LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 29843

Search options

  1. Book ; Online: TAO Conceptual Design Report

    JUNO Collaboration / Abusleme, Angel / Adam, Thomas / Ahmad, Shakeel / Aiello, Sebastiano / Akram, Muhammad / Ali, Nawab / An, Fengpeng / An, Guangpeng / An, Qi / Andronico, Giuseppe / Anfimov, Nikolay / Antonelli, Vito / Antoshkina, Tatiana / Asavapibhop, Burin / de André, João Pedro Athayde Marcondes / Auguste, Didier / Babic, Andrej / Baldini, Wander /
    Barresi, Andrea / Baussan, Eric / Bellato, Marco / Bergnoli, Antonio / Bernieri, Enrico / Biare, David / Birkenfeld, Thilo / Blin, Sylvie / Blum, David / Blyth, Simon / Bolshakova, Anastasia / Bongrand, Mathieu / Bordereau, Clément / Breton, Dominique / Brigatti, Augusto / Brugnera, Riccardo / Budano, Antonio / Buscemi, Mario / Busto, Jose / Butorov, Ilya / Cabrera, Anatael / Cai, Hao / Cai, Xiao / Cai, Yanke / Cai, Zhiyan / Cammi, Antonio / Campeny, Agustin / Cao, Chuanya / Cao, Guofu / Cao, Jun / Caruso, Rossella / Cerna, Cédric / Chakaberia, Irakli / Chang, Jinfan / Chang, Yun / Chen, Pingping / Chen, Po-An / Chen, Shaomin / Chen, Shenjian / Chen, Xurong / Chen, Yi-Wen / Chen, Yixue / Chen, Yu / Chen, Zhang / Cheng, Jie / Cheng, Yaping / Chepurnov, Alexander / Chiesa, Davide / Chimenti, Pietro / Chukanov, Artem / Chuvashova, Anna / Claverie, Gérard / Clementi, Catia / Clerbaux, Barbara / Di Lorenzo, Selma Conforti / Corti, Daniele / Costa, Salvatore / Corso, Flavio Dal / De La Taille, Christophe / Deng, Jiawei / Deng, Zhi / Deng, Ziyan / Depnering, Wilfried / Diaz, Marco / Ding, Xuefeng / Ding, Yayun / Dirgantara, Bayu / Dmitrievsky, Sergey / Dohnal, Tadeas / Donchenko, Georgy / Dong, Jianmeng / Dornic, Damien / Doroshkevich, Evgeny / Dracos, Marcos / Druillole, Frédéric / Du, Shuxian / Dusini, Stefano / Dvorak, Martin / Enqvist, Timo / Enzmann, Heike / Fabbri, Andrea / Fajt, Lukas / Fan, Donghua / Fan, Lei / Fang, Can / Fang, Jian / Fatkina, Anna / Fedoseev, Dmitry / Fekete, Vladko / Feng, Li-Cheng / Feng, Qichun / Ford, Richard / Formozov, Andrey / Fournier, Amélie / Gan, Haonan / Gao, Feng / Garfagnini, Alberto / Göttel, Alexandre / Genster, Christoph / Giammarchi, Marco / Giaz, Agnese / Giudice, Nunzio / Giuliani, Franco / Gonchar, Maxim / Gong, Guanghua / Gong, Hui / Gorchakov, Oleg / Gornushkin, Yuri / Grassi, Marco / Grewing, Christian / Gromov, Maxim / Gromov, Vasily / Gu, Minghao / Gu, Xiaofei / Gu, Yu / Guan, Mengyun / Guardone, Nunzio / Gul, Maria / Guo, Cong / Guo, Jingyuan / Guo, Wanlei / Guo, Xinheng / Guo, Yuhang / Haacke, Michael / Hackspacher, Paul / Hagner, Caren / Han, Ran / Han, Yang / He, Miao / He, Wei / Heinz, Tobias / Hellmuth, Patrick / Heng, Yuekun / Herrera, Rafael / Hong, Daojin / Hou, Shaojing / Hsiung, Yee / Hu, Bei-Zhen / Hu, Hang / Hu, Jianrun / Hu, Jun / Hu, Shouyang / Hu, Tao / Hu, Zhuojun / Huang, Chunhao / Huang, Guihong / Huang, Hanxiong / Huang, Qinhua / Huang, Wenhao / Huang, Xingtao / Huang, Yongbo / Hui, Jiaqi / Huo, Lei / Huo, Wenju / Huss, Cédric / Hussain, Safeer / Insolia, Antonio / Ioannisian, Ara / Isocrate, Roberto / Jen, Kuo-Lun / Ji, Xiaolu / Ji, Xingzhao / Jia, Huihui / Jia, Junji / Jian, Siyu / Jiang, Di / Jiang, Xiaoshan / Jin, Ruyi / Jing, Xiaoping / Jollet, Cécile / Joutsenvaara, Jari / Jungthawan, Sirichok / Kalousis, Leonidas / Kampmann, Philipp / Kang, Li / Karagounis, Michael / Kazarian, Narine / Khan, Amir / Khan, Waseem / Khosonthongkee, Khanchai / Kinz, Patrick / Korablev, Denis / Kouzakov, Konstantin / Krasnoperov, Alexey / Krokhaleva, Svetlana / Krumshteyn, Zinovy / Kruth, Andre / Kutovskiy, Nikolay / Kuusiniemi, Pasi / Lachenmaier, Tobias / Landini, Cecilia / Leblanc, Sébastien / Lefevre, Frederic / Lei, Liping / Lei, Ruiting / Leitner, Rupert / Leung, Jason / Li, Chao / Li, Demin / Li, Fei / Li, Fule / Li, Haitao / Li, Huiling / Li, Jiaqi / Li, Jin / Li, Kaijie / Li, Mengzhao / Li, Nan / Li, Qingjiang / Li, Ruhui / Li, Shanfeng / Li, Shuaijie / Li, Tao / Li, Teng / Li, Weidong / Li, Weiguo / Li, Xiaomei / Li, Xiaonan / Li, Xinglong / Li, Yi / Li, Yufeng / Li, Zhibing / Li, Ziyuan / Liang, Hao / Liang, Jingjing / Liebau, Daniel / Limphirat, Ayut / Limpijumnong, Sukit / Lin, Guey-Lin / Lin, Shengxin / Lin, Tao / Ling, Jiajie / Lippi, Ivano / Liu, Fang / Liu, Haidong / Liu, Hongbang / Liu, Hongjuan / Liu, Hongtao / Liu, Hu / Liu, Hui / Liu, Jianglai / Liu, Jinchang / Liu, Min / Liu, Qian / Liu, Qin / Liu, Runxuan / Liu, Shuangyu / Liu, Shubin / Liu, Shulin / Liu, Xiaowei / Liu, Yan / Lokhov, Alexey / Lombardi, Paolo / Lombardo, Claudio / Loo, Kai / Lu, Chuan / Lu, Haoqi / Lu, Jingbin / Lu, Junguang / Lu, Shuxiang / Lu, Xiaoxu / Lubsandorzhiev, Bayarto / Lubsandorzhiev, Sultim / Ludhova, Livia / Luo, Fengjiao / Luo, Guang / Luo, Pengwei / Luo, Shu / Luo, Wuming / Lyashuk, Vladimir / Ma, Qiumei / Ma, Si / Ma, Xiaoyan / Ma, Xubo / Maalmi, Jihane / Malyshkin, Yury / Mantovani, Fabio / Manzali, Francesco / Mao, Xin / Mao, Yajun / Mari, Stefano M. / Marini, Filippo / Marium, Sadia / Martellini, Cristina / Martin-Chassard, Gisele / Martini, Agnese / Mayilyan, Davit / Müller, Axel / Meng, Yue / Meregaglia, Anselmo / Meroni, Emanuela / Meyhöfer, David / Mezzetto, Mauro / Miller, Jonathan / Miramonti, Lino / Monforte, Salvatore / Montini, Paolo / Montuschi, Michele / Morozov, Nikolay / Muralidharan, Pavithra / Nastasi, Massimiliano / Naumov, Dmitry V. / Naumova, Elena / Nemchenok, Igor / Nikolaev, Alexey / Ning, Feipeng / Ning, Zhe / Nunokawa, Hiroshi / Oberauer, Lothar / Ochoa-Ricoux, Juan Pedro / Olshevskiy, Alexander / Orestano, Domizia / Ortica, Fausto / Pan, Hsiao-Ru / Paoloni, Alessandro / Parkalian, Nina / Parmeggiano, Sergio / Payupol, Teerapat / Pei, Yatian / Pelliccia, Nicomede / Peng, Anguo / Peng, Haiping / Perrot, Frédéric / Petitjean, Pierre-Alexandre / Petrucci, Fabrizio / Rico, Luis Felipe Piñeres / Popov, Artyom / Poussot, Pascal / Pratumwan, Wathan / Previtali, Ezio / Qi, Fazhi / Qi, Ming / Qian, Sen / Qian, Xiaohui / Qiao, Hao / Qin, Zhonghua / Qiu, Shoukang / Rajput, Muhammad / Ranucci, Gioacchino / Raper, Neill / Re, Alessandra / Rebber, Henning / Rebii, Abdel / Ren, Bin / Ren, Jie / Rezinko, Taras / Ricci, Barbara / Robens, Markus / Roche, Mathieu / Rodphai, Narongkiat / Romani, Aldo / Roskovec, Bedřich / Roth, Christian / Ruan, Xiangdong / Ruan, Xichao / Rujirawat, Saroj / Rybnikov, Arseniy / Sadovsky, Andrey / Saggese, Paolo / Salamanna, Giuseppe / Sanfilippo, Simone / Sangka, Anut / Sanguansak, Nuanwan / Sawangwit, Utane / Sawatzki, Julia / Sawy, Fatma / Schever, Michaela / Schuler, Jacky / Schwab, Cédric / Schweizer, Konstantin / Selivanov, Dmitry / Selyunin, Alexandr / Serafini, Andrea / Settanta, Giulio / Settimo, Mariangela / Shahzad, Muhammad / Shi, Gang / Shi, Jingyan / Shi, Yongjiu / Shutov, Vitaly / Sidorenkov, Andrey / Simkovic, Fedor / Sirignano, Chiara / Siripak, Jaruchit / Sisti, Monica / Slupecki, Maciej / Smirnov, Mikhail / Smirnov, Oleg / Sogo-Bezerra, Thiago / Songwadhana, Julanan / Soonthornthum, Boonrucksar / Sotnikov, Albert / Sramek, Ondrej / Sreethawong, Warintorn / Stahl, Achim / Stanco, Luca / Stankevich, Konstantin / Stefanik, Dus / Steiger, Hans / Steinmann, Jochen / Sterr, Tobias / Stock, Matthias Raphael / Strati, Virginia / Studenikin, Alexander / Sun, Gongxing / Sun, Shifeng / Sun, Xilei / Sun, Yongjie / Sun, Yongzhao / Suwonjandee, Narumon / Szelezniak, Michal / Tang, Jian / Tang, Qiang / Tang, Quan / Tang, Xiao / Tietzsch, Alexander / Tkachev, Igor / Tmej, Tomas / Treskov, Konstantin / Triossi, Andrea / Troni, Giancarlo / Trzaska, Wladyslaw / Tuve, Cristina / van Waasen, Stefan / Boom, Johannes Vanden / Vanroyen, Guillaume / Vassilopoulos, Nikolaos / Vedin, Vadim / Verde, Giuseppe / Vialkov, Maxim / Viaud, Benoit / Volpe, Cristina / Vorobel, Vit / Votano, Lucia / Walker, Pablo / Wang, Caishen / Wang, Chung-Hsiang / Wang, En / Wang, Guoli / Wang, Jian / Wang, Jun / Wang, Kunyu / Wang, Lu / Wang, Meifen / Wang, Meng / Wang, Ruiguang / Wang, Siguang / Wang, Wei / Wang, Wenshuai / Wang, Xi / Wang, Xiangyue / Wang, Yangfu / Wang, Yaoguang / Wang, Yi / Wang, Yifang / Wang, Yuanqing / Wang, Yuman / Wang, Zhe / Wang, Zheng / Wang, Zhimin / Wang, Zongyi / Watcharangkool, Apimook / Wei, Lianghong / Wei, Wei / Wei, Yadong / Wen, Liangjian / Wiebusch, Christopher / Wong, Steven Chan-Fai / Wonsak, Bjoern / Wu, Diru / Wu, Fangliang / Wu, Qun / Wu, Wenjie / Wu, Zhi / Wurm, Michael / Wurtz, Jacques / Wysotzki, Christian / Xi, Yufei / Xia, Dongmei / Xie, Yuguang / Xie, Zhangquan / Xing, Zhizhong / Xu, Benda / Xu, Donglian / Xu, Fanrong / Xu, Jilei / Xu, Jing / Xu, Meihang / Xu, Yin / Xu, Yu / Yan, Baojun / Yan, Xiongbo / Yan, Yupeng / Yang, Anbo / Yang, Changgen / Yang, Huan / Yang, Jie / Yang, Lei / Yang, Xiaoyu / Yang, Yifan / Yao, Haifeng / Yasin, Zafar / Ye, Jiaxuan / Ye, Mei / Yegin, Ugur / Yermia, Frédéric / Yi, Peihuai / Yin, Xiangwei / You, Zhengyun / Yu, Boxiang / Yu, Chiye / Yu, Chunxu / Yu, Hongzhao / Yu, Miao / Yu, Xianghui / Yu, Zeyuan / Yuan, Chengzhuo / Yuan, Ying / Yuan, Zhenxiong / Yuan, Ziyi / Yue, Baobiao / Zafar, Noman / Zambanini, Andre / Zeng, Pan / Zeng, Shan / Zeng, Tingxuan / Zeng, Yuda / Zhan, Liang / Zhang, Feiyang / Zhang, Guoqing / Zhang, Haiqiong / Zhang, Honghao / Zhang, Jiawen / Zhang, Jie / Zhang, Jingbo / Zhang, Peng / Zhang, Qingmin / Zhang, Shiqi / Zhang, Tao / Zhang, Xiaomei / Zhang, Xuantong / Zhang, Yan / Zhang, Yinhong / Zhang, Yiyu / Zhang, Yongpeng / Zhang, Yuanyuan / Zhang, Yumei / Zhang, Zhenyu / Zhang, Zhijian / Zhao, Fengyi / Zhao, Jie / Zhao, Rong / Zhao, Shujun / Zhao, Tianchi / Zheng, Dongqin / Zheng, Hua / Zheng, Minshan / Zheng, Yangheng / Zhong, Weirong / Zhou, Jing / Zhou, Li / Zhou, Nan / Zhou, Shun / Zhou, Xiang / Zhu, Jiang / Zhu, Kejun / Zhuang, Honglin / Zong, Liang / Zou, Jiaheng

