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  1. Book: 30 years of research and innovation with recombinant activated factor VII (eptacog alfa activated)

    Mannucci, Pier M.

    (Blood reviews ; 29, Suppl. 1)

    2015  

    Title variant Thirty years of research and innovation with recombinant activated factor VII (eptacog alfa activated)
    Author's details guest ed.: Pier Mannuccio Mannucci
    Series title Blood reviews ; 29, Suppl. 1
    Collection
    Language English
    Size S41S. : graph. Darst.
    Publisher Elsevier
    Publishing place Amsterdam u.a.
    Publishing country Netherlands
    Document type Book
    HBZ-ID HT018766652
    Database Catalogue ZB MED Medicine, Health

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    Zs A 2207 -29,Suppl.1- not available for loan Zeitschriften-Lesesaal

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  2. Book ; Conference proceedings: The start of a new era for antithrombotic agents

    Mannucci, Pier M.

    abstracts from the 21st International Congress on Thrombosis, Milan, Italy, July 6 - 9, 2010

    (Pathophysiology of haemostasis and thrombosis ; 37, Suppl. 1)

    2010  

    Institution Mediterranean League against Thromboembolic Diseases
    Event/congress International Congress on Thrombosis (21., 2010, Mailand)
    Author's details guest ed. P. M. Mannucci. [Organized by the Mediterranean League against Thromboembolic Diseases]
    Series title Pathophysiology of haemostasis and thrombosis ; 37, Suppl. 1
    Collection
    Keywords Thrombose
    Subject Thrombosen
    Subject code 616.135
    Language English
    Size [326] S. in getr. Zählung : Ill., graph. Darst.
    Publisher Karger
    Publishing place Basel u.a.
    Publishing country Switzerland
    Document type Book ; Conference proceedings
    HBZ-ID HT016752801
    ISBN 978-3-8055-9388-5 ; 3-8055-9388-0
    Database Catalogue ZB MED Medicine, Health

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  3. Book: Desmopressin (DDAVP): the first thirty years

    Mannucci, Pier M.

    (Haemophilia ; 14, Suppl. 1)

    2008  

    Author's details guest ed.: P. M. Mannucci
    Series title Haemophilia ; 14, Suppl. 1
    Collection
    Language English
    Size 47 S. : Ill., graph. Darst.
    Publisher Blackwell
    Publishing place Oxford
    Publishing country Great Britain
    Document type Book
    HBZ-ID HT015432009
    Database Catalogue ZB MED Medicine, Health

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  4. Book: Von Willebrand factor in high purity FVIII complex concentrates

    Mannucci, Pier M.

    chaperon protein or key to therapies?

    (Haemophilia ; 13, Suppl. 5)

    2007  

    Author's details Guest ed.:P. M. Mannucci
    Series title Haemophilia ; 13, Suppl. 5
    Collection
    Language English
    Size 77 S. : graph. Darst.
    Publisher Blackwell
    Publishing place Oxford
    Publishing country Great Britain
    Document type Book
    HBZ-ID HT015411982
    Database Catalogue ZB MED Medicine, Health

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  5. Article ; Online: Editorial.

    Mannucci, P M

    Journal of thrombosis and haemostasis : JTH

    2018  Volume 4, Issue 1, Page(s) 1–2

    Language English
    Publishing date 2018-04-01
    Publishing country England
    Document type Editorial
    ZDB-ID 2112661-6
    ISSN 1538-7836 ; 1538-7933
    ISSN (online) 1538-7836
    ISSN 1538-7933
    DOI 10.1111/j.1538-7836.2005.01773.x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.MO 295: Show issues

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  6. Article ; Online: Viral safety of coagulation factor concentrates: memoirs from an insider.

    Mannucci, P M

    Journal of thrombosis and haemostasis : JTH

    2018  Volume 16, Issue 4, Page(s) 630–633

    Abstract: The purpose of this essay is to recall the actions taken globally to improve the viral safety of coagulation factor concentrates, mainly in the years 1985-1990, at a time of confusing and often contradictory information on bloodborne viral infections in ... ...

    Abstract The purpose of this essay is to recall the actions taken globally to improve the viral safety of coagulation factor concentrates, mainly in the years 1985-1990, at a time of confusing and often contradictory information on bloodborne viral infections in multitransfused patients with hemophilia (PWHs). I shall first recall the problem of the transmission and control of the hepatitis viruses, and then that of HIV: not only for temporal reasons, but also because understanding the progress of knowledge on hepatitis and the poor success of the early measures taken to tackle this problem in PWHs is essential to understand how the problem of HIV transmission was ultimately dealt with successfully.
    MeSH term(s) Blood Coagulation Factors/adverse effects ; Blood Coagulation Factors/history ; Coagulants/adverse effects ; Coagulants/history ; Drug Contamination/prevention & control ; HIV Infections/blood ; HIV Infections/history ; HIV Infections/transmission ; Hemophilia A/blood ; Hemophilia A/drug therapy ; Hemophilia A/history ; Hepatitis, Viral, Human/blood ; Hepatitis, Viral, Human/history ; Hepatitis, Viral, Human/transmission ; History, 20th Century ; Humans ; Patient Safety/history ; Recombinant Proteins/history ; Risk Assessment ; Risk Factors
    Chemical Substances Blood Coagulation Factors ; Coagulants ; Recombinant Proteins
    Language English
    Publishing date 2018-02-23
    Publishing country England
    Document type Historical Article ; Journal Article
    ZDB-ID 2112661-6
    ISSN 1538-7836 ; 1538-7933
    ISSN (online) 1538-7836
    ISSN 1538-7933
    DOI 10.1111/jth.13963
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.MO 295: Show issues

