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  1. Article ; Online: Estado nutricional y funcionalidad, pareja estable siempre a considerar en nuestros mayores.

    Álvarez, Julia

    Nutricion hospitalaria

    2020  Volume 37, Issue 2, Page(s) 231–232

    Title translation Estado nutricional y funcionalidad, pareja estable siempre a considerar en nuestros mayores.
    Language Spanish
    Publishing date 2020-04-13
    Publishing country Spain
    Document type English Abstract ; Journal Article
    ZDB-ID 1481223-x
    ISSN 1699-5198 ; 0212-1611
    ISSN (online) 1699-5198
    ISSN 0212-1611
    DOI 10.20960/nh.03094
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 5078: Show issues Location:
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  2. Article ; Online: El músculo, nuevo paradigma en nutrición clínica.

    Álvarez, Julia

    Nutricion hospitalaria

    2019  Volume 36, Issue Spec No2, Page(s) 1–3

    Title translation Muscle, a new paradigm in clinical nutrition.
    MeSH term(s) Adult ; Aged ; Humans ; Middle Aged ; Muscle Strength ; Muscle, Skeletal/physiology ; Nutrition Therapy/trends ; Sarcopenia/prevention & control
    Language Spanish
    Publishing date 2019-06-17
    Publishing country Spain
    Document type Introductory Journal Article
    ZDB-ID 1481223-x
    ISSN 1699-5198 ; 0212-1611
    ISSN (online) 1699-5198
    ISSN 0212-1611
    DOI 10.20960/nh.02674
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Apuntes sobre el coste-efectividad de la terapia nutricional con suplementación oral en la recuperación integral del paciente con DRE.

    Álvarez, Julia

    Nutricion hospitalaria

    2019  Volume 36, Issue Spec No2, Page(s) 44–49

    Abstract: Introduction: The efficient management of health services requires obtaining the highest level of health possible with the available resources. The health economy has developed in recent years under the pressure of a more demanding population, older and ...

    Title translation Notes on the cost-effectiveness of nutritional therapy with oral supplementation in the integral recovery of the patient with MRD.
    Abstract Introduction: The efficient management of health services requires obtaining the highest level of health possible with the available resources. The health economy has developed in recent years under the pressure of a more demanding population, older and with more comorbidities, in an environment of limited resources and greater financing difficulties. The Economics of Nutrition was born as a new discipline that addresses aspects related to the role of economics and nutrition in the health of healthy and sick populations. The economic analyzes are part of the evaluation tools for health interventions. Cost-effectiveness studies are the most frequently used. Cost-effectiveness studies have shown that the use of oral nutritional supplements offer clinical advantages for undernourished patients (reduction of morbidity and mortality) and economic benefits for the system (reduction of hospital stay, lower re-entry rates and cost savings). Oral nutritional supplementation in the integral recovery of the patient with malnutrition related to the disease is cost effective.
    MeSH term(s) Adult ; Aged ; Aged, 80 and over ; Cost Savings ; Cost-Benefit Analysis ; Dietary Supplements ; Humans ; Malnutrition/complications ; Malnutrition/economics ; Malnutrition/therapy ; Middle Aged ; Neoplasm, Residual/therapy ; Nutrition Therapy/economics ; Nutritional Support
    Language Spanish
    Publishing date 2019-06-17
    Publishing country Spain
    Document type Journal Article ; Review
    ZDB-ID 1481223-x
    ISSN 1699-5198 ; 0212-1611
    ISSN (online) 1699-5198
    ISSN 0212-1611
    DOI 10.20960/nh.02682
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Investigación e innovación en nutrición enteral.