    A Precision Measurement of the Reactor Antineutrino Spectrum with Sub-percent Energy Resolution

    2020  

    Abstract: The Taishan Antineutrino Observatory (TAO, also known as JUNO-TAO) is a satellite experiment ...

    Abstract The Taishan Antineutrino Observatory (TAO, also known as JUNO-TAO) is a satellite experiment of the Jiangmen Underground Neutrino Observatory (JUNO). A ton-level liquid scintillator detector will be placed at about 30 m from a core of the Taishan Nuclear Power Plant. The reactor antineutrino spectrum will be measured with sub-percent energy resolution, to provide a reference spectrum for future reactor neutrino experiments, and to provide a benchmark measurement to test nuclear databases. A spherical acrylic vessel containing 2.8 ton gadolinium-doped liquid scintillator will be viewed by 10 m^2 Silicon Photomultipliers (SiPMs) of >50% photon detection efficiency with almost full coverage. The photoelectron yield is about 4500 per MeV, an order higher than any existing large-scale liquid scintillator detectors. The detector operates at -50 degree C to lower the dark noise of SiPMs to an acceptable level. The detector will measure about 2000 reactor antineutrinos per day, and is designed to be well shielded from cosmogenic backgrounds and ambient radioactivities to have about 10% background-to-signal ratio. The experiment is expected to start operation in 2022.

    Comment: 134 pages, 114 figures
    Keywords Physics - Instrumentation and Detectors ; High Energy Physics - Experiment ; Nuclear Experiment
    Subject code 660
    Publishing date 2020-05-18
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    More links

    Kategorien

  2. Article: Endovascular Excimer Laser-Assisted Balloon Angioplasty for Infrapopliteal Arteries in Thromboangiitis Obliterans: A Treatment for Acute-Phase TAO.

    Pu, Hongji / Jiang, Yihong / Wu, Zhaoyu / Lei, Jiahao / Hu, Jiateng / Qiu, Peng / Zhang, Xing / Huang, Qun / Lu, Xinwu / Yin, Minyi / Zhao, Zhen

    Frontiers in cardiovascular medicine

    2022  Volume 9, Page(s) 831340

    Abstract: Background: Thromboangiitis obliterans (TAO, Buerger's disease) is an inflammatory and obstructive ... with acute infrapopliteal TAO.: Method: This was a single-center retrospective cohort study. In this study ... is a feasible, effective, and safe method to treat acute infrapopliteal TAO. ...

    Abstract Background: Thromboangiitis obliterans (TAO, Buerger's disease) is an inflammatory and obstructive vasculopathy, which leads to limb ischemic rest pain and ulcerations in the acute stage.
    Objectives: This study aimed to assess the feasibility of excimer laser-assisted balloon angioplasty (BA) for patients with acute infrapopliteal TAO.
    Method: This was a single-center retrospective cohort study. In this study, 220 patients with 210 target limbs between January 2012 and September 2021 were involved. Among them, 52 target limbs have received endovascular excimer laser-assisted balloon angioplasty from January 2017. The ankle brachial index (ABI), rest pain score, ulcer, Rutherford classification, and TASC II classification were assessed. The follow-up time was 6 months.
    Results: The technical success rate of laser + BA and BA groups was 71.15 and 65.82% (
    Conclusion: Excimer laser debulking-assisted angioplasty is a feasible, effective, and safe method to treat acute infrapopliteal TAO.
    Language English
    Publishing date 2022-03-04
    Publishing country Switzerland
    Document type Case Reports
    ZDB-ID 2781496-8
    ISSN 2297-055X
    ISSN 2297-055X
    DOI 10.3389/fcvm.2022.831340
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  3. Article: The photoelectron-imaging spectroscopic study and chemical bonding analysis of VO₂⁻, NbO₂⁻ and TaO₂⁻

    Zhang, Jiangle / Chen, Shanjun / Jiang, Yihuang / Wang, Chen / Qin, Zhengbo / Qiu, Xingtai / Yu, Jingxiong / Chen, Yuwan / Tang, Zichao

    RSC advances. 2020 Nov. 13, v. 10, no. 68

    2020  

    Abstract: The transition-metal di-oxides, namely VO₂⁻, NbO₂⁻ and TaO₂⁻ have been studied using photoelectron ... affinities of VO₂⁻, NbO₂⁻ and TaO₂⁻ are confirmed to be 2.029(8), 1.901(10) and 2.415(8) eV, respectively ... distribution (PAD) for VO₂⁻, NbO₂⁻ and TaO₂⁻ is correlated to the photo-detachment of the highest occupied ...

