LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 22

Search options

  1. Article ; Online: Solar retinopathy from sun gazing under the influence of ecstasy: A longitudinal analysis of OCT and OCTA findings.

    Demirtaş, Atılım Armağan / Öncül, Hasan

    Photodiagnosis and photodynamic therapy

    2021  Volume 35, Page(s) 102359

    Abstract: This report presents the clinical and optical coherence tomography (OCT) and OCT angiography (OCTA) findings from a case of acute and chronic solar retinopathy (SR) caused by sun gazing while under the influence of the hallucinogenic drug ... ...

    Abstract This report presents the clinical and optical coherence tomography (OCT) and OCT angiography (OCTA) findings from a case of acute and chronic solar retinopathy (SR) caused by sun gazing while under the influence of the hallucinogenic drug methylenedioxymethamphetamine, which is commonly known as ecstasy. This retrospective and observational case report involves a 16-year-old male patient who developed disruption of all foveolar layers two days after using ecstasy and subsequently gazing at the sun. The patient underwent visual acuity testing, dilated fundus examination, visual field analysis, OCT, and OCTA imaging. He exhibited visual recovery with the permanent disruption of the photoreceptor outer layers, and demonstrated enlargement in the deep foveal avascular zone areas during later follow-up periods, from one month to two years. This report aims to draw attention to SR that may occur after sun gazing while using hallucinogenic drugs and the importance of OCT and OCTA imaging in follow-up exams in such cases.
    MeSH term(s) Adolescent ; Fluorescein Angiography ; Humans ; Male ; N-Methyl-3,4-methylenedioxyamphetamine ; Photochemotherapy/methods ; Photosensitizing Agents ; Retinal Diseases ; Retrospective Studies ; Sunlight ; Tomography, Optical Coherence
    Chemical Substances Photosensitizing Agents ; N-Methyl-3,4-methylenedioxyamphetamine (KE1SEN21RM)
    Language English
    Publishing date 2021-05-25
    Publishing country Netherlands
    Document type Case Reports ; Journal Article ; Observational Study
    ZDB-ID 2149918-4
    ISSN 1873-1597 ; 1572-1000
    ISSN (online) 1873-1597
    ISSN 1572-1000
    DOI 10.1016/j.pdpdt.2021.102359
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  2. Article ; Online: Evaluation of corneal densitometry changes in patients with lichen planus.

    Öncül, Hasan / Ayhan, Erhan

    International journal of clinical practice

    2021  Volume 75, Issue 7, Page(s) e14234

    Abstract: Purpose: To investigate the corneal topography and densitometry changes in patients with lichen planus (LP).: Methods: Anterior segment parameters and corneal densitometry of patients with LP and age- and gender-matched individuals with healthy eyes ... ...

    Abstract Purpose: To investigate the corneal topography and densitometry changes in patients with lichen planus (LP).
    Methods: Anterior segment parameters and corneal densitometry of patients with LP and age- and gender-matched individuals with healthy eyes were evaluated using Scheimpflug corneal topography. A 12 mm corneal area was divided into 4 annular zones and 3 regions-in-depth anterior, central and posterior-for densitometry evaluation.
    Results: The study included 45 patients with LP and 50 individuals with healthy eyes. The two groups were similar in age and gender, and they showed no significant differences in anterior segment corneal topography parameters. Schirmer's I test results were significantly lower in the patients with LP than in the control group (P ˂ .001). The total corneal densitometry was higher in patients with LP than in the control group (P = .030). The anterior, central and posterior corneal densitometry in the 0-2 mm and 2-6 mm annular zones was higher in the LP group than in the control group. Correlation analysis between disease duration and corneal densitometry values showed a strong positive correlation in the anterior segment and a moderate positive correlation in the central and posterior segments (r = 0.632, P ˂ .001; r = 0.572, P ˂ .001; and r = 0.562, P ˂ .001, respectively).
    Conclusions: Corneal densitometry values were higher in patients with LP than in individuals with healthy eyes, even if the patients had a clinically transparent cornea. More studies are needed to evaluate the changes that may occur in corneal transparency in patients with LP and other autoimmune dermatologic diseases that may affect the eye.
    Language English
    Publishing date 2021-04-27
    Publishing country England
    Document type Journal Article
    ZDB-ID 1386246-7
    ISSN 1742-1241 ; 1368-5031
    ISSN (online) 1742-1241
    ISSN 1368-5031
    DOI 10.1111/ijcp.14234
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  3. Article ; Online: A rare complication of combined oral contraceptives (COCs): optic neuritis.

