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  1. Article ; Online: Tricuspid repair: short and long-term results of suture annuloplasty techniques and rigid and flexible ring annuloplasty techniques.

    Türkmen, Ufuk / Bozkurt, Tezcan / Özyalçın, Sertan / Günaydın, Ilknur / Kaplan, Sadi

    Journal of cardiothoracic surgery

    2024  Volume 19, Issue 1, Page(s) 158

    Abstract: Background: Functional tricuspid regurgitation may arise from left heart valve diseases or other factors. If not addressed concurrently with primary surgical intervention, it may contribute to increased morbidity and mortality rates during the ... ...

    Abstract Background: Functional tricuspid regurgitation may arise from left heart valve diseases or other factors. If not addressed concurrently with primary surgical intervention, it may contribute to increased morbidity and mortality rates during the postoperative period. This study investigates the impact of various repair techniques on crucial factors such as systolic pulmonary artery pressure (SPAP), tricuspid valve regurgitation, and New York Heart Association (NYHA) functional capacity class in the postoperative period.
    Materials and methods: From April 2007 to June 2013, 379 adults underwent open-heart surgery for functional tricuspid regurgitation. Patients were categorized into four groups: Group 1 (156) with De Vega suture annuloplasty, Group 2 (60) with Kay suture annuloplasty, Group 3 (122) with Flexible Duran ring annuloplasty, and Group 4 (41) with Semi-Rigid Carpentier-Edwards ring annuloplasty. Demographic, clinical, operative, and postoperative data were recorded over a mean follow-up of 35.6 ± 19.1 months. Postoperative SPAP values, tricuspid regurgitation grades, and NYHA functional capacity classes were compared among the groups.
    Results: No statistically significant differences were observed among the groups regarding age, gender, preoperative disease diagnoses, history of previous cardiac operations, or echocardiographic characteristics such as preoperative ejection fraction, SPAP, and tricuspid regurgitation. Hospital and intensive care unit length of stay and postoperative complications also showed no significant differences. However, patients in Group 3 exhibited longer Cardio-Pulmonary Bypass duration, cross-clamp duration, and higher positive inotrope requirements. While the mortality rate within the first 30 days was higher in Group 1 compared to the other groups (p: 0.011), overall mortality rates did not significantly differ among the groups. Significant regression in functional tricuspid regurgitation and a notable decrease in SPAP values were observed in patients from Group 3 and Group 4 (p: 0.001). Additionally, patients in Group 3 and Group 4 showed a more significant reduction in NYHA functional capacity classification during the postoperative period (p: 0.001).
    Conclusion: Among the repair techniques, ring annuloplasty demonstrated superiority in reducing SPAP, regressing tricuspid regurgitation, and improving NYHA functional capacity in functional tricuspid regurgitation repairs.
    MeSH term(s) Adult ; Humans ; Tricuspid Valve Insufficiency/surgery ; Tricuspid Valve Insufficiency/diagnosis ; Heart Valve Prosthesis Implantation/methods ; Treatment Outcome ; Tricuspid Valve/surgery ; Mitral Valve/surgery ; Cardiac Valve Annuloplasty ; Suture Techniques
    Language English
    Publishing date 2024-03-27
    Publishing country England
    Document type Journal Article
    ZDB-ID 2227224-0
    ISSN 1749-8090 ; 1749-8090
    ISSN (online) 1749-8090
    ISSN 1749-8090
    DOI 10.1186/s13019-024-02640-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: The impact of spontaneous echo contrast on tunneled dialysis catheter patency.

    Özyalçın, Sertan / Topçu, Hülya

    The journal of vascular access

    2021  Volume 24, Issue 3, Page(s) 423–429

    Abstract: Background: Spontaneous echo contrast (SEC) is an ultrasonographic image of swirling blood flow resembling a dynamic, cigarette smoke-like image. It is mostly observed during the insertion of tunneled dialysis catheters (TDC) into internal jugular veins ...