    Abstract The transition-metal di-oxides, namely VO₂⁻, NbO₂⁻ and TaO₂⁻ have been studied using photoelectron velocity map imaging (PE-VMI) in combination with theoretical calculations. The adiabatic electron affinities of VO₂⁻, NbO₂⁻ and TaO₂⁻ are confirmed to be 2.029(8), 1.901(10) and 2.415(8) eV, respectively. By combining Franck–Condon (FC) simulation with theoretical calculations, the vibrational feature related to Nb–O and Ta–O stretching modes for the ground state has been unveiled. The photoelectron angular distribution (PAD) for VO₂⁻, NbO₂⁻ and TaO₂⁻ is correlated to the photo-detachment of the highest occupied molecular orbitals (HOMOs), which primarily gets involved in s- and d-orbitals of the V, Nb and Ta atoms. A variety of theoretical calculations have been used to analyze the chemical bonding features of VO₂⁻¹/⁰, NbO₂⁻¹/⁰ and TaO₂⁻¹/⁰, which show that the strong M–O (M = V, Nb and Ta) bond is mainly characterized as ionicity.
    Keywords chemical bonding ; image analysis ; spectral analysis ; velocity
    Language English
    Dates of publication 2020-1113
    Size p. 41612-41617.
    Publishing place The Royal Society of Chemistry
    Document type Article
    Note NAL-light
    ISSN 2046-2069
    DOI 10.1039/d0ra07583c
    Database NAL-Catalogue (AGRICOLA)

    More links

    Kategorien

  4. Article ; Online: Microstructure and nonohmic properties of SnO₂-Ta₂O₅-ZnO system doped with ZrO₂.

    Fu, Xiuli / Jiang, Feng / Gao, Ruichao / Peng, Zhijian

    TheScientificWorldJournal

    2014  Volume 2014, Page(s) 754890

    Abstract: The microstructure and nonohmic properties of SnO₂-Ta₂O₅-ZnO varistor system doped with different ...

    Abstract The microstructure and nonohmic properties of SnO₂-Ta₂O₅-ZnO varistor system doped with different amounts of ZrO₂ (0-2.0 mol%) were investigated. The proposed samples were sintered at 1400°C for 2 h with conventional ceramic processing method. By X-ray diffraction, SnO₂ cassiterite phase was found in all the samples, and no extra phases were identified in the detection limit. The doping of ZrO₂ would degrade the densification of the varistor ceramics but inhibit the growth of SnO₂ grains. In the designed range, varistors with 1.0 mol% ZrO₂ presented the maximum nonlinear exponent of 15.9 and lowest leakage current of 110  μA/cm², but the varistor voltage increased monotonously with the doping amount of ZrO₂.
    MeSH term(s) Hot Temperature ; Microscopy, Electron, Scanning ; Molecular Conformation ; Tantalum/chemistry ; Tin Compounds/chemistry ; X-Ray Diffraction ; Zinc Oxide/chemistry ; Zirconium/chemistry
    Chemical Substances Tin Compounds ; Tantalum (6424HBN274) ; Zirconium (C6V6S92N3C) ; stannic oxide (KM7N50LOS6) ; zirconium oxide (S38N85C5G0) ; Zinc Oxide (SOI2LOH54Z)
    Language English
    Publishing date 2014-01-20
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2075968-X
    ISSN 1537-744X ; 1537-744X
    ISSN (online) 1537-744X
    ISSN 1537-744X
    DOI 10.1155/2014/754890
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  5. Article ; Online: The effects of Tao-Hong-Si-Wu on hepatic necroinflammatory activity and fibrosis in a murine model of chronic liver disease.

    Xi, Shengyan / Shi, Mengmeng / Jiang, Xueqiang / Minuk, Gerald Y / Cheng, Yao / Peng, Ying / Gong, Yuewen / Xu, Yangxinzi / Wang, Xinrong / Yang, Jiaqi / Yue, Lifeng / Wang, Yanhui

    Journal of ethnopharmacology

    2016  Volume 180, Page(s) 28–36

    Abstract: Background: Tao-Hong-Si-Wu decoction (THSWD) is a traditional Chinese herbal medicine that has ...

