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  1. Article ; Online: Vincenzo Pavone: Friend, mentor and inspiring scientist.

    Nastri, Flavia / Maglio, Ornella / Lombardi, Angela

    Biopolymers

    2018  Volume 109, Issue 10, Page(s) e23234

    MeSH term(s) Chemistry/education ; Chemistry/history ; Faculty ; Friends ; History, 20th Century ; History, 21st Century ; Humans ; Mentors/history ; Models, Molecular
    Language English
    Publishing date 2018-11-05
    Publishing country United States
    Document type Biography ; Editorial ; Festschrift ; Historical Article ; Portrait
    ZDB-ID 1123-x
    ISSN 1097-0282 ; 0006-3525
    ISSN (online) 1097-0282
    ISSN 0006-3525
    DOI 10.1002/bip.23234
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 77: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  2. Article ; Online: Management of Takayasu arteritis diagnosed during pregnancy: A case report.

    Arezzo, Francesca / Venerito, Vincenzo / Iannone, Florenzo / Lombardi, Claudio

    Archives of rheumatology

    2020  Volume 36, Issue 1, Page(s) 138–139

    Language English
    Publishing date 2020-06-25
    Publishing country Turkey
    Document type Journal Article
    ZDB-ID 3012972-2
    ISSN 2618-6500 ; 2148-5046
    ISSN (online) 2618-6500
    ISSN 2148-5046
    DOI 10.46497/ArchRheumatol.2021.8023
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  3. Article ; Online: How should we differentiate hypoglycaemia in non-diabetic patients?

    Modestino, Michele R / Iacono, Olimpia / Ferrentino, Laura / Lombardi, Anna / De Fortuna, Umberto / Verdoliva, Rita / De Luca, Mariarosaria / Guardasole, Vincenzo

    Journal of basic and clinical physiology and pharmacology

    2024  

    Abstract: Hypoglycaemic syndromes are rare in apparently healthy individuals and their diagnosis can be a difficult challenge for clinicians as there are no shared guidelines that suggest how to approach patients with a suspect hypoglycaemic disorder. Since ... ...

    Abstract Hypoglycaemic syndromes are rare in apparently healthy individuals and their diagnosis can be a difficult challenge for clinicians as there are no shared guidelines that suggest how to approach patients with a suspect hypoglycaemic disorder. Since hypoglycaemia symptoms are common and nonspecific, it's necessary to document the Whipple Triad (signs and/or symptoms compatible with hypoglycaemia; relief of symptoms following glucose administration; low plasma glucose levels) before starting any procedure. Once the triad is documented, a meticulous anamnesis and laboratory tests (blood glucose, insulin, proinsulin, C-peptide, β-hydroxybutyrate and anti-insulin antibodies) should be performed. Results can guide the physician towards further specific tests, concerning the suspected disease. In this review, we consider all current causes of hypoglycaemia, including rare diseases such as nesidioblastosis and Hirata's syndrome, describe appropriate tests for diagnosis and suggest strategies to differentiate hypoglycaemia aetiology.
    Language English
    Publishing date 2024-04-16
    Publishing country Germany
    Document type Journal Article ; Review
    ZDB-ID 1071737-7
    ISSN 2191-0286 ; 0792-6855 ; 0334-1534
    ISSN (online) 2191-0286
    ISSN 0792-6855 ; 0334-1534
    DOI 10.1515/jbcpp-2024-0030
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3207: Show issues Location:
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  4. Article ; Online: First isolation of Mycobacterium saskatchewanense from medical devices.

    Bisognin, Francesco / Ferraro, Vincenzo / Sorella, Federica / Lombardi, Giulia / Lazzarotto, Tiziana / Dal Monte, Paola

    Scientific reports

    2023  Volume 13, Issue 1, Page(s) 21628

    Abstract: Mycobacterium saskatchewanense is a species of pigmented slow-growing Non-Tuberculous Mycobacteria (NTM), positive for Mycobacterium avium complex (MAC) by AccuProbe system. MAC organisms have frequently been isolated from different medical devices. This ...