    Abstract Background: Spontaneous echo contrast (SEC) is an ultrasonographic image of swirling blood flow resembling a dynamic, cigarette smoke-like image. It is mostly observed during the insertion of tunneled dialysis catheters (TDC) into internal jugular veins with ultrasound guidance, often different levels of SEC can be seen. The aim of this study is to investigate the impact of SEC detected during TDC insertion on the patency of the catheter.
    Methods: Patients who had a TDC insertion in our clinic between January 2015 and December 2020 were prospectively evaluated. The patients were grouped into five groups according to the sec level and followed.
    Results: A total of 226 patients were examined, among which 107 were male (47.3%). The mean age of all patients was 63.1 ± 9.5 years. SEC grade and catheter occlusion was evaluated, it was observed that higher SEC grades were correlated with faster catheter thrombosis postinsertion. During the follow-up period, it was found that, compared to the SEC 0 group, catheter thrombosis occurred 3.22 times faster in the SEC 1 group, 2.66 times faster in the SEC 2 group, 5.80 times faster in the SEC 3 group, and 26.33 times faster in the SEC 4 group. (HR: 3.22, 2.66, 5.80, 26.33, respectively). Hematological parameters were evaluated by regression analysis, it was observed that hemoglobin, fibrinogen, and platelet count were not risk factors for SEC formation and SEC grade.
    Conclusion: Significant relationship was found between SEC grade detected during catheter insertion and catheter thrombosis in patients undergoing hemodialysis with a TDC.
    MeSH term(s) Humans ; Male ; Middle Aged ; Aged ; Female ; Renal Dialysis/adverse effects ; Catheters, Indwelling/adverse effects ; Treatment Outcome ; Catheterization/adverse effects ; Thrombosis/etiology ; Catheterization, Central Venous/adverse effects ; Catheterization, Central Venous/methods ; Retrospective Studies
    Language English
    Publishing date 2021-07-29
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2252820-9
    ISSN 1724-6032 ; 1129-7298
    ISSN (online) 1724-6032
    ISSN 1129-7298
    DOI 10.1177/11297298211035599
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Predicting Amputation Rates in Acute Limb Ischemia: Is the Neutrophil-Lymphocyte Ratio a Reliable Indicator?

    Erol, Mehmet Emir / Civelek, İsa / Ozyalcin, Sertan / Beyazpınar, Deniz Sarp / Kandemir, Ozer

    Cureus

    2024  Volume 16, Issue 4, Page(s) e59253

    Abstract: Objective This study aimed to investigate the causes of amputation and the associated biochemical parameters in patients with acute limb ischemia (ALI). Methods Patients who presented to our clinic with ALI between January 2012 and January 2022 were ... ...

    Abstract Objective This study aimed to investigate the causes of amputation and the associated biochemical parameters in patients with acute limb ischemia (ALI). Methods Patients who presented to our clinic with ALI between January 2012 and January 2022 were deemed eligible for participation. Patients who developed ALI owing to atherosclerosis or atrial fibrillation were included in the study. In contrast, patients who developed ALI owing to trauma, iatrogenic causes, or popliteal artery aneurysms were excluded. Patients' demographic data, biochemical parameters, and hemogram values at the time of admission were retrospectively analyzed. Results A total of 374 patients were included in the study. Of them, 57.82% (n = 218) were male and 42.18% (n= 156) were female. Amputation was required in 7.95% (n = 30) of the patients after presenting with ALI and receiving necessary surgical or medical intervention. Multivariate analysis revealed the symptom-to-door time to be the primary factor determining the need for amputation in patients. With each passing hour following the manifestation of symptoms, the risk of amputation increased by 1.3 times [odds ratio (OR): 1.289%, 95% confidence interval (CI): 1.079-1.540 p = 0.05]. The neutrophil-to-lymphocyte ratio (NLR) and other hematological parameters had no effect on amputation in both univariate and multivariate analyses (OR: 1.49%; 95% CI: 0.977-2.287 p = 0.512). Conclusions Based on our findings, the main factor affecting the need for amputation in ALI patients was the symptom-to-door time. Biochemical and hematological parameters had no effect on amputation in ALI.
    Language English
    Publishing date 2024-04-29
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.59253
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Factors Affecting Recanalization in Femoropopliteal Deep Vein Thrombosis.