    Ege, Serhat / Öncül, Hasan

    Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology

    2020  Volume 41, Issue 2, Page(s) 319–320

    MeSH term(s) Androstenes/adverse effects ; Contraceptives, Oral, Combined/adverse effects ; Ethinyl Estradiol/adverse effects ; Female ; Humans ; Optic Neuritis/chemically induced ; Young Adult
    Chemical Substances Androstenes ; Contraceptives, Oral, Combined ; drospirenone and ethinyl estradiol combination ; Ethinyl Estradiol (423D2T571U)
    Language English
    Publishing date 2020-02-08
    Publishing country England
    Document type Case Reports ; Journal Article
    ZDB-ID 604639-3
    ISSN 1364-6893 ; 0144-3615
    ISSN (online) 1364-6893
    ISSN 0144-3615
    DOI 10.1080/01443615.2019.1706462
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  4. Article ; Online: Successful Treatment of Conjunctival Kaposi Sarcoma in a Human Immunodeficiency Virus-Negative Kidney Transplant Recipient: A Case Report.

    Gunay, Emrah / Oncul, Hasan

    Transplantation proceedings

    2020  Volume 52, Issue 2, Page(s) 622–624

    Abstract: Kaposi sarcoma (KS) is the most common tumor in patients with human immunodeficiency virus (HIV), and its frequency is increasing after organ transplantation in HIV-negative patients. A 28-year-old woman had preemptive kidney transplantation from her 48- ... ...

    Abstract Kaposi sarcoma (KS) is the most common tumor in patients with human immunodeficiency virus (HIV), and its frequency is increasing after organ transplantation in HIV-negative patients. A 28-year-old woman had preemptive kidney transplantation from her 48-year-old mother. In the postoperative ninth month, an exophytic mass was found in the upper medial conjunctiva of the right eye. The lesion was excised under local anesthesia, and cryotherapy was applied to the surgical area. The biopsy result was reported as KS. Treatment with tacrolimus was switched to everolimus (EVO), but EVO was discontinued because of pneumonitis. The patient was followed without any recurrences after the excision of the conjunctival lesion. No local or systemic recurrence was observed in the 14th month after surgical excision and local cryotherapy. Local treatment and the reduction of immunosuppressive therapy may be effective in the treatment of conjunctival KS.
    MeSH term(s) Adult ; Conjunctival Neoplasms/immunology ; Conjunctival Neoplasms/surgery ; Everolimus/therapeutic use ; Female ; HIV Infections/complications ; Humans ; Immunocompromised Host ; Immunosuppression/adverse effects ; Immunosuppression/methods ; Immunosuppressive Agents/therapeutic use ; Kidney Transplantation ; Sarcoma, Kaposi/immunology ; Sarcoma, Kaposi/surgery ; Tacrolimus/therapeutic use
    Chemical Substances Immunosuppressive Agents ; Everolimus (9HW64Q8G6G) ; Tacrolimus (WM0HAQ4WNM)
    Language English
    Publishing date 2020-02-06
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 82046-5
    ISSN 1873-2623 ; 0041-1345
    ISSN (online) 1873-2623
    ISSN 0041-1345
    DOI 10.1016/j.transproceed.2019.12.005
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  5. Article ; Online: Retinal nerve fiber layer, retinal pigment epithelium, and choroidal thickness in vitiligo patients.

    Öncül, Hasan / Ayhan, Erhan

    Journal of cosmetic dermatology

    2020  Volume 19, Issue 11, Page(s) 3032–3037

    Abstract: Background: Vitiligo is one of the common pigmentary disorders affecting the ocular structures.: Aim: To determine the retinal nerve fiber layer (RNFL), retinal pigment epithelium (RPE), and choroidal thickness (CT) in vitiligo patients and to ... ...

