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Article ; Online: Spatiotemporal characteristics of soil erosion in a typical watershed consisting of different landscape: A case study of the Qin River Basin.

Li, Yanyan / Rong, Tianqi / Qin, Mingzhou / Zhang, Pengyan / Yang, Dan / Liu, Zhenyue / Zhang, Ying / Zhu, Hui / Song, Meiling

PloS one

2022 Volume 17, Issue 10, Page(s) e0275470

Abstract: ... of soil erosion intensity among different geographic environmental factors. The Qin River Basin is a geographical ... Universal Soil Loss Equation model to analyze the spatiotemporal changes in the soil-erosion intensity in the Qin River Basin ... environmental factors and different land use types. Results show that the soil erosion modulus of Qin River Basin were ...

Abstract	Soil erosion has a severe impact on habitat and productivity. It is considered to be a major environmental threat prevalent in ecosystems. However, few researchers have studied the spatial distribution of soil erosion intensity among different geographic environmental factors. The Qin River Basin is a geographical unit consisting of mountains, hills, and plains with significant regional characteristics, and it has a basin area of 14,810.91 km2. This study uses the Geographical Information Systems, Revised Universal Soil Loss Equation model to analyze the spatiotemporal changes in the soil-erosion intensity in the Qin River Basin from 1990 to 2018. Different environmental factors of land use, slope and altitude on erosion intensities of 19 secondary land types were analyzed. It can better reflect the soil erosion under different environmental factors and different land use types. Results show that the soil erosion modulus of Qin River Basin were 10.25 t hm-2 a-1, and it belong to slight erosion from 1990 to 2018. Soil erosion intensity is greater in grassland and woodland than in cropland. The strongest soil erosion occurred in the sparse forestland, and the lowest was in beach land. Soil erosion was the highest for a slope of 15~25° and an altitude of 1200~1500 m. Rainfall and slope are important factors lead to soil erosion, indicating weak water and soil conservation implemented in these areas. Therefore, priority should be given to these geomorphic units to formulate and implement soil-erosion control and ecological restoration policies in the Qin River Basin. This study provides a good reference for preventing and controlling soil erosion in river basins.
MeSH term(s)	China ; Conservation of Natural Resources ; Ecosystem ; Environmental Monitoring/methods ; Rivers ; Soil ; Soil Erosion ; Water
Chemical Substances	Soil ; Water (059QF0KO0R)
Language	English
Publishing date	2022-10-03
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2267670-3
ISSN	1932-6203 ; 1932-6203
ISSN (online)	1932-6203
ISSN	1932-6203
DOI	10.1371/journal.pone.0275470
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: An acoustical study of the qin.

Waltham, Chris / Lan, Yang / Koster, Evert

The Journal of the Acoustical Society of America

2016 Volume 139, Issue 4, Page(s) 1592

Abstract: The qin (guqin, chi'in) is a seven-string zither of ancient lineage that is prominent in Chinese ... replete with symbolism. The qin was associated with the Imperial aristocracy, and it remains an instrument ... of high culture. The qin is played with strings horizontal, and the soundbox is made in two halves ...

Abstract	The qin (guqin, chi'in) is a seven-string zither of ancient lineage that is prominent in Chinese musical culture. The qin's history is intertwined with philosophy and folklore and its construction is replete with symbolism. The qin was associated with the Imperial aristocracy, and it remains an instrument of high culture. The qin is played with strings horizontal, and the soundbox is made in two halves; the front is usually carved out of paulownia and the back is a flat plate of catalpa. There are two sound holes in the back. It appears that no acoustical study of the qin has been published hitherto. This paper describes vibroacoustic measurements on five examples, the analysis of which reveals the qin's basic sound radiation mechanisms. At low frequencies the qin shows beam bending and torsional modes with some coupling to air in the cavity. At higher frequencies the radiation is dominated by a dense spectrum of mixed cavity and wood modes; the cavity modes are described by a one-dimensional transmission matrix model.
Language	English
Publishing date	2016
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	219231-7
ISSN	1520-8524 ; 0001-4966
ISSN (online)	1520-8524
ISSN	0001-4966
DOI	10.1121/1.4944874
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Article ; Online: Huang Qin Decoction inhibits the initiation of experimental colitis associated carcinogenesis by controlling the PAD4 dependent NETs.