    Erol, Mehmet Emir / Özyalçın, Sertan / Tekin, Kudret Atakan / Diken, Adem İlkay / Yalçınkaya, Adnan / Ünal, Ertekin Utku

    Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis

    2023  Volume 29, Page(s) 10760296231173409

    Abstract: Effects of warfarin and new-generation direct oral anticoagulants (DOACs) on thrombus resolution after the treatment of deep vein thrombosis (DVT) are still unknown. The study aimed to investigate the effects of warfarin and DOACs on thrombus resolution ... ...

    Abstract Effects of warfarin and new-generation direct oral anticoagulants (DOACs) on thrombus resolution after the treatment of deep vein thrombosis (DVT) are still unknown. The study aimed to investigate the effects of warfarin and DOACs on thrombus resolution after DVT treatment.
    MeSH term(s) Humans ; Venous Thrombosis/diagnostic imaging ; Venous Thrombosis/drug therapy ; Warfarin/therapeutic use ; Popliteal Vein/diagnostic imaging ; Thrombosis/drug therapy ; Ultrasonography ; Anticoagulants/therapeutic use ; Treatment Outcome
    Chemical Substances Warfarin (5Q7ZVV76EI) ; Anticoagulants
    Language English
    Publishing date 2023-05-10
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1237357-6
    ISSN 1938-2723 ; 1076-0296
    ISSN (online) 1938-2723
    ISSN 1076-0296
    DOI 10.1177/10760296231173409
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Radiofrequency ablation of the great saphenous vein; does the choice of monopolar or bipolar catheters affect outcomes?

    Diken, Adem I / Özyalçın, Sertan / Hafez, İzzet / Alemdaroğlu, Utku / Tünel, Hüseyin A / Hanedan, Onur

    Phlebology

    2023  Volume 38, Issue 6, Page(s) 361–369

    Abstract: Objectives: Radiofrequency-based procedure is one of the leading methods of endovenous thermal ablation. The most fundamental difference with regards to currently available radiofrequency ablation systems is the way of electric current flow given to the ...

    Abstract Objectives: Radiofrequency-based procedure is one of the leading methods of endovenous thermal ablation. The most fundamental difference with regards to currently available radiofrequency ablation systems is the way of electric current flow given to the vein wall; bipolar segmental and monopolar ablation. This study aimed to compare the monopolar ablation method with conventional bipolar segmental endovenous radiofrequency ablation method for the management of incompetent saphenous veins.
    Methods: Between November 2019 and November 2021, 121 patients with incompetent varicose veins who were treated either with the F-Care/monopolar (
    Results: There was no statistically significant difference between the groups regarding demographic parameters, disease severity, and treated veins in preoperative period (
    Conclusions: Both systems are effective in treating the venous insufficiency of the lower extremity. Monopolar system revealed a better early postoperative course with similar occlusion rate of the proximal part of saphenous vein compared with bipolar system, however; the occlusion of the lower half of the saphenous vein was significantly lower which may negatively affect long-term occlusion rates and recurrence of the disease.
    MeSH term(s) Humans ; Saphenous Vein/surgery ; Retrospective Studies ; Catheter Ablation/adverse effects ; Catheter Ablation/methods ; Varicose Veins/therapy ; Venous Insufficiency/therapy ; Treatment Outcome ; Radiofrequency Ablation ; Postoperative Complications ; Catheters
    Language English
    Publishing date 2023-05-08
    Publishing country England
    Document type Journal Article
    ZDB-ID 645172-x
    ISSN 1758-1125 ; 0268-3555
    ISSN (online) 1758-1125
    ISSN 0268-3555
    DOI 10.1177/02683555231174997
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Atrial Fibrillation after Coronary Bypass Surgery? Is Epicardial Fat a Risk Factor?

