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Article ; Online: Mortality predictors of patients diagnosed with severe hyponatremia in the emergency department.

Gurbuz, Mesut / Acehan, Selen / Satar, Salim / Gulen, Muge / Sevdımbas, Sarper / Ince, Cagdas / Onan, Engin

2024

Abstract: Purpose: To determine the factors affecting mortality as a result of the analysis of the demographic and clinical characteristics and laboratory parameters of patients whose serum Na value was determined to be 125 mEq/L or below at the time of admission ...

Abstract	Purpose: To determine the factors affecting mortality as a result of the analysis of the demographic and clinical characteristics and laboratory parameters of patients whose serum Na value was determined to be 125 mEq/L or below at the time of admission to the emergency department (ED). Method: Patients over 18 years of age who admitted to the ED of a tertiary hospital between September 2021 and September 2022 and whose serum sodium level was determined to be 125 mEq/L and below were included in the study. Demographic and clinical characteristics, admission complaints, medications used, Charles comorbidity index (CCI), laboratory parameters, and outcomes of the patients included in the study were recorded in the data form. Results: Three hundred ninety-nine patients were included in the study. When the 30-day mortality of the patients is examined, the mortality rate was found to be 21.6%. In the analyses performed for the predictive power of laboratory parameters for mortality, it was determined that the highest predictive power among the predictive values determined by the area under the curve (AUC) was the albumin level (AUC 0.801, 95% CI 0.753-0.849, p < 0.001). In the binary logistic regression analysis, urea and albumin were independent predictors of 30-day mortality. Conclusion: According to study data, albumin and urea levels are independent predictors of 30-day mortality in patients diagnosed with severe hyponatremia in the emergency department.
Language	English
Publishing date	2024-01-31
Publishing country	Ireland
Document type	Journal Article
ZDB-ID	390895-1
ISSN	1863-4362 ; 0021-1265
ISSN (online)	1863-4362
ISSN	0021-1265
DOI	10.1007/s11845-024-03615-7
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Article ; Online: Dexketoprofen <em>versus</em> Tenoxicam in Acute Severe Pain Due to Primary Dysmenorrhea.

Satar, Deniz Aka / Satar, Salim / Gulen, Muge / Acehan, Selen / Okcu, Nefise Tanridan / Sahin, Gonca Koksaldi

Journal of the College of Physicians and Surgeons--Pakistan : JCPSP

2024 Volume 34, Issue 2, Page(s) 160–165

Abstract: Objective: To evaluate the analgaesic efficacy of tenoxicam and dexketoprofen in patients admitted to the Emergency Medicine (EM) Clinic with severe acute pain due to primary dysmenorrhea (PD).: Study design: Randomised-controlled trial. Place and ... ...

Abstract	Objective: To evaluate the analgaesic efficacy of tenoxicam and dexketoprofen in patients admitted to the Emergency Medicine (EM) Clinic with severe acute pain due to primary dysmenorrhea (PD). Study design: Randomised-controlled trial. Place and Duration of the Study: Emergency Medicine Clinic, Health Sciences University, Adana City Training and Research Hospital, Adana, Turkiye, from January to December 2022. Methodology: Patients presenting with PD, were divided into two groups of 60 each, administered 50 mg dexketoprofen and 20 mg tenoxicam intravenously. Visual analogue scale (VAS) scores were recorded at the 15th, 30th, 60th, and 120th minutes. VAS scores and ΔVAS scores were compared with the effectiveness of drugs, the need for rescue drugs and its side-effects. Results: Intravenous (IV) dexketoprofen was administered to 60 of the patients and IV tenoxicam was administered to another 60. At the time of admission, mean VAS scores of the patients were 8.8 ± 0.9 for the dexketoprofen group and 8.6 ± 0.8 for the tenoxicam group. The VAS scores of the dexketoprofen group were found to be statistically significantly lower after 30 minutes with lower need for rescue analgaesics. ΔVAS scores of the dexketoprofen group were statistically significantly higher from the 30th minute. Conclusion: According to the VAS scoring, IV dexketoprofen was a more effective drug than IV tenoxicam in patients who were admitted to the EM clinic with severe pain due to PD. Key words: Dexketoprofen, Primary dysmenorrhea, VAS score.
MeSH term(s)	Female ; Humans ; Acute Pain/drug therapy ; Anti-Inflammatory Agents, Non-Steroidal/therapeutic use ; Double-Blind Method ; Dysmenorrhea/drug therapy ; Ketoprofen/analogs & derivatives ; Pain, Postoperative/drug therapy ; Piroxicam/analogs & derivatives ; Tromethamine
Chemical Substances	Anti-Inflammatory Agents, Non-Steroidal ; dexketoprofen trometamol (N674F7L21E) ; Ketoprofen (90Y4QC304K) ; Piroxicam (13T4O6VMAM) ; tenoxicam (Z1R9N0A399) ; Tromethamine (023C2WHX2V)
Language	English
Publishing date	2024-02-12
Publishing country	Pakistan
Document type	Journal Article ; Randomized Controlled Trial
ZDB-ID	2276646-7
ISSN	1681-7168 ; 1022-386X
ISSN (online)	1681-7168
ISSN	1022-386X
DOI	10.29271/jcpsp.2024.02.160
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Article ; Online: Which one predicts mortality better in acute ischemic stroke: negative vs positive acute-phase reactants.

