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  1. Article ; Online: Adjuvant immunotherapy in muscle-invasive bladder cancer: Closer than it seems?

    Pinto, Á / Álvarez-Maestro, M

    Actas urologicas espanolas

    2021  

    Title translation Inmunoterapia adyuvante en cáncer de vejiga músculo-invasivo: ¿más cerca de lo que parece?
    Language Spanish
    Publishing date 2021-07-27
    Publishing country Spain
    Document type Editorial
    ISSN 2173-5786
    ISSN (online) 2173-5786
    DOI 10.1016/j.acuro.2021.05.003
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Are we at the end of adjuvant radiotherapy for prostate cancer?

    Couñago, F / Alvarez-Maestro, M

    Actas urologicas espanolas

    2021  

    Title translation ¿Estamos ante el final de la radioterapia adyuvante en cáncer de próstata?
    Language Spanish
    Publishing date 2021-05-12
    Publishing country Spain
    Document type Editorial
    ISSN 2173-5786
    ISSN (online) 2173-5786
    DOI 10.1016/j.acuro.2021.03.004
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Are we at the end of adjuvant radiotherapy for prostate cancer?

    Couñago, F / Alvarez-Maestro, M

    Actas urologicas espanolas

    2021  Volume 45, Issue 8, Page(s) 521–523

    MeSH term(s) Humans ; Male ; Prostatectomy ; Prostatic Neoplasms/radiotherapy ; Radiotherapy, Adjuvant
    Language Spanish
    Publishing date 2021-09-17
    Publishing country Spain
    Document type Editorial
    ISSN 2173-5786
    ISSN (online) 2173-5786
    DOI 10.1016/j.acuroe.2021.07.007
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  4. Article ; Online: Adjuvant immunotherapy in muscle-invasive bladder cancer: Closer than it seems?

    Pinto, Á / Álvarez-Maestro, M

    Actas urologicas espanolas

    2021  Volume 45, Issue 9, Page(s) 567–568

    MeSH term(s) Cystectomy ; Humans ; Immunotherapy ; Muscles ; Urinary Bladder Neoplasms/therapy
    Language Spanish
    Publishing date 2021-10-21
    Publishing country Spain
    Document type Editorial
    ISSN 2173-5786
    ISSN (online) 2173-5786
    DOI 10.1016/j.acuroe.2021.10.001
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  5. Article ; Online: Conservative management of high-grade renal trauma.

    Aguilera Bazán, A / Yebes, Á / Álvarez-Maestro, M / Díez, J / Samblás, M / Martínez Piñeiro, L

    Actas urologicas espanolas

    2024  

    Abstract: Introduction: Renal trauma is the most common of urological trauma and accounts for up to 5% of all. The AAST scale is the most widely used to assess renal trauma. This study focuses on high-grade trauma, whose treatment has evolved towards a ... ...

    Abstract Introduction: Renal trauma is the most common of urological trauma and accounts for up to 5% of all. The AAST scale is the most widely used to assess renal trauma. This study focuses on high-grade trauma, whose treatment has evolved towards a conservative approach, with techniques such as angioembolization. The aim is to describe the evolution in the management of high-grade renal trauma in all patients treated at La Paz University Hospital from 2001 to 2022.
    Methods: A descriptive retrospective study was conducted on patients treated at the hospital. The study was divided into two periods (2001-2010 and 2011-2022). A total of 285 patients with renal trauma were collected, of which 54 were high grade. The main variable is the type of management, conservative (embolization) or interventional through nephrectomy.
    Results: In the completed series, there was a decrease in radical nephrectomy in high-grade renal trauma from 50% to 13.8% over time, with an increase in embolization from 23,1% to 44,8%. In patients with isolated renal trauma, those treated with embolization increased from 28.6% to 69.2%, while those undergoing radical/partial nephrectomy decreased from 42.8% to 7.69%.
    Conclusion: The management of renal trauma has evolved over the years in our center. The number of patients treated by embolization has increased, while the number of complications and nephrectomies has decreased.
    Language Spanish
    Publishing date 2024-02-16
    Publishing country Spain
    Document type Journal Article
    ISSN 2173-5786
    ISSN (online) 2173-5786
    DOI 10.1016/j.acuroe.2024.02.011
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  6. Article ; Online: Surgery for oligometastatic prostate cancer: Where are we going?

    Alvarez-Maestro, M / Gomez Rivas, J / Moschini, M

    Actas urologicas espanolas

    2021  Volume 45, Issue 7, Page(s) 479–480

    MeSH term(s) Humans ; Male ; Prostatic Neoplasms/surgery
    Language Spanish
    Publishing date 2021-07-28
    Publishing country Spain
    Document type Editorial
    ISSN 2173-5786
    ISSN (online) 2173-5786
    DOI 10.1016/j.acuroe.2021.06.006
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Multidisciplinary consensus document on the current treatment of bacille Calmette-Guérin-unresponsive non-muscle invasive bladder tumor.

    Guerrero-Ramos, F / Álvarez-Maestro, M / Pinto Marín, Á / Domínguez Escrig, J L / Rodríguez Faba, Ó

    Actas urologicas espanolas

    2024  Volume 48, Issue 4, Page(s) 262–272

    Abstract: Radical cystectomy is the current treatment of choice for patients with BCG-unresponsive non-muscle invasive bladder tumor (NMIBC). However, the high comorbidity of this surgery and its effects on the quality of life of patients require the investigation ...