    Yalçınkaya, Adnan / Fidan, Nurdan / Sarı, Engin / Özyalçın, Sertan / Diken, Adem İlkay

    The Thoracic and cardiovascular surgeon

    2022  Volume 71, Issue 4, Page(s) 291–296

    Abstract: Backgrounds: Postoperative atrial fibrillation (POAF) is one of the most common complication of cardiac surgery. Epicardial fat tissue may play a role in the development of atrial fibrillation (AF). The aim of this study was to evaluate relationship ... ...

    Abstract Backgrounds: Postoperative atrial fibrillation (POAF) is one of the most common complication of cardiac surgery. Epicardial fat tissue may play a role in the development of atrial fibrillation (AF). The aim of this study was to evaluate relationship between epicardial fat volume (EFV) and the appearance of new-onset AF in patients undergoing isolated coronary artery bypass graft (CABG) with normal echocardiographic functions.
    Methods: Between January 2017 and June 2020, 281 coronary artery disease patients undergone isolated CABG surgery with normal echocardiographic functions were included in the study. Patient characteristics, medical history, and perioperative variables were retrospectively collected. Patients with AF predisposition factors were excluded.
    Results: Sixty-seven patients (23.8%) developed postoperatively AF during hospital stay. In univariate analysis, patients with postoperative AF were older compared with sinus rhythm patients (60.78 ± 9.03 vs. 65.46 ± 9.22,
    Conclusion: Aging is the only associated factor with AF in this study. There was no EFV difference between POAF and non-AF groups in patients undergoing isolated CABG with normal echocardiographic functions.
    MeSH term(s) Humans ; Female ; Atrial Fibrillation ; Retrospective Studies ; Postoperative Complications/etiology ; Treatment Outcome ; Coronary Artery Bypass/adverse effects ; Risk Factors
    Language English
    Publishing date 2022-07-27
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 800050-5
    ISSN 1439-1902 ; 0171-6425 ; 0946-4778 ; 0172-6137
    ISSN (online) 1439-1902
    ISSN 0171-6425 ; 0946-4778 ; 0172-6137
    DOI 10.1055/s-0042-1750787
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Biocompatibility of the Oxygenator on Pulsatile Flow by Electron Microscope.

    Ulus, Ahmet Tulga / Güray, Tuna / Ürpermez, Ece / Özyalçın, Sertan / Taner, Ali / Haberal, Erdem / Kocakulak, Mustafa

    Brazilian journal of cardiovascular surgery

    2023  Volume 38, Issue 1, Page(s) 62–70

    Abstract: Introduction: Extracorporeal perfusion flow type requires further investigation. The aim of this study is to compare the effects of pulsatile and nonpulsatile flow on oxygenator fibers that were analyzed by scanning electron microscope (SEM) and to ... ...

    Abstract Introduction: Extracorporeal perfusion flow type requires further investigation. The aim of this study is to compare the effects of pulsatile and nonpulsatile flow on oxygenator fibers that were analyzed by scanning electron microscope (SEM) and to extensively study patients' coagulation profiles, inflammatory markers, and functional blood tests.
    Methods: Twelve patients who had open heart surgery were randomly divided into two groups; the nonpulsatile flow (group NP, six patients) and pulsatile flow (group P, six patients) groups. Both superficial view and axial sections of the oxygenator fiber samples were examined under SEM to compare the thickness of absorbed blood proteins and amount of blood cells on the surface of oxygenators. Platelet count, coagulation profile, and inflammatory predictors were also studied from the blood samples.
    Results: Fibrinogen levels after cardiopulmonary bypass were significantly lower in group NP (group P, 2.57±2.78 g/L; group NP; 2.39±0.70 g/L, P=0.03). Inflammatory biomarkers such as C-reactive protein, interleukin (IL)-6, IL-12, apelin, S100β, and tumor necrosis factor alpha were comparable in both groups. Axial sections of the oxygenator fiber samples had a mean thickness of 45.2 µm and 46.5 µm in groups P and NP, respectively, and this difference is statistically significant (P=0.006). Superficial view of the fiber samples showed obviously lower platelet, leukocyte, and erythrocyte levels in group P.
    Conclusion: Our study demonstrated that both cellular elements and protein adsorption on oxygenator fibers are lower in the group P than in the group NP. Pulsatile perfusion has better biocompatibility on extracorporeal circulation when analyzed by SEM technique.
    MeSH term(s) Humans ; Oxygenators, Membrane ; Pulsatile Flow ; Electrons ; Extracorporeal Circulation ; Cardiopulmonary Bypass/methods ; Interleukin-6
    Chemical Substances Interleukin-6
    Language English
    Publishing date 2023-02-10
    Publishing country Brazil
    Document type Randomized Controlled Trial ; Journal Article
    ZDB-ID 2031026-2
    ISSN 1678-9741 ; 1678-9741
    ISSN (online) 1678-9741
    ISSN 1678-9741
    DOI 10.21470/1678-9741-2021-0519
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Carotid artery stenosis in asymptomatic patients undergoing coronary artery bypass grafting: who and when should be screened?

