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  1. Article: beta-Phenylethylamines and the isoquinoline alkaloids.

    Bentley, Kenneth W

    Natural product reports

    2006  Volume 23, Issue 3, Page(s) 444–463

    MeSH term(s) Alkaloids ; Isoquinolines ; Molecular Structure ; Phenethylamines ; Plants, Medicinal/chemistry
    Chemical Substances Alkaloids ; Isoquinolines ; Phenethylamines
    Language English
    Publishing date 2006-06
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2002546-4
    ISSN 1460-4752 ; 0265-0568
    ISSN (online) 1460-4752
    ISSN 0265-0568
    DOI 10.1039/b509523a
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: beta-Phenylethylamines and the isoquinoline alkaloids.

    Bentley, Kenneth W

    Natural product reports

    2005  Volume 22, Issue 2, Page(s) 249–268

    Abstract: This review covers beta-phenylethylamines and isoquinoline alkaloids derived from them, including further products of oxidation, condensation with formaldehyde and rearrangement, some of which do not contain as isoquinoline system, together with ... ...

    Abstract This review covers beta-phenylethylamines and isoquinoline alkaloids derived from them, including further products of oxidation, condensation with formaldehyde and rearrangement, some of which do not contain as isoquinoline system, together with napthylisoquinoline alkaloids, which have a different biogenetic origin. The occurrence of the alkaloids with the structures of new bases, together with their reactions and syntheses, are reported. The literature from July 2003 to June 2004 is reviewed, with 145 references cited.
    MeSH term(s) Alkaloids ; Isoquinolines ; Molecular Structure ; Phenethylamines ; Plants, Medicinal/chemistry
    Chemical Substances Alkaloids ; Isoquinolines ; Phenethylamines
    Language English
    Publishing date 2005-04
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2002546-4
    ISSN 1460-4752 ; 0265-0568
    ISSN (online) 1460-4752
    ISSN 0265-0568
    DOI 10.1039/b316108k
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Review of wearable technologies and machine learning methodologies for systematic detection of mild traumatic brain injuries.

    Schmid, William / Fan, Yingying / Chi, Taiyun / Golanov, Eugene / Regnier-Golanov, Angelique S / Austerman, Ryan J / Podell, Kenneth / Cherukuri, Paul / Bentley, Timothy / Steele, Christopher T / Schodrof, Sarah / Aazhang, Behnaam / Britz, Gavin W

    Journal of neural engineering

    2021  Volume 18, Issue 4

    Abstract: Mild traumatic brain injuries (mTBIs) are the most common type of brain injury. Timely diagnosis of mTBI is crucial in making 'go/no-go' decision in order to prevent repeated injury, avoid strenuous activities which may prolong recovery, and assure ... ...

    Abstract Mild traumatic brain injuries (mTBIs) are the most common type of brain injury. Timely diagnosis of mTBI is crucial in making 'go/no-go' decision in order to prevent repeated injury, avoid strenuous activities which may prolong recovery, and assure capabilities of high-level performance of the subject. If undiagnosed, mTBI may lead to various short- and long-term abnormalities, which include, but are not limited to impaired cognitive function, fatigue, depression, irritability, and headaches. Existing screening and diagnostic tools to detect acute and
    MeSH term(s) Brain Concussion ; Brain Injuries ; Humans ; Machine Learning ; Sensitivity and Specificity ; Wearable Electronic Devices
    Language English
    Publishing date 2021-08-19
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2170901-4
    ISSN 1741-2552 ; 1741-2560
    ISSN (online) 1741-2552
    ISSN 1741-2560
    DOI 10.1088/1741-2552/ac1982
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: beta-Phenylethylamines and the isoquinoline alkaloids.

    Bentley, Kenneth W

    Natural product reports

    2004  Volume 21, Issue 3, Page(s) 395–424

    Abstract: This review covers beta-phenylethylamines and isoquinoline alkaloids derived from them, including further products of oxidation. condensation with formaldehyde and rearrangement, some of which do not contain an isoquinoline system, together with ... ...

