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Article: Informing the State of Process Modeling and Automation of Blood Banking and Transfusion Services Through a Systematic Mapping Study.

Elhaj, Shaima' Abdallah / Odeh, Yousra / Tbaishat, Dina / Rjoop, Anwar / Mansour, Asem / Odeh, Mohammed

2024 Volume 17, Page(s) 473–489

Abstract: Purpose: The current state of the art in process modeling of blood banking and transfusion services is not well grounded; methodological reviews are lacking to bridge the gap between such blood banking and transfusion processes (and their models) and ... ...

Abstract	Purpose: The current state of the art in process modeling of blood banking and transfusion services is not well grounded; methodological reviews are lacking to bridge the gap between such blood banking and transfusion processes (and their models) and their automation. This research aims to fill this gap with a methodological review. Methods: A systematic mapping study was adopted, driven by five key research questions. Identified research studies were accepted based on fulfilling the following inclusion criteria: 1) research studies should focus on blood banking and transfusion process modeling since the late 1970s; and 2) research studies should focus on process automation in relation to workflow-based systems, with papers classified into categories in line with the analysis undertaken to answer each of the research questions. Results: The search identified 22 papers related to modeling and automation of blood banking and transfusion, published in the period 1979-2022. The findings revealed that only four process modeling languages were reported to visualize process workflows. The preparation of blood components, serologic testing, blood distribution, apheresis, preparation for emergencies, maintaining blood banking and transfusion safety, and documentation have not been reported to have been modeled in the literature. This review revealed the lack of use of Business Process Modeling Notation (BPMN) as the industry standard process modeling language in the domain. The review also indicated a deficiency in modeling specialized processes in blood banking and transfusion, with the majority of reported processes being described as high level, but lacking elaboration. Automation was reported to improve transfusion safety, and to reduce cost, time cycle, and human errors. Conclusion: The work highlights the non-existence of a developed process architectural framework for blood banking and transfusion processes, which is needed to lay the groundwork for identifying and modeling strategic, managerial, and operational processes to bridge the gap with their enactment in healthcare systems. This paves the way for the development of a data-harvesting platform for blood banking and transfusion services.
Language	English
Publishing date	2024-02-01
Publishing country	New Zealand
Document type	Journal Article ; Review
ZDB-ID	2453343-9
ISSN	1178-2390
ISSN	1178-2390
DOI	10.2147/JMDH.S443674
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Hydroxocobalamin as Rescue Therapy in a Patient With Refractory Amlodipine-Induced Vasoplegia.

Ayasa, Laith A / Azar, Jehad / Odeh, Anas / Ayyad, Mohammed / Shbaita, Sara / Zidan, Thabet / Awwad, Noor Al-Deen / Kawa, Nagham M / Awad, Wafaa

Cureus

2023 Volume 15, Issue 5, Page(s) e38400

Abstract: Vasoplegic syndrome is a type of distributive shock characterized by mean arterial pressure of less than 65 mmHg, with normal to high cardiac output and often refractory to fluid resuscitation, high doses of intravenous vasopressors, and inotropes. It is ...

Abstract	Vasoplegic syndrome is a type of distributive shock characterized by mean arterial pressure of less than 65 mmHg, with normal to high cardiac output and often refractory to fluid resuscitation, high doses of intravenous vasopressors, and inotropes. It is usually observed after cardiac and solid organ transplantation surgeries. Here, we report a 56-year-old female patient who presented with a profound vasoplegia manifesting as lethargy and confusion in the setting of amlodipine toxicity. This case of severe vasoplegia was refractory to all conditional lines of medical management reported in the literature. The mainstay treatment modalities for vasoplegia include volume resuscitation, catecholamines, vasopressin, angiotensin II, and possibly methylene blue in unresponsive cases. Our patient was given hydroxocobalamin in favor of methylene blue, given the history of serotonin reuptake inhibitors use, which would have caused a life-threatening serotonin syndrome. Hydroxycobolamine resulted in a dramatic clinical recovery, suggesting its potentially significant role in refractory vasoplegia.
Language	English
Publishing date	2023-05-01
Publishing country	United States
Document type	Case Reports
ZDB-ID	2747273-5
ISSN	2168-8184
ISSN	2168-8184
DOI	10.7759/cureus.38400
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Article: iOntoBioethics: A Framework for the Agile Development of Bioethics Ontologies in Pandemics, Applied to COVID-19.

