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  1. Article: Social and Medical Characteristics of Neonates Who Were Abandoned in a Tertiary Maternity Hospital in Turkey.

    Sattarova, Shahla / Öncel, Mehmet Yekta / Üstün, Hüseyin / Karabulut Gencay, Sakine / Engür, Defne

    Turkish archives of pediatrics

    2023  Volume 58, Issue 5, Page(s) 480–484

    Abstract: Objective: This study aimed to investigate the characteristics of neonates who were aban- doned in a tertiary maternity hospital and to determine the accompanying morbidities.: Materials and methods: This hospital-based, retrospective descriptive ... ...

    Abstract Objective: This study aimed to investigate the characteristics of neonates who were aban- doned in a tertiary maternity hospital and to determine the accompanying morbidities.
    Materials and methods: This hospital-based, retrospective descriptive study was conducted by evaluating the medical records between 2012 and 2019 in a tertiary hospital in İzmir.
    Results: During the study period, there were 76 women who left their babies in the hospital following delivery. Median age of the mothers was 23 (range 12-44) years. Among them, 31.5% (n = 24) were below 18 years of age. Seventy-three of the pregnancies (96%) were unwanted, 67 of the mothers were unmarried (88.16%), of which 17 revealed a history of rape (22.36%), and 2 of them were victims of incest (2.63%). Thirty-six (47.36%) neonates were female and 36 of them (47.36%) were delivered by cesarean section. The mean gestational age was 37.3 ± 2.2 weeks and the mean birth weight was 2927 ± 572 g. Twenty-one (27.63%) babies were born prematurely and 15 (19.73%) had low birth weight. Four babies (5.26%) had hypoglycemia, 3 (3.94%) had hyponatremia, 5 (6.57%) had hypocalcemia, and 3 (3.94%) had hypomagnesemia.
    Conclusion: Unwanted pregnancies were found to be one of the key reasons for newborn aban- donment and linked to a higher risk of complications for both mother and child. To prevent unintended pregnancy and its negative effects, it is important to ensure that all adolescents have access to high-quality education in a safe and supportive learning environment, school- based health services, and increase access to contraceptive services, including emergency contraception and safe and legal abortion services.
    Language English
    Publishing date 2023-08-09
    Publishing country Turkey
    Document type Journal Article
    ISSN 2757-6256
    ISSN 2757-6256
    DOI 10.5152/TurkArchPediatr.2023.23040
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Bilirubin Measurement Through a Smartphone Application in Preterm Infants.

    Ustun, Huseyin / Oncel, Mehmet Yekta / Kefeli, Melike / Akar, Melek / Engür, Defne

    Klinische Padiatrie

    2022  Volume 235, Issue 5, Page(s) 265–269

    Abstract: Backround: Aim of the present study is to evaluate the feasibility and reliability of an smartphone application for monitore of bilirubin levels in preterm infants.: Methods: Preterm infants hospitalized in the neonatal intensive care unit with ... ...

    Title translation Bilirubin-Bestimmung mittels Smartphone-App bei Frühgeborenen.
    Abstract Backround: Aim of the present study is to evaluate the feasibility and reliability of an smartphone application for monitore of bilirubin levels in preterm infants.
    Methods: Preterm infants hospitalized in the neonatal intensive care unit with gestational age of<35 weeks were included. Exclusion criteria were parental reluctance and requirement of phototherapy in the last 12 hours. Measurements were obtained through a smartphone application (BiliScan) along with simultaneous transcutaneous device (Dräger JM 105) and venous blood biochemistry.
    Results: Mean gestational age was 30.8±2.4 weeks and birth weight was 1622±566 g. Measurements were obtained at a median of 4 (1-21) days of life. Twenty-five infants (19.4%) had ABO and/or Rh incompatibility and 39 infants (30.2%) required phototherapy. None of the cases required exchange transfusion. Mean total serum bilirubin (TSB) level was 8.16±2.60 mg/dL, mean transcutaneous bilirubin (TcB) level was 8.60±2.70 mg/dL, and the mean bilirubin level measured by BiliScan was 7.26±2.68 mg/dL. For TSB and TcB measurements, the intraclass correlation coefficient (ICC) was found to be 0.915 (95% confidence interval 0.835-0.951; p<0.001) and a strong positive correlation was found between these two measurements. When TSB and BiliScan measurements were compared, ICC was found to be significant as 0.512 (95% confidence interval 0.353-0.638; p<0.001), with a moderate correlation.
    Conclusions: In this study, we evaluated the feasibility and reliability of a smartphone application for monitoring bilirubin levels in preterm infants. Although BiliScan measurements reported to display high correlation in term infants, a moderate correlation was found in the preterm infants. It is an emerging low-cost, non-invasive alternative for neonatal jaundice monitoring, however, results should be interpreted with caution in preterm infants.
    MeSH term(s) Infant, Newborn ; Humans ; Infant ; Infant, Premature ; Skin ; Reproducibility of Results ; Smartphone ; Bilirubin ; Jaundice, Neonatal/diagnosis ; Jaundice, Neonatal/therapy ; Neonatal Screening/methods
    Chemical Substances Bilirubin (RFM9X3LJ49)
    Language English
    Publishing date 2022-12-20
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 120650-3
    ISSN 1439-3824 ; 0300-8630
    ISSN (online) 1439-3824
    ISSN 0300-8630
    DOI 10.1055/a-1816-5878
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Dedifferentiated Liposarcoma of the Left Thigh: a Rare Case.