    Abstract Mycobacterium saskatchewanense is a species of pigmented slow-growing Non-Tuberculous Mycobacteria (NTM), positive for Mycobacterium avium complex (MAC) by AccuProbe system. MAC organisms have frequently been isolated from different medical devices. This is the first study reporting isolation of M. saskatchewanense from medical devices and highlights the importance of correctly identifying the NTMs that often colonize sanitary water. GenoType Mycobacterium CM CE-IVD kit (CM) was used as the first step of NTM strain identification, and all positive cultures were found to be components of MAC. Then, GenoType NTM-DR CE-IVD kit (NTM-DR) was used to differentiate the different species. Sub-culture on solid media were used for: (i) phenotypical confirmation by colony morphology and Matrix-Assisted Laser Desorption/Ionization-Time of Flight (MALDI-TOF) mass spectrometry; (ii) molecular confirmation by Next Generation Sequencing. All positive cultures were identified as M. intracellulare by CM and NTM-DR assays, whereas colony morphology showed bright yellow scotochromogenic growth. MALDI-TOF analyses identified the strains as M. saskatchewanense with a high score, and identification was confirmed by NGS analysis based on the hsp-65 region. This paper suggests that it is important to actively monitor NTM contamination in medical devices that use sanitary water, to prevent the possibility of patients becoming infected.
    MeSH term(s) Humans ; Mycobacterium ; Nontuberculous Mycobacteria/genetics ; Mycobacterium avium Complex/genetics ; Mycobacterium Infections, Nontuberculous/microbiology ; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization/methods ; Water
    Chemical Substances Water (059QF0KO0R)
    Language English
    Publishing date 2023-12-07
    Publishing country England
    Document type Journal Article
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-023-48974-w
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  5. Article ; Online: Sarcomere level mechanics of the fast skeletal muscle of the medaka fish larva.

    Marcello, Matteo / Cetrangolo, Viviana / Morotti, Ilaria / Squarci, Caterina / Caremani, Marco / Reconditi, Massimo / Savarese, Marco / Bianco, Pasquale / Piazzesi, Gabriella / Lombardi, Vincenzo / Udd, Bjarne / Conte, Ivan / Nigro, Vincenzo / Linari, Marco

    American journal of physiology. Cell physiology

    2023  Volume 326, Issue 2, Page(s) C632–C644

    Abstract: The medaka fish ( ...

    Abstract The medaka fish (
    MeSH term(s) Animals ; Humans ; Sarcomeres/metabolism ; Oryzias/metabolism ; Larva/metabolism ; Muscle, Skeletal/metabolism ; Myosins/metabolism ; Muscular Diseases ; Muscle Contraction/physiology
    Chemical Substances Myosins (EC 3.6.4.1)
    Language English
    Publishing date 2023-12-25
    Publishing country United States
    Document type Journal Article
    ZDB-ID 392098-7
    ISSN 1522-1563 ; 0363-6143
    ISSN (online) 1522-1563
    ISSN 0363-6143
    DOI 10.1152/ajpcell.00530.2023
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    In stock of ZB MED Cologne/Königswinter

    Uc I Zs.89: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
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  6. Article ; Online: Force and kinetics of fast and slow muscle myosin determined with a synthetic sarcomere-like nanomachine.

    Buonfiglio, Valentina / Pertici, Irene / Marcello, Matteo / Morotti, Ilaria / Caremani, Marco / Reconditi, Massimo / Linari, Marco / Fanelli, Duccio / Lombardi, Vincenzo / Bianco, Pasquale

    Communications biology

    2024  Volume 7, Issue 1, Page(s) 361

    Abstract: Myosin II is the muscle molecular motor that works in two bipolar arrays in each thick filament of the striated (skeletal and cardiac) muscle, converting the chemical energy into steady force and shortening by cyclic ATP-driven interactions with the ... ...