    Abstract This review covers beta-phenylethylamines and isoquinoline alkaloids derived from them, including further products of oxidation. condensation with formaldehyde and rearrangement, some of which do not contain an isoquinoline system, together with naphthylisoquinoline alkaloids, which have a different biogenetic origin. The occurrence of the alkaloids, with the structures of new bases, together with their reactions, syntheses and biological activities are reported. The literature from July 2002 to June 2003 is reviewed, with 568 references cited.
    MeSH term(s) Alkaloids ; Aniline Compounds ; Isoquinolines ; Molecular Structure ; Plants, Medicinal/chemistry
    Chemical Substances Alkaloids ; Aniline Compounds ; Isoquinolines
    Language English
    Publishing date 2004-06
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2002546-4
    ISSN 1460-4752 ; 0265-0568
    ISSN (online) 1460-4752
    ISSN 0265-0568
    DOI 10.1039/b212259f
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Beta-phenylethylamines and the isoquinoline alkaloids.

    Bentley, Kenneth W

    Natural product reports

    2003  Volume 20, Issue 3, Page(s) 342–365

    Abstract: This review covers beta-phenylethylamines and isoquinoline alkaloids and compounds derived from them, including further products of oxidation, condensation with formaldehyde and rearrangement, some of which do not contain an isoquinoline system, together ...

    Abstract This review covers beta-phenylethylamines and isoquinoline alkaloids and compounds derived from them, including further products of oxidation, condensation with formaldehyde and rearrangement, some of which do not contain an isoquinoline system, together with naphthylisoquinoline alkaloids, which have a different biogenetic origin. The occurrence of the alkaloids, with the structures of new bases, together with their reactions, syntheses and biological activities are reported. The literature from July 2001 to June 2002 is reviewed, with 581 references cited.
    MeSH term(s) Alkaloids ; Isoquinolines ; Molecular Structure ; Phenethylamines ; Plants, Medicinal/chemistry
    Chemical Substances Alkaloids ; Isoquinolines ; Phenethylamines
    Language English
    Publishing date 2003-06-10
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2002546-4
    ISSN 1460-4752 ; 0265-0568
    ISSN (online) 1460-4752
    ISSN 0265-0568
    DOI 10.1039/b111626f
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Beta-phenylethylamines and the isoquinoline alkaloids.

    Bentley, Kenneth W

    Natural product reports

    2002  Volume 19, Issue 3, Page(s) 332–356

    Abstract: This review covers beta-phenylethylamines and isoquinoline alkaloids that are derived from them, including further products of oxidation, condensation with formaldehyde and rearrangement, some of which do not contain an isoquinoline system, together with ...

    Abstract This review covers beta-phenylethylamines and isoquinoline alkaloids that are derived from them, including further products of oxidation, condensation with formaldehyde and rearrangement, some of which do not contain an isoquinoline system, together with naphthylisoquinoline alkaloids, which have a different biogenetic origin. The occurrence of the alkaloids, with the structures of new bases, together with their reactions, syntheses and biological activities are reported. The literature from July 2000 to June 2001 is reviewed, with 495 references cited.
    MeSH term(s) Alkaloids ; Isoquinolines ; Molecular Structure ; Phenethylamines ; Plants, Medicinal/chemistry
    Chemical Substances Alkaloids ; Isoquinolines ; Phenethylamines
    Language English
    Publishing date 2002-07-23
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2002546-4
    ISSN 1460-4752 ; 0265-0568
    ISSN (online) 1460-4752
    ISSN 0265-0568
    DOI 10.1039/b009713f
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: β-Phenylethylamines and the isoquinoline alkaloids

    Bentley, Kenneth W.

    Natural product reports. 2003 June 20, v. 20, no. 3

    2003  

    Abstract: This review covers β-phenylethylamines and isoquinoline alkaloids and compounds derived from them, including further products of oxidation, condensation with formaldehyde and rearrangement, some of which do not contain an isoquinoline system, together ... ...