    Sengul, Demet / Sengul, Ilker / Ustun, Huseyin

    Medical archives (Sarajevo, Bosnia and Herzegovina)

    2019  Volume 73, Issue 2, Page(s) 121–122

    Abstract: Introduction: Liposarcoma is generally classified into four subtypes: a) well-differentiated liposarcoma/atypical lipomatous tumor, b) dedifferentiated liposarcoma, c) myxoid/round cell liposarcoma, and d) pleomorphic liposarcoma. Dedifferentiated ... ...

    Abstract Introduction: Liposarcoma is generally classified into four subtypes: a) well-differentiated liposarcoma/atypical lipomatous tumor, b) dedifferentiated liposarcoma, c) myxoid/round cell liposarcoma, and d) pleomorphic liposarcoma. Dedifferentiated liposarcoma is mostly seen in the region of retroperitoneum.
    Aim: To present a case of dedifferentiated liposarcoma in a rare site of location: the lower extremity.
    Case report: A 24-year-old woman presented with a firm painful mass, 3x2 cm in diameter on the medial side of left thigh. MRI demonstrated a lesion on that location showing low signal intensity on T1-wieghted and high signal intensity on T2A-wieghted sequences. After an excisional biopsy the histopathological examination via Haematoxylin and Eosin firstly revealed the diagnosis of malign undifferentiated tumor. The results of immunohistochemical evaluations were as follows: SMA (-), HMB45 (-), S100 (+, focally), Desmin (-), Vimentin (+, focally), CD68 (+, focally), CD34 (-), LCA (-), and Inhibin (-). The final histopathological diagnosis was dedifferentiated liposarcoma.
    Conclusions: In English-language literature data for dedifferentiated liposarcoma of the lower extremities are very restricted. Although imaging with CT and MRI, the final and distinct diagnosis is made immunohistochemically. A clinician should be aware of the presence of a dedifferentiated liposarcoma within a mass on the lower extremities.
    MeSH term(s) Female ; Humans ; Liposarcoma/diagnosis ; Liposarcoma/pathology ; Subcutaneous Tissue ; Thigh ; Young Adult
    Language English
    Publishing date 2019-08-08
    Publishing country Bosnia and Herzegovina
    Document type Case Reports
    ZDB-ID 128782-5
    ISSN 1986-5961 ; 0025-8083 ; 0350-199X
    ISSN (online) 1986-5961
    ISSN 0025-8083 ; 0350-199X
    DOI 10.5455/medarh.2019.73.121.122
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Eccrine Syringofibroadenomatosis of the Soles.

    Polat, Muhterem / Üstün, Hüseyin

    Journal of the American Podiatric Medical Association

    2016  Volume 106, Issue 2, Page(s) 141–143

    Abstract: Eccrine syringofibroadenoma is a rare adnexal tumor with acrosyringeal differentiation. It was first described by Mascaro in 1963. Its clinical presentation varies from a solitary nodule, keratotic papule, verrucous plaque, or palmoplantar keratoderma to ...

