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Article ; Online: Assessment of organizational carbon footprints in a denim-washing company: a systematic approach to indirect non-energy emissions.

Aykaç Özen, Hülya / Vayiç, Bahar / Çoruh, Semra

Environmental science and pollution research international

2024

Abstract: As stated in the 2016 Paris Agreement, concerns about global climate change and carbon emissions have increased, and organizations, in particular, have embarked on an annual measurement process to estimate their contribution to global climate change. ... ...

Abstract	As stated in the 2016 Paris Agreement, concerns about global climate change and carbon emissions have increased, and organizations, in particular, have embarked on an annual measurement process to estimate their contribution to global climate change. Carbon footprint, one of the measurement methods, is a widely applied tool to assess the environmental impact of organizations. This study presents a real case study of a denim-washing company's activities based on ISO standard calculation methods of greenhouse gas emissions. Accordingly, the annual carbon footprint of the denim-washing company was 2482.09 tCO
Language	English
Publishing date	2024-05-14
Publishing country	Germany
Document type	Journal Article
ZDB-ID	1178791-0
ISSN	1614-7499 ; 0944-1344
ISSN (online)	1614-7499
ISSN	0944-1344
DOI	10.1007/s11356-024-33640-z
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Article ; Online: Smoke filtration performances of membranes produced from commercial PVA and recycled PET by electrospinning method and ANN modeling

Özen, Hülya Aykaç / Mutuk, Tuğba / Yiğiter, Merve

Environ Sci Pollut Res. 2023 Jan., v. 30, no. 2 p.2469-2479

2023

Abstract: Plastic waste and air pollution are becoming a great concern due to their adverse effect on human health and the environment. There is increasing number of evidence showing that recycling plastic and filtering harmful air pollutants are one of the most ... ...

Abstract	Plastic waste and air pollution are becoming a great concern due to their adverse effect on human health and the environment. There is increasing number of evidence showing that recycling plastic and filtering harmful air pollutants are one of the most effective and promising way to eliminate their hazard on the environment. In this purpose, we developed eco-friendly filtration materials from recycled PET by electrospinning method to be used in air filtration and compared them with conventional PVA membranes. Filtration efficiency of prepared membranes were tested homemade membrane system using cigarette smoke source. Characterization results and smoke filtration performance of recycled PET and PVA membranes before and after smoke filtration were examined. The results demonstrated that the removal efficiencies of PVA-5 wt.%, PVA-10 wt.%, and PVA-15 wt.% were 4.11%, 11.32%, and 12.14%, respectively. A similar trend was also observed in recycled PET-5 wt.%, PET-10 wt.%, and PET-15 wt.% membranes with 4.32%, 10.79%, and 11.68% of filtration efficiency, respectively. Based on this result, using recycled PET can be an alternative way to produce a higher value product compared to traditional polymer membranes used commercially. This result is also supported by the neural network model of this study.
Keywords	adverse effects ; air ; air pollution ; cigarettes ; filtration ; human health ; neural networks ; polymers ; smoke ; wastes
Language	English
Dates of publication	2023-01
Size	p. 2469-2479.
Publishing place	Springer Berlin Heidelberg
Document type	Article ; Online
ZDB-ID	1178791-0
ISSN	1614-7499 ; 0944-1344
ISSN (online)	1614-7499
ISSN	0944-1344
DOI	10.1007/s11356-022-22383-4
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Article ; Online: Evaluation of the Effect of Self-Efficacy on Symptoms in Gastrointestinal Cancer Patients.

Ozkaraman, Ayşe / Kazak, Aysun / Dudaklı, Nuran / Ozen, Hülya

Journal of palliative care

2022 Volume 38, Issue 2, Page(s) 207–214

Abstract: Objective: ...

Abstract	Objective:
MeSH term(s)	Humans ; Adolescent ; Adult ; Middle Aged ; Aged ; Cross-Sectional Studies ; Self Efficacy ; Syndrome ; Neoplasms ; Pain ; Gastrointestinal Neoplasms/complications ; Nausea ; Fatigue/etiology ; Fatigue/epidemiology ; Sleep Wake Disorders/diagnosis ; Sleep Wake Disorders/epidemiology ; Xerostomia
Language	English
Publishing date	2022-09-21
Publishing country	United States
Document type	Journal Article
ZDB-ID	639326-3
ISSN	2369-5293 ; 0825-8597
ISSN (online)	2369-5293
ISSN	0825-8597
DOI	10.1177/08258597221125286
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Article ; Online: Smoke filtration performances of membranes produced from commercial PVA and recycled PET by electrospinning method and ANN modeling.