    Abstract Radical cystectomy is the current treatment of choice for patients with BCG-unresponsive non-muscle invasive bladder tumor (NMIBC). However, the high comorbidity of this surgery and its effects on the quality of life of patients require the investigation and implementation of bladder-sparing treatment options. These must be evaluated individually by the uro-oncology committee based on the characteristics of the BCG failure, type of tumor, patient preferences and treatment options available in each center. Based on FDA-required oncologic outcomes (6-month complete response rate for CIS: 50%; duration of response in responders for CIS and papillary: 30% at 12 months and 25% at 18 months), there is not currently a strong preference for one treatment over another, although the intravesical route seems to offer less toxicity. This work summarizes the evidence on the management of BCG-unresponsive NMIBC based on current scientific evidence and provides consensus recommendations on the most appropriate treatment.
    MeSH term(s) Urinary Bladder Neoplasms/pathology ; Urinary Bladder Neoplasms/drug therapy ; Urinary Bladder Neoplasms/therapy ; Humans ; BCG Vaccine/therapeutic use ; BCG Vaccine/administration & dosage ; Neoplasm Invasiveness ; Adjuvants, Immunologic/therapeutic use ; Cystectomy/methods ; Treatment Failure ; Administration, Intravesical ; Consensus
    Chemical Substances BCG Vaccine ; Adjuvants, Immunologic
    Language Spanish
    Publishing date 2024-04-02
    Publishing country Spain
    Document type Journal Article ; Consensus Development Conference ; Practice Guideline
    ISSN 2173-5786
    ISSN (online) 2173-5786
    DOI 10.1016/j.acuroe.2024.04.005
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  8. Article ; Online: The need of avoiding unnecessary biopsies in active surveillance for prostate cancer.

    Taratkin, M / Álvarez-Maestro, M / Gómez Rivas, J

    Actas urologicas espanolas

    2021  Volume 45, Issue 6, Page(s) 417–418

    MeSH term(s) Biopsy ; Humans ; Male ; Prostatic Neoplasms/diagnosis ; Watchful Waiting
    Language Spanish
    Publishing date 2021-06-16
    Publishing country Spain
    Document type Editorial
    ISSN 2173-5786
    ISSN (online) 2173-5786
    DOI 10.1016/j.acuroe.2021.02.008
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Is trimodal therapy the current standard for muscle-invasive bladder cancer?

    López Valcárcel, M / Barrado Los Arcos, M / Ferri Molina, M / Cienfuegos Belmonte, I / Duque Santana, V / Gajate Borau, P / Fernández Ibiza, J / Álvarez Maestro, M / Sargos, P / López Campos, F / Couñago, F

    Actas urologicas espanolas

    2024  

    Abstract: Objective: The aim of this review is to summarize the current evidence and future perspectives of bladder-sparing treatment for MIBC.: Methods: A non-systematic literature search in Medline/Pubmed was performed in October 2023 with the following ... ...

    Abstract Objective: The aim of this review is to summarize the current evidence and future perspectives of bladder-sparing treatment for MIBC.
    Methods: A non-systematic literature search in Medline/Pubmed was performed in October 2023 with the following keywords "bladder cancer", "bladder-sparing", "trimodal therapy", "chemoradiation", "biomarkers", "immunotherapy", "neoadjuvant chemotherapy", "radiotherapy".
    Results: Urology guidelines recommend radical cystectomy as the standard curative treatment for muscle-invasive urothelial bladder cancer, reserving radiotherapy for patients who are unfit or who want to preserve their bladder. Given the morbidity and mortality of cystectomy and its impact on quality of life and bladder function, modern oncologic therapies are increasingly oriented toward organ preservation and maximizing functional outcomes while maintaining treatment efficacy. Trimodal therapy, which incorporates maximal transurethral resection followed by radiotherapy with concurrent radiosensitizing chemotherapy, is an effective regimen for bladder function preservation in well-selected patients. Despite the absence of comparative data from randomized trials, the two approaches seem to provide comparable oncologic outcomes. Studies are evaluating the expansion of eligibility criteria for trimodal therapy, the optimization of radiotherapy and immunotherapy delivery to further improve outcomes, and the validation of biomarkers to guide bladder preservation.
    Conclusions: Trimodal therapy has shown acceptable outcomes for bladder preservation; therefore, it provides a valid treatment option in well-selected patients.
    Language Spanish
    Publishing date 2024-04-02
    Publishing country Spain
    Document type Journal Article ; Review
    ISSN 2173-5786
    ISSN (online) 2173-5786
    DOI 10.1016/j.acuroe.2024.04.001
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: New strategies for decision making in prostate cancer. The role of oncotypedx.

    Toribio-Vázquez, C / Gómez Rivas, J / Yebes, Á / Carrión, D M / Yagüe Barrado, M / Álvarez-Maestro, M / Martinez-Piñeiro, L

    Actas urologicas espanolas

    2022  Volume 46, Issue 7, Page(s) 385–386

    MeSH term(s) Decision Making ; Humans ; Male ; Prognosis ; Prostatic Neoplasms/genetics ; Prostatic Neoplasms/therapy
    Language Spanish
    Publishing date 2022-07-13
    Publishing country Spain
    Document type Editorial
    ISSN 2173-5786
    ISSN (online) 2173-5786
    DOI 10.1016/j.acuroe.2022.01.005
    Database MEDical Literature Analysis and Retrieval System OnLINE

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