    Abstract Background: Vitiligo is one of the common pigmentary disorders affecting the ocular structures.
    Aim: To determine the retinal nerve fiber layer (RNFL), retinal pigment epithelium (RPE), and choroidal thickness (CT) in vitiligo patients and to evaluate the relationship between choroidal thickness and vitiligo subtypes.
    Methods: The right eyes of 106 participants (51 vitiligo, 55 nonvitiligo) were included in the study. All of the participants underwent detailed eye examinations and spectral-domain optical coherence tomography (SD-OCT) examinations. CT was measured manually with enhanced depth imaging optical coherence tomography (Edi-OCT) (subfoveal [SubF], nasal n500 µm [N1], n1500 µm [N2]), and temporal (t500 µm [T1], t1500 µm [T2]).
    Results: In vitiligo patients, CT values were significantly lower in the SubF, N1, N2, T1, and T2 areas compared to the control group (P = .001, P = .011, P = .002, P = .005, P ˂ .001, respectively). Periorbital involvement did not affect CT (P = .355, P = .746, P = .443, P = .633, P = .558, respectively). However, in patients with periorbital region involvement, the CT was significantly reduced if the lesion had a universal character (P ˂ .001, P = .001, P = .011, P ˂ .001, P = .002, respectively). It was observed that RPE thickness decreased in vitiligo, but this difference was not statistically significant (P = .140). RNFL thickness was unaffected in all quadrants. A positive correlation (r = .286, r = .280, respectively) was observed between the Vitiligo Area Severity Index (VASI) and age and disease duration. A negative correlation (r = -.360, r = -.316, r = -.315, r = -.313, respectively) was found in the CT of the SubF, N1, N2, T1, and T2 areas.
    Conclusion: Vitiligo patients should be closely monitored for possible posterior ocular segment disorders.
    MeSH term(s) Choroid/diagnostic imaging ; Humans ; Nerve Fibers ; Retinal Pigment Epithelium/diagnostic imaging ; Tomography, Optical Coherence ; Vitiligo/diagnostic imaging
    Language English
    Publishing date 2020-06-09
    Publishing country England
    Document type Journal Article
    ZDB-ID 2280551-5
    ISSN 1473-2165 ; 1473-2130
    ISSN (online) 1473-2165
    ISSN 1473-2130
    DOI 10.1111/jocd.13367
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  6. Article ; Online: Evaluation of Infectious Uveitis at a Tertiary Referral Center in Turkey: A 31-year Retrospective Study.

    Oncul, Hasan / Kara, Caner / Ozdal, Pinar Cakar

    Beyoglu eye journal

    2021  Volume 6, Issue 2, Page(s) 115–123

    Abstract: Objectives: The aim of this study was to examine the demographic and clinical characteristics of patients with infectious uveitis over time.: Methods: The records of a total of 2032 patients treated for uveitis were retrospectively analyzed and 369 ... ...

    Abstract Objectives: The aim of this study was to examine the demographic and clinical characteristics of patients with infectious uveitis over time.
    Methods: The records of a total of 2032 patients treated for uveitis were retrospectively analyzed and 369 eyes of 324 patients diagnosed with infectious uveitis were included in the study. The patients were divided into 2 groups according to the date of presentation. The first group comprised patients seen between January 1988 and August 2009, and patients who presented between September 2009 and April 2019 were classified in the second group.
    Results: The prevalence of infectious uveitis was 15.1% in the first group and 16.8% in the second group. A statistically significant decrease was observed in the number of toxoplasmosis patients in the second group (p=0.031). There was no significant difference in the number of patients with herpetic anterior uveitis (HAU) (p=0.215). A significant increase was recorded in the number of patients with tuberculosis and acute retinal necrosis (ARN) (p=0.006 and p=0.041, respectively). While there were no patients diagnosed with cytomegalovirus (CMV) anterior uveitis in the first group, 19 patients were diagnosed with the disorder in the second group. There was a decrease in the rate of legal blindness among the patients who were treated in the second period compared with the first period; however, this difference was not statistically significant (p=0.069).
    Conclusion: Toxoplasmosis and HAU were the 2 most common causes of infectious uveitis. The incidence of CMV anterior uveitis, tuberculosis-related uveitis, and ARN increased over the period studied.
    Language English
    Publishing date 2021-06-08
    Publishing country Turkey
    Document type Journal Article
    ZDB-ID 3031466-5
    ISSN 2587-0394 ; 2459-1777
    ISSN (online) 2587-0394
    ISSN 2459-1777
    DOI 10.14744/bej.2021.48726
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  7. Article ; Online: The relationship between reduced choroidal thickness due to high plasma asymmetrical dimethylarginine level and increased severity of diabetic retinopathy.

    Dag, Umut / Çaglayan, Mehtap / Alakus, Mehmet Fuat / Öncül, Hasan

    Arquivos brasileiros de oftalmologia

    2022  Volume 86, Issue 1, Page(s) 27–32

    Abstract: Purpose: To evaluate the relationship between subfoveal choroidal thickness and plasma asymmetrical dimethylarginine level and the severity of diabetic retinopathy in patients with type 2 diabetes mellitus.: Methods: A total of 68 cases, including 15 ...