Özen, Hülya Aykaç / Mutuk, Tuğba / Yiğiter, Merve

Environmental science and pollution research international

2022 Volume 30, Issue 2, Page(s) 2469–2479

Abstract	Plastic waste and air pollution are becoming a great concern due to their adverse effect on human health and the environment. There is increasing number of evidence showing that recycling plastic and filtering harmful air pollutants are one of the most effective and promising way to eliminate their hazard on the environment. In this purpose, we developed eco-friendly filtration materials from recycled PET by electrospinning method to be used in air filtration and compared them with conventional PVA membranes. Filtration efficiency of prepared membranes were tested homemade membrane system using cigarette smoke source. Characterization results and smoke filtration performance of recycled PET and PVA membranes before and after smoke filtration were examined. The results demonstrated that the removal efficiencies of PVA-5 wt.%, PVA-10 wt.%, and PVA-15 wt.% were 4.11%, 11.32%, and 12.14%, respectively. A similar trend was also observed in recycled PET-5 wt.%, PET-10 wt.%, and PET-15 wt.% membranes with 4.32%, 10.79%, and 11.68% of filtration efficiency, respectively. Based on this result, using recycled PET can be an alternative way to produce a higher value product compared to traditional polymer membranes used commercially. This result is also supported by the neural network model of this study.
MeSH term(s)	Humans ; Filtration/methods ; Plastics ; Recycling/methods ; Positron-Emission Tomography
Chemical Substances	Plastics
Language	English
Publishing date	2022-08-05
Publishing country	Germany
Document type	Journal Article
ZDB-ID	1178791-0
ISSN	1614-7499 ; 0944-1344
ISSN (online)	1614-7499
ISSN	0944-1344
DOI	10.1007/s11356-022-22383-4
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Article ; Online: Thrombin generation assay in platelet-poor plasma in children with iron deficiency anemia.

Özdöl, Umur / Özdemir, Zeynep Canan / Töret, Ersin / Özen, Hülya / Bör, Özcan

International journal of laboratory hematology

2023 Volume 46, Issue 2, Page(s) 345–353

Abstract: Objectives: Iron deficiency anemia (IDA) is the most common type of anemia in childhood and it leads to a hypercoagulable state. We investigated endogenous thrombin production in platelet-poor plasma before and after oral iron replacement in children ... ...

Abstract	Objectives: Iron deficiency anemia (IDA) is the most common type of anemia in childhood and it leads to a hypercoagulable state. We investigated endogenous thrombin production in platelet-poor plasma before and after oral iron replacement in children with IDA using the thrombin generation assay (TGA). Methods: A total of 72 children diagnosed with IDA (IDA group) and 60 healthy children (control group) were included in the study. Blood samples were collected from the patients before and 1 month after oral iron replacement. TGA parameters [lag time, time to peak, peak height, endogenous thrombin potential (ETP)] were studied. Results: In the IDA group, the lag time and time to peak decreased by 8.3% and 10.6%, respectively, and the endogenous thrombin potential (ETP) and peak height both increased by 30% compared to those of the control group. Compared to the values before iron replacement, 1 month after iron replacement, the lag time and time to peak increased by 8.7% and 5%, respectively, and the ETP and peak height decreased by 31% and 31.3%, respectively, and became similar to those of the control group. Conclusion: Children with IDA have increased endogenous thrombin production in platelet-poor plasma and a tendency for hypercoagulability. These changes are reversible, and the ETP values become similar to those of healthy children 1 month after iron replacement.
MeSH term(s)	Child ; Humans ; Thrombin ; Anemia, Iron-Deficiency ; Blood Coagulation Tests ; Thrombophilia ; Iron
Chemical Substances	Thrombin (EC 3.4.21.5) ; Iron (E1UOL152H7)
Language	English
Publishing date	2023-12-01
Publishing country	England
Document type	Journal Article
ZDB-ID	2268590-X
ISSN	1751-553X ; 1751-5521 ; 0141-9854
ISSN (online)	1751-553X
ISSN	1751-5521 ; 0141-9854
DOI	10.1111/ijlh.14206
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Article ; Online: Differentiation of peripheral and non-peripheral etiologies in children with vertigo/dizziness: The video-head impulse test and suppression head impulse paradigm.

Kirbac, Arzu / Kaya, Ercan / Incesulu, Saziye Armagan / Carman, Kursat Bora / Yarar, Coskun / Ozen, Hulya / Pinarbasli, Mehmet Ozgur / Gurbuz, Melek Kezban

International journal of pediatric otorhinolaryngology

2024 Volume 179, Page(s) 111935

Abstract: Objectives: To identify the etiology of vertigo/dizziness and determine the effectiveness of the video-head impulse test (vHIT) and the suppression head impulse paradigm (SHIMP) tests in distinguishing between peripheral and non-peripheral etiologies in ...