    Abstract Background: Tao-Hong-Si-Wu decoction (THSWD) is a traditional Chinese herbal medicine that has been used for centuries in the treatment of Chinese patients with chronic liver disease. Recently, THSWD has been reported to alter vascular endothelial growth factor (VEGF) induced angiogenesis, raising the possibility that in addition to its anti-inflammatory properties; THSWD might also inhibit hepatic blood flow associated fibrosis.
    Aim: To document the effects of THSWD on hepatic necroinflammatory disease activity, fibrosis and VEGF signaling in a murine model of chronic liver disease.
    Methods: Sixty adult mice were equally divided into six study groups. Five groups were exposed to subcutaneous carbon tetrachloride (0.1 ml/10 g BW) for six weeks. Three of the five groups were treated with different concentrations of THSWD (4.25, 8.50, 17.00 g/kg), one with 0.1mg/kg of Colchicine (positive control), and one with physiologic saline (negative control). Mice in the sixth group were not exposed to CCl4 and remained untreated (healthy controls). Liver enzymes/function tests, hyaluronic acid and laminin levels were measured in serum, and hepatic histology, VEGF, Flt-1 and kinase insert domain-containing receptor (KDR), Akt and phosphorylated Akt (pAkt) expression were documented in liver tissue at the end of treatment.
    Results: Hepatic necroinflammatory disease activity and fibrosis were significantly attenuated in THSWD treated mice in a dose dependent manner. These beneficial results were similar and often exceeded those achieved with Colchicine. In addition, VEGF, Flt-1, KDR, Akt and pAkt mRNA and protein expression were reduced in TSHWD treated mice.
    Conclusions: In this animal model of chronic liver disease, THSWD decreased hepatic necroinflammatory disease and fibrosis. Inhibition of VEGF expression and downstream signaling were associated with these findings. Further studies with this and other TCMs as treatment for chronic liver disease are warranted.
    MeSH term(s) Animals ; Anti-Inflammatory Agents/pharmacology ; Anti-Inflammatory Agents/therapeutic use ; Carbon Tetrachloride ; Chemical and Drug Induced Liver Injury/drug therapy ; Chemical and Drug Induced Liver Injury/metabolism ; Chemical and Drug Induced Liver Injury/pathology ; Disease Models, Animal ; Drugs, Chinese Herbal/pharmacology ; Drugs, Chinese Herbal/therapeutic use ; Female ; Liver/drug effects ; Liver/metabolism ; Liver/pathology ; Liver Cirrhosis/chemically induced ; Liver Cirrhosis/drug therapy ; Liver Cirrhosis/metabolism ; Liver Cirrhosis/pathology ; Male ; Medicine, Chinese Traditional ; Mice ; Phytotherapy ; Proto-Oncogene Proteins c-akt/genetics ; Proto-Oncogene Proteins c-akt/metabolism ; RNA, Messenger/metabolism ; Vascular Endothelial Growth Factor A/genetics ; Vascular Endothelial Growth Factor A/metabolism ; Vascular Endothelial Growth Factor Receptor-1/genetics ; Vascular Endothelial Growth Factor Receptor-1/metabolism ; Vascular Endothelial Growth Factor Receptor-2/genetics ; Vascular Endothelial Growth Factor Receptor-2/metabolism
    Chemical Substances Anti-Inflammatory Agents ; Drugs, Chinese Herbal ; RNA, Messenger ; Taohong Siwu decoction II ; Vascular Endothelial Growth Factor A ; vascular endothelial growth factor A, mouse ; Carbon Tetrachloride (CL2T97X0V0) ; Vascular Endothelial Growth Factor Receptor-1 (EC 2.7.10.1) ; Vascular Endothelial Growth Factor Receptor-2 (EC 2.7.10.1) ; Proto-Oncogene Proteins c-akt (EC 2.7.11.1)
    Language English
    Publishing date 2016-03-02
    Publishing country Ireland
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 134511-4
    ISSN 1872-7573 ; 0378-8741
    ISSN (online) 1872-7573
    ISSN 0378-8741
    DOI 10.1016/j.jep.2016.01.030
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  6. Article: Tao-Phos-controlled desymmetrization of succinimide-based bisalkynes via asymmetric copper-catalyzed Huisgen alkyne–azide click cycloaddition: substrate scope and mechanism

    Chen, Mu-Yi / Song, Tao / Zheng, Zhan-Jiang / Xu, Zheng / Cui, Yu-Ming / Xu, Li-Wen

    RSC advances. 2016 June 20, v. 6, no. 63

    2016  

    Abstract: ... to 97% ee), in which the CuF2/Tao-Phos complex was proved to be an effective bimetallic catalyst ... on stereoselectivity as well as ESI-MS analysis suggested that our ligand (Tao-Phos) and related binuclear copper ...

    Abstract It was found that the catalytic Huisgen cycloaddition reaction of succinimide-derived bisalkynes with azides resulted in useful succinimide-derived triazoles bearing quaternary carbon-stereogenic centers with good to excellent yields as well as good chemoselectivity and moderate to high enantioselectivities (up to 97% ee), in which the CuF2/Tao-Phos complex was proved to be an effective bimetallic catalyst in the presence of triethylamine. The mechanistic studies based on the effect of reaction parameters on stereoselectivity as well as ESI-MS analysis suggested that our ligand (Tao-Phos) and related binuclear copper centers play a crucial role in this asymmetric click chemistry because of the strong catalyst–substrate interaction with the aid of a possibly in situ formed binuclear or multinuclear copper-based transition state. This work not only provides a new example of a Cu(ii)-mediated asymmetric AAC reaction involving chelating base and azides, but also suggests the significance of binuclear copper species in catalytic asymmetric click reactions with two copper center-involved enantioselective inductions.
    Keywords azides ; catalysts ; chemoselectivity ; copper ; cycloaddition reactions ; electrospray ionization mass spectrometry ; enantioselectivity ; ligands ; triazoles ; triethylamine
    Language English
    Dates of publication 2016-0620
    Size p. 58698-58708.
    Publishing place The Royal Society of Chemistry
    Document type Article
    ISSN 2046-2069
    DOI 10.1039/c6ra13687g
    Database NAL-Catalogue (AGRICOLA)

