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  1. Article ; Online: An extended view for acoustofluidic particle manipulation: Scenarios for actuation modes and device resonance phenomenon for bulk-acoustic-wave devices.

    Özer, M Bülent / Çetin, Barbaros

    The Journal of the Acoustical Society of America

    2021  Volume 149, Issue 4, Page(s) 2802

    Abstract: For the manipulation of microparticles, ultrasonic devices, which employ acoustophoretic forces, have become an essential tool. There exists a widely used analytical expression in the literature which does not account for the effect of the geometry and ... ...

    Abstract For the manipulation of microparticles, ultrasonic devices, which employ acoustophoretic forces, have become an essential tool. There exists a widely used analytical expression in the literature which does not account for the effect of the geometry and acoustic properties of the chip material to calculate the acoustophoretic force and resonance frequencies. In this study, we propose an analytical relationship that includes the effect of the chip material on the resonance frequencies of an acoustophoretic chip. Similar to the analytical equation in the literature, this approach also assumes plane wave propagation. The relationship is simplified to a form which introduces a correction term to the acoustophoretic force equation for the presence of the chip material. The proposed equations reveal that the effect of the chip material on the resonance frequency is significant-and is called the device resonance-for acoustically soft materials. The relationship between the actuation modes of the piezoelectric actuator(s) and position of the nodal lines inside the channel are discussed. Finite element simulations are performed to verify the proposed equations. Simulations showed that even if some of the assumptions in the derivations are removed, the general conclusions about the motion of the microparticles are still valid.
    Language English
    Publishing date 2021-05-04
    Publishing country United States
    Document type Journal Article
    ZDB-ID 219231-7
    ISSN 1520-8524 ; 0001-4966
    ISSN (online) 1520-8524
    ISSN 0001-4966
    DOI 10.1121/10.0004778
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 591: Show issues Location:
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  2. Article ; Online: Assessment of silicon, glass, FR4, PDMS and PMMA as a chip material for acoustic particle/cell manipulation in microfluidics.

    Açıkgöz, Hande N / Karaman, Alara / Şahin, M Akif / Çaylan, Ömer R / Büke, Göknur C / Yıldırım, Ender / Eroğlu, İrem C / Erson-Bensan, A Elif / Çetin, Barbaros / Özer, M Bülent

    Ultrasonics

    2022  Volume 129, Page(s) 106911

    Abstract: In the present study, the capabilities of different chip materials for acoustic particle manipulation have been assessed with the same microfluidic device architecture, under the same actuator and flow conditions. Silicon, glass, epoxy with fiberglass ... ...

    Abstract In the present study, the capabilities of different chip materials for acoustic particle manipulation have been assessed with the same microfluidic device architecture, under the same actuator and flow conditions. Silicon, glass, epoxy with fiberglass filling (FR4), polydimethylsiloxane (PDMS) and polymethyl methacrylate (PMMA) are considered as chip materials. The acoustophoretic chips in this study were manufactured with four different fabrication methods: plasma etching, chemical etching, micromachining and molding. A novel chip material, FR4, has been employed as a microfluidic chip material in acoustophoretic particle manipulation for the first time in literature, which combines the ease of manufacturing of polymer materials with improved acoustic performance. The acoustic particle manipulation performance is evaluated through acoustophoretic focusing experiments with 2μm and 12μm polystyrene microspheres and cultured breast cancer cell line (MDA-MB-231). Unlike the common approach in the literature, the piezoelectric materials were actuated with partitioned cross-polarized electrodes which allowed effective actuation of different family of chip materials. Different from previous studies, this study evaluates the performance of each acoustophoretic device through the perspective of synchronization of electrical, vibrational and acoustical resonances, considers the thermal performance of the chip materials with their effects on cell viability as well as manufacturability and scalability of their fabrication methods. We believe our study is an essential work towards the commercialization of acoustophoretic devices since it brings a critical understanding of the effect of chip material on device performance as well as the cost of achieving that performance.
    MeSH term(s) Microfluidics ; Polymethyl Methacrylate ; Silicon ; Acoustics ; Dimethylpolysiloxanes
    Chemical Substances Polymethyl Methacrylate (9011-14-7) ; Silicon (Z4152N8IUI) ; baysilon (63148-62-9) ; Dimethylpolysiloxanes
    Language English
    Publishing date 2022-12-09
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 200839-7
    ISSN 1874-9968 ; 0041-624X
    ISSN (online) 1874-9968
    ISSN 0041-624X
    DOI 10.1016/j.ultras.2022.106911
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Passively minimizing structural sound radiation using shunted piezoelectric materials.

    Ozer, M Bulent / Royston, Thomas J

    The Journal of the Acoustical Society of America

    2003  Volume 114, Issue 4 Pt 1, Page(s) 1934–1946

    Abstract: Two methods are presented to determine optimal inductance and resistance values of the shunt circuit across a piezoceramic material, which is bonded to a simply supported plate in order to minimize sound radiation from the plate. The first method (DH) ... ...

    Abstract Two methods are presented to determine optimal inductance and resistance values of the shunt circuit across a piezoceramic material, which is bonded to a simply supported plate in order to minimize sound radiation from the plate. The first method (DH) makes use of den Hartog's damped vibration absorber principle. The second method (SM) uses the Sherman Morrison matrix inversion theorem. The effectiveness of each method is compared with regard to minimizing total acoustic sound-power radiation and acoustic pressure at a point. Optimization algorithms and case studies are presented using a linearized model for the piezoceramic and using a nonlinear model for the piezoceramic that accounts for the inherent dielectric hysteresis. Case studies demonstrate that the second method (SM) results in superior performance, under both linear and nonlinear system assumptions. Studies also illustrate that, if the nonlinearity in the system is significant, it must be incorporated in the optimization process.
    Language English
    Publishing date 2003-09-17
    Publishing country United States
    Document type Journal Article
    ZDB-ID 219231-7
    ISSN 1520-8524 ; 0001-4966
    ISSN (online) 1520-8524
    ISSN 0001-4966
    DOI 10.1121/1.1605390
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 591: Show issues Location:
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    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
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    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

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