    Abstract Purpose: To evaluate the relationship between subfoveal choroidal thickness and plasma asymmetrical dimethylarginine level and the severity of diabetic retinopathy in patients with type 2 diabetes mellitus.
    Methods: A total of 68 cases, including 15 patients without diabetic retinopathy, 17 patients with nonproliferative diabetic retinopathy, 16 patients with type 2 diabetes mellitus and proliferative diabetic retinopathy, and 20 healthy patients (control group), were enrolled in this study. Subfoveal choroidal thickness was measured manually using the enhanced depth imaging optical coherence tomography scanning program, and plasma asymmetrical dimethylarginine level was measured using a commercial micro enzyme-linked immunosorbent assay kit.
    Results: The subfoveal choroidal thickness values and plasma asymmetrical dimethylarginine levels were significantly different between the four groups (p<0.001 and p<0.001). The subfoveal choroidal thickness values were significantly lower in the proliferative diabetic retinopathy group than in the other three groups (no diabetic retinopathy, nonproliferative diabetic retinopathy, and control groups; p<0.001, p=0.045, and p<0.001, respectively). The plasma asymmetrical dimethylarginine levels were significantly higher in the proliferative diabetic retinopathy group than in the other three groups (p<0.001, p<0.04, and p<0.001, respectively). In addition, a significant negative correlation was also found between plasma asymmetrical dimethylarginine level and subfoveal choroidal thickness (p<0.001, r=-0.479).
    Conclusion: Asymmetrical dimethylarginine is an important marker of endothelial dysfunction and endogenous endothelial nitric oxide synthase inhibitor. The severity of diabetic retinopathy was related to increased plasma asymmetrical dimethylarginine level and reduced subfoveal choroidal thickness in type 2 diabetic patients with diabetic retinopathy.
    MeSH term(s) Humans ; Diabetes Mellitus, Type 2/complications ; Social Group
    Language English
    Publishing date 2022-02-16
    Publishing country Brazil
    Document type Journal Article
    ZDB-ID 603915-7
    ISSN 1678-2925 ; 0004-2749
    ISSN (online) 1678-2925
    ISSN 0004-2749
    DOI 10.5935/0004-2749.20230007
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  8. Article ; Online: Evaluation of changes in lens optical densitometry using Pentacam HR after renal transplantation: A prospective study.

    Öncül, Hasan / Günay, Emrah / Ay, Nurettin

    Photodiagnosis and photodynamic therapy

    2021  Volume 35, Page(s) 102423

    Abstract: Background: To compare the optical densitometric changes in the lens of patients with renal transplantation with those of a healthy group using Pentacam HR.: Methods: Twenty-four right eyes of 24 healthy patients (Group 1) were compared with 24 right ...

    Abstract Background: To compare the optical densitometric changes in the lens of patients with renal transplantation with those of a healthy group using Pentacam HR.
    Methods: Twenty-four right eyes of 24 healthy patients (Group 1) were compared with 24 right eyes of 24 kidney transplant recipients. Kidney transplant recipients were evaluated thrice (preoperatively: Group 2a, postoperative 1st month: Group 2b, postoperative 12th month: Group 2c). Corneal endothelial cell count, intraocular pressure, and central corneal thickness of all participants were measured. Lens optical densitometry was measured with Pentacam HR using 3D scanning mode. The optical density of the lens was analyzed by taking the corneal apex as the center and analysing the 12 mm diameter area. (Zone 1: 2.0 mm, Zone 2: 4.0 mm, and Zone 3: 6.0 mm).
    Results: Corneal endothelial cell count was 2571.2±106.7 cells/mm
    Conclusions: Although a decrease in lens transparency was observed after kidney transplantation, steroids may cause an increase in lens transparency in the postoperative period. Patients with renal transplantation should be followed closely for possible lens changes in the post-transplant period.
    MeSH term(s) Cornea ; Densitometry ; Humans ; Kidney Transplantation ; Photochemotherapy/methods ; Photosensitizing Agents ; Prospective Studies
    Chemical Substances Photosensitizing Agents
    Language English
    Publishing date 2021-06-29
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2149918-4
    ISSN 1873-1597 ; 1572-1000
    ISSN (online) 1873-1597
    ISSN 1572-1000
    DOI 10.1016/j.pdpdt.2021.102423
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  9. Article ; Online: Mask-associated Dry Eye Syndrome in Healthcare Professionals as a New Complication Caused by the Prolonged Use of Masks during Covid-19 Pandemic Period.