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  7. Article ; Online: Miracle of haemophilia drugs: Personal views about a few main players.

    Mannucci, P M

    Haemophilia : the official journal of the World Federation of Hemophilia

    2018  Volume 24, Issue 4, Page(s) 557–562

    Abstract: Introduction: In the second decade of the third millennium there have been dramatic developments pertaining to the availability of highly innovative drugs for hemophilia care, notwithstanding a satisfactory previous scenario.: Aim: I am going to ... ...

    Abstract Introduction: In the second decade of the third millennium there have been dramatic developments pertaining to the availability of highly innovative drugs for hemophilia care, notwithstanding a satisfactory previous scenario.
    Aim: I am going to emphasize the role of 2 main categories of players: scientist physicians who produced important translational research and the pharmaceutical industry, who developed, produced and made commercially available so many improved treatment weapons stemming from the translational research of the forementioned scientist physicians.
    Results: Pertaining to the role of scientist physicians, I chose to mention first those who were successful in the 1980 in the production of recombinant coagulation factors. In addition, those who more recently helped to produce new non substitutive therapies given by the subcutaneous route, and recombination coagulation factors with an extended half-life.
    Conclusions: Current miraculous progress in hemophilia therapy is stemming from the research work of outstanding scientist physicians who acted in close collaboration with small biotechnology companies, leading to the early development of innovative therapeutic products, subsequently taken to the market place by the so called Big Pharma. I shall briefly provide my views to explain the fact that large pharmaceutical companies show more and more interest in such a rare disease as the hemophilias.
    MeSH term(s) Animals ; Drug Discovery/methods ; Drug Industry ; Hemophilia A/drug therapy ; Hemophilia B/drug therapy ; Humans ; Translational Medical Research
    Language English
    Publishing date 2018-05-29
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 1229713-6
    ISSN 1365-2516 ; 1351-8216 ; 1355-0691
    ISSN (online) 1365-2516
    ISSN 1351-8216 ; 1355-0691
    DOI 10.1111/hae.13519
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.MO 450: Show issues

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  8. Article ; Online: Conceptualizing a model for European health systems: the institutional framework.

    Garattini, L / Freemantle, N / Nobili, A / Mannucci, P M

    Internal and emergency medicine

    2023  Volume 18, Issue 4, Page(s) 1213–1215

    MeSH term(s) Humans ; European Union ; Health Policy
    Language English
    Publishing date 2023-04-04
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 2454173-4
    ISSN 1970-9366 ; 1828-0447
    ISSN (online) 1970-9366
    ISSN 1828-0447
    DOI 10.1007/s11739-023-03261-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Guidance for the antithrombotic management of persons with haemophilia and cardiovascular disease.

    Mannucci, Pier Mannuccio / Agosti, Pasquale / Lettino, Maddalena

    Haemophilia : the official journal of the World Federation of Hemophilia

    2023  Volume 29, Issue 6, Page(s) 1390–1393

    MeSH term(s) Humans ; Cardiovascular Diseases/complications ; Cardiovascular Diseases/drug therapy ; Cardiovascular Diseases/prevention & control ; Hemophilia A/complications ; Hemophilia A/drug therapy ; Fibrinolytic Agents/therapeutic use
    Chemical Substances Fibrinolytic Agents
    Language English
    Publishing date 2023-09-20
    Publishing country England
    Document type Journal Article
    ZDB-ID 1229713-6
    ISSN 1365-2516 ; 1351-8216 ; 1355-0691
    ISSN (online) 1365-2516
    ISSN 1351-8216 ; 1355-0691
    DOI 10.1111/hae.14874
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Health technology assessment for pharmaceuticals in the European Union: what lessons after two decades?

    Garattini, L / Bozzetto, M / Nobili, A / Mannucci, P M

    Internal and emergency medicine

    2022  Volume 17, Issue 5, Page(s) 1251–1253

    MeSH term(s) European Union ; Health Policy ; Humans ; Pharmaceutical Preparations ; Technology Assessment, Biomedical
    Chemical Substances Pharmaceutical Preparations
    Language English
    Publishing date 2022-06-08
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 2454173-4
    ISSN 1970-9366 ; 1828-0447
    ISSN (online) 1970-9366
    ISSN 1828-0447
    DOI 10.1007/s11739-022-03008-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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