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  1. Article ; Online: LiNAC100 contributes to linalool biosynthesis by directly regulating LiLiS in Lilium 'Siberia'.

    Liu, Xuping / Yan, Wenxin / Liu, Sijia / Wu, Jing / Leng, Pingsheng / Hu, Zenghui

    Planta

    2024  Volume 259, Issue 4, Page(s) 73

    Abstract: ... fragrance by directly regulating linalool synthase gene LiLiS. Lilium 'Siberia', an Oriental hybrid, is ... VIGS) of LiNAC100 was found to down-regulate the expression of linalool synthase gene (LiLiS) and ... activates LiLiS expression. Our findings reveal that LiNAC100 plays a key role in monoterpene biosynthesis ...

    Abstract Main conclusion: The transcription factor LiNAC100 has a novel function of regulating floral fragrance by directly regulating linalool synthase gene LiLiS. Lilium 'Siberia', an Oriental hybrid, is renowned as both a cut flower and garden plant, prized for its color and fragrance. The fragrance comprises volatile organic compounds (VOCs), primarily monoterpenes found in the plant. While the primary terpene synthases in Lilium 'Siberia' were identified, the transcriptional regulation of these terpene synthase (TPS) genes remains unclear. Thus, understanding the regulatory mechanisms of monoterpene biosynthesis is crucial for breeding flower fragrance, thereby improving ornamental and commercial values. In this study, we isolated a nuclear-localized LiNAC100 transcription factor from Lilium 'Siberia'. The virus-induced gene silencing (VIGS) of LiNAC100 was found to down-regulate the expression of linalool synthase gene (LiLiS) and significantly inhibit linalool synthesis. Conversely, transient overexpression of LiNAC100 produced opposite effects. Additionally, yeast one-hybrid and dual-luciferase assays confirmed that LiNAC100 directly activates LiLiS expression. Our findings reveal that LiNAC100 plays a key role in monoterpene biosynthesis in Lilium 'Siberia', promoting linalool synthesis through the activation of LiLiS expression. These results offer insights into the molecular mechanisms of terpene biosynthesis in Lilium 'Siberia' and open avenues for biotechnological enhancement of floral scent.
    MeSH term(s) Lilium/genetics ; Lilium/metabolism ; Gene Expression Regulation, Plant ; Plant Breeding ; Acyclic Monoterpenes/metabolism ; Monoterpenes/metabolism ; Flowers/genetics ; Transcription Factors/genetics
    Chemical Substances linalool (D81QY6I88E) ; Acyclic Monoterpenes ; Monoterpenes ; Transcription Factors
    Language English
    Publishing date 2024-02-23
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 208909-9
    ISSN 1432-2048 ; 0032-0935 ; 1866-2749
    ISSN (online) 1432-2048
    ISSN 0032-0935 ; 1866-2749
    DOI 10.1007/s00425-024-04340-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Bonn / Germany

    Z 46/303: Show issues

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  2. Article: Characterization and anti-aging activities of polysaccharide from

    Li, Yiping / Zhao, Xuyan / Wang, Jing / Yu, Qi / Ren, Jing / Jiang, Ziye / Jiao, Lili

    Frontiers in pharmacology

    2024  Volume 15, Page(s) 1370631

    Abstract: Introduction: ...

    Abstract Introduction:
    Language English
    Publishing date 2024-03-28
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2587355-6
    ISSN 1663-9812
    ISSN 1663-9812
    DOI 10.3389/fphar.2024.1370631
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Selectively extraction of astaxanthin from Haematococcus pluvialis by aqueous biphasic systems composed of ionic liquids and deep eutectic solutions.

    Zhang, Lili / Li, Yan / Gao, Jing

    Food chemistry

    2023  Volume 434, Page(s) 137399

    Abstract: Haematococcus pluvialis is rich in astaxanthin ester ( ... ...