    Abstract Eccrine syringofibroadenoma is a rare adnexal tumor with acrosyringeal differentiation. It was first described by Mascaro in 1963. Its clinical presentation varies from a solitary nodule, keratotic papule, verrucous plaque, or palmoplantar keratoderma to multiple lesions with linear or diffuse distributions. Age at onset ranges from 16 to 80 years. Lesion distribution is wide and includes the face, back, abdomen, buttocks, extremities, and, rarely, nails. There are five subtypes of eccrine syringofibroadenoma. Histologically, eccrine syringofibroadenoma, independent of the subtype, is characterized by anastomosing cords of acrosyringeal cells forming ductal structures in a fibrovascular stroma and attached to the undersurface of the epidermis in multiple foci. In this article, we describe a 51-year-old woman diagnosed as having eccrine syringofibroadenomatosis.
    MeSH term(s) Adenoma, Sweat Gland/diagnosis ; Biopsy ; Diagnosis, Differential ; Female ; Foot ; Humans ; Middle Aged ; Skin/pathology ; Sweat Gland Neoplasms/diagnosis
    Language English
    Publishing date 2016-03
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 632622-5
    ISSN 1930-8264 ; 0003-0538 ; 8750-7315
    ISSN (online) 1930-8264
    ISSN 0003-0538 ; 8750-7315
    DOI 10.7547/14-163
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: A case of mesotherapy-induced panniculitis.

    Polat, Muhterem / Üstün, Hüseyin

    Cutaneous and ocular toxicology

    2016  Volume 35, Issue 2, Page(s) 163–164

    Abstract: Mesotherapy was first introduced in Europe for the treatment of localized pain. It is currently used mainly for aesthetical purposes and gradually getting widely used for body contouring, cellulite reduction, and skin rejuvenation. The reports concerning ...

    Abstract Mesotherapy was first introduced in Europe for the treatment of localized pain. It is currently used mainly for aesthetical purposes and gradually getting widely used for body contouring, cellulite reduction, and skin rejuvenation. The reports concerning about mesotherapy is increasing in number in the literature. There are reported systemic and local side effects of mesotherapy. Panniculitis is a rare side effect of mesotherapy. In this article, we report a case of mesotherapy-induced panniculitis who responded to dapsone therapy.
    MeSH term(s) Adult ; Anti-Infective Agents/therapeutic use ; Dapsone/therapeutic use ; Female ; Humans ; Injections ; Mesotherapy/adverse effects ; Panniculitis/drug therapy ; Panniculitis/etiology
    Chemical Substances Anti-Infective Agents ; Dapsone (8W5C518302)
    Language English
    Publishing date 2016
    Publishing country England
    Document type Case Reports ; Journal Article
    ZDB-ID 605635-0
    ISSN 1556-9535 ; 1556-9527 ; 0731-3829
    ISSN (online) 1556-9535
    ISSN 1556-9527 ; 0731-3829
    DOI 10.3109/15569527.2015.1042110
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: [No title information]

    Ustun, Huseyin / Oncel, Mehmet Yekta / Kefeli, Melike / Akar, Melek / Engür, Defne

    Klinische Pädiatrie

    2022  Volume 235, Issue 05, Page(s) 265–269

    Abstract: Backround: Aim of the present study is to evaluate the feasibility and reliability of an smartphone application for monitore of bilirubin levels in preterm infants.: Methods: Preterm infants hospitalized in the ...

