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  1. Article ; Online: Vital role of SHMT2 in diverse disease.

    Ma, Wenqi / Liu, Ronghan / Zhao, Kai / Zhong, Jiangbo

    Biochemical and biophysical research communications

    2023  Volume 671, Page(s) 160–165

    Abstract: One-carbon metabolism is essential for our human cells to carry out nucleotide synthesis, methylation, and reductive metabolism through one-carbon units, and these pathways ensure the high proliferation rate of cancer cells. Serine ... ...

    Abstract One-carbon metabolism is essential for our human cells to carry out nucleotide synthesis, methylation, and reductive metabolism through one-carbon units, and these pathways ensure the high proliferation rate of cancer cells. Serine hydroxymethyltransferase 2 (SHMT2) is a key enzyme in one-carbon metabolism. This enzyme can convert serine into a one-carbon unit bound to tetrahydrofolate and glycine, ultimately supporting the synthesis of thymidine and purines and promoting the growth of cancer cells. Due to SHMT2's crucial role in the one-carbon cycle, it is ubiquitous in human cells and even in all organisms and highly conserved. Here, we summarize the impact of SHMT2 on the progression of various cancers to highlight its potential use in the development of cancer treatments.
    MeSH term(s) Humans ; Protein Processing, Post-Translational ; Cell Proliferation ; Glycine Hydroxymethyltransferase/genetics ; Glycine Hydroxymethyltransferase/metabolism ; Serine/metabolism
    Chemical Substances Glycine Hydroxymethyltransferase (EC 2.1.2.1) ; Serine (452VLY9402)
    Language English
    Publishing date 2023-05-26
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 205723-2
    ISSN 1090-2104 ; 0006-291X ; 0006-291X
    ISSN (online) 1090-2104 ; 0006-291X
    ISSN 0006-291X
    DOI 10.1016/j.bbrc.2023.05.108
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 116: Show issues Location:
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  2. Article ; Online: Initial postoperative plasticity as a predictor of mid-term stereoacuity outcome after surgery for intermittent exotropia.

    Liu, Peipei / Fu, Jing / Zhang, Ronghan / Chu, Hang

    BMC ophthalmology

    2023  Volume 23, Issue 1, Page(s) 213

    Abstract: Background: Intermittent exotropia (IXT) would cause different degrees of damage to stereopsis. We aimed to introduce a visual perception plasticity score (VPPS) that reflects initial postoperative plasticity and evaluate its effectiveness in predicting ...

    Abstract Background: Intermittent exotropia (IXT) would cause different degrees of damage to stereopsis. We aimed to introduce a visual perception plasticity score (VPPS) that reflects initial postoperative plasticity and evaluate its effectiveness in predicting the mid-term surgical outcome in IXT patients.
    Methods: A total of 149 patients with intermittent exotropia who underwent surgery in November 2018 and October 2019 were recruited. All subjects underwent detailed ocular examinations before and after surgery. VPPS were calculated based on visual perception examination system at one week postoperatively. Demographic, angle of deviation and stereopsis were collected and analyzed with regard to the VPPSs preoperatively and at one week, one month, three months, six months postoperatively. Predictive performances of VPPS were assessed using receiver operating characteristic (ROC) curves, the area under the curve (AUC) and cut-offs were obtained.
    Results: Of the 149 patients, the average deviation was 43
    Conclusion: Higher VPPSs were associated with a greater possibility of stereopsis improvement in patients with IXT. VPPS is a potentially promising indicator to predict the mid-term surgical outcome of intermittent exotropia.
    MeSH term(s) Humans ; Area Under Curve ; Depth Perception ; Exotropia/surgery ; Exotropia/diagnosis ; Oculomotor Muscles/surgery ; Ophthalmologic Surgical Procedures ; Postoperative Period ; Retrospective Studies ; Vision, Binocular ; Visual Acuity
    Language English
    Publishing date 2023-05-15
    Publishing country England
    Document type Journal Article
    ZDB-ID 2050436-6
    ISSN 1471-2415 ; 1471-2415
    ISSN (online) 1471-2415
    ISSN 1471-2415
    DOI 10.1186/s12886-023-02958-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Vital role of SHMT2 in diverse disease

    Ma, Wenqi / Liu, Ronghan / Zhao, Kai / Zhong, Jiangbo

    Biochemical and Biophysical Research Communications. 2023 Sept., v. 671 p.160-165

    2023  

    Abstract: One-carbon metabolism is essential for our human cells to carry out nucleotide synthesis, methylation, and reductive metabolism through one-carbon units, and these pathways ensure the high proliferation rate of cancer cells. Serine ... ...