Koca, Ahmet Naci / Acehan, Selen / Satar, Salim / Gulen, Muge / Sevdimbas, Sarper / Gorur, Mehmet / Ozturk, İlker

Neurological research

2024 , Page(s) 1–9

Abstract: Aim: The aim of the study is to investigate the relationship between negative acute-phase reactants and positive acute-phase reactants with in-hospital mortality in patients diagnosed with acute ischemic stroke (AIS) in the emergency department (ED).: ...

Abstract	Aim: The aim of the study is to investigate the relationship between negative acute-phase reactants and positive acute-phase reactants with in-hospital mortality in patients diagnosed with acute ischemic stroke (AIS) in the emergency department (ED). Methods and materials: Patients aged 18 and older who presented to the ED of a tertiary hospital with AIS were included in the study. Demographic and clinical characteristics, laboratory parameters, acute-phase reactants, National Institutes of Health Stroke Scale (NIHSS), and outcome data of the included patients were recorded on a standard data form. Results: A total of 588 patients were included in the study. When the in-hospital mortality of patients was examined, the mortality rate was 17.7%. In the analysis for predicting mortality, it was determined that albumin had the highest predictive power between the area under the curve (AUC) and the determined predictive values (AUC: 0.759, 95% CI 0.707-0.810, Conclusion: According to the study data, albumin and TF levels, which are negative acute-phase reactants, are independent determinants of in-hospital mortality in patients with acute ischemic stroke in the emergency department.
Language	English
Publishing date	2024-03-31
Publishing country	England
Document type	Journal Article
ZDB-ID	424428-x
ISSN	1743-1328 ; 0161-6412
ISSN (online)	1743-1328
ISSN	0161-6412
DOI	10.1080/01616412.2024.2337513
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Article ; Online: Comparison of syncope risk scores in predicting the prognosis of patients presenting to the emergency department with syncope.

Ince, Cagdas / Gulen, Muge / Acehan, Selen / Sevdimbas, Sarper / Balcik, Muhammet / Yuksek, Ali / Satar, Salim

Irish journal of medical science

2023 Volume 192, Issue 6, Page(s) 2727–2734

Abstract: Background: Various scores have been derived for the assessment of syncope patients in the emergency department (ED).: Aim: We aimed to compare the effectiveness of Canadian Syncope Risk Scores (CSRS), San Francisco Syncope Rules (SFSR), and ... ...

Abstract	Background: Various scores have been derived for the assessment of syncope patients in the emergency department (ED). Aim: We aimed to compare the effectiveness of Canadian Syncope Risk Scores (CSRS), San Francisco Syncope Rules (SFSR), and Osservatorio Epidemiologico sulla Sincope nel Lazio (OESIL) risk scores in predicting the risk of major adverse cardiac events (MACE) and mortality among syncope patients within 30 days of the initial ED visit. Methods: We performed a prospective, observational case series study of adults (≥ 18 years) with unexplained syncope/near-syncope who presented to ED. Demographic characteristics of the patients and clinical and laboratory data were recorded in the standard data collection form of the study. Our primary outcome was a 30-day mortality. Results: A total of 421 patients (mean age 50.9 ± 20.8, 51.5% male) were enrolled. The rate of MACE development in the 30-day follow-up of the patients was 12.8% (n = 54). While 20.2% (n = 85) of the patients were hospitalized, two of the patients died in the emergency room and the 30-day mortality was 5.5% (n = 23). CSRS was found to have the highest predictive power of mortality (AUC: 0.869, 95% CI 0.799-0.939, p < 0.001). If the cut-off value of CSRS was 0.5, the sensitivity was found to be 82.6% and the specificity was 81.9%. Also CSRS (OR: 1.402, 95% CI: 1.053-1.867, p = 0.021) was found to be an independent predictor of the 30-day mortality. Conclusion: The CSRS may be used as a safety risk score for a 30-day risk of MACE and mortality after discharge from the emergency department.
MeSH term(s)	Adult ; Female ; Humans ; Male ; Canada ; Emergency Service, Hospital ; Prognosis ; Prospective Studies ; Risk Assessment ; Risk Factors ; Syncope/diagnosis ; Syncope/etiology
Language	English
Publishing date	2023-05-12
Publishing country	Ireland
Document type	Journal Article ; Observational Study
ZDB-ID	390895-1
ISSN	1863-4362 ; 0021-1265
ISSN (online)	1863-4362
ISSN	0021-1265
DOI	10.1007/s11845-023-03395-6
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Article ; Online: Response to Comment on Treatment of carbon monoxide poisoning: high-flow nasal cannula versus non-rebreather face mask.

