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Article ; Online: U.S. Food and Drug Administration Updates in Nutrition Labeling: What Clinicians Need to Know.

Warraich, Haider J / Carroll, Laura / McKinnon, Robin A / Kavanaugh, Claudine / Califf, Robert M

2024 Volume 177, Issue 4, Page(s) 532–534

MeSH term(s)	United States ; Humans ; Food Labeling ; United States Food and Drug Administration ; Drug Labeling
Language	English
Publishing date	2024-03-12
Publishing country	United States
Document type	Editorial
ZDB-ID	336-0
ISSN	1539-3704 ; 0003-4819
ISSN (online)	1539-3704
ISSN	0003-4819
DOI	10.7326/M23-3266
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Article: YIMBY-Yes, In My BackYard!-The successful transition to a local online ecology field course.

McKinnon, Laura

Ecology and evolution

2020 Volume 10, Issue 22, Page(s) 12542–12548

Abstract: Field biology courses provide the ultimate experiential education as students discover the links between theory and practice in ecology and evolution directly in nature. During the spring and summer of 2020, the COVID-19 pandemic led to the cancelation ... ...

Abstract	Field biology courses provide the ultimate experiential education as students discover the links between theory and practice in ecology and evolution directly in nature. During the spring and summer of 2020, the COVID-19 pandemic led to the cancelation of face-to-face classes in almost every university in Canada. Whereas traditional university courses were mostly transferred online, the online transition for field biology courses was not so common. Here, I provide an account of a successful transition from traditional field biology course to an online "backyard biology" field course with a small class size of 10 students. While the online field course may not provide the same level of interpersonal benefits of the traditional field course experience, the model outlined here demonstrates that an online field course that incorporates direct experience with the natural environment is possible and should no longer be considered an oxymoron.
Language	English
Publishing date	2020-10-07
Publishing country	England
Document type	Journal Article
ZDB-ID	2635675-2
ISSN	2045-7758
ISSN	2045-7758
DOI	10.1002/ece3.6881
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Article ; Online: A structural comparison of salt forms of dopamine with the structures of other phenylethylamines.

Kennedy, Alan R / Cruickshank, Laura / Maher, Pamela / McKinnon, Zoe

Acta crystallographica. Section C, Structural chemistry

2023 Volume 79, Issue Pt 10, Page(s) 386–394

Abstract: The structures of four salt forms of dopamine are reported. These are dopamine [2-(3,4-dihydroxyphenyl)ethan-1-aminium] benzoate, ... ...

Abstract	The structures of four salt forms of dopamine are reported. These are dopamine [2-(3,4-dihydroxyphenyl)ethan-1-aminium] benzoate, C
Language	English
Publishing date	2023-09-11
Publishing country	England
Document type	Journal Article
ZDB-ID	2025703-X
ISSN	2053-2296 ; 1600-5759 ; 0108-2701
ISSN (online)	2053-2296 ; 1600-5759
ISSN	0108-2701
DOI	10.1107/S2053229623007696
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Article ; Online: YIMBY—Yes, In My BackYard!—The successful transition to a local online ecology field course

Laura McKinnon

Ecology and Evolution, Vol 10, Iss 22, Pp 12542-

2020 Volume 12548

Abstract: Abstract Field biology courses provide the ultimate experiential education as students discover the links between theory and practice in ecology and evolution directly in nature. During the spring and summer of 2020, the COVID‐19 pandemic led to the ... ...

Abstract	Abstract Field biology courses provide the ultimate experiential education as students discover the links between theory and practice in ecology and evolution directly in nature. During the spring and summer of 2020, the COVID‐19 pandemic led to the cancelation of face‐to‐face classes in almost every university in Canada. Whereas traditional university courses were mostly transferred online, the online transition for field biology courses was not so common. Here, I provide an account of a successful transition from traditional field biology course to an online “backyard biology” field course with a small class size of 10 students. While the online field course may not provide the same level of interpersonal benefits of the traditional field course experience, the model outlined here demonstrates that an online field course that incorporates direct experience with the natural environment is possible and should no longer be considered an oxymoron.
Keywords	experiential education ; field course ; online ; urban ecology ; Ecology ; QH540-549.5
Subject code	028
Language	English
Publishing date	2020-11-01T00:00:00Z
Publisher	Wiley
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: YIMBY—Yes, In My BackYard!—The successful transition to a local online ecology field course

McKinnon, Laura

Ecology and Evolution

Abstract: Abstract Field biology courses provide the ultimate experiential education as students discover the links between theory and practice in ecology and evolution directly in nature During the spring and summer of 2020, the COVID-19 pandemic led to the ... ...