Pan, Zengfeng / Xie, Xuting / Chen, Yunliang / Pan, Simin / Wu, Zhiyun / Yang, Caiyi / Liang, Junjie / Zhang, Meilin / Wang, Qing / Chen, Jinyan / Zhou, Lian / Luo, Xia

Phytomedicine : international journal of phytotherapy and phytopharmacology

2022 Volume 107, Page(s) 154454

Abstract: ... Although Huang Qin Decoction (HQD) was found to be useful in treating UC and was used to gradually prevent and ... Conclusion: Huang Qin Decoction inhibits the initiation of colitis associated carcinogenesis by controlling ...

Abstract	Background: Colorectal cancer is associated with ulcerative colitis (UC). The infiltration of neutrophils is the main cause of DNA damage produced by inflammation in the intestinal epithelium. Under the action of peptidyl arginine deaminase 4 (PAD4), neutrophils dissociate chromatin and form neutrophil extracellular traps (NETs), which can aggravate tissue inflammation and encourage tumor development. Although Huang Qin Decoction (HQD) was found to be useful in treating UC and was used to gradually prevent and treat digestive tract cancers, the underlying reasons were unclear. Methods: To demonstrate HQD could inhibits the initiation of colitis associated carcinogenesis by controlling NETs related inflammation, we first performed an AOM/DSS-generated colitis-associated carcinogenesis model to assess the efficacy of HQD in reducing neutrophil infiltration and anti-tumor activity. Then, using network pharmacology research, we investigated the potential mechanisms underlying those medicinal effects, as demonstrated by the detection of NETs aggregation and PAD4 expression changes in the colon. Results: HQD substantially reduced the number of colon cancers and the expression of Ki67, restored the level of intestinal tight junction protein occludin and ZO-1, and relieved the intestinal inflammation caused by TNF-α, IL-1β. At the same time, it inhibited neutrophil infiltration in the colon and improved the immunosurveillance of CD8 Conclusion: Huang Qin Decoction inhibits the initiation of colitis associated carcinogenesis by controlling PAD4-dependent neutrophil extracellular traps.
MeSH term(s)	Animals ; Arginine/metabolism ; Carcinogenesis ; Chromatin/metabolism ; Colitis/chemically induced ; Colitis/complications ; Colitis/drug therapy ; Colitis, Ulcerative/chemically induced ; Colitis, Ulcerative/drug therapy ; Disease Models, Animal ; Extracellular Traps/metabolism ; Humans ; Inflammation/metabolism ; Ki-67 Antigen/metabolism ; Mice ; Mice, Inbred C57BL ; Occludin/metabolism ; Scutellaria baicalensis ; Tumor Necrosis Factor-alpha/metabolism
Chemical Substances	Chromatin ; Ki-67 Antigen ; Occludin ; Tumor Necrosis Factor-alpha ; Arginine (94ZLA3W45F)
Language	English
Publishing date	2022-09-11
Publishing country	Germany
Document type	Journal Article
ZDB-ID	1205240-1
ISSN	1618-095X ; 0944-7113
ISSN (online)	1618-095X
ISSN	0944-7113
DOI	10.1016/j.phymed.2022.154454
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Article: Xiang Qin Kang Gan Granules Treated the Human Coronavirus 229E Induced Pneumonia with Damp-Heat Syndrome in Mice.

Cao, Fang / Liu, Zhaoheng / Hao, Qingxun / Zhao, Ronghua / Bao, Lei / Cui, Xiaolan / Jiao, Yang

The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale

2022 Volume 2022, Page(s) 7609550

Abstract: Coronavirus disease 2019 (COVID-19), which causes severe respiratory illness, was first reported in Wuhan, China. The etiology of the disease is a new novel coronavirus named severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which was ... ...

Abstract	Coronavirus disease 2019 (COVID-19), which causes severe respiratory illness, was first reported in Wuhan, China. The etiology of the disease is a new novel coronavirus named severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which was reported to share the same origin as SARS-CoV, causing severe public health events in 2002. Unlike the SARS-CoV, which was conquered in the early summer of 2003, this virus was still contagious widely and reached a pandemic level. It can still spread fast even if the season's temperature is raised. Here, we made a model of pneumonia of human coronavirus 229E (HCoV-229E) with damp-heat syndrome treated by Xiangqin Kanggan granules to find a new medicine for treating these kinds of infectious diseases coronaviruses induced.
Language	English
Publishing date	2022-09-23
Publishing country	Egypt
Document type	Journal Article
ZDB-ID	1057056-1
ISSN	1712-9532 ; 1180-2332
ISSN	1712-9532 ; 1180-2332
DOI	10.1155/2022/7609550
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Article ; Online: The pattern, change and driven factors of vegetation cover in the Qin Mountains region.

