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  1. Article ; Online: Clofazimine: A potential therapeutic option for severe COVID-19.

    Ateya, Areej Mohamed

    Medical hypotheses

    2021  Volume 150, Page(s) 110535

    MeSH term(s) COVID-19/drug therapy ; Clofazimine/therapeutic use ; Humans
    Chemical Substances Clofazimine (D959AE5USF)
    Language English
    Publishing date 2021-02-13
    Publishing country United States
    Document type Letter
    ZDB-ID 193145-3
    ISSN 1532-2777 ; 0306-9877
    ISSN (online) 1532-2777
    ISSN 0306-9877
    DOI 10.1016/j.mehy.2021.110535
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Zinc supplementation for males during COVID-19: Is it beneficial?

    Ateya, Areej Mohamed / Sabri, Nagwa A

    Medical hypotheses

    2020  Volume 146, Page(s) 110403

    MeSH term(s) COVID-19 ; Dietary Supplements ; Humans ; Male ; SARS-CoV-2 ; Zinc
    Chemical Substances Zinc (J41CSQ7QDS)
    Language English
    Publishing date 2020-11-20
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 193145-3
    ISSN 1532-2777 ; 0306-9877
    ISSN (online) 1532-2777
    ISSN 0306-9877
    DOI 10.1016/j.mehy.2020.110403
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Angiotensin-converting enzyme inhibitors and angiotensin-receptor blockers benefits outweigh the risks in COVID-19 hypertensive patients.

    Ateya, Areej Mohamed / Sabri, Nagwa A

    Journal of medical virology

    2020  Volume 93, Issue 4, Page(s) 1873–1874

    MeSH term(s) Angiotensin Receptor Antagonists/adverse effects ; Angiotensin-Converting Enzyme Inhibitors/adverse effects ; Angiotensins ; COVID-19 ; Humans ; Hypertension/drug therapy ; Hypertension/epidemiology ; Renin-Angiotensin System ; SARS-CoV-2
    Chemical Substances Angiotensin Receptor Antagonists ; Angiotensin-Converting Enzyme Inhibitors ; Angiotensins
    Keywords covid19
    Language English
    Publishing date 2020-11-22
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 752392-0
    ISSN 1096-9071 ; 0146-6615
    ISSN (online) 1096-9071
    ISSN 0146-6615
    DOI 10.1002/jmv.26672
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Angiotensin-converting enzyme inhibitors (ACEIs) and Angiotensin-receptor blockers (ARBs) benefits outweigh the risks in COVID-19 hypertensive patients

    Ateya, Areej Mohamed / Sabri, Nagwa A

    J. med. virol

    Abstract: We read with interest the article published by Wang et al. in Medical Virology journal This article is protected by copyright. All rights reserved. ...

    Abstract We read with interest the article published by Wang et al. in Medical Virology journal This article is protected by copyright. All rights reserved.
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #927840
    Database COVID19

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  5. Article ; Online: Effects of Ramipril on Biomarkers of Endothelial Dysfunction and Inflammation in Hypertensive Children on Maintenance Hemodialysis: the SEARCH Randomized Placebo-Controlled Trial.

    Ateya, Areej Mohamed / El Hakim, Ihab / Shahin, Sara Mahmoud / El Borolossy, Radwa / Kreutz, Reinhold / Sabri, Nagwa Ali

    Hypertension (Dallas, Tex. : 1979)

    2022  Volume 79, Issue 8, Page(s) 1856–1865

    Abstract: Background: Hypertension, endothelial dysfunction, and inflammation are associated with increased cardiovascular mortality in end-stage kidney disease. We evaluated the effects of ACE (angiotensin-converting enzyme) inhibition on biomarkers of ... ...