    Özyalçın, Sertan / Diken, Adem İlkay / Yalçınkaya, Adnan / Türkmen, Ufuk

    Kardiologia polska

    2020  Volume 79, Issue 1, Page(s) 25–30

    Abstract: Background: Carotid artery stenosis (CAS) is one of the major causes of stroke in coronary artery bypass grafting (CABG).: Aims: The aim of this study was to determine which age groups require screening for CAS using carotid duplex ultrasound in ... ...

    Abstract Background: Carotid artery stenosis (CAS) is one of the major causes of stroke in coronary artery bypass grafting (CABG).
    Aims: The aim of this study was to determine which age groups require screening for CAS using carotid duplex ultrasound in asymptomatic patients undergoing CABG.
    Methods: We included 644 neurologically asymptomatic consecutive patients (mean [SD] age, 63.9 [8.8] years; men, 453 [70.3%]) who underwent elective isolated CABG between June 2015 and June 2020. Clinical, demographic, and radiological data as well as coronary angiography results were retrospectively reviewed. Patients were classified into 4 age groups: 40 to 50, 51 to 60, 61 to 70, and >70 years, as well as 3 groups depending on the CAS degree: 50% or less, 50% to 70%, and 70% or greater. Regression analysis was applied across the selected parameters to identify risk factors for significant CAS, and receiver operating characteristic analysis, to determine cutoff age and SYNTAX score of patients who had to be screened before CABG.
    Results: Overall, 8 (1.1%) patients included in the present study had stroke following CABG. Cutoff values of the SYNTAX score and CAS of 70% or greater were found to be 27 and 64 years, respectively. The sensitivity and specificity of the cutoff value were 98.4% to 98.3% and 74.3% to 55.1%, respectively. The area under the curve was 0.98 and 0.73, respectively.
    Conclusion: Based on the receiver operating characteristic analysis, we recommended to perform screening for CAS in patients older than 64 years and with a SYNTAX score of 27 or higher, even if they are asymptomatic.
    MeSH term(s) Adult ; Carotid Stenosis/complications ; Carotid Stenosis/diagnostic imaging ; Carotid Stenosis/surgery ; Child ; Coronary Artery Bypass ; Coronary Artery Disease ; Humans ; Male ; Middle Aged ; Retrospective Studies ; Risk Factors ; Stroke ; Treatment Outcome
    Language English
    Publishing date 2020-10-16
    Publishing country Poland
    Document type Journal Article
    ZDB-ID 411492-9
    ISSN 1897-4279 ; 0022-9032
    ISSN (online) 1897-4279
    ISSN 0022-9032
    DOI 10.33963/KP.15649
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Atrial Fibrillation after Coronary Bypass Surgery? Is Epicardial Fat a Risk Factor?

    Yalçınkaya, Adnan / Fidan, Nurdan / Sarı, Engin / Özyalçın, Sertan / Diken, Adem İlkay

    The Thoracic and Cardiovascular Surgeon

    2022  Volume 71, Issue 04, Page(s) 291–296

    Abstract: Backgrounds: Postoperative atrial fibrillation (POAF) is one of the most common complication of cardiac surgery. Epicardial fat tissue may play a role in the development of atrial fibrillation (AF). The aim of this study was to evaluate relationship ... ...