Abstract	Objectives: To identify the etiology of vertigo/dizziness and determine the effectiveness of the video-head impulse test (vHIT) and the suppression head impulse paradigm (SHIMP) tests in distinguishing between peripheral and non-peripheral etiologies in children who presented to the otolaryngology department with complaints of vertigo/dizziness. Methods: The vHIT and SHIMP tests were applied to the children. The vestibulo-ocular reflex (VOR) gain and saccade parameters were compared. Results: In 27 children presenting with vertigo/dizziness, the most common etiological factor was inner ear malformation (IEM) (n = 6/27, 22.2%), followed by cochlear implant surgery (11.1%) and migraine (11.1%). Vestibular hypofunction was indicated by the vHIT results at a rate of 60% (9/15 children) and SHIMP results at 73.3% (11/15 children) among the children with a peripheral etiology, while these rates were 8.3% (1/12 children) and 25% (3/12 children), respectively, in the non-peripheral etiology group. SHIMP-VOR and vHIT-VOR gain values had a moderate positive correlation (p = 0.01, r = 0.349). While there were overt/covert saccades in the vHIT, anti-compensatory saccade (ACSs) were not observed in the SHIMP test (p = 0.041). The rates of abnormal vHIT-VOR gain (p = 0.001), over/covert saccades (p = 0.019), abnormal vHIT response (p = 0.014), ACSs (p = 0.001), and abnormal SHIMP response (p = 0.035) were significantly higher in the peripheral etiology group. Conclusions: IEM was the most common etiological cause, and the rate of vestibular hypofunction was higher in these children with peripheral vertigo. vHIT and SHIMP are effective and useful vestibular tests for distinguishing peripheral etiology from non-peripheral etiology in the pediatric population with vertigo/dizziness. These tests can be used together or alone, but the first choice should be the SHIMP test, considering its short application time (approximately 4-5 min) and simplicity.
MeSH term(s)	Child ; Humans ; Head Impulse Test/methods ; Dizziness ; Vertigo/diagnosis ; Vertigo/etiology ; Saccades ; Reflex, Vestibulo-Ocular/physiology
Language	English
Publishing date	2024-04-02
Publishing country	Ireland
Document type	Journal Article
ZDB-ID	754501-0
ISSN	1872-8464 ; 0165-5876
ISSN (online)	1872-8464
ISSN	0165-5876
DOI	10.1016/j.ijporl.2024.111935
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Article ; Online: Audio-vestibular and radiological analysis in Meniere's disease.

Kirbac, Arzu / Incesulu, Saziye Armagan / Toprak, Ugur / Caklı, Hamdı / Ozen, Hulya / Saylisoy, Suzan

Brazilian journal of otorhinolaryngology

2022 Volume 88 Suppl 3, Page(s) S117–S124

Abstract: Objective: Intravenous gadolinium-enhanced inner ear magnetic resonance imaging (IV Gd-enhanced inner ear MRI) is a new technique for diagnosing Meniere's disease (MD). Vestibular tests have also long been used for MD, but which tests should be included ...

Abstract	Objective: Intravenous gadolinium-enhanced inner ear magnetic resonance imaging (IV Gd-enhanced inner ear MRI) is a new technique for diagnosing Meniere's disease (MD). Vestibular tests have also long been used for MD, but which tests should be included in the oto-neurological test battery remains controversial. The evaluation method to be used to confirm the clinical diagnosis in MD is not clear. This study aimed to examine the results of vestibular tests and IV Gd-enhanced inner ear MRI in individuals diagnosed with unilateral definite Meniere's disease. Methods: IV Gd-enhanced inner ear MRI (Endolymphatic Hydrops [EH] and Perilymphatic Enhancement [PE]), conventional audiometry (0.25-8 kHz), video Head Impulse Test (vHIT), cervical Vestibular Evoked Myogenic Potential (cVEMP), air caloric test, and dizziness handicap inventory were applied to 16 adult patients diagnosed with unilateral definite MD. Results: Among the patients with definite MD, EH (cochlear and/or vestibular) was identified in 93.7% and 68.7% of the symptomatic and the asymptomatic ears, respectively. There was a positive correlation between the hearing thresholds at 2, 4, 6 and 8 kHz and the degree of cochlear EH (p < 0.05). PE (cochlear and/or vestibular) was observed in 37.5% of the asymptomatic and symptomatic ears. The sensitivity of the vestibular test battery (vHIT, cVEMP, and caloric test) was 100% and its specificity was 50%, while the sensitivity of the IV Gd-enhanced inner ear MRI (EH and PE together) was 93.8% and the specificity was 81.3%. Conclusion: MRI had higher sensitivity and specificity than the vestibular test battery. PE or vHIT alone was not considered to be reliable in the diagnosis of MD. In suspected MD, the clinical history, hearing tests, and IV Gd-enhanced inner ear MRI are sufficient for diagnosis. If MRI technique is not possible, vestibular tests (caloric test and cVEMP, not vHIT) can provide reliable results when evaluated together.
Language	English
Publishing date	2022-10-11
Publishing country	Brazil
Document type	Journal Article
ZDB-ID	2428110-4
ISSN	1808-8686 ; 1808-8694
ISSN (online)	1808-8686
ISSN	1808-8694
DOI	10.1016/j.bjorl.2022.08.003
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Article ; Online: Evaluation of ketogenic diet therapy in children diagnosed with drug-resistant epilepsy: a single-center experience.