    Abstract Haematococcus pluvialis is rich in astaxanthin ester (Ast
    Language English
    Publishing date 2023-09-09
    Publishing country England
    Document type Journal Article
    ZDB-ID 243123-3
    ISSN 1873-7072 ; 0308-8146
    ISSN (online) 1873-7072
    ISSN 0308-8146
    DOI 10.1016/j.foodchem.2023.137399
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Z 3634: Show issues

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  4. Article: Primary hyperparathyroidism: predictors of sporadic multi-gland disease.

    Yang, Lu / Jing, Xingguo / Pang, Hua / Guan, Lili / Li, Mengdan

    Endocrine connections

    2024  Volume 13, Issue 5

    Abstract: In this review, we discuss the definition, prevalence, and etiology of sporadic multiglandular disease (MGD), with an emphasis on its preoperative and intraoperative predictors. Primary hyperparathyroidism (PHPT) is the third-most common endocrine ... ...

    Abstract In this review, we discuss the definition, prevalence, and etiology of sporadic multiglandular disease (MGD), with an emphasis on its preoperative and intraoperative predictors. Primary hyperparathyroidism (PHPT) is the third-most common endocrine disorder, and multiglandular parathyroid disease (MGD) is a cause of PHPT. Hereditary MGD can be definitively diagnosed with detailed family history and genetic testing, whereas sporadic MGD presents a greater challenge in clinical practice, and parathyroidectomy for MGD is associated with a higher risk of surgical failure than single gland disease (SGD). Therefore, it is crucial to be able to predict the presence of sporadic MGD in a timely manner, either preoperatively or intraoperatively. Various predictive methods cannot accurately identify all cases of sporadic MGD, but they can greatly optimize the management of MGD diagnosis and treatment and optimize the cure rate. Future research will urge us to investigate more integrative predictive models as well as increase our understanding of MGD pathogenesis.
    Language English
    Publishing date 2024-04-04
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2668428-7
    ISSN 2049-3614
    ISSN 2049-3614
    DOI 10.1530/EC-23-0492
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: A Systematic Review of the Advances in the Study of T Lymphocyte Suppressor Receptors in HBV Infection: Potential Therapeutic Targets.

    Zhou, Daqiong / Liu, Lili / Liu, Jiangyu / Li, Hong / Zhang, Jing / Cao, Zhenhuan

    Journal of clinical medicine

    2024  Volume 13, Issue 5

    Abstract: Background: ...

    Abstract Background:
    Language English
    Publishing date 2024-02-21
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm13051210
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: The relationship between long non-coding gene

    Han, Lili / Liu, Jing / Shataer, Mireayi / Wu, Chengyong / Niyazi, Mayinuer

    Cancer biology & therapy

    2024  Volume 25, Issue 1, Page(s) 2322207

    Abstract: Background: CASC21: Methods: A total of 973 participants within 494 cervical cancer cases and 479 healthy controls were recruited. Five single nucleotide polymorphisms (SNPs) in the : Results: In the overall analysis, rs16902094 (: Conclusion: ... ...

    Abstract Background: CASC21
    Methods: A total of 973 participants within 494 cervical cancer cases and 479 healthy controls were recruited. Five single nucleotide polymorphisms (SNPs) in the
    Results: In the overall analysis, rs16902094 (
    Conclusion: Our finding firstly determined that two
    MeSH term(s) Female ; Humans ; Uterine Cervical Neoplasms/genetics ; Uterine Cervical Neoplasms/pathology ; Genetic Predisposition to Disease ; Carcinoma, Squamous Cell/genetics ; Genotype ; Polymorphism, Single Nucleotide ; Case-Control Studies ; China/epidemiology
    Language English
    Publishing date 2024-03-11
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2146305-0
    ISSN 1555-8576 ; 1538-4047
    ISSN (online) 1555-8576
    ISSN 1538-4047
    DOI 10.1080/15384047.2024.2322207
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5887: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  7. Article: Combination of immune checkpoint blockade and targeted gene regulation of angiogenesis for facilitating antitumor immunotherapy.