Huang, Chenlu / Yang, Qinke / Guo, Yuhan / Zhang, Yongqiang / Guo, Linan

Scientific reports

2020 Volume 10, Issue 1, Page(s) 20591

Abstract: The Qin Mountains region is one of the most important climatic boundaries that divide the North and ... South of China. This study investigates vegetation covers changes across the Qin Mountains region over ... which were extracted from the Google Earth Engine (GEE). Our results show that the NDVI across the Qin ...

Abstract	The Qin Mountains region is one of the most important climatic boundaries that divide the North and South of China. This study investigates vegetation covers changes across the Qin Mountains region over the past three decades based on the Landsat-derived Normalized Difference Vegetation Index (NDVI), which were extracted from the Google Earth Engine (GEE). Our results show that the NDVI across the Qin Mountains have increased from 0.624 to 0.776 with annual change rates of 0.0053/a over the past 32 years. Besides, its abrupt point occurred in 2006 and the change rates after this point increased by 0.0094/a (R
Language	English
Publishing date	2020-11-25
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2615211-3
ISSN	2045-2322 ; 2045-2322
ISSN (online)	2045-2322
ISSN	2045-2322
DOI	10.1038/s41598-020-75845-5
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Article ; Online: Network pharmacology identification and in vivo validation of key pharmacological pathways of Qin Jiao for gout and arthritis

Xiaoxiong Yang / Yu Wang / Xueli Ding / Shanshan Ju / Xiaoye An / Bing Zhang / Zhijian Lin

Pharmaceutical Biology, Vol 61, Iss 1, Pp 1525-

2023 Volume 1535

Abstract: ... on patients, which might diminish quality of life. Qin Jiao, a perennial herb found in northwestern China and ... of Qin Jiao on gout and joint inflammation and elucidates its potential mechanism for gouty arthritis ... to assess the applications of Qin Jiao in arthritis treatment. Study 2 was performed to discover ...

Abstract	AbstractContext: Gout is a chronic disease that imposes a huge financial and health burden on patients, which might diminish quality of life. Qin Jiao, a perennial herb found in northwestern China and Japan, is commonly used for treating various ailments.Objective: This study investigates the effects of Qin Jiao on gout and joint inflammation and elucidates its potential mechanism for gouty arthritis.Materials and methods: Study 1, a literature review was conducted using PubMed, Web of Science, and CNKI to assess the applications of Qin Jiao in arthritis treatment. Study 2 was performed to discover the component targets and gouty disease targets via TCMSP, OMIM, GeneCards and DRUGBANK, and network pharmacology analysis. Study 3, male Sprague-Dawley (SD) rats were divided into normal, model, colchicine, Qin Jiao low-dose (QJL), and Qin Jiao high-dose group (QJH), oral gavage for 40 d. Serum, synovial fluid, and synovial membrane tissue were collected to measure the expression levels of IL-1β, IL-6, and STAT3.Results: The research also identified potential targets and pharmacological pathways of Qin Jiao for gout treatment. In vivo study demonstrated Qin Jiao can reduce IL-1β levels in serum and ankle flushing fluid. ELISA analysis confirmed that Qin Jiao significantly reduces the protein expression of IL-6 and STAT3.Discussion and conclusion: Qin Jiao exerts anti-inflammatory effects on gouty arthritis by modulating the IL-6/STAT3 pathway. This study provides a biological basis for the use of Qin Jiao in treating arthritis-related diseases and offers experimental evidence for potential future drug development.
Keywords	Joint inflammation ; Chinese herbs ; Kampo medicine ; IL-6/STAT3 pathway ; joint arthritis ; Therapeutics. Pharmacology ; RM1-950
Subject code	610
Language	English
Publishing date	2023-12-01T00:00:00Z
Publisher	Taylor & Francis Group
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: The Neglected Plant Resources in Chinese Archaeobotany: Revealing Animals’ Feed during the Pre-Qin Period Using the Flotation Results in Northern China

Tang, Liya / Yang, Anqi / Han, Kai

Agronomy. 2023 Aug. 22, v. 13, no. 9

2023

Abstract: ... the discussion of civilization development and social changes during the Pre-Qin period holds significant value ...