    Álvarez, Julia

    Nutricion hospitalaria

    2018  Volume 35, Issue Spec no2, Page(s) 1–3

    Title translation Research and innovation in enteral nutrition.
    MeSH term(s) Biomedical Research/trends ; Enteral Nutrition/trends ; Humans ; Research
    Language Spanish
    Publishing date 2018-04-03
    Publishing country Spain
    Document type Editorial
    ZDB-ID 1481223-x
    ISSN 1699-5198 ; 0212-1611
    ISSN (online) 1699-5198
    ISSN 0212-1611
    DOI 10.20960/nh.1953
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Screening of variables affecting the selective leaching of valuable metals from waste motherboards' PCBs.

    Rahimi, Vahid / Inzulza-Moraga, Emilio Antonio / Gómez-Díaz, Diego / Freire, María Sonia / González-Álvarez, Julia

    Environmental science and pollution research international

    2024  

    Abstract: The presence of valuable and hazardous metals in waste printed circuit boards, especially, motherboards, makes their recovery necessary as implies great economic and environmental advantages and develops urban mining processes. Hence, this research is ... ...

    Abstract The presence of valuable and hazardous metals in waste printed circuit boards, especially, motherboards, makes their recovery necessary as implies great economic and environmental advantages and develops urban mining processes. Hence, this research is focused on the selective leaching of Cu, Pb, and Sn as base metals using nitric acid and hydrochloric acid and Au, Ag, and Pd as precious metals using thiourea and sodium thiosulfate from waste motherboards' PCBs in a sequential eco-friendly two-stage process. Previously, thiourea and sodium thiosulfate were used as leaching agents to investigate their applicability for the leaching of metals from PCBs in a single-stage process. Screening experimental design was applied to screen the variables affecting the leaching process in order to evaluate their impact on the recovery of metals and select the significant factors. The results demonstrated that base and precious metals can be leached appropriately in two consecutive stages compared to a single-stage process. Nitric acid was found to be a much more efficient agent to leach Cu and Pb in comparison with hydrochloric acid which was more suitable for the leaching of Sn. In the case of precious metals, higher amounts of Au were leached using thiourea, whereas sodium thiosulfate was able to leach more Pd. Roughly similar results were obtained for the leaching of Ag using these leaching agents. Nitric acid concentration, average particle size, temperature, and leaching time were found to be significant to maximize the leaching of Cu and Pb and minimize that for Au, Ag, and Pd in the first stage. Initial pH was the only variable influencing the second stage, in particular, Au leaching by thiourea.
    Language English
    Publishing date 2024-03-09
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1178791-0
    ISSN 1614-7499 ; 0944-1344
    ISSN (online) 1614-7499
    ISSN 0944-1344
    DOI 10.1007/s11356-024-32793-1
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  6. Article ; Online: Ammonia surrogates in the synthesis of primary amines.

    Urbiña-Alvarez, Julia / Rincón-Carvajal, Sergio / Gamba-Sánchez, Diego

    Organic & biomolecular chemistry

    2023  Volume 21, Issue 35, Page(s) 7036–7051

    Abstract: Primary amines are derivatives of ammonia in which one hydrogen atom is replaced by an alkyl or aryl group. Ammonia serves as the primary nitrogen source in amination reactions, and its utilization in solution or as a pure gas has witnessed notable ... ...

    Abstract Primary amines are derivatives of ammonia in which one hydrogen atom is replaced by an alkyl or aryl group. Ammonia serves as the primary nitrogen source in amination reactions, and its utilization in solution or as a pure gas has witnessed notable advancements. However, the use of gaseous ammonia remains problematic in academic laboratory settings, while employing aqueous ammonia poses challenges in highly water-sensitive transformations. Consequently, the search for alternative sources of ammonia has garnered considerable attention among the organic chemistry community. This comprehensive literature review focuses on the use of ammonia surrogates in amination reactions, irrespective of the resulting intermediate. The review emphasizes the formation of the C-N bond and underscores the importance of generating intermediate products that can be readily transformed into primary amines through well-established reactions.
    Language English
    Publishing date 2023-09-13
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2097583-1
    ISSN 1477-0539 ; 1477-0520
    ISSN (online) 1477-0539
    ISSN 1477-0520
    DOI 10.1039/d3ob01202f
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Removal of copper from aqueous solutions by biosorption onto pine sawdust