    Abstract Background: Hypertension, endothelial dysfunction, and inflammation are associated with increased cardiovascular mortality in end-stage kidney disease. We evaluated the effects of ACE (angiotensin-converting enzyme) inhibition on biomarkers of endothelial dysfunction and inflammation in hypertensive children with end-stage kidney disease on maintenance hemodialysis.
    Methods: In a randomized, double-blind, placebo-controlled trial, 135 (72 males/63 females) children and adolescents (age 7-15 years) were randomly assigned to treatment with either 2.5 mg once daily ramipril (n=68) or placebo (n=67) for 16 weeks. Primary outcome were the serum concentrations of asymmetrical dimethylarginine, a marker of endothelial dysfunction and hs-CRP (high-sensitivity C-reactive protein), a marker of inflammation. Changes in IL-6 (interleukin-6), TNF-α (tumor necrosis factor-alpha), systolic (S), and diastolic (D) blood pressure were secondary outcomes. Change in potassium levels and incidence of hyperkalemia were among the safety parameters.
    Results: Ramipril, but not placebo, significantly reduced serum levels of asymmetrical dimethylarginine (-79.6%;
    Conclusions: Ramipril improves biomarkers of endothelial dysfunction and inflammation in hypertensive children on maintenance hemodialysis in addition to its efficacious and safe potential to lower blood pressure.
    Registration: URL: https://www.
    Clinicaltrials: gov; Unique identifier: NCT04582097.
    MeSH term(s) Adolescent ; Antihypertensive Agents/pharmacology ; Antihypertensive Agents/therapeutic use ; Biomarkers ; Blood Pressure ; C-Reactive Protein ; Child ; Double-Blind Method ; Female ; Humans ; Hyperkalemia ; Hypertension/drug therapy ; Inflammation ; Interleukin-6/pharmacology ; Kidney Failure, Chronic/complications ; Kidney Failure, Chronic/therapy ; Male ; Ramipril/pharmacology ; Ramipril/therapeutic use ; Renal Dialysis ; Tumor Necrosis Factor-alpha/pharmacology
    Chemical Substances Antihypertensive Agents ; Biomarkers ; Interleukin-6 ; Tumor Necrosis Factor-alpha ; C-Reactive Protein (9007-41-4) ; Ramipril (L35JN3I7SJ)
    Language English
    Publishing date 2022-06-10
    Publishing country United States
    Document type Journal Article ; Randomized Controlled Trial ; Research Support, Non-U.S. Gov't
    ZDB-ID 423736-5
    ISSN 1524-4563 ; 0194-911X ; 0362-4323
    ISSN (online) 1524-4563
    ISSN 0194-911X ; 0362-4323
    DOI 10.1161/HYPERTENSIONAHA.122.19312
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Effect of Omega-3 Fatty Acids on Serum Lipid Profile and Oxidative Stress in Pediatric Patients on Regular Hemodialysis: A Randomized Placebo-Controlled Study.

    Ateya, Areej Mohamed / Sabri, Nagwa Ali / El Hakim, Ihab / Shaheen, Sara M

    Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation

    2017  Volume 27, Issue 3, Page(s) 169–174

    Abstract: Objective: We sought to evaluate the effects of omega-3 fatty acids supplementation on serum lipid profile and oxidative stress markers in pediatric patients with end-stage renal disease on regular hemodialysis (HD).: Design: This study was a double- ... ...

    Abstract Objective: We sought to evaluate the effects of omega-3 fatty acids supplementation on serum lipid profile and oxidative stress markers in pediatric patients with end-stage renal disease on regular hemodialysis (HD).
    Design: This study was a double-blinded, randomized, placebo-controlled trial conducted on 49 pediatric patients on regular HD for at least 6 months.
    Intervention: Patients were randomly divided into either omega-3 group (n = 25) who received 1-g oral omega-3 capsule once daily for 16 weeks or placebo group (n = 24) who received 1-g matching oral placebo capsule once daily for 16 weeks.
    Main outcome measure: Lipid profile markers including: total cholesterol, triglycerides, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, and oxidative stress markers including the following: malondialdehyde, glutathione peroxidase, and superoxide dismutase were measured at baseline and after 16 weeks of supplementation.
    Results: By the end of the study, children in omega-3 group showed a highly significant reduction in total cholesterol and a highly significant increase in glutathione peroxidase and superoxide dismutase levels.
    Conclusion: The administration of omega-3 has a beneficial effect on serum lipid profile and oxidative stress in children undergoing HD.
    MeSH term(s) Adolescent ; Biomarkers/blood ; Child ; Cholesterol, HDL/blood ; Cholesterol, LDL/blood ; Dietary Supplements ; Double-Blind Method ; Fatty Acids, Omega-3/administration & dosage ; Female ; Glutathione Peroxidase/blood ; Humans ; Kidney Failure, Chronic/blood ; Kidney Failure, Chronic/drug therapy ; Male ; Malondialdehyde/blood ; Oxidative Stress/drug effects ; Prospective Studies ; Renal Dialysis ; Superoxide Dismutase/blood ; Triglycerides/blood
    Chemical Substances Biomarkers ; Cholesterol, HDL ; Cholesterol, LDL ; Fatty Acids, Omega-3 ; Triglycerides ; Malondialdehyde (4Y8F71G49Q) ; Glutathione Peroxidase (EC 1.11.1.9) ; Superoxide Dismutase (EC 1.15.1.1)
    Language English
    Publishing date 2017-05
    Publishing country United States
    Document type Journal Article ; Randomized Controlled Trial
    ZDB-ID 1080003-7
    ISSN 1532-8503 ; 1051-2276
    ISSN (online) 1532-8503
    ISSN 1051-2276
    DOI 10.1053/j.jrn.2016.11.005
    Database MEDical Literature Analysis and Retrieval System OnLINE

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