    Zhan, Jing / Zhang, Manli / Zhou, Lili / He, Chuan

    Frontiers in bioengineering and biotechnology

    2023  Volume 11, Page(s) 1065773

    Abstract: The rapid development of tumor immunotherapy has improved the management of patients with cancer. However, several key problems of tumor immunotherapy, including the insufficient activation of effector T cells, poor tumor invasion, and poor immune ... ...

    Abstract The rapid development of tumor immunotherapy has improved the management of patients with cancer. However, several key problems of tumor immunotherapy, including the insufficient activation of effector T cells, poor tumor invasion, and poor immune killing ability, lead to a low response rate. In the present study, a synergistic strategy was developed by combining
    Language English
    Publishing date 2023-03-13
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2719493-0
    ISSN 2296-4185
    ISSN 2296-4185
    DOI 10.3389/fbioe.2023.1065773
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  8. Article ; Online: On Cox proportional hazards model performance under different sampling schemes.

    Samawi, Hani / Yu, Lili / Yin, JingJing

    PloS one

    2023  Volume 18, Issue 4, Page(s) e0278700

    Abstract: Cox's proportional hazards model (PH) is an acceptable model for survival data analysis. This work investigates PH models' performance under different efficient sampling schemes for analyzing time to event data (survival data). We will compare a modified ...

    Abstract Cox's proportional hazards model (PH) is an acceptable model for survival data analysis. This work investigates PH models' performance under different efficient sampling schemes for analyzing time to event data (survival data). We will compare a modified Extreme, and Double Extreme Ranked Set Sampling (ERSS, and DERSS) schemes with a simple random sampling scheme. Observations are assumed to be selected based on an easy-to-evaluate baseline available variable associated with the survival time. Through intensive simulations, we show that these modified approaches (ERSS and DERSS) provide more powerful testing procedures and more efficient estimates of hazard ratio than those based on simple random sampling (SRS). We also showed theoretically that Fisher's information for DERSS is higher than that of ERSS, and ERSS is higher than SRS. We used the SEER Incidence Data for illustration. Our proposed methods are cost saving sampling schemes.
    MeSH term(s) Proportional Hazards Models ; Survival Analysis ; Research Design
    Language English
    Publishing date 2023-04-26
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2267670-3
    ISSN 1932-6203 ; 1932-6203
    ISSN (online) 1932-6203
    ISSN 1932-6203
    DOI 10.1371/journal.pone.0278700
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  9. Article ; Online: Gastric Fundus Splenosis.

    Jing, Lili / Cao, Qinghua / Li, Jun

    Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract

    2022  Volume 26, Issue 10, Page(s) 2239–2240

    MeSH term(s) Diagnosis, Differential ; Gastric Fundus/surgery ; Gastrointestinal Stromal Tumors/diagnosis ; Humans ; Splenectomy ; Splenosis/diagnostic imaging ; Splenosis/etiology
    Language English
    Publishing date 2022-04-20
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2012365-6
    ISSN 1873-4626 ; 1934-3213 ; 1091-255X
    ISSN (online) 1873-4626 ; 1934-3213
    ISSN 1091-255X
    DOI 10.1007/s11605-022-05327-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5207: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 354: Show issues

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  10. Article: A LAMP Assay for the Detection of

    Jiao, Jipeng / Ren, Lili / Chen, Rumin / Tao, Jing / Luo, Youqing

    Insects

    2022  Volume 13, Issue 6

    Abstract: Pine needle gall midge ( ...

    Abstract Pine needle gall midge (
    Language English
    Publishing date 2022-06-11
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662247-6
    ISSN 2075-4450
    ISSN 2075-4450
    DOI 10.3390/insects13060540
    Database MEDical Literature Analysis and Retrieval System OnLINE

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