    More links

    Kategorien

  7. Article: Constructing Rh–Rh³⁺ modified Ta₂O₅@TaON@Ta₃N₅ with special double n–n mutant heterojunctions for enhanced photocatalytic H₂-evolution

    Zhang, Wenli / Jiang, Hongquan / Zhang, Wei / Zang, Shuying

    RSC advances. 2020 Aug. 10, v. 10, no. 49

    2020  

    Abstract: A multiple core–shell heterostructure Rh–Rh³⁺ modified Ta₂O₅@TaON@Ta₃N₅ nanophotocatalyst was ... successfully constructed through nitriding Rh³⁺-doped Ta₂O₅ nanoparticles, which exhibited a much higher ... carrier separation efficiency about one order of magnitude higher than the Ta₂O₅@Ta₃N₅ precursor, and ...

    Abstract A multiple core–shell heterostructure Rh–Rh³⁺ modified Ta₂O₅@TaON@Ta₃N₅ nanophotocatalyst was successfully constructed through nitriding Rh³⁺-doped Ta₂O₅ nanoparticles, which exhibited a much higher carrier separation efficiency about one order of magnitude higher than the Ta₂O₅@Ta₃N₅ precursor, and thus an excellent visible light photocatalytic H₂-evolution activity (83.64 μmol g⁻¹ h⁻¹), much superior to that of Rh anchored Ta₂O₅@TaON (39.41 μmol g⁻¹ h⁻¹), and improved stability due to the residual Rh–O/N in the Ta₃N₅ shell layer. Rh-modifying significantly extended light absorption to the overall visible region. Localized built-in electric fields with hierarchical potential gradients at the multiple interfaces including a Rh/Ta₃N₅ Schottky junction and double n–n Ta₃N₅/TaON/Ta₂O₅ mutant heterojunctions, drove charge carriers to directionally transfer from inside to outside, and efficiently separate. Enhanced photoactivity was ascribed to a synergetic effect of improved light absorption ability, increased carrier separation efficiency, and accelerated surface reaction. A promising strategy of developing excellent Ta₃N₅-based photocatalysts for solar energy conversion is provided by constructing double n–n mutant heterojunctions.
    Keywords absorption ; energy conversion ; light ; mutants ; photocatalysis ; photocatalysts ; solar energy ; synergism
    Language English
    Dates of publication 2020-0810
    Size p. 29424-29431.
    Publishing place The Royal Society of Chemistry
    Document type Article
    Note NAL-AP-2-clean
    ISSN 2046-2069
    DOI 10.1039/d0ra02214d
    Database NAL-Catalogue (AGRICOLA)

    More links

    Kategorien

  8. Article ; Online: A new species of Chucallis Tao (Hemiptera, Aphididae, Calaphidinae) from China.

    Jiang, Li-Yun / Chen, Jing / Qiao, Ge-Xia

    ZooKeys

    2011  , Issue 146, Page(s) 69–81

    Abstract: A new species in the aphid genus Chucallis Tao, Chucallis latusigladius Qiao, Jiang & Chen, sp. n ...

    Abstract A new species in the aphid genus Chucallis Tao, Chucallis latusigladius Qiao, Jiang & Chen, sp. n. feeding on a species of bamboo, Indocalamus tessellatus (Munro) Keng f., is described. It differs from the only other known species in the genus by having remarkably large marginal processes on abdominal tergite IV. A key to species, morphological descriptions, distributional data and host plant information are provided. The type specimens studied are deposited in the National Zoological Museum of China, Institute of Zoology, Chinese Academy of Sciences, Beijing, China.
    Language English
    Publishing date 2011-11-09
    Publishing country Bulgaria
    Document type Journal Article
    ZDB-ID 2445640-8
    ISSN 1313-2970 ; 1313-2989
    ISSN (online) 1313-2970
    ISSN 1313-2989
    DOI 10.3897/zookeys.146.2042
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  9. Article: The effects of Tao-Hong-Si-Wu on hepatic necroinflammatory activity and fibrosis in a murine model of chronic liver disease

    Xi, Shengyan / Gerald Y. Minuk / Jiaqi Yang / Lifeng Yue / Mengmeng Shi / Xinrong Wang / Xueqiang Jiang / Yangxinzi Xu / Yanhui Wang / Yao Cheng / Ying Peng / Yuewen Gong

    Journal of ethnopharmacology. 2016 Mar. 02, v. 180

    2016  

    Abstract: Tao-Hong-Si-Wu decoction (THSWD) is a traditional Chinese herbal medicine that has been used ...