Abstract	Abstract Field biology courses provide the ultimate experiential education as students discover the links between theory and practice in ecology and evolution directly in nature During the spring and summer of 2020, the COVID-19 pandemic led to the cancelation of face-to-face classes in almost every university in Canada Whereas traditional university courses were mostly transferred online, the online transition for field biology courses was not so common Here, I provide an account of a successful transition from traditional field biology course to an online ?backyard biology? field course with a small class size of 10 students While the online field course may not provide the same level of interpersonal benefits of the traditional field course experience, the model outlined here demonstrates that an online field course that incorporates direct experience with the natural environment is possible and should no longer be considered an oxymoron
Keywords	covid19
Publisher	WHO
Document type	Article
Note	WHO #Covidence: #833872
Database	COVID19

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Article ; Online: Queering food security research: A critical analysis of 2SLGBTQ+ People's experiences of food insecurity in Toronto during the COVID-19 pandemic.

Gibb, James K / Williams, Sarah / Mikelsteins, Kaspars / Charles, Jada / McKinnon, Leela / Beach, Laura / McKerracher, Luseadra / Fields, Jessica

Social science & medicine (1982)

2024 Volume 345, Page(s) 116709

Abstract: Introduction: Household food insecurity (HFI), stress, isolation, and discrimination are major determinants of health that disproportionately affect 2SLGBTQ + people. The COVID-19 pandemic potentially exacerbated these inequities. This study ... ...

Abstract	Introduction: Household food insecurity (HFI), stress, isolation, and discrimination are major determinants of health that disproportionately affect 2SLGBTQ + people. The COVID-19 pandemic potentially exacerbated these inequities. This study investigates HFI rates among 2SLGBTQ + adults living in diverse household conditions during the pandemic and explores the idea that heteronormative conceptions of the "household" may affect measurement of HFI. Methods: Cross-sectional survey responses were collected from 437 self-identified 2SLGBTQ + people from Toronto, Canada between March and July 2021. The survey measured HFI, sexual/gender identities, socio-demographic factors, household composition, and psycho-social stress/distress. Multinomial logistic regression was used to assess variation in odds of marginal, moderate, and severe HFI in relation to sexual/gender identities, household composition, psycho-social distress, and socio-demographic covariates. Results: Forty-two percent of respondents reported some level of HFI, with severe HFI higher among respondents who were bisexual, transgender/gender diverse, and/or assigned-female-at-birth. Living alone was associated with decreased odds of reporting marginal HFI but increased odds of moderate or severe HFI compared to living with a partner, family, or roommates; living with children was associated with decreased odds of both marginal and severe HFI. One indicator of psycho-social distress (perceived discrimination) was associated with higher odds of all levels of HFI, while the other (isolation) was associated with decreased odds of marginal HFI. Conclusion: These findings highlight the high prevalence of HFI linked with discrimination among 2SLGBTQ + individuals during the pandemic. The complicated results regarding household composition and social isolation may suggest a need to revise definitions of the household when measuring, monitoring, and seeking to mitigate HFI in 2SLGBTQ + communities.
MeSH term(s)	Adult ; Child ; Humans ; Female ; Pandemics ; Cross-Sectional Studies ; Food Supply ; COVID-19/epidemiology ; Sexual and Gender Minorities ; Food Security ; Food Insecurity ; Gender Identity
Language	English
Publishing date	2024-02-23
Publishing country	England
Document type	Journal Article
ZDB-ID	4766-1
ISSN	1873-5347 ; 0037-7856 ; 0277-9536
ISSN (online)	1873-5347
ISSN	0037-7856 ; 0277-9536
DOI	10.1016/j.socscimed.2024.116709
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Zs.A 625: Show issues

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Article ; Online: Rushing in the spring and relaxing in the fall

Leah Wright / Erica Nol / Richard B. Lanctot / Laura McKinnon

Journal of Field Ornithology, Vol 93, Iss 2, p

seasonal and sex-specific migration profiles of Dunlin

2022 Volume 10

Abstract: Developing effective species conservation strategies relies on our ability to understand the spatiotemporal distribution of birds across their annual cycle. Assessing the connectivity between breeding and non-breeding areas remains challenging in ... ...