Odeh, Mohammed / Kharbat, Faten F / Yousef, Rana / Odeh, Yousra / Tbaishat, Dina / Hakooz, Nancy / Dajani, Rana / Mansour, Asem

Frontiers in medicine

2021 Volume 8, Page(s) 619978

Abstract: Background: ...

Abstract	Background:
Language	English
Publishing date	2021-05-21
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2775999-4
ISSN	2296-858X
ISSN	2296-858X
DOI	10.3389/fmed.2021.619978
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Article: Factors Affecting the Outcomes of First in vitro Fertilization and Embryo Transfer: A Retrospective Investigation.

Muhaidat, Nadia / Karam, Abdulrahman M / Nabhan, Mohammed Saad / Dabbah, Tala / Odeh, Bilal / Eid, Mira / Almahallawi, Nadia Jamal / Alshrouf, Mohammad Ali

International journal of women's health

2023 Volume 15, Page(s) 1537–1545

Abstract: Background: The outcome of embryo transfer (ET) is multifactorial. A variety of patient-related, procedural-related, and operator-related factors are known to play a role. This study aims to evaluate the outcomes of ET and determine the factors that ... ...

Abstract	Background: The outcome of embryo transfer (ET) is multifactorial. A variety of patient-related, procedural-related, and operator-related factors are known to play a role. This study aims to evaluate the outcomes of ET and determine the factors that affect the outcome. Methods: The study involved a retrospective design involving 300 first in vitro fertilization and embryo transfer (IVF-ET) cycles between 2011 and 2021. The outcome included 155 unsuccessful cycles and 145 successful IVF-ET leading to pregnancy. The outcomes were examined for different variables, including age, weight, height, body mass index, cause of infertility, number of embryos fertilized during the cycle, day of ET, whether the embryo was frozen, presence of blood or mucus during the procedure, the use of a stylet, tenaculum, uterine sound/dilator, and catheter type. Logistic regression was used to analyze factors affecting the outcomes of ET. Results: The mean age was 27.84 ± 3.77 years. Patients who had blood during the procedure (32.9% vs 17.2%, p = 0.002), mucus (31% vs 20.7%, p = 0.049), or used the tenaculum (16.8% vs 6.9%, p = 0.012) were more likely to have unsuccessful IVF-ET. Logistic regression to adjust for related factors revealed that the presence of blood (AOR = 2.21, 95% CI 1.04 to 4.66, p = 0.038) during the ET had a higher likelihood of an unsuccessful outcome. Conclusion: This study showed that the presence of blood during the ET cycle influenced clinical pregnancy. This highlights the importance of performing the procedure under atraumatic conditions. Level of evidence: Level III; retrospective comparative study.
Language	English
Publishing date	2023-10-11
Publishing country	New Zealand
Document type	Journal Article
ZDB-ID	2508161-5
ISSN	1179-1411
ISSN	1179-1411
DOI	10.2147/IJWH.S431468
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Article ; Online: Host range, severity and trans boundary transmission of Orf virus (ORFV).

Abu Ghazaleh, Robin / Al-Sawalhe, Mohammed / Abu Odeh, Insaf / El Ibrahim, Jehad / Al-Turman, Basem / Makhamreh, Jamil

Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases

2023 Volume 112, Page(s) 105448

Abstract: Contagious ecthyma in small ruminants is a zoonotic disease caused by Orf virus (ORFV) in the genus Parapoxvirus that can be deadly to its natural hosts. It causes significant losses worldwide, and commonly infects humans. However, the literature about ... ...