    Abstract Tao-Hong-Si-Wu decoction (THSWD) is a traditional Chinese herbal medicine that has been used for centuries in the treatment of Chinese patients with chronic liver disease. Recently, THSWD has been reported to alter vascular endothelial growth factor (VEGF) induced angiogenesis, raising the possibility that in addition to its anti-inflammatory properties; THSWD might also inhibit hepatic blood flow associated fibrosis.To document the effects of THSWD on hepatic necroinflammatory disease activity, fibrosis and VEGF signaling in a murine model of chronic liver disease.Sixty adult mice were equally divided into six study groups. Five groups were exposed to subcutaneous carbon tetrachloride (0.1ml/10g BW) for six weeks. Three of the five groups were treated with different concentrations of THSWD (4.25, 8.50, 17.00g/kg), one with 0.1mg/kg of Colchicine (positive control), and one with physiologic saline (negative control). Mice in the sixth group were not exposed to CCl4 and remained untreated (healthy controls). Liver enzymes/function tests, hyaluronic acid and laminin levels were measured in serum, and hepatic histology, VEGF, Flt-1 and kinase insert domain-containing receptor (KDR), Akt and phosphorylated Akt (pAkt) expression were documented in liver tissue at the end of treatment.Hepatic necroinflammatory disease activity and fibrosis were significantly attenuated in THSWD treated mice in a dose dependent manner. These beneficial results were similar and often exceeded those achieved with Colchicine. In addition, VEGF, Flt-1, KDR, Akt and pAkt mRNA and protein expression were reduced in TSHWD treated mice.In this animal model of chronic liver disease, THSWD decreased hepatic necroinflammatory disease and fibrosis. Inhibition of VEGF expression and downstream signaling were associated with these findings. Further studies with this and other TCMs as treatment for chronic liver disease are warranted.
    Keywords adults ; angiogenesis ; animal models ; anti-inflammatory activity ; blood flow ; blood serum ; carbon tetrachloride ; colchicine ; dose response ; enzymes ; fibrosis ; histology ; hyaluronic acid ; laminin ; liver ; liver diseases ; messenger RNA ; mice ; Oriental traditional medicine ; patients ; protein synthesis ; vascular endothelial growth factors
    Language English
    Dates of publication 2016-0302
    Size p. 28-36.
    Publishing place Elsevier Ireland Ltd
    Document type Article
    ZDB-ID 134511-4
    ISSN 1872-7573 ; 0378-8741
    ISSN (online) 1872-7573
    ISSN 0378-8741
    DOI 10.1016/j.jep.2016.01.030
    Database NAL-Catalogue (AGRICOLA)

    More links

    Kategorien

  10. Article ; Online: Defect structure, phase separation, and electrical properties of nonstoichiometric tetragonal tungsten bronze Ba(0.5-x)TaO(3-x).

    Kuang, Xiaojun / Pan, Fengjuan / Cao, Jiang / Liang, Chaolun / Suchomel, Matthew R / Porcher, Florence / Allix, Mathieu

    Inorganic chemistry

    2013  Volume 52, Issue 22, Page(s) 13244–13252

    Abstract: New insight into the defect chemistry of the tetragonal tungsten bronze (TTB) Ba(0.5-x)TaO(3-x) is ... defect stoichiometries. The highly nonstoichiometric TTB Ba(0.5-x)TaO(3-x) (x = 0.25-0.325) compositions ... are stabilized via the interpolation of Ba(2+) cations and (TaO)(3+) groups into pentagonal tunnels ...

    Abstract New insight into the defect chemistry of the tetragonal tungsten bronze (TTB) Ba(0.5-x)TaO(3-x) is established here, which is shown to adapt to a continuous and extensive range of both cationic and anionic defect stoichiometries. The highly nonstoichiometric TTB Ba(0.5-x)TaO(3-x) (x = 0.25-0.325) compositions are stabilized via the interpolation of Ba(2+) cations and (TaO)(3+) groups into pentagonal tunnels, forming distinct Ba chains and alternate Ta-O rows in the pentagonal tunnels along the c axis. The slightly nonstoichiometric Ba(0.5-x)TaO(3-x) (x = 0-0.1) compositions incorporate framework oxygen and tunnel cation deficiencies in the TTB structure. These two mechanisms result in phase separation within the 0.1< x < 0.25 nonstoichiometric range, resulting in two closely related (TaO)(3+)-containing and (TaO)(3+)-free TTB phases. The highly nonstoichiometric (TaO)(3+)-containing phase exhibits Ba(2+) cationic migration. The incorporation of (TaO)(3+) units into the pentagonal tunnel and the local relaxation of the octahedral framework around the (TaO)(3+) units are revealed by diffraction data analysis and are shown to affect the transport and polarization properties of these compositions.
    Language English
    Publishing date 2013-11-18
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1484438-2
    ISSN 1520-510X ; 0020-1669
    ISSN (online) 1520-510X
    ISSN 0020-1669
    DOI 10.1021/ic402188x
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

To top