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  1. Article ; Online: Reply by Xu

    Xu, Yonghao / Liu, Xiaoqing / Xu, Zhiheng / Zhong, Nanshan / Li, Yimin

    American journal of respiratory and critical care medicine

    2020  Volume 202, Issue 4, Page(s) 631–632

    MeSH term(s) Betacoronavirus ; COVID-19 ; Coronavirus Infections ; Humans ; Pandemics ; Pneumonia, Viral ; Respiration, Artificial ; Respiratory Distress Syndrome ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-06-22
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 1180953-x
    ISSN 1535-4970 ; 0003-0805 ; 1073-449X
    ISSN (online) 1535-4970
    ISSN 0003-0805 ; 1073-449X
    DOI 10.1164/rccm.202005-1841LE
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Uh II Zs.80: Show issues Location:
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  2. Article: Mechanism of Xu Li's Experiential Prescription for the Treatment of EGFR-Positive NSCLC.

    Xu, Bin / Zhang, Haitao / Wang, Yuchao / Huang, Shuran / Xu, Li

    Evidence-based complementary and alternative medicine : eCAM

    2020  Volume 2020, Page(s) 8787153

    Abstract: ... the human health. Xu Li's experiential prescription (XLEP) can treat the NSCLC. However, whether XLEP can regulate ...

    Abstract The non-small-cell lung cancer (NSCLC) is the most common lung cancer which seriously threatens the human health. Xu Li's experiential prescription (XLEP) can treat the NSCLC. However, whether XLEP can regulate the autophagy in the EGFR-positive NSCLC still remains unknown. We found that the cellular activity of drug-resistant cells and sensitive cells were all decreased in the TCM group and TCM + Gef group. The expression of autophagy-associated proteins (mTOR and Beclin1-Vps34) in drug-resistant cells was decreased in the TCM group, while the expression of autophagy-associated proteins in sensitive cells was all decreased in the TCM + Gef group. The ratio of M1/M2 macrophages was increased when IL-4-induced RAW264.7 was treated with TCM. TCM treatment promoted the expression of CCL2 and CCL3 while it downregulated the CCL22 level among A549, H1975, and PC9 cells. The expression of TNF-
    Language English
    Publishing date 2020-03-12
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2171158-6
    ISSN 1741-4288 ; 1741-427X
    ISSN (online) 1741-4288
    ISSN 1741-427X
    DOI 10.1155/2020/8787153
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5995: Show issues Location:
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  4. Article: Xiao-Xu-Ming

    Wang, Yue-Hua / Yang, Ying-Lin / Cheng, Xiao / Zhang, Jun / Li, Wan / Du, Guan-Hua

    Neural regeneration research

    2018  Volume 14, Issue 3, Page(s) 470–479

    Abstract: Xiao-Xu-Ming decoction has been widely used to treat stroke and sequelae of stroke. We have ... previously shown that the active fractions of Xiao-Xu-Ming decoction attenuate cerebral ischemic injury ... However, the global protein profile and signaling conduction pathways regulated by Xiao-Xu-Ming decoction are still ...

