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  1. Article: Multidetector Computed Tomographic Evaluation of the Normal Characteristics of the Thymus in the Pediatric Population.

    Çolak, Edis / Özkan, Behzat

    Journal of the Belgian Society of Radiology

    2022  Volume 106, Issue 1, Page(s) 110

    Abstract: Objectives: The objective of the present study was to determine the morphologic features and measurements of the normal thymus on contrast-enhanced multi-detector computed tomography (MDCT) in subjects from the newborn period up to 18 years of age.: ... ...

    Abstract Objectives: The objective of the present study was to determine the morphologic features and measurements of the normal thymus on contrast-enhanced multi-detector computed tomography (MDCT) in subjects from the newborn period up to 18 years of age.
    Materials and methods: The MDCT scans obtained from 464 children with a mean age ± SD of 8.43 ± 5.60 years were retrospectively re-evaluated. The shape, margins, side predominance, density, and measurements of the thymic gland were defined for each age group.
    Results: A triangular thymic shape with a middle location and straight lateral contours were the most frequently seen morphologic features in children. The mean anteroposterior and transverse diameter of the thymus was 17.32 ± 4.58 and 29.99 ± 11.42 mm, respectively. The mean values for the width and thickness were 20.66 ± 5.36 and 15.15 ± 6.76 mm for the right thymic lobe, respectively; and 26.14 ± 7.85 and 14.91 ± 5.51 mm for the left, respectively. The transverse diameter of the thymus and thymic lobe dimensions decreased significantly with age, however, the anteroposterior diameter of the thymus was not significantly associated with age. Girls had higher mean thymic attenuation values compared to boys, however, this gender difference was not statistically significant (63.8 ± 22.4 HU vs. 60.1 ± 25.3, p = 0.164).
    Conclusion: Our study provides a better understanding of the normal thymic appearances in children that can aid in accurate diagnosis and avoid unnecessary, costly, and invasive interventions.
    Language English
    Publishing date 2022-11-17
    Publishing country England
    Document type Journal Article
    ZDB-ID 2834839-4
    ISSN 2514-8281
    ISSN 2514-8281
    DOI 10.5334/jbsr.2971
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Ultrasonographic measurements of the testicular volume in Turkish boys aged 0-8 years and comparison with international references.

    Çolak, Edis / Özkan, Behzat

    Journal of pediatric endocrinology & metabolism : JPEM

    2022  Volume 35, Issue 4, Page(s) 489–495

    Abstract: Objectives: Proper diagnosis and follow-up of children with testicular disorders depend on the presence of adequate references for testicular volume. The objective of this study was to determine the testicular volume by ultrasound in Turkish boys aged ... ...

    Abstract Objectives: Proper diagnosis and follow-up of children with testicular disorders depend on the presence of adequate references for testicular volume. The objective of this study was to determine the testicular volume by ultrasound in Turkish boys aged between 0 and 8 years.
    Methods: A total of 320 boys with bilaterally descended testes underwent scrotal ultrasound examinations. The testicular volume (mL) was calculated by the empirical formula of Lambert (V=L × T × AP × 0.71) and the formula for an ellipsoid (V=L × T × AP × 
    Results: The median (IQR) volume of the right and left testis were 0.75 (0.57-0.99) and 0.72 (0.56-0.98) mL (formula of Lambert), respectively; and 0.56 (0.42-0.73) and 0.53 (0.41-0.72) mL, (formula for an ellipsoid), respectively. The age-specific median of the average volume of the right and left testis estimated by the Lambert equation in the first five years was measured between 0.63 and 0.71 mL, followed by an increase to about 1.31 mL at the age of 8. This increase was highly statistically significant (p<0.0001). No significant association was found between the Z-scores for weight, height, and BMI of boys and the testicular volumes.
    Conclusions: This study provides the first national ultrasound-based estimates for testicular volume in Turkish boys aged 0-8 years.
    MeSH term(s) Body Height ; Child ; Child, Preschool ; Humans ; Infant ; Infant, Newborn ; Male ; Organ Size ; Testicular Diseases ; Testis/diagnostic imaging ; Ultrasonography
    Language English
    Publishing date 2022-02-17
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1231070-0
    ISSN 2191-0251 ; 0334-018X
    ISSN (online) 2191-0251
    ISSN 0334-018X
    DOI 10.1515/jpem-2021-0635
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2258: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  3. Article ; Online: Sonographic evaluation of normal thyroid volume and thyroid isthmus depth among infants in the west coast of Turkey.

    Çolak, Edis / Özkan, Behzat

    Endokrynologia Polska

    2022  Volume 73, Issue 2, Page(s) 325–329

    Abstract: Introduction: The reference values for thyroid volume (TV) suggested by the WHO are recommended for children aged 6 to 12 years and cannot be considered relevant for infants. The present study aimed to establish the normal values for TV and thyroid ... ...