    Abstract Myosin II is the muscle molecular motor that works in two bipolar arrays in each thick filament of the striated (skeletal and cardiac) muscle, converting the chemical energy into steady force and shortening by cyclic ATP-driven interactions with the nearby actin filaments. Different isoforms of the myosin motor in the skeletal muscles account for the different functional requirements of the slow muscles (primarily responsible for the posture) and fast muscles (responsible for voluntary movements). To clarify the molecular basis of the differences, here the isoform-dependent mechanokinetic parameters underpinning the force of slow and fast muscles are defined with a unidimensional synthetic nanomachine powered by pure myosin isoforms from either slow or fast rabbit skeletal muscle. Data fitting with a stochastic model provides a self-consistent estimate of all the mechanokinetic properties of the motor ensemble including the motor force, the fraction of actin-attached motors and the rate of transition through the attachment-detachment cycle. The achievements in this paper set the stage for any future study on the emergent mechanokinetic properties of an ensemble of myosin molecules either engineered or purified from mutant animal models or human biopsies.
    MeSH term(s) Animals ; Humans ; Rabbits ; Sarcomeres ; Muscle Contraction/physiology ; Myosins ; Muscle, Skeletal/physiology ; Protein Isoforms/chemistry
    Chemical Substances Myosins (EC 3.6.4.1) ; Protein Isoforms
    Language English
    Publishing date 2024-03-23
    Publishing country England
    Document type Journal Article
    ISSN 2399-3642
    ISSN (online) 2399-3642
    DOI 10.1038/s42003-024-06033-8
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  7. Book ; Conference proceedings: Acta (articles and abstracts) of the Fourth International Symposium "New Frontiers of Biochemistry, Biophysics on Diagnosis and Treatment of Stroke, Neurotrauma and Other Neurological Disorders"

    Lombardi, Vincenzo

    Firenze, April 19th, 20th, 21st, 1989 ; "... to arrest the catastrophe of stroke and paraplegia"

    1989  

    Event/congress International Symposium New Frontiers of Biochemistry, Biophysics on Diagnosis and Treatment of Stroke, Neurotrauma and Other Neurological Disorders (4, 1989, Florenz)
    Author's details ed. by V. Lombardi
    Keywords Nervous System Diseases / diagnosis / congresses ; Nervous System Diseases / therapy / congresses ; Nervous System Diseases / metabolism / congresses ; Diagnostic Imaging / congresses
    Language English
    Size 103 S. : graph. Darst.
    Publisher Arti Grafiche De Tullio
    Publishing place Bari
    Publishing country Italy
    Document type Book ; Conference proceedings
    HBZ-ID HT007824080
    Database Catalogue ZB MED Medicine, Health

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    1997 A 7797 order for loan Magazin

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  8. Article ; Online: Selective Oxidation of Halophenols Catalyzed by an Artificial Miniaturized Peroxidase.

    D'Alonzo, Daniele / De Fenza, Maria / Pavone, Vincenzo / Lombardi, Angela / Nastri, Flavia

    International journal of molecular sciences

    2023  Volume 24, Issue 9

    Abstract: The development of artificial enzymes for application in sustainable technologies, such as the transformation of environmental pollutants or biomass, is one of the most challenging goals in metalloenzyme design. In this work, we describe the oxidation of ...