    Abstract Backround: Aim of the present study is to evaluate the feasibility and reliability of an smartphone application for monitore of bilirubin levels in preterm infants.
    Methods: Preterm infants hospitalized in the neonatal intensive care unit with gestational age of<35 weeks were included. Exclusion criteria were parental reluctance and requirement of phototherapy in the last 12 hours. Measurements were obtained through a smartphone application (BiliScan) along with simultaneous transcutaneous device (Dräger JM 105) and venous blood biochemistry.
    Results: Mean gestational age was 30.8±2.4 weeks and birth weight was 1622±566 g. Measurements were obtained at a median of 4 (1–21) days of life. Twenty-five infants (19.4%) had ABO and/or Rh incompatibility and 39 infants (30.2%) required phototherapy. None of the cases required exchange transfusion. Mean total serum bilirubin (TSB) level was 8.16±2.60 mg/dL, mean transcutaneous bilirubin (TcB) level was 8.60±2.70 mg/dL, and the mean bilirubin level measured by BiliScan was 7.26±2.68 mg/dL. For TSB and TcB measurements, the intraclass correlation coefficient (ICC) was found to be 0.915 (95% confidence interval 0.835–0.951; p<0.001) and a strong positive correlation was found between these two measurements. When TSB and BiliScan measurements were compared, ICC was found to be significant as 0.512 (95% confidence interval 0.353–0.638; p<0.001), with a moderate correlation.
    Conclusions: In this study, we evaluated the feasibility and reliability of a smartphone application for monitoring bilirubin levels in preterm infants. Although BiliScan measurements reported to display high correlation in term infants, a moderate correlation was found in the preterm infants. It is an emerging low-cost, non-invasive alternative for neonatal jaundice monitoring, however, results should be interpreted with caution in preterm infants.
    Keywords Smartphone app ; premature ; jaundice ; hyperbilirubinemia ; BiliScan ; Smartphone-App ; Frühgeburt ; Gelbsucht ; Hyperbilirubinämie ; BiliScan
    Language English
    Publishing date 2022-12-20
    Publisher Georg Thieme Verlag
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 120650-3
    ISSN 1439-3824 ; 0300-8630
    ISSN (online) 1439-3824
    ISSN 0300-8630
    DOI 10.1055/a-1816-5878
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  7. Article: Truncal Erythema Elevatum Diutinum With Elevated Cryoglobulin Level.

    Ataş, Hatice / Eskioğlu, Fatma / Üstün, Hüseyin / Gönül, Müzeyyen

    Archives of rheumatology

    2017  Volume 32, Issue 4, Page(s) 370–372

    Language English
    Publishing date 2017-03-09
    Publishing country Turkey
    Document type Journal Article
    ZDB-ID 3012972-2
    ISSN 2618-6500 ; 2148-5046
    ISSN (online) 2618-6500
    ISSN 2148-5046
    DOI 10.5606/ArchRheumatol.2017.6355
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Topiramate as a neuroprotective agent in a rat model of spinal cord injury.

    Narin, Firat / Hanalioglu, Sahin / Ustun, Huseyin / Kilinc, Kamer / Bilginer, Burcak

    Neural regeneration research

    2018  Volume 12, Issue 12, Page(s) 2071–2076

    Abstract: Topiramate (TPM) is a widely used antiepileptic and antimigraine agent which has been shown to exert neuroprotective effects in various experimental traumatic brain injury and stroke models. However, its utility in spinal cord injury has not been studied ...

    Abstract Topiramate (TPM) is a widely used antiepileptic and antimigraine agent which has been shown to exert neuroprotective effects in various experimental traumatic brain injury and stroke models. However, its utility in spinal cord injury has not been studied extensively. Thus, we evaluated effects of TPM on secondary cellular injury mechanisms in an experimental rat model of traumatic spinal cord injury (SCI). After rat models of thoracic contusive SCI were established by free weight-drop method, TPM (40 mg/kg) was given at 12-hour intervals for four times orally. Post TPM treatment, malondialdehyde and protein carbonyl levels were significantly reduced and reduced glutathione levels were increased, while immunoreactivity for endothelial nitric oxide synthase, inducible nitric oxide synthase, and apoptotic peptidase activating factor 1 was diminished in SCI rats. In addition, TPM treatment improved the functional recovery of SCI rats. This study suggests that administration of TPM exerts neuroprotective effects on SCI.
    Language English
    Publishing date 2018-01-11
    Publishing country India
    Document type Journal Article
    ZDB-ID 2388460-5
    ISSN 1876-7958 ; 1673-5374
    ISSN (online) 1876-7958
    ISSN 1673-5374
    DOI 10.4103/1673-5374.221164
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  9. Article ; Online: Comparison of Conjunctival Cytological Alterations following Conventional and Sutureless Sclerotomies.

    Citirik, Mehmet / Altunkaya, Canan / Soba, Dilek / Bicer, Tolga / Ustun, Huseyin

    Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde

    2015  Volume 233, Issue 3-4, Page(s) 230–235

    Abstract: Purpose: To assess the alterations in conjunctival impression cytology following 23-gauge transconjunctival sutureless versus conventional pars plana vitrectomy.: Patients and methods: Sixty consecutive patients were enrolled in the study. ... ...