Abstract	Contagious ecthyma in small ruminants is a zoonotic disease caused by Orf virus (ORFV) in the genus Parapoxvirus that can be deadly to its natural hosts. It causes significant losses worldwide, and commonly infects humans. However, the literature about its comparative severity in sheep and goat hosts is misleading; and while contagious ecthyma has been shown to occur in camels and transmit to humans, there is confusion as to whether ORFV is responsible. Camels are important from a 'One Health' perspective as they have been implicated as a reservoir host for the virus causing Middle East Respiratory Syndrome (MERS), which has a case fatality rate of 35% in humans. We compared ORFV gene sequences and mortality data from the West Bank in Palestine, where ORFV has not been reported previously, with data from the region. Surprisingly, we found that infections of camels that had been attributed to ORFV were more closely related to a different member of the genus Parapoxvirus. Two Middle East ORFVs isolated from humans were unrelated and sat alongside sheep and goat derived sequences on two distinct ORFV lineages of a maximum likelihood B2L gene tree. One of the viral lineages bifurcated to produce a monophyletic group of goat-derived ORFVs characterized uniquely by a glycine at amino acid reside 249. We found that serine is the ancestral allele shared between ORFV infections of sheep and also two closely related Parapoxviruses (PCPV and CCEV), indicating that the glycine allele represents a more recent shift in virus host range adaptation to goats. Furthermore, and contrary to some reports that ORFV is more severe in goats than in sheep, we observed median mortality of up to 24.5% in sheep, but none in goats. We also identified trans-boundary spread of ORFV between the West Bank and Israel.
MeSH term(s)	Humans ; Sheep ; Animals ; Orf virus/genetics ; Ecthyma, Contagious/epidemiology ; Camelus ; Host Specificity ; Ruminants ; Goats ; Phylogeny
Language	English
Publishing date	2023-05-20
Publishing country	Netherlands
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2037068-4
ISSN	1567-7257 ; 1567-1348
ISSN (online)	1567-7257
ISSN	1567-1348
DOI	10.1016/j.meegid.2023.105448
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Article ; Online: National survey of barriers to colorectal cancer screening in Jordan.

Abdulelah, Zaid Ali / Abdulelah, Ahmed Ali / Alqaisieh, Mohammad / Khanfar, Asim N / Hammad, Nouran Husam / Al Masoud, Eyad Bassam / Odeh, Qusai B / Alshrouf, Mohammad Ali / Abuaisheh, Rahaf Maher / Abd-Alrahman, Haitham Mohammed / Khatib, Amer

Eastern Mediterranean health journal = La revue de sante de la Mediterranee orientale = al-Majallah al-sihhiyah li-sharq al-mutawassit

2024 Volume 30, Issue 2, Page(s) 125–135

Abstract: Background: Colorectal cancer is among the leading malignancies globally and in Jordan. It causes significant morbidity and mortality. It can be detected early, but uptake of colorectal cancer screening in Jordan is substantially low.: Aim: To ... ...

Abstract	Background: Colorectal cancer is among the leading malignancies globally and in Jordan. It causes significant morbidity and mortality. It can be detected early, but uptake of colorectal cancer screening in Jordan is substantially low. Aim: To determine the underlying barriers to the uptake of colorectal cancer screening in Jordan. Methods: A cross-sectional study was conducted in the northern, central and southern regions of Jordan using selfadministered questionnaire that evaluated the barriers and attitudes towards colorectal cancer screening among adults aged 45 years and above living in Jordan. The data was analyzed using SPSS version 25.0. Results: Of the 1477 participants enrolled in the study, 29.1% reported the lack of information about screening as a major barrier to uptake, followed by the fear of any potential complications due to the test (10%), embarrassment associated with colonoscopy (7.8%), and fear of the result (7.4%). Only 9% of the study participants had taken the colonoscopy test for colorectal cancer screening. Conclusion: Lack of information about colorectal cancer screening, misconceptions and embarrassment drive the low uptake of colorectal cancer screening in Jordan. There is a need for nationwide education and awareness on colorectal cancer screening to address the barriers reported in this study and increase screening uptake.
MeSH term(s)	Adult ; Humans ; Jordan ; Cross-Sectional Studies ; Health Knowledge, Attitudes, Practice ; Early Detection of Cancer ; Surveys and Questionnaires ; Colorectal Neoplasms/diagnosis ; Mass Screening
Language	English
Publishing date	2024-02-25
Publishing country	Egypt
Document type	Journal Article
ZDB-ID	1291071-5
ISSN	1687-1634 ; 1020-3397
ISSN (online)	1687-1634
ISSN	1020-3397
DOI	10.26719/emhj.24.028
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Article ; Online: Crystallographic Structure and Quantum-Chemical Analysis of Biologically Active Co(III)-Pyridoxal–Isothiosemicarbazone Complex

Fahad Abdulaziz / Khulood Fahad Alabbosh / Odeh Abdullah Odeh Alshammari / Wasan Mohammed Bin Tuwalah / Tahani Y. A. Alanazi / Aleksandra Rakić / Miljan Barić / Milica Marković / Violeta Jevtovic / Dušan Dimić

Inorganics, Vol 11, Iss 12, p

2023 Volume 466

Abstract: Semicarbazones and their transition metal complexes have been investigated as biologically active compounds. This study explores the synthesis, X-ray crystallographic structure, and characterization of a novel Co(III) complex cation with a pyridoxal- ... ...

