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  1. Article ; Online: Comprehensive insight into triclosan—from widespread occurrence to health outcomes

    Milanović, Maja / Đurić, Larisa / Milošević, Nataša / Milić, Nataša

    Environ Sci Pollut Res. 2023 Feb., v. 30, no. 10 p.25119-25140

    2023  

    Abstract: Humans are exposed to the variety of emerging environmental pollutant in everyday life. The special concern is paid to endocrine disrupting chemicals especially to triclosan which could interfere with normal hormonal functions. Triclosan could be found ... ...

    Abstract Humans are exposed to the variety of emerging environmental pollutant in everyday life. The special concern is paid to endocrine disrupting chemicals especially to triclosan which could interfere with normal hormonal functions. Triclosan could be found in numerous commercial products such as mouthwashes, toothpastes and disinfectants due to its antibacterial and antifungal effects. Considering the excessive use and disposal, wastewaters are recognized as the main source of triclosan in the aquatic environment. As a result of the incomplete removal, triclosan residues reach surface water and even groundwater. Triclosan has potential to accumulate in sediment and aquatic organisms. Therefore, the detectable concentrations of triclosan in various environmental and biological matrices emerged concerns about the potential toxicity. Triclosan impairs thyroid homeostasis and could be associated with neurodevelopment impairment, metabolic disorders, cardiotoxicity and the increased cancer risk. The growing resistance of the vast groups of bacteria, the evidenced toxicity on different aquatic organisms, its adverse health effects observed in vitro, in vivo as well as the available epidemiological studies suggest that further efforts to monitor triclosan toxicity at environmental levels are necessary. The safety precaution measures and full commitment to proper legislation in compliance with the environmental protection are needed in order to obtain triclosan good ecological status. This paper is an overview of the possible negative triclosan effects on human health. Sources of exposure to triclosan, methods and levels of detection in aquatic environment are also discussed.
    Keywords aquatic environment ; cardiotoxicity ; compliance ; environmental protection ; groundwater ; homeostasis ; human health ; laws and regulations ; neurodevelopment ; pollutants ; risk ; sediments ; surface water ; toxicity ; triclosan ; wastewater
    Language English
    Dates of publication 2023-02
    Size p. 25119-25140.
    Publishing place Springer Berlin Heidelberg
    Document type Article ; Online
    Note Review
    ZDB-ID 1178791-0
    ISSN 1614-7499 ; 0944-1344
    ISSN (online) 1614-7499
    ISSN 0944-1344
    DOI 10.1007/s11356-021-17273-0
    Database NAL-Catalogue (AGRICOLA)

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  2. Article ; Online: Comprehensive insight into triclosan-from widespread occurrence to health outcomes.

    Milanović, Maja / Đurić, Larisa / Milošević, Nataša / Milić, Nataša

    Environmental science and pollution research international

    2021  Volume 30, Issue 10, Page(s) 25119–25140

    Abstract: Humans are exposed to the variety of emerging environmental pollutant in everyday life. The special concern is paid to endocrine disrupting chemicals especially to triclosan which could interfere with normal hormonal functions. Triclosan could be found ... ...

    Abstract Humans are exposed to the variety of emerging environmental pollutant in everyday life. The special concern is paid to endocrine disrupting chemicals especially to triclosan which could interfere with normal hormonal functions. Triclosan could be found in numerous commercial products such as mouthwashes, toothpastes and disinfectants due to its antibacterial and antifungal effects. Considering the excessive use and disposal, wastewaters are recognized as the main source of triclosan in the aquatic environment. As a result of the incomplete removal, triclosan residues reach surface water and even groundwater. Triclosan has potential to accumulate in sediment and aquatic organisms. Therefore, the detectable concentrations of triclosan in various environmental and biological matrices emerged concerns about the potential toxicity. Triclosan impairs thyroid homeostasis and could be associated with neurodevelopment impairment, metabolic disorders, cardiotoxicity and the increased cancer risk. The growing resistance of the vast groups of bacteria, the evidenced toxicity on different aquatic organisms, its adverse health effects observed in vitro, in vivo as well as the available epidemiological studies suggest that further efforts to monitor triclosan toxicity at environmental levels are necessary. The safety precaution measures and full commitment to proper legislation in compliance with the environmental protection are needed in order to obtain triclosan good ecological status. This paper is an overview of the possible negative triclosan effects on human health. Sources of exposure to triclosan, methods and levels of detection in aquatic environment are also discussed.
    MeSH term(s) Humans ; Triclosan/analysis ; Risk ; Disinfectants/pharmacology ; Antifungal Agents/pharmacology ; Aquatic Organisms ; Outcome Assessment, Health Care ; Water Pollutants, Chemical/analysis
    Chemical Substances Triclosan (4NM5039Y5X) ; Disinfectants ; Antifungal Agents ; Water Pollutants, Chemical
    Language English
    Publishing date 2021-11-06
    Publishing country Germany
    Document type Journal Article ; Review
    ZDB-ID 1178791-0
    ISSN 1614-7499 ; 0944-1344
    ISSN (online) 1614-7499
    ISSN 0944-1344
    DOI 10.1007/s11356-021-17273-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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