Yesiloglu, Onder / Gulen, Muge / Satar, Salim / Acehan, Selen / Akoglu, Haldun

Clinical toxicology (Philadelphia, Pa.)

2021 Volume 59, Issue 8, Page(s) 769

MeSH term(s)	Cannula ; Carbon Monoxide Poisoning/therapy ; Carboxyhemoglobin ; Humans ; Masks ; Respiration, Artificial
Chemical Substances	Carboxyhemoglobin (9061-29-4)
Language	English
Publishing date	2021-02-08
Publishing country	England
Document type	Letter ; Comment
ZDB-ID	204476-6
ISSN	1556-9519 ; 0009-9309 ; 0731-3810 ; 1556-3650
ISSN (online)	1556-9519
ISSN	0009-9309 ; 0731-3810 ; 1556-3650
DOI	10.1080/15563650.2021.1877725
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Article ; Online: Angina and Arrhythmia Symptoms Following Multiple Bee Stings: Kounis Syndrome.

Acehan, Selen / Satar, Salim / Gulen, Muge / Yucel, Ceyhun / Segmen, Mustafa Sencer

Wilderness & environmental medicine

2022 Volume 33, Issue 4, Page(s) 417–421

Abstract: Kounis syndrome (KS) is an acute coronary syndrome including coronary spasm, acute myocardial infarction, and stent thrombosis preceded by an anaphylactic, anaphylactoid, allergic, or hypersensitivity injury. In this case presentation, we discussed Type ... ...

Abstract	Kounis syndrome (KS) is an acute coronary syndrome including coronary spasm, acute myocardial infarction, and stent thrombosis preceded by an anaphylactic, anaphylactoid, allergic, or hypersensitivity injury. In this case presentation, we discussed Type I and Type II KS. Case 1 was a 72-y-old man who presented to the emergency department with allergic symptoms and chest pain that developed after multiple bee stings. Electrocardiography showed ST depression in the lateral leads. Case 2 was a 42-y-old woman who presented to the emergency department with complaints of chest pain, dizziness, and presyncope that developed after multiple bee stings. Mobitz Type II Block with right bundle branch block was observed in 42 beats·min
MeSH term(s)	Animals ; Bees ; Humans ; Kounis Syndrome/etiology ; Kounis Syndrome/complications ; Insect Bites and Stings/complications ; Anaphylaxis/diagnosis ; Anaphylaxis/etiology ; Anaphylaxis/therapy ; Chest Pain/complications ; Arrhythmias, Cardiac/diagnosis ; Arrhythmias, Cardiac/etiology ; Thrombosis/complications
Language	English
Publishing date	2022-09-13
Publishing country	United States
Document type	Case Reports
ZDB-ID	1238909-2
ISSN	1545-1534 ; 1080-6032
ISSN (online)	1545-1534
ISSN	1080-6032
DOI	10.1016/j.wem.2022.06.003
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Zs.A 3025: Show issues

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Article ; Online: Evaluation of corrosive poisoning in adult patients.

Acehan, Selen / Satar, Salim / Gulen, Muge / Avci, Akkan

The American journal of emergency medicine

2020 Volume 39, Page(s) 65–70

Abstract: Objective: To evaluate the demographic characteristics, endoscopy results, emerging complications and the final status of caustic intake cases admitted to our emergency department.: Method: This study is a retrospective one concerning patients ... ...