    Orozco, Clara Isabel / Freire, M. Sonia / Gómez-Díaz, Diego / González-Álvarez, Julia

    Sustainable Chemistry and Pharmacy. 2023 May, v. 32 p.101016-

    2023  

    Abstract: Untreated Pinus radiata sawdust was investigated for the removal of Cu⁺² ions from aqueous solutions. The biomass was characterized by Inductively Coupled Plasma-Mass (ICP-MS) spectrometry and by Scanning Electron Microscopy with an Energy Dispersive X- ... ...

    Abstract Untreated Pinus radiata sawdust was investigated for the removal of Cu⁺² ions from aqueous solutions. The biomass was characterized by Inductively Coupled Plasma-Mass (ICP-MS) spectrometry and by Scanning Electron Microscopy with an Energy Dispersive X-ray spectroscopy (SEM-EDX), X-Ray crystalline powder Diffraction (XRD) and Fourier Transform Infrared (FTIR) spectroscopy, before and after adsorption. The influence of contact time (up to equilibrium), adsorbent dose (1–50 g/L), initial metal ion concentration (5–300 mg/L) and pH (2–8) on copper sorption efficiency was studied through batch experiments. The results demonstrated that adsorption equilibrium is reached in less than 2 h and the best conditions (Cu⁺² removal percentage, 93.4% and adsorption capacity, 0.82 mg/g) were achieved by increasing the adsorbent dose up to 5 g/L and the solution pH up to 7, and decreasing the initial metal concentration to 5 mg/L. The adsorption was optimized by means of a Doehlert experimental design analyzing the influence of adsorbent dose (5–15 g/L) and copper initial concentration (5–45 mg/L) on adsorption efficiency. Kinetic data were satisfactorily fitted to the second-order kinetic model. Intraparticle diffusion model demonstrated that different stages are involved in the adsorption process. Langmuir isotherms fitted satisfactorily the copper bioadsorption equilibrium data. Desorption studies achieved high efficiencies up to 94.5% and the possibility of sawdust regeneration was studied with four adsorption-desorption cycles. Thus, this study evidenced that sawdust is a promising efficient, renewable and economic adsorbent for metal removal and its use for that purpose constitutes an alternative for its management and valorization.
    Keywords Fourier transform infrared spectroscopy ; Pinus radiata ; X-radiation ; adsorbents ; adsorption ; biomass ; biosorption ; copper ; desorption ; electron microscopy ; energy-dispersive X-ray analysis ; experimental design ; green chemistry ; kinetics ; models ; pH ; sawdust ; Heavy metal
    Language English
    Dates of publication 2023-05
    Publishing place Elsevier B.V.
    Document type Article ; Online
    Note Use and reproduction
    ISSN 2352-5541
    DOI 10.1016/j.scp.2023.101016
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  8. Article ; Online: S/N/O-Enriched Carbons from Polyacrylonitrile-Based Block Copolymers for Selective Separation of Gas Streams.

    Gómez-Díaz, Diego / Domínguez-Ramos, Lidia / Malucelli, Giulio / Freire, María Sonia / González-Álvarez, Julia / Lazzari, Massimo

    Polymers

    2024  Volume 16, Issue 2

    Abstract: A series of polyacrylonitrile (PAN)-based block copolymers with poly(methyl methacrylate) (PMMA) as sacrificial bock were synthesized by atom transfer radical polymerization and used as precursors for the synthesis of porous carbons. The carbons enriched ...

