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  1. Article ; Online: SpNetPrep

    Álvaro Briz-Redón

    Research Ideas and Outcomes, Vol 5, Iss , Pp 1-

    An R package using Shiny to facilitate spatial statistics on road networks

    2019  Volume 17

    Abstract: Spatial statistics is an important field of data science with many applications in very different areas of study such as epidemiology, criminology, seismology, astronomy and econometrics, among others. In particular, spatial statistics has frequently ... ...

    Abstract Spatial statistics is an important field of data science with many applications in very different areas of study such as epidemiology, criminology, seismology, astronomy and econometrics, among others. In particular, spatial statistics has frequently been used to analyze traffic accidents datasets with explanatory and preventive objectives. Traditionally, these studies have employed spatial statistics techniques at some level of areal aggregation, usually related to administrative units. However, last decade has brought an increasing number of works on the spatial incidence and distribution of traffic accidents at the road level by means of the spatial structure known as a linear network. This change seems positive because it could provide deeper and more accurate investigations than previous studies that were based on areal spatial units. The interest in working at the road level renders some technical difficulties due to the high complexity of these structures, specially in terms of manipulation and rectification. The R Shiny app SpNetPrep, which is available online and via an R package named the same way, has the goal of providing certain functionalities that could be useful for a user which is interested in performing an spatial analysis over a road network structure.
    Keywords R package ; spatial statistics ; linear networks ; Science ; Q
    Language English
    Publishing date 2019-02-01T00:00:00Z
    Publisher Pensoft Publishers
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: Novel pedagogical tool for simultaneous learning of plane geometry and R programming

    Álvaro Briz-Redón / Ángel Serrano-Aroca

    Research Ideas and Outcomes, Vol 4, Iss , Pp 1-

    2018  Volume 24

    Abstract: Programming a computer is an activity that can be very beneficial to undergraduate students in terms of improving their mental capabilities, collaborative attitudes and levels of engagement in learning. Despite the initial difficulties that typically ... ...

    Abstract Programming a computer is an activity that can be very beneficial to undergraduate students in terms of improving their mental capabilities, collaborative attitudes and levels of engagement in learning. Despite the initial difficulties that typically arise when learning to program, there are several well-known strategies to overcome them, providing a very high benefit-cost ratio to most of the students. Moreover, the use of a programming language usually raises the interest of students to learn any specific concept, which has caused that many teachers around the world employ a programming language as a learning environment to treat almost every possible topic. Particularly, mathematics can be taught and learnt while using a suitable programming language. The R programming language is endowed with a wide range of capabilities that allow its use to learn different kind of concepts while programming. Therefore, complex subjects such as mathematics could be learnt with the help of this powerful programming language. In addition, since the R language provides numerous graphical functions, it could be very useful to acquire simultaneously basic plane geometry and programming knowledge at the undergraduate level. This paper describes the LearnGeom R package, a novel pedagogical tool, which contains multiple functions to learn geometry in R at different levels of difficulty, from the most basic geometric objects to high-complexity geometric constructions, while developing numerous programming skills.
    Keywords Science ; Q
    Subject code 000
    Language English
    Publishing date 2018-04-01T00:00:00Z
    Publisher Pensoft Publishers
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: Saccharomyces Cerevisiae Var. Boulardii

    Joaquín Mulero-Cerezo / Álvaro Briz-Redón / Ángel Serrano-Aroca

    Applied Sciences, Vol 9, Iss 16, p

    Valuable Probiotic Starter for Craft Beer Production

    2019  Volume 3250

    Abstract: The use of probiotic starters remaining viable in unpasteurized and unfiltered beers could significantly increase health benefits. Here, the probiotic Saccharomyces cerevisiae var. boulardii ( Sc b ) and a commercial Saccharomyces cerevisiae ( Sc ) ... ...