Abstract	Developing effective species conservation strategies relies on our ability to understand the spatiotemporal distribution of birds across their annual cycle. Assessing the connectivity between breeding and non-breeding areas remains challenging in migratory species that may exhibit intraspecific variation in migration strategies. Here we use light-level geolocation to test for sex-specific differences in the migration strategies (i.e. migration routes, stopovers, and wintering sites) of a population of Dunlin (Calidris alpina hudsonia) that breeds in Churchill, Manitoba, Canada. Churchill Dunlin exhibited relatively weak connectivity, as birds spread out evenly across the Atlantic Coast south of New Jersey, U.S.A, and the Gulf Coast from Mexico to Florida, U.S.A., the entire known non-breeding range of the species. We did identify important concentrated stopovers in James Bay, ON, Canada and along the coast of Delaware, U.S.A. Overall migration and stopover durations were significantly shorter during spring (northward) compared to fall (southward) migration. During spring migration, males followed a more direct migration route than females. In fall, male Dunlin departed breeding grounds earlier and spent more time on migration than females, likely driven by a trend of longer stopover durations. These sex-specific differences suggest that in spring, males deploy an energy minimization strategy to reach breeding grounds quickly and select the highest quality mating territories, whereas in fall, males take a much more relaxed migration. This research sheds light on the least understood period of the avian life cycle and informs our ability to target conservation initiatives to locations most important for this species.
Keywords	annual cycle ; calidris alpina ; dunlin ; geolocators ; migration ; sex-specific ; stopovers ; Zoology ; QL1-991 ; Animal culture ; SF1-1100
Subject code	590
Language	English
Publishing date	2022-06-01T00:00:00Z
Publisher	Resilience Alliance
Document type	Article ; Online
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Article ; Online: Serous Tubal Intraepithelial Carcinoma in a Risk-reducing Salpingo-oophorectomy Specimen From a RAD51D Mutation Carrier: A Case Report.

Gregory-Davis, Kalin J / Walker, Allison / Colello, Laura S / McKinnon, Wendy / Everett, Elise / Chang, Martin C

International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists

2022 Volume 42, Issue 1, Page(s) 89–92

Abstract: The RAD51D gene codes a protein-paralog of the RAD51 DNA recombinase, which catalyzes DNA strand exchange during homologous recombination. Similar to BRCA1 / BRCA2 , mutations in RAD51D both predispose to ovarian carcinoma and impart sensitivity to poly ( ...

Abstract	The RAD51D gene codes a protein-paralog of the RAD51 DNA recombinase, which catalyzes DNA strand exchange during homologous recombination. Similar to BRCA1 / BRCA2 , mutations in RAD51D both predispose to ovarian carcinoma and impart sensitivity to poly (ADP-ribose) polymerase inhibitors in preclinical studies. Based on cancer risk prediction models, RAD51D mutations pose a moderate-to-high risk for ovarian cancer warranting consideration for risk-reducing surgery. We report a case of serous tubal intraepithelial carcinoma in a patient undergoing risk-reducing total hysterectomy with bilateral salpingo-oophorectomy for a RAD51D pathogenic variant. The histopathologic and p53-immunophenotypic features of this lesion are similar to those reported previously in BRCA1 / BRCA2 mutation carriers and those of serous tubal intraepithelial carcinoma associated with sporadic high-grade serous carcinomas. These features include marked increase in nuclear-to-cytoplasmic ratio, loss of cell polarity, absence of ciliation, prominent nucleoli, mitotic activity, epithelial stratification, surface exfoliative changes, and complete loss of p53 staining. Although familial ovarian cancers with mutations in RAD51D -or other genes in the Fanconi anemia pathway-are much less common those with BRCA1 / BRCA2 mutations, our findings support a common phenotype for early serous cancers in this pathway.
Language	English
Publishing date	2022-02-11
Publishing country	United States
Document type	Journal Article
ZDB-ID	604859-6
ISSN	1538-7151 ; 0277-1691
ISSN (online)	1538-7151
ISSN	0277-1691
DOI	10.1097/PGP.0000000000000857
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Zs.A 1814: Show issues

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Article ; Online: Head supported mass, moment of inertia, neck loads and stability: A simulation study.

Barrett, Jeff M / Healey, Laura A / McKinnon, Colin D / Laing, Andrew C / Dickerson, Clark R / Fischer, Steven L / Callaghan, Jack P

Journal of biomechanics

2022 Volume 146, Page(s) 111416

Abstract: Occupations or activities where donning head-supported mass (HSM) is commonplace put operators at an elevated risk of chronic neck pain. Yet, there is no consensus about what features of HSM influence the relative contributions to neck loads. Therefore, ... ...