    Abstract Backgrounds: Postoperative atrial fibrillation (POAF) is one of the most common complication of cardiac surgery. Epicardial fat tissue may play a role in the development of atrial fibrillation (AF). The aim of this study was to evaluate relationship between epicardial fat volume (EFV) and the appearance of new-onset AF in patients undergoing isolated coronary artery bypass graft (CABG) with normal echocardiographic functions.
    Methods: Between January 2017 and June 2020, 281 coronary artery disease patients undergone isolated CABG surgery with normal echocardiographic functions were included in the study. Patient characteristics, medical history, and perioperative variables were retrospectively collected. Patients with AF predisposition factors were excluded.
    Results: Sixty-seven patients (23.8%) developed postoperatively AF during hospital stay. In univariate analysis, patients with postoperative AF were older compared with sinus rhythm patients (60.78 ± 9.03 vs. 65.46 ± 9.22, p  = 0.001). There are no statistically significant differences between groups and EFV compared (107.78 ± 41.04 vs. 106.66 ± 34.98 p  = 0.84). Large left atrial diameter, female patient, cardiopulmonary bypass and longer cross-clamp time showed correlation between POAF without statistical significance.
    Conclusion: Aging is the only associated factor with AF in this study. There was no EFV difference between POAF and non-AF groups in patients undergoing isolated CABG with normal echocardiographic functions.
    Keywords coronary artery bypass grafts surgery ; CABG ; arrhythmia therapy ; cardiac anatomy/pathologic anatomy
    Language English
    Publishing date 2022-07-27
    Publisher Georg Thieme Verlag KG
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 800050-5
    ISSN 1439-1902 ; 0171-6425 ; 0946-4778 ; 0172-6137
    ISSN (online) 1439-1902
    ISSN 0171-6425 ; 0946-4778 ; 0172-6137
    DOI 10.1055/s-0042-1750787
    Database Thieme publisher's database

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  10. Article: Distribution of Thoracic Aortic Calcifications in Patients Undergoing Coronary Artery Bypass Grafting.

    Diken, Adem Ilkay / Yalçınkaya, Adnan / Özyalçın, Sertan

    Aorta (Stamford, Conn.)

    2017  Volume 5, Issue 5, Page(s) 132–138

    Abstract: Background: In procedures involving surgical maneuvers such as cannulation, clamping, or proximal anastomosis where aortic manipulation is inevitable, a preliminary assessment of atherosclerotic plaques bears clinical significance. In the present study, ...

    Abstract Background: In procedures involving surgical maneuvers such as cannulation, clamping, or proximal anastomosis where aortic manipulation is inevitable, a preliminary assessment of atherosclerotic plaques bears clinical significance. In the present study, our aim was to evaluate the frequency and distribution of aortic calcifications in patients undergoing coronary artery bypass grafting (CABG) surgery to propose a morphological classification system.
    Methods: A total of 443 consecutive patients with coronary artery disease were included in this study. Preoperative non-contrast enhanced computed tomography images, in-hospital follow-up data, and patient characteristics were retrospectively evaluated.
    Results: Whereas 33% of patients had no calcifications at any site in the aorta, 7.9%, 75.4%, and 16.7% had calcifications in the ascending aorta, aortic arch, and descending aorta, respectively. Focal small calcifications were the most common type of lesions in the ascending aorta (3.9%), whereas 9 patients (1.4%) had porcelain ascending aorta. We defined four types of patients with increasing severity and extent of calcifications.
    Conclusions: Based on the frequency and distribution of calcifications in the thoracic aorta, we propose a classification system from least to most severe for coronary artery disease patients who are candidates for CABG.
    Language English
    Publishing date 2017-10-01
    Publishing country Germany
    Document type Journal Article
    ISSN 2325-4637
    ISSN 2325-4637
    DOI 10.12945/j.aorta.2017.17.035
    Database MEDical Literature Analysis and Retrieval System OnLINE

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