Abstract	The functions of non-agricultural crops unearthed from archaeological sites mainly pertain to their usage as livestock feed. However, the studies of livestock feed have predominantly relied on qualitative analysis, which often lacks descriptive objectivity and relies heavily on subjective feelings and experiences. In this paper, we aim to address this gap by focusing on quantitative analysis, utilizing macro-plant remains from the data of seventy-five archaeological settlements and one archaeological investigation in northern China spanning the Neolithic Age to the Bronze Age, as well as stable isotope analyses of carbon and nitrogen. This research delves into various aspects, including the exploration of the plant resources and livestock farming and the categorization of feed types for cattle and pigs in captivity. By employing quantitative analysis, we can gain a more comprehensive and objective understanding of these subjects. This approach aligns with studies on ancient livestock management and feed diversity. In essence, the discussion of civilization development and social changes during the Pre-Qin period holds significant value when considering forage analysis, just as crop analysis has proven insightful. By focusing on the quantitative analysis of non-agricultural crops and their role as livestock feed, we can shed light on important aspects of ancient societies and their agricultural practices.
Keywords	agronomy ; archaeobotany ; captive animals ; carbon ; cattle ; forage evaluation ; livestock feeds ; livestock husbandry ; nitrogen ; qualitative analysis ; quantitative analysis ; stable isotopes ; China
Language	English
Dates of publication	2023-0822
Publishing place	Multidisciplinary Digital Publishing Institute
Document type	Article ; Online
ZDB-ID	2607043-1
ISSN	2073-4395
ISSN	2073-4395
DOI	10.3390/agronomy13092191
Database	NAL-Catalogue (AGRICOLA)

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Article: Huang Qin Decoction inhibits the initiation of experimental colitis associated carcinogenesis by controlling the PAD4 dependent NETs

Pan, Zengfeng / Xie, Xuting / Chen, Yunliang / Pan, Simin / Wu, Zhiyun / Yang, Caiyi / Liang, Junjie / Zhang, Meilin / Wang, Qing / Chen, Jinyan / Zhou, Lian / Luo, Xia

Phytomedicine. 2022 Dec., v. 107

2022

Abstract: ... Qin Decoction (HQD) was found to be useful in treating UC and was used to gradually prevent and treat ... treatment. Huang Qin Decoction inhibits the initiation of colitis associated carcinogenesis by controlling ...

Abstract	Colorectal cancer is associated with ulcerative colitis (UC). The infiltration of neutrophils is the main cause of DNA damage produced by inflammation in the intestinal epithelium. Under the action of peptidyl arginine deaminase 4 (PAD4), neutrophils dissociate chromatin and form neutrophil extracellular traps (NETs), which can aggravate tissue inflammation and encourage tumor development. Although Huang Qin Decoction (HQD) was found to be useful in treating UC and was used to gradually prevent and treat digestive tract cancers, the underlying reasons were unclear. To demonstrate HQD could inhibits the initiation of colitis associated carcinogenesis by controlling NETs related inflammation, we first performed an AOM/DSS-generated colitis-associated carcinogenesis model to assess the efficacy of HQD in reducing neutrophil infiltration and anti-tumor activity. Then, using network pharmacology research, we investigated the potential mechanisms underlying those medicinal effects, as demonstrated by the detection of NETs aggregation and PAD4 expression changes in the colon. HQD substantially reduced the number of colon cancers and the expression of Ki67, restored the level of intestinal tight junction protein occludin and ZO-1, and relieved the intestinal inflammation caused by TNF-α, IL-1β. At the same time, it inhibited neutrophil infiltration in the colon and improved the immunosurveillance of CD8⁺T cells. The potential mechanisms of HQD intervention against UC and UC with neoplasia (UCN) were studied using network pharmacology, and 156 conjunct genes as well as numerous inflammation-related pathways were identified. Protein-protein interaction (PPI) analysis indicated that HQD inhibition of intestinal tumors might be related to the deactivation of PAD4, which was verified by the down-regulation of NETs, MPO-DNA complex levels, and PAD4 expression after HQD treatment. Huang Qin Decoction inhibits the initiation of colitis associated carcinogenesis by controlling PAD4-dependent neutrophil extracellular traps.
Keywords	DNA damage ; antineoplastic activity ; arginine ; carcinogenesis ; chromatin ; colon ; colorectal neoplasms ; digestive tract ; inflammation ; intestinal mucosa ; models ; neutrophils ; occludins ; protein-protein interactions ; tight junctions ; ulcerative colitis
Language	English
Dates of publication	2022-12
Publishing place	Elsevier GmbH
Document type	Article
ZDB-ID	1205240-1
ISSN	1618-095X ; 0944-7113
ISSN (online)	1618-095X
ISSN	0944-7113
DOI	10.1016/j.phymed.2022.154454
Database	NAL-Catalogue (AGRICOLA)