    Abstract A series of polyacrylonitrile (PAN)-based block copolymers with poly(methyl methacrylate) (PMMA) as sacrificial bock were synthesized by atom transfer radical polymerization and used as precursors for the synthesis of porous carbons. The carbons enriched with O- and S-containing groups, introduced by controlled oxidation and sulfuration, respectively, were characterized by Raman spectroscopy, scanning electron microscopy, and X-ray photoelectron spectrometry, and their surface textural properties were measured by a volumetric analyzer. We observed that the presence of sulfur tends to modify the structure of the carbons, from microporous to mesoporous, while the use of copolymers with a range of molar composition PAN/PMMA between 10/90 and 47/53 allows the obtainment of carbons with different degrees of porosity. The amount of sacrificial block only affects the morphology of carbons stabilized in oxygen, inducing their nanostructuration, but has no effect on their chemical composition. We also demonstrated their suitability for separating a typical N
    Language English
    Publishing date 2024-01-18
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2527146-5
    ISSN 2073-4360 ; 2073-4360
    ISSN (online) 2073-4360
    ISSN 2073-4360
    DOI 10.3390/polym16020269
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  9. Article ; Online: Neuronal filopodium formation induced by the membrane glycoprotein M6a (Gpm6a) is facilitated by coronin-1a, Rac1, and p21-activated kinase 1 (Pak1).

    Alvarez Juliá, Anabel / Frasch, Alberto C / Fuchsova, Beata

    Journal of neurochemistry

    2016  Volume 137, Issue 1, Page(s) 46–61

    Abstract: Stress-responsive neuronal membrane glycoprotein M6a (Gpm6a) functions in neurite extension, filopodium and spine formation and synaptogenesis. The mechanisms of Gpm6a action in these processes are incompletely understood. Previously, we identified the ... ...

    Abstract Stress-responsive neuronal membrane glycoprotein M6a (Gpm6a) functions in neurite extension, filopodium and spine formation and synaptogenesis. The mechanisms of Gpm6a action in these processes are incompletely understood. Previously, we identified the actin regulator coronin-1a (Coro1a) as a putative Gpm6a interacting partner. Here, we used co-immunoprecipitation assays with the anti-Coro1a antibody to show that Coro1a associates with Gpm6a in rat hippocampal neurons. By immunofluorescence microscopy, we demonstrated that in hippocampal neurons Coro1a localizes in F-actin-enriched regions and some of Coro1a spots co-localize with Gpm6a labeling. Notably, the over-expression of a dominant-negative form of Coro1a as well as its down-regulation by siRNA interfered with Gpm6a-induced filopodium formation. Coro1a is known to regulate the plasma membrane translocation and activation of small GTPase Rac1. We show that Coro1a co-immunoprecipitates with Rac1 together with Gpm6a. Pharmacological inhibition of Rac1 resulted in a significant decrease in filopodium formation by Gpm6a. The same was observed upon the co-expression of Gpm6a with the inactive GDP-bound form of Rac1. In this case, the elevated membrane recruitment of GDP-bound Rac1 was detected as well. Moreover, the kinase activity of the p21-activated kinase 1 (Pak1), a main downstream effector of Rac1 that acts downstream of Coro1a, was required for Gpm6a-induced filopodium formation. Taken together, our results provide evidence that a signaling pathway including Coro1a, Rac1, and Pak1 facilitates Gpm6a-induced filopodium formation. Formation of filopodia by membrane glycoprotein M6a (Gpm6a) requires actin regulator coronin-1a (Coro1a), known to regulate plasma membrane localization and activation of Rac1 and its downstream effector Pak1. Coro1a associates with Gpm6a. Blockage of Coro1a, Rac1, or Pak1 interferes with Gpm6a-induced filopodium formation. Moreover, Gpm6a facilitates Rac1 membrane recruitment. Altogether, a mechanistic insight into the process of Gpm6a-induced neuronal filopodium formation is provided.
    MeSH term(s) Actins/analysis ; Animals ; Cells, Cultured ; Down-Regulation ; Genes, Reporter ; Hippocampus/cytology ; Membrane Glycoproteins/physiology ; Microfilament Proteins/genetics ; Microfilament Proteins/physiology ; Nerve Tissue Proteins/antagonists & inhibitors ; Nerve Tissue Proteins/physiology ; Neurons/ultrastructure ; Organelle Biogenesis ; Primary Cell Culture ; Pseudopodia/physiology ; RNA, Small Interfering/genetics ; Rats ; Rats, Sprague-Dawley ; Signal Transduction/drug effects ; Signal Transduction/physiology ; p21-Activated Kinases/physiology ; rac1 GTP-Binding Protein/antagonists & inhibitors ; rac1 GTP-Binding Protein/physiology
    Chemical Substances Actins ; Gpm6a protein, rat ; Membrane Glycoproteins ; Microfilament Proteins ; Nerve Tissue Proteins ; RNA, Small Interfering ; coronin proteins (145420-64-0) ; Pak1 protein, rat (EC 2.7.11.1) ; p21-Activated Kinases (EC 2.7.11.1) ; Rac1 protein, rat (EC 3.6.1.-) ; rac1 GTP-Binding Protein (EC 3.6.5.2)
    Language English
    Publishing date 2016-04
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 80158-6
    ISSN 1471-4159 ; 0022-3042 ; 1474-1644
    ISSN (online) 1471-4159
    ISSN 0022-3042 ; 1474-1644
    DOI 10.1111/jnc.13552
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    Ui II Zs.170: Show issues Location:
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  10. Article ; Online: Forest by-Product Valorization: Pilot-Scale Pinus radiata and Eucalyptus globulus Bark Mixture Extraction

