapeutic use ; Colchicine/therapeutic use ; Drug Therapy, Combination ; Fluticasone ; Humans ; Male ; Neurodermatitis/drug therapy ; Prednisone/therapeutic use ; Pruritus/drug therapy ; Pruritus/etiology ; Urticaria/drug therapy ; Urticaria/etiology ; Vasculitis, Leukocytoclastic, Cutaneous/diagnosis ; Vasculitis, Leukocytoclastic, Cutaneous/drug therapy
    Chemical Substances Androstadienes ; Anti-Allergic Agents ; Anti-Inflammatory Agents ; Fluticasone (CUT2W21N7U) ; Colchicine (SML2Y3J35T) ; Prednisone (VB0R961HZT)
    Language English
    Publishing date 2009-05
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 185329-6
    ISSN 1541-8243 ; 0038-4348
    ISSN (online) 1541-8243
    ISSN 0038-4348
    DOI 10.1097/SMJ.0b013e3181a0ae4c
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  8. Article ; Online: Poorly differentiated carcinoma arising in the setting of erythema ab igne.

    Sigmon, Justin R / Cantrell, Jacob / Teague, Daniel / Sangueza, Omar / Sheehan, Daniel J

    The American Journal of dermatopathology

    2013  Volume 35, Issue 6, Page(s) 676–678

    Abstract: Erythema ab igne (EAI) is a reticulated, erythematous, or hyperpigmented dermatosis that is caused by chronic exposure to infrared radiation. Chronic lesions of EAI have significant potential for malignant transformation. We report a case of poorly ... ...

    Abstract Erythema ab igne (EAI) is a reticulated, erythematous, or hyperpigmented dermatosis that is caused by chronic exposure to infrared radiation. Chronic lesions of EAI have significant potential for malignant transformation. We report a case of poorly differentiated carcinoma arising within a patch of long-standing EAI on the lower extremity of a 92-year-old female. This case highlights the importance of recognizing EAI early and counseling patients to avoid further exposure to the offending infrared source to reduce the risk of malignant transformation. EAI has been associated with several different types of cutaneous neoplasms including the Merkel cell carcinoma, squamous cell carcinoma, and cutaneous marginal zone lymphoma.
    MeSH term(s) Aged, 80 and over ; Biopsy ; Carcinoma/etiology ; Carcinoma/pathology ; Cell Differentiation ; Erythema/etiology ; Erythema/pathology ; Female ; Humans ; Hyperpigmentation/etiology ; Hyperpigmentation/pathology ; Infrared Rays/adverse effects ; Neoplasms, Radiation-Induced/etiology ; Neoplasms, Radiation-Induced/pathology ; Precancerous Conditions/etiology ; Precancerous Conditions/pathology ; Predictive Value of Tests ; Risk Factors ; Skin Neoplasms/etiology ; Skin Neoplasms/pathology
    Language English
    Publishing date 2013-08
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 448469-1
    ISSN 1533-0311 ; 0193-1091
    ISSN (online) 1533-0311
    ISSN 0193-1091
    DOI 10.1097/DAD.0b013e3182871648
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    Zs.A 1518: Show issues Location:
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  9. Article ; Online: X-linked agammaglobulinemia diagnosed late in life: case report and review of the literature.

    Sigmon, Justin R / Kasasbeh, Ehab / Krishnaswamy, Guha

    Clinical and molecular allergy : CMA

    2008  Volume 6, Page(s) 5

    Abstract: Background: Common variable immune deficiency (CVID), one of the most common primary immunodeficiency diseases presents in adults, whereas X-linked agammaglobulinemia (XLA), an inherited humoral immunodeficiency, is usually diagnosed early in life after ...

    Abstract Background: Common variable immune deficiency (CVID), one of the most common primary immunodeficiency diseases presents in adults, whereas X-linked agammaglobulinemia (XLA), an inherited humoral immunodeficiency, is usually diagnosed early in life after maternal Igs have waned. However, there have been several reports in the world literature in which individuals have either had a delay in onset of symptoms or have been misdiagnosed with CVID and then later found to have mutations in Bruton's tyrosine kinase (BTK) yielding a reclassification as adult-onset variants of XLA. The typical finding of absent B cells should suggest XLA rather than CVID and may be a sensitive test to detect this condition, leading to the more specific test (Btk mutational analysis). Further confirmation may be by mutational analyses.
    Methods: The records of 2 patients were reviewed and appropriate clinical data collected. BTK mutational analysis was carried out to investigate the suspicion of adult-presentation of XLA. A review of the world literature on delayed diagnosis of XLA and mild or "leaky" phenotype was performed.
    Results: 2 patients previously diagnosed with CVID associated with virtual absence of CD19+ B cells were reclassified as having a delayed diagnosis and adult-presentation of XLA. Patient 1, a 64 yr old male with recurrent sinobronchial infections had a low level of serum IgG of 360 mg/dl (normal 736-1900), IgA <27 mg/dl (normal 90-474), and IgM <25 mg/dl (normal 50-415). Patient 2, a 46 yr old male with recurrent sinopulmonary infections had low IgG of 260 mg/dl, low IgA <16 mg/dl, and normal IgM. Mutational analysis of BTK was carried out in both patients and confirmed the diagnosis of XLA CONCLUSION: These two cases represent an unusual adult-presentation of XLA, a humoral immunodeficiency usually diagnosed in childhood and the need to further investigate a suspicion of XLA in adult males with CVID particularly those associated with low to absent CD19+ B cells. A diagnosis of XLA can have significant implications including family counseling, detecting female carriers, and early intervention and treatment of affected male descendents.
    Language English
    Publishing date 2008-06-02
    Publishing country England
    Document type Journal Article
    ISSN 1476-7961
    ISSN (online) 1476-7961
    DOI 10.1186/1476-7961-6-5
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  10. Article ; Online: Bullosis diabeticorum associated with a prediabetic state.

    Lopez, Pablo R / Leicht, Stuart / Sigmon, Justin R / Stigall, Landon

    Southern medical journal

    2009  Volume 102, Issue 6, Page(s) 643–644

    Abstract: Bullosis diabeticorum, or diabetic bullae, is a non-inflammatory blistering condition that is virtually diagnostic of diabetes. Diabetic bullae most often present as painless, tense, superficial bullae that occur in an acral distribution and commonly ... ...

    Abstract Bullosis diabeticorum, or diabetic bullae, is a non-inflammatory blistering condition that is virtually diagnostic of diabetes. Diabetic bullae most often present as painless, tense, superficial bullae that occur in an acral distribution and commonly heal in 2-6 weeks without scarring, but complications such as secondary bacterial infection or hemorrhage may occur. The diagnosis of bullosis diabeticorum in a nondiabetic patient should prompt screening for diabetes. A case of recurrent bullae in a prediabetic patient is presented, with a review of the clinical features and significance of bullosis diabeticorum.
    MeSH term(s) Aged, 80 and over ; Blood Glucose/analysis ; Female ; Humans ; Prediabetic State/complications ; Prediabetic State/diagnosis ; Prediabetic State/pathology ; Skin/pathology ; Skin Diseases, Vesiculobullous/diagnosis ; Skin Diseases, Vesiculobullous/etiology ; Skin Diseases, Vesiculobullous/pathology
    Chemical Substances Blood Glucose
    Language English
    Publishing date 2009-06
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 185329-6
    ISSN 1541-8243 ; 0038-4348
    ISSN (online) 1541-8243
    ISSN 0038-4348
    DOI 10.1097/SMJ.0b013e3181a506d6
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