    Abstract One-carbon metabolism is essential for our human cells to carry out nucleotide synthesis, methylation, and reductive metabolism through one-carbon units, and these pathways ensure the high proliferation rate of cancer cells. Serine hydroxymethyltransferase 2 (SHMT2) is a key enzyme in one-carbon metabolism. This enzyme can convert serine into a one-carbon unit bound to tetrahydrofolate and glycine, ultimately supporting the synthesis of thymidine and purines and promoting the growth of cancer cells. Due to SHMT2's crucial role in the one-carbon cycle, it is ubiquitous in human cells and even in all organisms and highly conserved. Here, we summarize the impact of SHMT2 on the progression of various cancers to highlight its potential use in the development of cancer treatments.
    Keywords glycine hydroxymethyltransferase ; humans ; metabolism ; methylation ; purines ; research ; serine ; tetrahydrofolic acid ; thymidine ; One-carbon metabolism ; SHMT2 ; Cancer ; Tumor growth ; Prognostic marker
    Language English
    Dates of publication 2023-09
    Size p. 160-165.
    Publishing place Elsevier Inc.
    Document type Article ; Online
    Note Pre-press version
    ZDB-ID 205723-2
    ISSN 0006-291X ; 0006-291X
    ISSN (online) 0006-291X
    ISSN 0006-291X
    DOI 10.1016/j.bbrc.2023.05.108
    Database NAL-Catalogue (AGRICOLA)

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    In stock of ZB MED Bonn / Germany

    Z 71/706: Show issues
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  4. Article: Construction of a genetic map and QTL mapping of seed size traits in soybean.

    Jiang, Aohua / Liu, Jiaqi / Gao, Weiran / Ma, Ronghan / Tan, Pingting / Liu, Fang / Zhang, Jian

    Frontiers in genetics

    2023  Volume 14, Page(s) 1248315

    Abstract: Soybean seed size and seed shape traits are closely related to plant yield and appearance quality. In this study, 186 individual plants of the ... ...

    Abstract Soybean seed size and seed shape traits are closely related to plant yield and appearance quality. In this study, 186 individual plants of the F
    Language English
    Publishing date 2023-08-25
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2606823-0
    ISSN 1664-8021
    ISSN 1664-8021
    DOI 10.3389/fgene.2023.1248315
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Electrolysis Process-Facilitated Engineering of Primary Particles of Cobalt-Free LiNiO

    Ji, Hongxiang / Qiao, Ronghan / Yu, Hailong / Wang, Shan / Liu, Zhongzhu / Monteiro, Robson / Ribas, Rogerio / Zhu, Yongming / Ben, Liubin / Huang, Xuejie

    ACS applied materials & interfaces

    2023  Volume 15, Issue 33, Page(s) 39291–39303

    Abstract: The particle morphology of ... ...

    Abstract The particle morphology of LiNiO
    Language English
    Publishing date 2023-08-14
    Publishing country United States
    Document type Journal Article
    ISSN 1944-8252
    ISSN (online) 1944-8252
    DOI 10.1021/acsami.3c06908
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Construction of Genetic Map and QTL Mapping for Seed Size and Quality Traits in Soybean (

    Gao, Weiran / Ma, Ronghan / Li, Xi / Liu, Jiaqi / Jiang, Aohua / Tan, Pingting / Xiong, Guoxi / Du, Chengzhang / Zhang, Jijun / Zhang, Xiaochun / Fang, Xiaomei / Yi, Zelin / Zhang, Jian

    International journal of molecular sciences

    2024  Volume 25, Issue 5

    Abstract: Soybean ( ...

    Abstract Soybean (
    MeSH term(s) Humans ; Quantitative Trait Loci ; Glycine max ; Chromosome Mapping/methods ; Plant Breeding ; Phenotype ; Seeds/genetics
    Language English
    Publishing date 2024-03-01
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms25052857
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Transcriptomic and Metabolomic Analyses Reveal the Key Genes Related to Shade Tolerance in Soybean.

    Jiang, Aohua / Liu, Jiaqi / Gao, Weiran / Ma, Ronghan / Zhang, Jijun / Zhang, Xiaochun / Du, Chengzhang / Yi, Zelin / Fang, Xiaomei / Zhang, Jian

    International journal of molecular sciences

    2023  Volume 24, Issue 18

    Abstract: Soybean ( ...