Abstract	Objective: To evaluate the demographic characteristics, endoscopy results, emerging complications and the final status of caustic intake cases admitted to our emergency department. Method: This study is a retrospective one concerning patients admitted to our emergency department due to caustic ingestion. Demographic characteristics of the patients, complaints while applying to the hospital, physical examination findings, the purpose of caustic intake, the characteristics of corrosive substance taken, times of endoscopy following admission to the emergency department, follow-up times in the emergency department, endoscopic staging and outcome. The data were analyzed through IBM SPSS Statistics Base 22.0 package program. Results: Seventy four patients participated in the study. 83.8% of corrosive substance intake cases were accidental and 16.2% cases were suicidal intention. While 60.8% of the corrosive substances taken had alkaline property, 36.5% were acidic and 2.7% were found to be unknown substances. 50% of the corrosive substance intakes were sodium hypochlorite. It was seen that endoscopy was performed in 59 patients who accepted endoscopy within an average of 244.07 min after admission to the emergency department. While no damage could be seen in 55.9% of patients following endoscopy, the most common injury was Grade 1 (35.6%). Conclusion: Corrosive substance intake is a rare but potentially devastating poisoning with high morbidity and mortality. Mucosal injury begins within minutes following corrosive intake. Therefore, early endoscopy is helpful in assessing the degree of injury and early discharge from hospital.
MeSH term(s)	Accidents/statistics & numerical data ; Adolescent ; Adult ; Burns, Chemical/diagnosis ; Caustics/poisoning ; Endoscopy/methods ; Female ; Humans ; Male ; Middle Aged ; Retrospective Studies ; Sodium Hypochlorite/poisoning ; Young Adult
Chemical Substances	Caustics ; Sodium Hypochlorite (DY38VHM5OD)
Language	English
Publishing date	2020-01-08
Publishing country	United States
Document type	Journal Article
ZDB-ID	605890-5
ISSN	1532-8171 ; 0735-6757
ISSN (online)	1532-8171
ISSN	0735-6757
DOI	10.1016/j.ajem.2020.01.016
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Article: Acute pancreatitis due to hypertriglyceridemia: Plasmapheresis versus medical treatment.

Sahin, Gonca Koksaldi / Gulen, Muge / Acehan, Selen / Unlu, Nurdan / Celik, Yilmaz / Satar, Deniz Aka / Segmen, Mustafa Sencer / Satar, Salim

Turkish journal of emergency medicine

2023 Volume 23, Issue 2, Page(s) 111–118

Abstract: Objective: Hypertriglyceridemia (HTG) is the third-most common cause of acute pancreatitis. Plasmapheresis is an extracorporeal treatment method used for treatment. This study aimed to investigate the efficacy of medical treatment and plasmapheresis in ... ...

Abstract	Objective: Hypertriglyceridemia (HTG) is the third-most common cause of acute pancreatitis. Plasmapheresis is an extracorporeal treatment method used for treatment. This study aimed to investigate the efficacy of medical treatment and plasmapheresis in patients with acute pancreatitis due to HTG. Methods: This was a retrospective cross-sectional study. The patients were divided into two groups according to the treatment they received as those who received only medical treatment and those who performed plasmapheresis with medical treatment. According to the treatment received by the patients; clinical, demographic, and laboratory data, Ranson scores, and bedside index of severity in acute pancreatitis (BISAP) scores, decrease in triglyceride levels in 24 h, length of hospital stay, and outcomes were recorded. Results: Forty-seven patients were included in the study. The level of triglyceride decreases at the 24 Conclusion: Plasma triglyceride levels and BISAP score on admission may help physicians to predict the need for plasmapheresis. Plasmapheresis helps to rapidly reduce triglyceride levels in patients with HTG-associated acute pancreatitis.
Language	English
Publishing date	2023-01-09
Publishing country	India
Document type	Journal Article
ISSN	2452-2473
ISSN	2452-2473
DOI	10.4103/tjem.tjem_276_22
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Article ; Online: Comparison of intravenous ibuprofen and tenoxicam efficiency in ankle injury: a randomized, double-blind study.

Sahin, Gonca Koksaldi / Gulen, Muge / Acehan, Selen / Satar, Deniz Aka / Erfen, Tahsin / Satar, Salim

Irish journal of medical science

2022 Volume 192, Issue 4, Page(s) 1737–1743

Abstract: Background and aim: Pain after soft tissue injuries in and around the ankle is a troublesome process in terms of patient comfort and mobilization. The aim of this study was to compare the analgesic efficacy of intravenous ibuprofen and intravenous ... ...