    Abstract Xiao-Xu-Ming decoction has been widely used to treat stroke and sequelae of stroke. We have previously shown that the active fractions of Xiao-Xu-Ming decoction attenuate cerebral ischemic injury. However, the global protein profile and signaling conduction pathways regulated by Xiao-Xu-Ming decoction are still unclear. This study established a two-vessel occlusion rat model by bilateral common carotid artery occlusion. Rats were intragastrically administered 50 or 150 mg/kg Xiao-Xu-Ming decoction for 4 consecutive weeks. Learning and memory abilities were measured with Morris water maze. Motor ability was detected with prehensile test. Coordination ability was examined using the inclined screen test. Neuronal plasticity was observed by immunofluorescent staining. Differentially expressed proteins of rat hippocampus were analyzed by label-free quantitative proteomics. Real time-polymerase chain reaction and western blot assay were used to identify the changes in proteins. Results showed that Xiao-Xu-Ming decoction dramatically alleviated learning and memory deficits, and motor and coordination dysfunction, and increased the expression of microtubule-associated protein 2. Xiao-Xu-Ming decoction extract remarkably decreased 13 upregulated proteins and increased 39 downregulated proteins. The regulated proteins were mainly involved in oxidation reduction process, intracellular signaling cascade process, and protein catabolic process. The signaling pathways were mainly involved in ubiquitin mediated proteolysis and the phosphatidylinositol signaling system. Furthermore, there was an interaction among Rab2a, Ptpn1, Ppm1e, Cdk18, Gorasp2, Eps15, Capza2, Syngap1 and Mt-nd1. Protein analyses confirmed the changes in expression of MT-ND1. The current findings provide new insights into the molecular mechanisms of Xiao-Xu-Ming decoction extract's effects on chronic cerebral hypoperfusion.
    Language English
    Publishing date 2018-12-14
    Publishing country India
    Document type Journal Article
    ZDB-ID 2388460-5
    ISSN 1876-7958 ; 1673-5374
    ISSN (online) 1876-7958
    ISSN 1673-5374
    DOI 10.4103/1673-5374.245471
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Morphology of the preadult stages of Coronaproctus castanopsis Li, Xu & Wu (Hemiptera: Coccomorpha: Monophlebidae).

    Zheng, Xinyi / Li, Jiani / Wu, Sanan

    Zootaxa

    2023  Volume 5352, Issue 4, Page(s) 537–552

    Abstract: All the preadult stages of Coronaproctus castanopsis Li, Xu & Wu, 2023 are described and ...

    Abstract All the preadult stages of Coronaproctus castanopsis Li, Xu & Wu, 2023 are described and illustrated (first- and second-instar nymphs, third-instar male and female nymphs, and the male pupa), based on material from Zhejiang Province, China. A key to separate the developmental stages is provided.
    MeSH term(s) Female ; Male ; Animals ; Hemiptera/anatomy & histology ; Nymph/anatomy & histology ; Pupa ; Fagaceae
    Language English
    Publishing date 2023-10-05
    Publishing country New Zealand
    Document type Journal Article
    ISSN 1175-5334
    ISSN (online) 1175-5334
    DOI 10.11646/zootaxa.5352.4.5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: The clinical efficacy of Zuqing Xu "Wuduling" powder for snake injury on the swelling of the affected limb bitten by Agkistrodon

    Ye, Jingjing / Qian, Wei / Chen, Ninggang / Hu, Zhikai / Ye, Shu / Li, Mei / Zhang, Lian / Wang, Hui / Lu, Yanwu

    Biotechnology & genetic engineering reviews

    2023  , Page(s) 1–18

    Abstract: To determine the clinical efficacy of Zuqing Xu 'Wuduling' powder for snake injury on the swelling ...

    Abstract To determine the clinical efficacy of Zuqing Xu 'Wuduling' powder for snake injury on the swelling of the affected limb bitten by
    Language English
    Publishing date 2023-03-22
    Publishing country England
    Document type Journal Article
    ZDB-ID 49457-4
    ISSN 2046-5556 ; 0264-8725
    ISSN (online) 2046-5556
    ISSN 0264-8725
    DOI 10.1080/02648725.2023.2191085
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

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  7. Article ; Online: Mechanistic study on the side arm effect in a palladium/Xu-Phos-catalyzed enantioselective alkoxyalkenylation of γ-hydroxyalkenes.

    Zhu, Shuai / Ye, Zihao / Chen, Ming-Jie / Wang, Lei / Wang, Yu-Zhuo / Zhang, Ke-Nan / Li, Wen-Bo / Ding, Han-Ming / Li, Zhiming / Zhang, Junliang

    Nature communications

    2023  Volume 14, Issue 1, Page(s) 7611

    Abstract: ... identified Xu-Phos (Xu8 and Xu9) with a suitable side-arm adjacent to the PCy ...