Abstract	Semicarbazones and their transition metal complexes have been investigated as biologically active compounds. This study explores the synthesis, X-ray crystallographic structure, and characterization of a novel Co(III) complex cation with a pyridoxal-isothiosemicarbazone (PLITSC) ligand, [Co(PLITSC-2H)(NH 3 ) 3 ] + . The structure of the complex was further elucidated by the elemental analysis and spectroscopic techniques (IR and UV–VIS). Hirshfeld surface analysis was applied for the investigation of intermolecular interactions governing crystal structure. Optimization was performed at the B3LYP/6-31 + G(d,p)(H,C,N,O,S)/LanL2DZ(Co) level of theory without any geometrical constraints. The selected level of theory’s applicability was proven after comparing experimental and theoretical bond lengths and angles. The antibacterial activity of the complex towards E. coli and B. subtilis was determined and qualified as moderate compared to Streptomycin. The formation of free radical species in the presence of the complex was further verified in the fluorescence microscopy measurements. The molecular docking towards neural nitric-oxide synthase in the brain has shown that the complex structure and relative distribution of ligands were responsible for the binding to amino acids in the active pocket.
Keywords	DFT ; Co complex ; antimicrobial activity ; methylene blue ; QTAIM ; Inorganic chemistry ; QD146-197
Subject code	540
Language	English
Publishing date	2023-12-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Institutions, Culture, or Interaction

Muhammad Asif Khan / Hossam Haddad / Mahmoud Odeh / Ahsanuddin Haider / Mohammed Arshad Khan

Sustainability, Vol 14, Iss 15883, p

What Determines the Financial Market Development in Emerging Markets?

2022 Volume 15883

Abstract: In this research, we examine how the quality of institutions promotes financial market development (FMD) in 21 emerging markets (classified by the Financial Times Stock Exchange Group). The moderating role of culture is also empirically tested. For this ... ...

Abstract	In this research, we examine how the quality of institutions promotes financial market development (FMD) in 21 emerging markets (classified by the Financial Times Stock Exchange Group). The moderating role of culture is also empirically tested. For this purpose, a balance panel dataset of 21 emerging markets from 1984 to 2020 is utilized from various secondary data sources. The study applies two-stages least square regression with the instrumental variable, and lag transformation to overcome the endogeneity problem in the nexus of institutions and finance, which is least focused on in prior literature. The empirical findings show that institutional quality and the national culture promote FMD in these economies. The main findings are consistent with law and finance, and financial socialization theories. We argue that academics, policymakers, and researchers should comprehend the critical role of institutional and cultural indicators in forming an effective financial system that may lead to sustainable economic development. This research contributes to the literature on emerging markets in this helpful paradigm. We conclude that quality institutions play a critical role in magnifying the FMD of emerging markets. It is crucial to comprehend the connection between FMD and institutions, as the growth dividend from financial development can be boosted by strengthening institutions and understanding the culture. Our results are robust to alternative measures of institutions and FMD and the correction of potential endogeneity.
Keywords	financial market development ; institutional quality ; settler mortality ; culture ; emerging markets ; Environmental effects of industries and plants ; TD194-195 ; Renewable energy sources ; TJ807-830 ; Environmental sciences ; GE1-350
Subject code	339
Language	English
Publishing date	2022-11-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: The Effectiveness of Prehospital Administration of Tranexamic Acid in Reducing Mortality in Trauma Patients: An Overview.

Javeed, Syed S / Altawili, Mohammed A / Almubarak, Lujain Nadhem A / Alaodah, Shoug A / Alqarni, Mohannad Mastour A / Odeh, Omar I / Asiri, Mohammed Ali B / Alotaibi, Rakan Abdulrahman M / Alshammari, Arwa Ahmed A / Alqutayfi, Zainab Adnan M / Altemani, Omniah Salem D / Al Gharban, Dhafer Ahmed M / Zafar, Zohair A

Cureus

2023 Volume 15, Issue 12, Page(s) e49784

Abstract: Tranexamic acid (TXA) is an antifibrinolytic drug that reduces bleeding by inhibiting plasminogen activation and fibrin clot degradation. Its role in prehospital trauma management remains unclear. This article aims to systematically review the current ... ...