Yıldırım, Gonca Kılıç / Yağcı, Murat / Uygur, Anıl Çiğdem / Özen, Hülya / Yarar, Coşkun / Çarman, Kürşat Bora

The Turkish journal of pediatrics

2022 Volume 64, Issue 3, Page(s) 435–445

Abstract: Background: We evaluate here the effect of the ketogenic diet (KD) on children with drug-resistant epilepsy (DRE) in terms of clinical effectiveness, anthropometric measurements, and some electroencephalogram (EEG) and biochemical findings.: Methods: ...

Abstract	Background: We evaluate here the effect of the ketogenic diet (KD) on children with drug-resistant epilepsy (DRE) in terms of clinical effectiveness, anthropometric measurements, and some electroencephalogram (EEG) and biochemical findings. Methods: Included in the study were 18 children (median age 70 months, 61.1% female) who received the classical KD and modified Atkins diet (MAD) for at least one year due to DRE. The patients` demographic and laboratory data; weight, height and body mass index values; EEG and electrocardiographic findings; abdominal ultrasonography findings; and biochemical parameters were recorded at baseline and at 12 months after the initiation of the diet. A reduction of ≥50% in the number of seizures was accepted as a response to KD. Results: Classic KD was chosen for 14 patients (77.8%), and MAD for four patients (22.2%). The response to KD therapy (≥50% reduction) was 55.5% (n = 10) (p = 0.008), and one patient even became seizure-free. By the 12th month of treatment, 10 patients had experienced a reduction of more than 50% in epileptiform discharges, as indicated by EEG findings. There was no difference in seizure reduction between the patients who received classical KD and MAD. A total of 11.1% of the children lost weight during KD treatment. The most common side effect was constipation (n = 10, 55.6%). At the end of one year of treatment, total cholesterol and low density lipoprotein cholesterol (LDL-C) LDL-C levels had increased dramatically, while fasting blood glucose levels had decreased significantly. Conclusions: Our study suggests that KD treatment provides good clinical efficacy in the treatment of pediatric DRE, and can significantly reduce the frequency of epileptic discharges. Also, total cholesterol and LDL-C levels increased significantly, and fasting blood glucose levels decreased significantly compared to the baseline levels.
MeSH term(s)	Blood Glucose ; Child, Preschool ; Cholesterol, LDL ; Diet, Carbohydrate-Restricted ; Diet, Ketogenic/adverse effects ; Drug Resistant Epilepsy ; Epilepsy ; Female ; Humans ; Male ; Seizures ; Treatment Outcome
Chemical Substances	Blood Glucose ; Cholesterol, LDL
Language	English
Publishing date	2022-07-28
Publishing country	Turkey
Document type	Journal Article
ZDB-ID	123487-0
ISSN	2791-6421 ; 0041-4301
ISSN (online)	2791-6421
ISSN	0041-4301
DOI	10.24953/turkjped.2020.3091
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Article: Investigation of Factors Influencing Thoroughbred Horses' Racing Career Length in Turkey

Özen, Doğukan / Kaya, Ufuk / Özen, Hülya / Ambarcioğlu, Pınar / Ünal, Necmettin / Gürcan, İsmayil Safa

Journal of equine veterinary science. 2021 Dec., v. 107

2021

Abstract: The aim of this research was to determine the average length of a Thoroughbred horse's racing career in Turkey using survival functions of Thoroughbred horses with various characteristics. In addition, the aim was to identify risk factors that could ... ...