    Abstract The development of artificial enzymes for application in sustainable technologies, such as the transformation of environmental pollutants or biomass, is one of the most challenging goals in metalloenzyme design. In this work, we describe the oxidation of mono-, di-, tri- and penta-halogenated phenols catalyzed by the artificial metalloenzyme Fe-MC6*a. It promoted the dehalogenation of 4-fluorophenol into the corresponding 1,4-benzoquinone, while under the same experimental conditions, 4-chloro, 4-bromo and 4-iodophenol were selectively converted into higher molecular weight compounds. Analysis of the 4-chlorophenol oxidation products clarified that oligomers based on C-O bonds were exclusively formed in this case. All results show that Fe-MC6*a holds intriguing enzymatic properties, as it catalyzes halophenol oxidation with substrate-dependent chemoselectivity.
    MeSH term(s) Peroxidase ; Peroxidases/metabolism ; Oxidation-Reduction ; Catalysis
    Chemical Substances Peroxidase (EC 1.11.1.7) ; Peroxidases (EC 1.11.1.-)
    Language English
    Publishing date 2023-04-29
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms24098058
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  9. Article ; Online: First isolation of Mycobacterium saskatchewanense from medical devices

    Francesco Bisognin / Vincenzo Ferraro / Federica Sorella / Giulia Lombardi / Tiziana Lazzarotto / Paola Dal Monte

    Scientific Reports, Vol 13, Iss 1, Pp 1-

    2023  Volume 4

    Abstract: Abstract Mycobacterium saskatchewanense is a species of pigmented slow-growing Non-Tuberculous Mycobacteria (NTM), positive for Mycobacterium avium complex (MAC) by AccuProbe system. MAC organisms have frequently been isolated from different medical ... ...

    Abstract Abstract Mycobacterium saskatchewanense is a species of pigmented slow-growing Non-Tuberculous Mycobacteria (NTM), positive for Mycobacterium avium complex (MAC) by AccuProbe system. MAC organisms have frequently been isolated from different medical devices. This is the first study reporting isolation of M. saskatchewanense from medical devices and highlights the importance of correctly identifying the NTMs that often colonize sanitary water. GenoType Mycobacterium CM CE-IVD kit (CM) was used as the first step of NTM strain identification, and all positive cultures were found to be components of MAC. Then, GenoType NTM-DR CE-IVD kit (NTM-DR) was used to differentiate the different species. Sub-culture on solid media were used for: (i) phenotypical confirmation by colony morphology and Matrix-Assisted Laser Desorption/Ionization-Time of Flight (MALDI-TOF) mass spectrometry; (ii) molecular confirmation by Next Generation Sequencing. All positive cultures were identified as M. intracellulare by CM and NTM-DR assays, whereas colony morphology showed bright yellow scotochromogenic growth. MALDI-TOF analyses identified the strains as M. saskatchewanense with a high score, and identification was confirmed by NGS analysis based on the hsp-65 region. This paper suggests that it is important to actively monitor NTM contamination in medical devices that use sanitary water, to prevent the possibility of patients becoming infected.
    Keywords Medicine ; R ; Science ; Q
    Language English
    Publishing date 2023-12-01T00:00:00Z
    Publisher Nature Portfolio
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  10. Book ; Conference proceedings: New frontiers of biochemistry and treatment of stroke and brain spinal cord injury

    Lombardi, Vincenzo

    acta (articles and abstracts) of the Third Internat. Sympos. [New Frontiers of Biochemistry and Treatment of Stroke and Brain Spinal Cord Injury] ; keyrole of membrane transport ATPases and neurotransmitters intermodulation in NS ; ATPases in vitro and in vivo by NMR and EPR ; similarity of dismetabolic cytotoxic and vasogenic phenomena in stroke and neurotrauma ; management, pharmacolog. and surg. treatment ; a cooperative study ; Firenze, Sept. 29 - 30, 1987

    1987  

    Event/congress International Symposium New Frontiers of Biochemistry and Treatment of Stroke and Brain Spinal Cord Injury (1987, Florenz)
    Author's details ed. by V. Lombardi
    Keywords Cerebrovascular Disorders / congresses ; Brain Injuries / congresses ; Spinal Cord Injuries / congresses
    Size 63 S. : Ill., graph. Darst.
    Publishing place s.l.
    Publishing country Italy
    Document type Book ; Conference proceedings
    HBZ-ID HT003110241
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    1988 A 2149 order for loan Magazin

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