    Abstract Introduction: The reference values for thyroid volume (TV) suggested by the WHO are recommended for children aged 6 to 12 years and cannot be considered relevant for infants. The present study aimed to establish the normal values for TV and thyroid isthmus depth (TID) in infants aged between 1 and 12 months from the west coast of Turkey.
    Material and methods: The TV and TID were measured in 223 infants by a validated ultrasound technique. The TV was determined by the method of Brunn et al. and Brown et al. The 3rd, 25th, 50th, 75th, and 97th percentiles of the TV and TID according to age were produced. The TV and TID measurements were compared with infants' age, gender, and standard deviation (Z) scores for weight, height, and BMI.
    Results: The median (IQR) values for TV were 0.77 (0.61-1.00) and 0.84 (0.67-1.10) mL, calculated according to the formula of Brunn et al. and Brown et al., respectively. The TV was significantly associated with age, and Z scores for weight, height, and body mass index (BMI) (r = 0.366, p < 0.001; r = 0.343, p < 0.0001; r = 0.269, p < 0.0001; and r = 0.157, p = 0.019; respectively). The median (IQR) value for the TID was 1.5 (1.3-1.9) mm. The TID was significantly correlated with TV and the Z score for height (r = 0.190, p = 0.004; and r = 0.144, p = 0.032; respectively). In multivariable regression, the only independent predictor for TV was the Z score for BMI. No differences based on gender were found.
    Conclusions: This is the first study to report the normative values for TV and TID in healthy Turkish infants aged up to 12 months. Our findings may serve as a basis for developing national and international references for TV and TID in infants.
    MeSH term(s) Body Height ; Body Mass Index ; Body Weight ; Child ; Humans ; Infant ; Reference Values ; Thyroid Gland/diagnostic imaging ; Turkey ; Ultrasonography
    Language English
    Publishing date 2022-04-05
    Publishing country Poland
    Document type Journal Article
    ZDB-ID 419270-9
    ISSN 2299-8306 ; 0423-104X
    ISSN (online) 2299-8306
    ISSN 0423-104X
    DOI 10.5603/EP.a2022.0012
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 204: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  4. Article ; Online: Ultrasonographic determination of thyroid volume in infants and children from Aegean region of Turkey and comparison with national and international references.

    Çolak, Edis / Özkan, Behzat / Genç, Sinan / Polat, Burak

    Journal of pediatric endocrinology & metabolism : JPEM

    2021  Volume 34, Issue 4, Page(s) 457–464

    Abstract: Objectives: Accurate diagnosis and follow-up of pediatric patients with thyroid disorders, depends on the availability of appropriate data for normal thyroid volume (TV). The aim of this study was to determine the TV by ultrasonography (US) in subjects ... ...

    Abstract Objectives: Accurate diagnosis and follow-up of pediatric patients with thyroid disorders, depends on the availability of appropriate data for normal thyroid volume (TV). The aim of this study was to determine the TV by ultrasonography (US) in subjects from the newborn period up to 18 years of age from the Aegean region of Turkey.
    Methods: We measured the thyroid volumes in 513 children using US and compared them with the children's age, gender, standard deviation score (SDS) of body height (BH-SDS), body weight (BW-SDS), body mass index (BMI-SDS), and body surface area (BSA-SDS). The 3rd, 50th, and 97th percentiles of the age-dependent distribution of the TV were calculated and compared with national and international references.
    Results: The BH, BW, BMI, and BSA of all the participants were within the normal ranges for Turkish children. The TV was significantly positively correlated with age, gender, BH-SDS, BW-SDS, BMI-SDS, and BSA-SDS in all subjects (r=0.748, r=0.267, r=0.730, r=0.735, r=0.664 and r=0.735, respectively; p<0.0001 for all). The most important predictors for TV were age and BW-SDS, followed by BSA-SDS and BH-SDS. In multivariate regression, age and BW-SDS were the only significant independent predictors for TV. Our results were nearly similar to the corresponding data reported by the World Health Organisation in 2004.
    Conclusions: The present study provides updated values for TV that can serve as a potential tool in differentiating the normal from the abnormal size of the thyroid gland in children aged 0-18 years from the Aegean region of Turkey.
    MeSH term(s) Adolescent ; Aging ; Body Height ; Body Mass Index ; Body Surface Area ; Body Weight ; Child ; Child, Preschool ; Female ; Humans ; Infant ; Male ; Reference Standards ; Retrospective Studies ; Sex Characteristics ; Thyroid Diseases ; Thyroid Gland/diagnostic imaging ; Turkey ; Ultrasonography
    Language English
    Publishing date 2021-02-24
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1231070-0
    ISSN 2191-0251 ; 0334-018X
    ISSN (online) 2191-0251
    ISSN 0334-018X
    DOI 10.1515/jpem-2020-0514
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2258: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

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