    Abstract Recently, the asymmetric bifunctionalization of alkenes has received much attention. However, the development of enantioselective alkoxyalkenylation has posed a considerable challenge and has lagged largely behind. Herein, we report a new palladium-catalyzed enantioselective alkoxyalkenylation reaction, using a range of primary, secondary, and tertiary γ-hydroxy-alkenes with alkenyl halides. By employing newly identified Xu-Phos (Xu8 and Xu9) with a suitable side-arm adjacent to the PCy
    Language English
    Publishing date 2023-11-22
    Publishing country England
    Document type Journal Article
    ZDB-ID 2553671-0
    ISSN 2041-1723 ; 2041-1723
    ISSN (online) 2041-1723
    ISSN 2041-1723
    DOI 10.1038/s41467-023-43202-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Corrigendum: Detecting key functional components group and speculating the potential mechanism of Xiao-Xu-Ming decoction in treating stroke.

    Chen, Yu-Peng / Wang, Ke-Xin / Cai, Jie-Qi / Li, Yi / Yu, Hai-Lang / Wu, Qi / Meng, Wei / Wang, Han-Duo / Yin, Chuan-Hui / Wu, Jie / Huang, Mian-Bo / Li, Rong / Guan, Dao-Gang

    Frontiers in cell and developmental biology

    2023  Volume 10, Page(s) 1107236

    Abstract: This corrects the article DOI: 10.3389/fcell.2022.753425.]. ...

    Abstract [This corrects the article DOI: 10.3389/fcell.2022.753425.].
    Language English
    Publishing date 2023-01-20
    Publishing country Switzerland
    Document type Published Erratum
    ZDB-ID 2737824-X
    ISSN 2296-634X
    ISSN 2296-634X
    DOI 10.3389/fcell.2022.1107236
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Pd/Xu-Phos-catalyzed asymmetric elimination of fully substituted enol triflates into axially chiral trisubstituted allenes.

    Han, Jie / Liu, Siyuan / Wang, Huanan / Wang, Jie / Qian, Hui / Li, Zhiming / Ma, Shengming / Zhang, Junliang

    Science advances

    2023  Volume 9, Issue 11, Page(s) eadg1002

    Abstract: The β-H elimination, as one of the most important elementary reactions in transition metal chemistry, is a key step in quenching the carbon-palladium bond for the Heck reaction. However, the β-H elimination of the alkenyl palladium species leading to ... ...

    Abstract The β-H elimination, as one of the most important elementary reactions in transition metal chemistry, is a key step in quenching the carbon-palladium bond for the Heck reaction. However, the β-H elimination of the alkenyl palladium species leading to allene is an energetically unfavored process, and therefore, it has been a long-standing challenge in control of this process via enantioselective manner. We developed a concise and efficient methodology to construct trisubstituted chiral allenes from stereodefined fully substituted enol triflates by the enantioselective β
    Language English
    Publishing date 2023-03-17
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2810933-8
    ISSN 2375-2548 ; 2375-2548
    ISSN (online) 2375-2548
    ISSN 2375-2548
    DOI 10.1126/sciadv.adg1002
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Letter by Xu et al Regarding Article, "Impact of Infection on the Risk of Recurrent Stroke Among Patients With Acute Ischemic Stroke".

    Xu, Zongliang / Xu, Gelin / Li, Junrong

    Stroke

    2020  Volume 51, Issue 12, Page(s) e365

    MeSH term(s) Brain Ischemia/epidemiology ; Cerebral Infarction ; Humans ; Ischemic Stroke ; Stroke/epidemiology
    Language English
    Publishing date 2020-11-23
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 80381-9
    ISSN 1524-4628 ; 0039-2499 ; 0749-7954
    ISSN (online) 1524-4628
    ISSN 0039-2499 ; 0749-7954
    DOI 10.1161/STROKEAHA.120.031795
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

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