Abstract	Background and aim: Pain after soft tissue injuries in and around the ankle is a troublesome process in terms of patient comfort and mobilization. The aim of this study was to compare the analgesic efficacy of intravenous ibuprofen and intravenous tenoxicam in patients with acute musculoskeletal pain due to ankle injury. Methods: We conducted a prospective, double-blind, randomized controlled study in a tertiary hospital. The patients were divided into two groups as those administered IV 400 mg ibuprofen and IV 20 mg tenoxicam. After the treatment of the patients, visual analog scale (VAS) scores were recorded at 15, 30, 60, and 120 min. VAS scores were compared with the effectiveness of drugs, their side effects, and the need for rescue drugs. Results: One hundred and twenty-four patients were included in the study. There were 62 patients in the tenoxicam group and 62 patients in the ibuprofen group. When VAS scores were compared, it was found that the VAS scores of the ibuprofen group were statistically significantly lower (p < 0.001). When the ΔVAS scores were compared, it was observed that the ΔVAS scores of the ibuprofen group were statistically significantly higher from 30 min (p < 0.001). There was a statistically significant difference in favor of ibuprofen between the two drug groups in terms of the need for rescue analgesics (p < 0.001). Conclusıon. The analgesic efficacy of intravenous ibuprofen and tenoxicam is equal after an ankle injury. However, after 30 min of drug administration, ibuprofen provides more effective analgesia than tenoxicam.
MeSH term(s)	Humans ; Ibuprofen/therapeutic use ; Double-Blind Method ; Prospective Studies ; Pain, Postoperative/drug therapy ; Treatment Outcome ; Analgesics/therapeutic use ; Ankle Injuries/drug therapy
Chemical Substances	Ibuprofen (WK2XYI10QM) ; tenoxicam (Z1R9N0A399) ; Analgesics
Language	English
Publishing date	2022-09-13
Publishing country	Ireland
Document type	Randomized Controlled Trial ; Journal Article
ZDB-ID	390895-1
ISSN	1863-4362 ; 0021-1265
ISSN (online)	1863-4362
ISSN	0021-1265
DOI	10.1007/s11845-022-03159-8
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Article ; Online: Adding eosinophil count to EMERALD rules predicts subarachnoid haemorrhage better in emergency department.

Kaya, Adem / Satar, Salim / Gulen, Muge / Acehan, Selen / Afser, Kemal Alper / Demirhindi, Hakan

Irish journal of medical science

2022 Volume 192, Issue 3, Page(s) 1453–1462

Abstract: Background: Subarachnoid haemorrhage (SAH) clinical decision rules can provide successful results in the differential diagnosis of non-traumatic headache.: Aim: The aim of this study is to investigate whether a laboratory parameter that can be added ... ...

Abstract	Background: Subarachnoid haemorrhage (SAH) clinical decision rules can provide successful results in the differential diagnosis of non-traumatic headache. Aim: The aim of this study is to investigate whether a laboratory parameter that can be added to clinical decision-making rules can better predict subarachnoid haemorrhages in patients presenting to the emergency department with headache. Methods: We conducted a retrospective cohort study between March 2017 and March 2019. Patients over the age of 18 who admitted to the emergency department with non-traumatic, acute headache last 14 days before admission and evaluated by imaging and laboratory studies were included in the study. Results: A total of 867 patients were included and 141 of them had SAH. In detecting the SAH, Ottawa SAH rule sensitivity (85.1%), specificity (47.1%), positive predictive value (PPV) (23.8%) and negative predictive value (NPV) (94.2%), and for EMERALD SAH, rule sensitivity (96.4%), specificity (43.2%), PPV (24.8%) and NPV (98.4%). In the regression analysis, statistically significant result was obtained to exclude the diagnosis of SAH with the decrease in the eosinophil value (cutoff < 0.085 10^3/µL, OR: 0.011, 95% CI: 0.001-0.213, p = 0.003). When eosinophil value was added to EMERALD SAH rule, it provided a 100% of sensitivity, a 38.4% of specificity, a 24% of PPV and a 100% of NPV in detecting the SAH. Conclusions: EMERALD SAH rule plus eosinophil, which offers 100% sensitivity and NPV for predicting SAH in adult non-traumatic headaches, may be recommended as a successful and practical decision rule for clinical use according to the Ottawa and EMERALD SAH rule.
MeSH term(s)	Adult ; Humans ; Middle Aged ; Retrospective Studies ; Subarachnoid Hemorrhage/diagnostic imaging ; Eosinophils ; Sensitivity and Specificity ; Acute Disease ; Headache/diagnosis ; Headache/etiology ; Emergency Service, Hospital
Language	English
Publishing date	2022-07-25
Publishing country	Ireland
Document type	Journal Article
ZDB-ID	390895-1
ISSN	1863-4362 ; 0021-1265
ISSN (online)	1863-4362
ISSN	0021-1265
DOI	10.1007/s11845-022-03106-7
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