    Abstract Soybean (
    MeSH term(s) Transcriptome ; Glycine max/genetics ; Gene Expression Profiling ; Metabolomics ; Adenosine Triphosphate
    Chemical Substances Adenosine Triphosphate (8L70Q75FXE)
    Language English
    Publishing date 2023-09-18
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms241814230
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  8. Article ; Online: A Comprehensive Study of 3-D Vision-Based Robot Manipulation.

    Cong, Yang / Chen, Ronghan / Ma, Bingtao / Liu, Hongsen / Hou, Dongdong / Yang, Chenguang

    IEEE transactions on cybernetics

    2023  Volume 53, Issue 3, Page(s) 1682–1698

    Abstract: Robot manipulation, for example, pick-and-place manipulation, is broadly used for intelligent manufacturing with industrial robots, ocean engineering with underwater robots, service robots, or even healthcare with medical robots. Most traditional robot ... ...

    Abstract Robot manipulation, for example, pick-and-place manipulation, is broadly used for intelligent manufacturing with industrial robots, ocean engineering with underwater robots, service robots, or even healthcare with medical robots. Most traditional robot manipulations adopt 2-D vision systems with plane hypotheses and can only generate 3-DOF (degrees of freedom) pose accordingly. To mimic human intelligence and endow the robot with more flexible working capabilities, 3-D vision-based robot manipulation has been studied. However, this task is still challenging in the open world especially for general object recognition and pose estimation with occlusion in cluttered backgrounds and human-like flexible manipulation. In this article, we propose a comprehensive analysis of recent progress about the 3-D vision for robot manipulation, including 3-D data acquisition and representation, robot-vision calibration, 3-D object detection/recognition, 6-DOF pose estimation, grasping estimation, and motion planning. We then present some public datasets, evaluation criteria, comparisons, and challenges. Finally, the related application domains of robot manipulation are given, and some future directions and open problems are studied as well.
    Language English
    Publishing date 2023-02-15
    Publishing country United States
    Document type Journal Article
    ISSN 2168-2275
    ISSN (online) 2168-2275
    DOI 10.1109/TCYB.2021.3108165
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Phase Transformation and Performance of Mg-Based Hydrogen Storage Material by Adding ZnO Nanoparticles.

    Zhang, Bing / Liu, Ronghan / Kimura, Hideo / Dou, Yuming / Dai, Ziyin / Xiao, Lirong / Ni, Cui / Hou, Chuanxin / Sun, Xueqin / Yu, Ronghai / Du, Wei / Xie, Xiubo

    Nanomaterials (Basel, Switzerland)

    2023  Volume 13, Issue 8

    Abstract: ZnO nanoparticles in a spherical-like structure were synthesized via filtration and calcination methods, and different amounts of ZnO nanoparticles were added to ... ...

    Abstract ZnO nanoparticles in a spherical-like structure were synthesized via filtration and calcination methods, and different amounts of ZnO nanoparticles were added to MgH
    Language English
    Publishing date 2023-04-09
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662255-5
    ISSN 2079-4991
    ISSN 2079-4991
    DOI 10.3390/nano13081321
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  10. Article ; Online: Glycogen synthase kinase 3 controls T-cell exhaustion by regulating NFAT activation.

    Fu, Yubing / Wang, Jinjia / Liu, Chenfeng / Liao, Kunyu / Gao, Xianjun / Tang, Ronghan / Fan, Binbin / Hong, Yazhen / Xiao, Nengming / Xiao, Changchun / Liu, Wen-Hsien

    Cellular & molecular immunology

    2023  Volume 20, Issue 10, Page(s) 1127–1139

    Abstract: Cellular immunity mediated by ... ...

    Abstract Cellular immunity mediated by CD8
    MeSH term(s) Mice ; Animals ; CD8-Positive T-Lymphocytes ; Glycogen Synthase Kinase 3/metabolism ; T-Cell Exhaustion ; Cell Differentiation ; Neoplasms ; Virus Diseases/metabolism
    Chemical Substances Glycogen Synthase Kinase 3 (EC 2.7.11.26)
    Language English
    Publishing date 2023-08-09
    Publishing country China
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2435097-7
    ISSN 2042-0226 ; 1672-7681
    ISSN (online) 2042-0226
    ISSN 1672-7681
    DOI 10.1038/s41423-023-01075-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6681: Show issues Location:
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