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Article: A Study on the Therapeutic Efficacy of San Zi Yang Qin Decoction for Non-Alcoholic Fatty Liver Disease and the Underlying Mechanism Based on Network Pharmacology.

Li, Yiping / Liu, Yang / Yang, Ming / Wang, Qianlei / Zheng, Yu / Xu, Jiaoya / Zheng, Peiyong / Song, Haiyan

Evidence-based complementary and alternative medicine : eCAM

2021 Volume 2021, Page(s) 8819245

Abstract: Objective: This study aims to explore the therapeutic efficacy of San Zi Yang Qin Decoction (SZ ...

Abstract	Objective: This study aims to explore the therapeutic efficacy of San Zi Yang Qin Decoction (SZ) and its potential mechanism in the treatment of non-alcoholic fatty liver disease (NAFLD) based on network pharmacology and Methods: Effective chemicals and targets of SZ were searched in online databases, according to the drug-likeness of compounds and the binomial distribution of targets. A disease-target-chemical network was established using NAFLD-associated genes screened through GeneCards database, Gene Ontology (GO) terms, and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways. Furthermore, animal experiments were conducted to verify the efficacy and mechanism of SZ predicted by network pharmacology. The NAFLD mouse model was established with C57BL/6J mice fed with a high-fat diet for 22 weeks. The mice in the control group were fed with a chow diet. From the 23 Results: A total of 27 effective compounds and 20 targets of SZ were screened. GO analysis uncovered a significant correlation between the targets of SZ and those of NAFLD. KEGG analysis presented the signaling pathways enriched in SZ and NAFLD, including NAFLD, TNF- Conclusions: According to the network pharmacology analysis and
Language	English
Publishing date	2021-01-08
Publishing country	United States
Document type	Journal Article
ZDB-ID	2171158-6
ISSN	1741-4288 ; 1741-427X
ISSN (online)	1741-4288
ISSN	1741-427X
DOI	10.1155/2021/8819245
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Article ; Online: The pattern, change and driven factors of vegetation cover in the Qin Mountains region

Chenlu Huang / Qinke Yang / Yuhan Guo / Yongqiang Zhang / Linan Guo

Scientific Reports, Vol 10, Iss 1, Pp 1-

2020 Volume 11

Abstract: Abstract The Qin Mountains region is one of the most important climatic boundaries that divide ... the North and South of China. This study investigates vegetation covers changes across the Qin Mountains ... the Qin Mountains have increased from 0.624 to 0.776 with annual change rates of 0.0053/a over the past 32 ...

Abstract	Abstract The Qin Mountains region is one of the most important climatic boundaries that divide the North and South of China. This study investigates vegetation covers changes across the Qin Mountains region over the past three decades based on the Landsat-derived Normalized Difference Vegetation Index (NDVI), which were extracted from the Google Earth Engine (GEE). Our results show that the NDVI across the Qin Mountains have increased from 0.624 to 0.776 with annual change rates of 0.0053/a over the past 32 years. Besides, its abrupt point occurred in 2006 and the change rates after this point increased by 0.0094/a (R2 = 0.8159, p < 0.01) (2006–2018), which is higher than that in 1987–1999 and 1999–2006. The mean NDVI have changed in different elevation ranges. The NDVI in the areas below 3300 m increased, such increased is especially most obviously in the cropland. Most of the forest and grassland locate above 3300 m with higher increased rate. Before 2006, the temperature and reference evapotranspiration (PET) were the important driven factors of NDVI change below 3300 m. After afforestation, human activities become important factors that influenced NDVI changes in the low elevation area, but hydro-climatic factors still play an important role in NDVI increase in the higher elevations area.
Keywords	Medicine ; R ; Science ; Q
Subject code	333
Language	English
Publishing date	2020-11-01T00:00:00Z
Publisher	Nature Portfolio
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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