    Abstract Purpose: To assess the alterations in conjunctival impression cytology following 23-gauge transconjunctival sutureless versus conventional pars plana vitrectomy.
    Patients and methods: Sixty consecutive patients were enrolled in the study. Conjunctival impression cytology was performed on 30 eyes (of 30 subjects) with 23-gauge transconjunctival sutureless vitrectomy and on 30 eyes (of 30 subjects) with conventional vitrectomy. Conjunctival impression cytology was performed preoperatively on the 1st day and in the 3rd month after the surgery. Impression cytology specimens of each group were graded and scored using a range of 0-3 according to Nelson's method.
    Results: In the conventional pars plana vitrectomy group, statistically significant alterations in the conjunctival impression cytology were detected on the 1st postoperative day (p = 0.001) and in the 3rd postoperative month (p = 0.001), whereas in the 23-gauge transconjunctival sutureless pars plana vitrectomy group, statistically significant changes were observed on the 1st postoperative day. However, no significant changes were observed in the following 3 postoperative months (p = 0.08).
    Conclusion: The properties of impression cytology were altered in the early postoperative period after sutureless and conventional vitrectomy. These changes were improved in the sutureless vitrectomy group only. Sutureless vitrectomy also had an advantageous effect on the conjunctival cytological changes and conjunctival structure.
    MeSH term(s) Adult ; Aged ; Biopsy ; Cell Count ; Conjunctiva/pathology ; Conjunctival Diseases/diagnosis ; Conjunctival Diseases/etiology ; Conjunctival Diseases/surgery ; Epithelial Cells/pathology ; Female ; Humans ; Male ; Middle Aged ; Prospective Studies ; Retinal Diseases/surgery ; Sclera/surgery ; Sclerostomy/adverse effects ; Sclerostomy/methods ; Suture Techniques ; Vitrectomy ; Vitreous Hemorrhage/surgery ; Young Adult
    Language English
    Publishing date 2015
    Publishing country Switzerland
    Document type Comparative Study ; Journal Article
    ZDB-ID 209735-7
    ISSN 1423-0267 ; 0030-3755
    ISSN (online) 1423-0267
    ISSN 0030-3755
    DOI 10.1159/000371771
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  10. Article: Conjunctival impression cytology in non-proliferative and proliferative diabetic retinopathy.

    Citirik, Mehmet / Berker, Nilufer / Haksever, Hulya / Elgin, Ufuk / Ustun, Huseyin

    International journal of ophthalmology

    2014  Volume 7, Issue 2, Page(s) 321–325

    Abstract: Aim: To examine the integrity of the ocular surfaces of subjects with and without diabetes with no conjunctival and dry eye signs and symptoms and compare conjunctival impression cytology findings in diabetics with non-proliferative and proliferative ... ...

    Abstract Aim: To examine the integrity of the ocular surfaces of subjects with and without diabetes with no conjunctival and dry eye signs and symptoms and compare conjunctival impression cytology findings in diabetics with non-proliferative and proliferative diabetic retinopathy.
    Methods: Conjunctival impression cytology was performed on 43 eyes of 43 subjects with non-proliferative diabetic retinopathy (NPDR), 42 eyes of 42 subjects with proliferative diabetic retinopathy (PDR), and 30 eyes of 30 control subjects. Impression cytology specimens of each group were graded and scored in the range 0-3 according to Nelson's method.
    Results: There were 45 (52.9%) women and 40 (47.1%) men. The mean age of the patients was 59.6±9.3y (range, 43-76y) in NPDR group and 58.0±8.8y (range, 41-85y) in PDR group. Cases with NPDR and PDR showed statistically significant higher impression cytology scores than control group (P<0.05). There was no difference between the NPDR and PDR patients for impression cytology grading scores.
    Conclusion: It is determined that impression cytology grades are altered in patients with NPDR and PDR. Consequently, we suggest that there might be an association between the impression cytology grading scores and the severity of diabetic retinopathy.
    Language English
    Publishing date 2014-04-18
    Publishing country China
    Document type Journal Article
    ZDB-ID 2663246-9
    ISSN 2227-4898 ; 2222-3959
    ISSN (online) 2227-4898
    ISSN 2222-3959
    DOI 10.3980/j.issn.2222-3959.2014.02.23
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