Abstract	The aim of this research was to determine the average length of a Thoroughbred horse's racing career in Turkey using survival functions of Thoroughbred horses with various characteristics. In addition, the aim was to identify risk factors that could influence the duration of a Thoroughbred horse's racing career and develop a survival model that took these factors into account. A total of 11,721 Thoroughbred horses born in 2007 and later were included in the study population. The horses involved in the study were followed for a minimum of 1 year. Kaplan-Meier analysis was used to calculate the average length of racing career for each factor studied. Extended Cox regression analysis was used to determine the risk factors upon time of career ending and to create a survival model. Results showed that, the mean career length of Thoroughbred horses was 17.79 months (95% CI: 17.41–18.13). Also, "starting age of the race," "number of starts," "type of track where the race started," "racing on a single type racetrack" and "earning status" were found risk factors that affect the length of the racing career. Earnings was the top relative contributor to the established model, and its sole adjusted effect showed that being in the lowest earning group increased the hazard of career ending 2.28 times (95% CI:1.98–2.61) compared to horses with highest earning group. In conclusion, clear differences upon the length of racing career was observed for each investigated factor. Future studies should be considerate of these differences when analyzing population data.
Keywords	Thoroughbred ; horses ; models ; regression analysis ; veterinary medicine
Language	English
Dates of publication	2021-12
Publishing place	Elsevier Inc.
Document type	Article
ZDB-ID	2102631-2
ISSN	1542-7412 ; 0737-0806
ISSN (online)	1542-7412
ISSN	0737-0806
DOI	10.1016/j.jevs.2021.103782
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Article ; Online: Relationship between oxidant-antioxidant status and hypercoagulobility indices in children with iron deficiency anaemia.

Özdemir, Zeynep Canan / Çolak, Emine / Kar, Yeter Düzenli / Özen, Hülya / Bör, Özcan

Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis

2021 Volume 32, Issue 7, Page(s) 451–457

Abstract: Oxidative stress is a potential mechanism involved in the pathogenesis of iron deficiency anaemia (IDA). Although a tendency for hypercoagulability has been reported in IDA, its underlying mechanism is yet to be elucidated. This study investigated the ... ...

Abstract	Oxidative stress is a potential mechanism involved in the pathogenesis of iron deficiency anaemia (IDA). Although a tendency for hypercoagulability has been reported in IDA, its underlying mechanism is yet to be elucidated. This study investigated the probable relationship between oxidative stress and hypercoagulability in children with IDA. This study included 57 children diagnosed with IDA (IDA group) between October 2016 and October 2017 in addition to 48 healthy children (control group). The maximum clot firmness (MCF) index, and clot formation time (CFT) index, which are indicators of hypercoagulability in rotational thromboelastometry assays [intrinsic TEM (INTEM) and extrinsic TEM (EXTEM)] derived from our previous study, were recorded. Total oxidant status (TOS), total antioxidant capacity (TAC) and oxidative stress index (OSI) were analysed from serum samples of the individuals. In IDA group, OSI and TOS levels were higher and TAC level was lower compared to the control group (P < 0.001, for all). The EXTEM and INTEM MCF in the IDA group was higher than in the control group, while the INTEM CFT was lower than in the control group (P < 0.001, P < 0.001, P < 0.05, published data).TOS and OSI had a negative correlation with INTEM CFT (r:-0.361, P < 0.001 and r:-0.333, P = 0.001) and a positive correlation with INTEM MCF (r:+0.420, P < 0.001 and r:+0.367, P < 0.001) and EXTEM MCF (r:+0.476, P < 0.001 and r:+0.403, P < 0.001). However, TAC demonstrated no correlation with CFT and MCF index. The oxidant-antioxidant balance is disrupted in favour of oxidative stress in children with IDA. In addition, TOS and OSI, which are parameters of oxidative stress, are correlated with CFT and MCF indices. Oxidative stress appears to be an important factor for the development of tendency to hypercoagulability in IDA.
MeSH term(s)	Adolescent ; Anemia, Iron-Deficiency/blood ; Anemia, Iron-Deficiency/complications ; Anemia, Iron-Deficiency/metabolism ; Blood Coagulation ; Child ; Child, Preschool ; Female ; Humans ; Male ; Oxidative Stress ; Thrombophilia/blood ; Thrombophilia/complications ; Thrombophilia/metabolism
Language	English
Publishing date	2021-07-09
Publishing country	England
Document type	Journal Article
ZDB-ID	1033551-1
ISSN	1473-5733 ; 0957-5235
ISSN (online)	1473-5733
ISSN	0957-5235
DOI	10.1097/MBC.0000000000001060
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