    Abstract This review covers β-phenylethylamines and isoquinoline alkaloids and compounds derived from them, including further products of oxidation, condensation with formaldehyde and rearrangement, some of which do not contain an isoquinoline system, together with naphthylisoquinoline alkaloids, which have a different biogenetic origin. The occurrence of the alkaloids, with the structures of new bases, together with their reactions, syntheses and biological activities are reported. The literature from July 2001 to June 2002 is reviewed, with 581 references cited.
    Keywords bioactive properties ; formaldehyde ; isoquinoline alkaloids ; oxidation
    Language English
    Dates of publication 2003-0620
    Size p. 342-365.
    Publishing place The Royal Society of Chemistry
    Document type Article
    ZDB-ID 2002546-4
    ISSN 1460-4752 ; 0265-0568
    ISSN (online) 1460-4752
    ISSN 0265-0568
    DOI 10.1039/b111626f
    Database NAL-Catalogue (AGRICOLA)

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  8. Article: β-Phenylethylamines and the isoquinoline alkaloids

    Bentley, Kenneth W.

    Natural product reports. 2002 May 23, v. 19, no. 3

    2002  

    Abstract: This review covers β-phenylethylamines and isoquinoline alkaloids that are derived from them, including further products of oxidation, condensation with formaldehyde and rearrangement, some of which do not contain an isoquinoline system, together with ... ...

    Abstract This review covers β-phenylethylamines and isoquinoline alkaloids that are derived from them, including further products of oxidation, condensation with formaldehyde and rearrangement, some of which do not contain an isoquinoline system, together with naphthylisoquinoline alkaloids, which have a different biogenetic origin. The occurrence of the alkaloids, with the structures of new bases, together with their reactions, syntheses and biological activities are reported. The literature from July 2000 to June 2001 is reviewed, with 495 references cited.
    Keywords bioactive properties ; formaldehyde ; isoquinoline alkaloids ; oxidation
    Language English
    Dates of publication 2002-0523
    Size p. 332-356.
    Publishing place The Royal Society of Chemistry
    Document type Article
    ZDB-ID 2002546-4
    ISSN 1460-4752 ; 0265-0568
    ISSN (online) 1460-4752
    ISSN 0265-0568
    DOI 10.1039/b009713f
    Database NAL-Catalogue (AGRICOLA)

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  9. Article ; Online: Accelerating Precision Drug Development and Drug Repurposing by Leveraging Human Genetics.

    Pulley, Jill M / Shirey-Rice, Jana K / Lavieri, Robert R / Jerome, Rebecca N / Zaleski, Nicole M / Aronoff, David M / Bastarache, Lisa / Niu, Xinnan / Holroyd, Kenneth J / Roden, Dan M / Skaar, Eric P / Niswender, Colleen M / Marnett, Lawrence J / Lindsley, Craig W / Ekstrom, Leeland B / Bentley, Alan R / Bernard, Gordon R / Hong, Charles C / Denny, Joshua C

    Assay and drug development technologies

    2017  Volume 15, Issue 3, Page(s) 113–119

    Abstract: The potential impact of using human genetic data linked to longitudinal electronic medical records on drug development is extraordinary; however, the practical application of these data necessitates some organizational innovations. Vanderbilt has created ...

    Abstract The potential impact of using human genetic data linked to longitudinal electronic medical records on drug development is extraordinary; however, the practical application of these data necessitates some organizational innovations. Vanderbilt has created resources such as an easily queried database of >2.6 million de-identified electronic health records linked to BioVU, which is a DNA biobank with more than 230,000 unique samples. To ensure these data are used to maximally benefit and accelerate both de novo drug discovery and drug repurposing efforts, we created the Accelerating Drug Development and Repurposing Incubator, a multidisciplinary think tank of experts in various therapeutic areas within both basic and clinical science as well as experts in legal, business, and other operational domains. The Incubator supports a diverse pipeline of drug indication finding projects, leveraging the natural experiment of human genetics.
    MeSH term(s) Databases, Genetic ; Drug Design ; Drug Repositioning/methods ; Genetic Predisposition to Disease/genetics ; Genome, Human/genetics ; Humans ; Pharmacogenomic Testing/methods ; Precision Medicine/methods
    Language English
    Publishing date 2017-04
    Publishing country United States
    Document type Journal Article ; Technical Report
    ISSN 1557-8127
    ISSN (online) 1557-8127
    DOI 10.1089/adt.2016.772
    Database MEDical Literature Analysis and Retrieval System OnLINE

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