    Santos, Jorge / Escobar-Avello, Danilo / Fuentealba, Cecilia / Cabrera-Barjas, Gustavo / González-Álvarez, Julia / Martins, Jorge M. / Carvalho, Luisa H.

    Forests. 2023 Apr. 26, v. 14, no. 5

    2023  

    Abstract: One of the most important by-products generated in the forestry industry is the bark obtained during the debarking process. Pine (Pinus radiata D. Don) and eucalyptus (Eucalyptus globulus L.) are the main important tree species exploited in the Chilean ... ...

    Abstract One of the most important by-products generated in the forestry industry is the bark obtained during the debarking process. Pine (Pinus radiata D. Don) and eucalyptus (Eucalyptus globulus L.) are the main important tree species exploited in the Chilean forestry industry. The bark of P. radiata D. Don is an interesting source of extracts, rich in condensed tannins, with potential uses in biopolymer and bioadhesive preparation. Conversely, the E. globulus bark extracts are rich in hydrolyzable tannins with few applications. Nevertheless, the forest industry generates a high volume of these by-products, simultaneously. Then, it is interesting to determine a suitable process for the joint valorization of both forest by-products at a large scale. In this work, alkaline extraction (NaOH and Na₂SO₃) was performed at a pilot scale of a mixture of E. globulus and P. radiata barks prepared at different ratios (0%–100%). The effect of bark mixture composition on the resulting extract’s properties was evaluated. All extracts were characterized according to their chemical composition by FTIR-ATR, MALDI-TOF, and molecular weight distribution (GPC). In addition, the Stiasny number was tested to determine the potential use of extracts in bioadhesive formulation. The self-condensation reaction of resulting extracts was studied using Dynamic Mechanical Analysis (DMA) and Automated Bond Evaluation System (ABES) techniques. Results show a good interaction between condensed and hydrolyzable tannins from both species’ barks. It also demonstrated the potential application of the obtained extracts, for a bark ratio of 50:50, in the formulation of bioadhesives for particleboard manufacture. The obtained product showed a similar performance to that of the bioadhesive formulated with the extract obtained using only P. radiata bark.
    Keywords Eucalyptus globulus ; Pinus radiata ; bark ; bioadhesives ; chemical composition ; forest industries ; forests ; manufacturing ; molecular weight ; particleboards ; plant byproducts ; trees
    Language English
    Dates of publication 2023-0426
    Publishing place Multidisciplinary Digital Publishing Institute
    Document type Article ; Online
    ZDB-ID 2527081-3
    ISSN 1999-4907
    ISSN 1999-4907
    DOI 10.3390/f14050895
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