    Dag, Umut / Çaglayan, Mehtap / Öncül, Hasan / Vardar, Süleyman / Alaus, Mehmet Fuat

    Ophthalmic epidemiology

    2022  Volume 30, Issue 1, Page(s) 1–6

    Abstract: Purpose: The aim of this study is to demonstrate the prevalence of self-reported mask-associated dry eye (MADE) in health-care professionals and the possible risk factors that give rise to MADE.: Methods: A self-administered questionnaire consisting ... ...

    Abstract Purpose: The aim of this study is to demonstrate the prevalence of self-reported mask-associated dry eye (MADE) in health-care professionals and the possible risk factors that give rise to MADE.
    Methods: A self-administered questionnaire consisting of 12 questions about MADE and possible risk factors that give rise to MADE was created on web-based "google forms" application, and was then sent to 437 healthcare professionals working in a coronavirus-19 (COVID-19) pandemic hospital, using common telecommunication devices.
    Results: Three hundred and thirty-three of the 437 health-care professionals, who answered the questionnaire, were included in the study. The prevalence of self-reported MADE among these health-care professionals was found to be 70% (n = 233). Having at least one of the symptoms of dry eye while not having a mask on and advanced age were determined as the possible risk factors for MADE (
    Conclusion: The high prevalence of self-reported MADE among health-care professionals can be attributed to the prolonged use of masks associated with longer working hours. Therefore, it is important that the ocular complaints of professionals are addressed by ophthalmology consultants/ophthalmologists during these difficult times.
    MeSH term(s) Humans ; COVID-19/epidemiology ; Pandemics ; Masks ; Dry Eye Syndromes/diagnosis ; Dry Eye Syndromes/epidemiology ; Dry Eye Syndromes/etiology ; Delivery of Health Care
    Language English
    Publishing date 2022-03-18
    Publishing country England
    Document type Journal Article
    ZDB-ID 1213070-9
    ISSN 1744-5086 ; 0928-6586
    ISSN (online) 1744-5086
    ISSN 0928-6586
    DOI 10.1080/09286586.2022.2053549
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  10. Article ; Online: Central serous chorioretinopathy associated with high-dose follistatin-344: a retrospective case series.

    Dağ, Umut / Çağlayan, Mehtap / Öncül, Hasan / Alakuş, Mehmet Fuat

    International ophthalmology

    2020  Volume 40, Issue 11, Page(s) 3155–3161

    Abstract: Purpose: To present 11 bodybuilding athletes who developed central serous chorioretinopathy (CSCR) following high-dose subcutaneous follistatin-344, a peptide-based performance and image enhancing drug, injections to increase muscle mass.: Methods: ... ...

    Abstract Purpose: To present 11 bodybuilding athletes who developed central serous chorioretinopathy (CSCR) following high-dose subcutaneous follistatin-344, a peptide-based performance and image enhancing drug, injections to increase muscle mass.
    Methods: This is a retrospective case series from one institution. Demographic and clinical data of 11 patients who were admitted to our clinic with decreased visual acuity after high-dose follistatin-344 injections and optical coherence tomography (OCT) findings consistent with CSCR were analyzed.
    Results: All 11 patients were male, and the mean age was 36.8 ± 8.1 years. All patients had a history of injecting complete 1 mg vials of follistatin-344 subcutaneously in the abdomen. There was a history of a single previous high-dose follistatin-344 injection in eight patients and multiple previous injections in three patients. At the time of diagnosis, ten patients had unilateral CSCR findings and one had bilateral CSCR findings. In all eight patients with a history of only one injection, subretinal fluid completely disappeared after an average of 2.3 ± 0.7 months and symptoms regressed. Recurrent CSCR developed in three patients with a history of multiple follistatin-344 injections.
    Conclusion: Follistatin-344 injection can be considered as a risk factor for CSCR. To take medical history from CSCR patients including follistatin-344 use may be important to reveal the CSCR etiology.
    MeSH term(s) Adult ; Central Serous Chorioretinopathy/chemically induced ; Central Serous Chorioretinopathy/diagnosis ; Female ; Fluorescein Angiography ; Follistatin ; Humans ; Male ; Retrospective Studies ; Tomography, Optical Coherence ; Visual Acuity
    Chemical Substances Follistatin
    Language English
    Publishing date 2020-07-15
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 800087-6
    ISSN 1573-2630 ; 0165-5701
    ISSN (online) 1573-2630
    ISSN 0165-5701
    DOI 10.1007/s10792-020-01501-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

To top