    Abstract The use of probiotic starters remaining viable in unpasteurized and unfiltered beers could significantly increase health benefits. Here, the probiotic Saccharomyces cerevisiae var. boulardii ( Sc b ) and a commercial Saccharomyces cerevisiae ( Sc ) strain, which is commonly employed in the brewing industry, are compared as single starters. The healthy value of the produced beers and growth performance in a laboratory bioreactor are analysed by determining antioxidant activity, phenolic content and profile, alcohol, biomass growth modelling by the logistic and Gompertz equations, biovolume estimation from 2D microscopy images, and yeast viability after fermentation. Thus, in this study, the craft beer produced with the probiotic yeast possessed higher antioxidant activity, lower alcohol content, similar sensory attributes, much higher yeast viability and more acidification, which is very desirable to reduce contamination risks at large-scale production. Furthermore, Sc b exhibited faster growth in the bioreactor culture and larger cell volumes than Sc , which increases the probiotic volume of the final craft beer.
    Keywords craft beer ; Saccharomyces cerevisiae var. boulardii ; Saccharomyces cerevisiae ; antioxidant activity ; polyphenols ; biovolume ; yeast viability ; probiotics ; bioreactor ; Logistic and Gompertz equations ; Technology ; T ; Engineering (General). Civil engineering (General) ; TA1-2040 ; Biology (General) ; QH301-705.5 ; Physics ; QC1-999 ; Chemistry ; QD1-999
    Language English
    Publishing date 2019-08-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article ; Online: Noise Disturbances and Calls for Police Service in València (Spain)

    Lia Seguí / Adina Iftimi / Álvaro Briz-Redón / Lucía Martínez-Garay / Francisco Montes

    International Journal of Environmental Research and Public Health, Vol 16, Iss 16, p

    A Logistic Model with Spatial and Temporal Effects

    2019  Volume 2815

    Abstract: The purpose of this paper is to explore the presence of spatial and temporal effects on the calls for noise disturbance service reported to the Local Police of València (Spain) in the time period from 2014 to 2015, and investigate how some socio- ... ...

    Abstract The purpose of this paper is to explore the presence of spatial and temporal effects on the calls for noise disturbance service reported to the Local Police of València (Spain) in the time period from 2014 to 2015, and investigate how some socio-demographic and environmental variables affect the noise phenomenon. The analysis is performed at the level of València’s boroughs. It has been carried out using a logistic model after dichotomization of the noise incidence variable. The spatial effects consider first- and second-order neighbors. The temporal effects are included in the model by means of one- and two-week temporal lags. Our model confirms the presence of strong spatio-temporal effects. We also find significant associations between noise incidence and specific age groups, socio-economic status, land uses, and recreational activities, among other variables. The results suggest that there is a problem of "social" noise in València that is not exclusively a consequence of coexistence between local residents. External factors such as the increasing number of people on the streets during weekend nights or during summer months severely increase the chances of expecting a noise incident.
    Keywords noise disturbances ; resident complaints ; logistic regression ; spatio-temporal effects ; socio-demographic and environmental effects ; GIS ; Medicine ; R
    Language English
    Publishing date 2019-08-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article ; Online: Injectable Gel Form of a Decellularized Bladder Induces Adipose-Derived Stem Cell Differentiation into Smooth Muscle Cells In Vitro

    Victoria Moreno-Manzano / Daria Zaytseva-Zotova / Eric López-Mocholí / Álvaro Briz-Redón / Berit Løkensgard Strand / Ángel Serrano-Aroca

    International Journal of Molecular Sciences, Vol 21, Iss 8608, p

    2020  Volume 8608

    Abstract: Biologic scaffolds composed of extracellular matrix components have been proposed to repair and reconstruct a variety of tissues in clinical and pre-clinical studies. Injectable gels can fill and conform any three-dimensional shape and can be delivered ... ...

    Abstract Biologic scaffolds composed of extracellular matrix components have been proposed to repair and reconstruct a variety of tissues in clinical and pre-clinical studies. Injectable gels can fill and conform any three-dimensional shape and can be delivered to sites of interest by minimally invasive techniques. In this study, a biological gel was produced from a decellularized porcine urinary bladder by enzymatic digestion with pepsin. The enzymatic digestion was confirmed by visual inspection after dissolution in phosphate-buffered saline solution and Fourier-transform infrared spectroscopy. The rheological and biological properties of the gel were characterized and compared to those of the Matrigel TM chosen as a reference material. The storage modulus G’ reached 19.4 ± 3.7 Pa for the 30 mg/mL digested decellularized bladder gels after ca. 3 h at 37 °C. The results show that the gel formed of the porcine urinary bladder favored the spontaneous differentiation of human and rabbit adipose-derived stem cells in vitro into smooth muscle cells to the detriment of cell proliferation. The results support the potential of the developed injectable gel for tissue engineering applications to reconstruct for instance the detrusor muscle part of the human urinary bladder.
    Keywords gel ; extracellular matrix ; viscoelasticity ; rheology ; scaffold ; pepsin ; Biology (General) ; QH301-705.5 ; Chemistry ; QD1-999
    Subject code 610
    Language English
    Publishing date 2020-11-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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    Inter-library loan at ZB MED

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