Abstract	Tranexamic acid (TXA) is an antifibrinolytic drug that reduces bleeding by inhibiting plasminogen activation and fibrin clot degradation. Its role in prehospital trauma management remains unclear. This article aims to systematically review the current evidence on the effect of prehospital TXA administration on mortality in adult and pediatric trauma patients. A literature search was conducted of PubMed, Web of Science, Scopus, and Cochrane databases from March 2023 to August 2023 for studies evaluating the impact of prehospital TXA use on trauma mortality. Inclusion criteria were articles published in the English language in the past 20 years focusing on clinical outcomes of prehospital TXA administration. Data on all-cause mortality, thromboembolic events, and time to TXA administration were extracted. In adult trauma, prehospital TXA appears to reduce early all-cause mortality when given within three hours of injury without increasing thromboembolic risks. Some studies found decreased delayed mortality, while others found no difference. In pediatric trauma, preliminary evidence suggests TXA may lower in-hospital mortality in hemodynamically unstable patients, though higher doses may increase seizure risk. Early prehospital administration of TXA within three hours of adult trauma may reduce mortality through improved hemorrhage control. Potential benefits in pediatric trauma warrant further investigation, balancing efficacy against safety risks such as seizures from high doses. Well-designed randomized trials are needed to validate optimal TXA dosing strategies across age groups and injury severity levels.
Language	English
Publishing date	2023-12-01
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	2747273-5
ISSN	2168-8184
ISSN	2168-8184
DOI	10.7759/cureus.49784
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Article ; Online: Host range, severity and trans boundary transmission of Orf virus (ORFV)

Abu Ghazaleh, Robin / Al-Sawalhe, Mohammed / Abu Odeh, Insaf / El Ibrahim, Jehad / Al-Turman, Basem / Makhamreh, Jamil

Infection, Genetics and Evolution. 2023 Aug., v. 112 p.105448-

2023

Abstract	Contagious ecthyma in small ruminants is a zoonotic disease caused by Orf virus (ORFV) in the genus Parapoxvirus that can be deadly to its natural hosts. It causes significant losses worldwide, and commonly infects humans. However, the literature about its comparative severity in sheep and goat hosts is misleading; and while contagious ecthyma has been shown to occur in camels and transmit to humans, there is confusion as to whether ORFV is responsible. Camels are important from a 'One Health' perspective as they have been implicated as a reservoir host for the virus causing Middle East Respiratory Syndrome (MERS), which has a case fatality rate of 35% in humans. We compared ORFV gene sequences and mortality data from the West Bank in Palestine, where ORFV has not been reported previously, with data from the region. Surprisingly, we found that infections of camels that had been attributed to ORFV were more closely related to a different member of the genus Parapoxvirus. Two Middle East ORFVs isolated from humans were unrelated and sat alongside sheep and goat derived sequences on two distinct ORFV lineages of a maximum likelihood B2L gene tree. One of the viral lineages bifurcated to produce a monophyletic group of goat-derived ORFVs characterized uniquely by a glycine at amino acid reside 249. We found that serine is the ancestral allele shared between ORFV infections of sheep and also two closely related Parapoxviruses (PCPV and CCEV), indicating that the glycine allele represents a more recent shift in virus host range adaptation to goats. Furthermore, and contrary to some reports that ORFV is more severe in goats than in sheep, we observed median mortality of up to 24.5% in sheep, but none in goats. We also identified trans-boundary spread of ORFV between the West Bank and Israel.
Keywords	Coronavirus infections ; Orf virus ; alleles ; contagious ecthyma ; goats ; host range ; infection ; monophyly ; mortality ; serine ; sheep ; statistical analysis ; viruses ; zoonoses ; Israel ; Palestine ; West Bank ; Parapoxvirus ; Trans boundary ; Zoonosis
Language	English
Dates of publication	2023-08
Publishing place	Elsevier B.V.
Document type	Article ; Online
Note	Use and reproduction
ZDB-ID	2037068-4
ISSN	1567-1348
ISSN	1567-1348
DOI	10.1016/j.meegid.2023.105448
Database	NAL-Catalogue (AGRICOLA)

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