Abstract	Occupations or activities where donning head-supported mass (HSM) is commonplace put operators at an elevated risk of chronic neck pain. Yet, there is no consensus about what features of HSM influence the relative contributions to neck loads. Therefore, we tested four hypotheses that could increase neck loads: (i) HSM increases gravitational moments; (ii) more muscle activation is required to stabilize the head with HSM; (iii) the position of the HSM centre of mass (COM) induces gravitational moments; and (iv) the added moment of inertia (MOI) from HSM increases neck loads during head repositioning tasks. We performed a sensitivity analysis on the C5-C6 compression evaluated from a 24-degree freedom cervical spine model in OpenSim for static and dynamic movement trials. For static trials, we varied the magnitude of HSM, the position of its COM, and developed a novel stability constraint for static optimization. In dynamic trials, we varied HSM and the three principle MOIs. HSM magnitude and compression were linearly related to one another for both static and dynamic trials, with amplification factors varying between 1.9 and 3.9. Similar relationships were found for the COM position, although the relationship between C5-C6 peak compression and MOI in dynamic trials was generally nonlinear. This sensitivity analysis uncovered evidence in favour of hypotheses (i), (ii) and (iii). However, the model's prediction of C5-C6 compression was not overly sensitive to the magnitude of MOI. Therefore, the HSM mass properties may be more influential on neck compression than MOI properties, even during dynamic tasks.
MeSH term(s)	Neck/physiology ; Cervical Vertebrae ; Muscles ; Computer Simulation ; Biomechanical Phenomena
Language	English
Publishing date	2022-12-19
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	218076-5
ISSN	1873-2380 ; 0021-9290
ISSN (online)	1873-2380
ISSN	0021-9290
DOI	10.1016/j.jbiomech.2022.111416
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Zs.A 700: Show issues

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Article ; Online: Comparing Types of Yoga for Chronic Low Back and Neck Pain in Military Personnel: A Feasibility Randomized Controlled Trial.

Groessl, Erik J / Casteel, Danielle / McKinnon, Symone / McCarthy, Adhana / Schmalzl, Laura / Chang, Douglas G / Fowler, Ian M / Park, Crystal L

Global advances in health and medicine

2022 Volume 11, Page(s) 2164957X221094596

Abstract: Background: Chronic low back pain (cLBP) and chronic neck pain (cNP) are highly prevalent conditions and common reasons for disability among military personnel. Yoga and other mind-body interventions have been shown to safely decrease pain and ... ...

Abstract	Background: Chronic low back pain (cLBP) and chronic neck pain (cNP) are highly prevalent conditions and common reasons for disability among military personnel. Yoga and other mind-body interventions have been shown to safely decrease pain and disability in persons with cLBP and/or cNP but have not been adequately studied in active duty military personnel. The objective of this study was to examine the feasibility and acceptability of delivering 2 types of yoga (hatha and restorative) to a sample of active-duty military personnel with cLBP/cNP. Methods: Military personnel with cLBP and/or cNP (n = 49; 59% men) were randomized to either hatha or restorative yoga interventions. Interventions consisted of in-person yoga 1-2x weekly for 12 weeks. Feasibility and acceptability were measured by rates of recruitment, intervention attendance, attrition, adverse events, and satisfaction ratings. Health outcomes including pain and disability were measured at baseline, 12 weeks, and 6 months. Means and effect sizes are presented. Results: Recruitment was completed ahead of projections. Over 90% of participants agreed or strongly agreed that they enjoyed participation, liked the instructor, and would like to continue yoga. Retention rates were 86% and 80% at 12 week and 6 month assessments, respectively. Intervention attendance was adequate but lower than expected. There were small to moderate reductions in back-pain related disability, pain severity and pain interference, and improvements in quality of life, grip strength, and balance. In general, effects were larger for those who attended at least 50% of intervention classes. Participants with cNP tended to have smaller outcome improvements, but conclusions remain tentative given small sample sizes. Conclusions: Results demonstrate feasibility for conducting a randomized controlled comparative effectiveness trial of yoga for cLBP and cNP among active duty military personnel. Acceptability was also established. Ongoing work will enhance the intervention for cNP and establish feasibility at another military facility in preparation for a fully-powered comparative effectiveness trial.ClinicalTrials #NCT03504085; registered April 20, 2018.
Language	English
Publishing date	2022-06-16
Publishing country	United States
Document type	Journal Article
ZDB-ID	2709002-4
ISSN	2164-9561 ; 2164-9561
ISSN (online)	2164-9561
ISSN	2164-9561
DOI	10.1177/2164957X221094596
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