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Book ; Online: Persistent Organic Pollutants in Human Milk

Malisch, Rainer / Fürst, Peter / Šebková, Kateřina

2023

Author's details	edited by Rainer Malisch, Peter Fürst, Kateřina Šebková
Keywords	Environmental chemistry ; Analytical chemistry ; Toxicology ; Gynecology ; Nutrition ; Environment
Language	English
Size	1 Online-Ressource (XXVII, 683 p. 318 illus., 309 illus. in color)
Edition	1st ed. 2023
Publisher	Springer International Publishing ; Imprint: Springer
Publishing place	Cham
Document type	Book ; Online
HBZ-ID	HT030390234
ISBN	978-3-031-34087-1 ; 9783031340857 ; 9783031340864 ; 3-031-34087-6 ; 303134085X ; 3031340868
DOI	10.1007/978-3-031-34087-1
Database	ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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Book ; Online: Persistent Organic Pollutants in Human Milk

Malisch, Rainer / Fürst, Peter / Šebková, Kateřina / Šebková, Kateřina

2023

Keywords	Pollution & threats to the environment ; Analytical chemistry ; Pharmacology ; Biochemistry ; The environment ; Persistent organic pollutants ; Biomonitoring Human Milk ; Contaminants in Human Milk ; Chlorinated Paraffins ; Chlorinated Pesticides ; Human health risks ; Maternal and Child Health ; Polybrominated and Perfluoroalkane substances ; Polychlorinated biphenyls ; Polychlorinated dibenzofurans ; Polychlorinated dibenzo-p-dioxins ; Polychlorinated naphtalenes ; United Nations Environment Programme ; WHO/UNEP-coordinated global survey of human milk ; World Health Organization
Language	English
Size	1 electronic resource (683 pages)
Publisher	Springer Nature
Publishing place	Cham
Document type	Book ; Online
Note	English
HBZ-ID	HT030612772
ISBN	9783031340857 ; 303134085X
Database	ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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Article ; Online: Persistent Problem: Global Challenges to Managing PCBs.

Melymuk, Lisa / Blumenthal, Jonathan / Sáňka, Ondřej / Shu-Yin, Adriana / Singla, Veena / Šebková, Kateřina / Pullen Fedinick, Kristi / Diamond, Miriam L

Environmental science & technology

2022 Volume 56, Issue 12, Page(s) 9029–9040

Abstract: Polychlorinated biphenyls (PCBs), "famous" as persistent organic pollutants (POPs), have been managed nationally since the 1970s and globally under the Stockholm Convention on POPs since 2004, requiring environmentally sound management (ESM) of PCBs by ... ...

Abstract	Polychlorinated biphenyls (PCBs), "famous" as persistent organic pollutants (POPs), have been managed nationally since the 1970s and globally under the Stockholm Convention on POPs since 2004, requiring environmentally sound management (ESM) of PCBs by 2028. At most, 30% of countries are on track to achieve ESM by 2028. Globally over 10 million tonnes of PCB-containing materials remain, mostly in countries lacking the ability to manage PCB waste. Canada (Ontario) and Czechia, both parties to the Stockholm Convention, are close to achieving the 2028 goal, having reduced their stocks of pure PCBs by 99% in the past 10 years. In contrast, the USA, not a party to the Stockholm Convention, continues to have a substantial but poorly inventoried stock of PCBs and only ∼3% decrease in mass of PCBs since 2006. PCB management, which depends on Stockholm Convention support and national compliance, portends major challenges for POP management. The failure to manage global PCB stocks >30 years after the end of production highlights the urgent need to prioritize reducing production and use of newer, more widely distributed POPs such as chlorinated paraffins and per- and polyfluorinated alkyl substances, as these management challenges are unlikely to be resolved in the coming decades.
MeSH term(s)	Environmental Monitoring ; Environmental Pollutants/analysis ; Ontario ; Paraffin ; Polychlorinated Biphenyls/analysis
Chemical Substances	Environmental Pollutants ; Paraffin (8002-74-2) ; Polychlorinated Biphenyls (DFC2HB4I0K)
Language	English
Publishing date	2022-06-01
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ISSN	1520-5851
ISSN (online)	1520-5851
DOI	10.1021/acs.est.2c01204
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Persistent Problem: Global Challenges to Managing PCBs

Melymuk, Lisa / Blumenthal, Jonathan / Sáňka, Ondřej / Shu-Yin, Adriana / Singla, Veena / Šebková, Kateřina / Pullen Fedinick, Kristi / Diamond, Miriam L.

Environmental science & technology. 2022 June 01, v. 56, no. 12

2022

Abstract: Polychlorinated biphenyls (PCBs), “famous” as persistent organic pollutants (POPs), have been managed nationally since the 1970s and globally under the Stockholm Convention on POPs since 2004, requiring environmentally sound management (ESM) of PCBs by ... ...

Abstract	Polychlorinated biphenyls (PCBs), “famous” as persistent organic pollutants (POPs), have been managed nationally since the 1970s and globally under the Stockholm Convention on POPs since 2004, requiring environmentally sound management (ESM) of PCBs by 2028. At most, 30% of countries are on track to achieve ESM by 2028. Globally over 10 million tonnes of PCB-containing materials remain, mostly in countries lacking the ability to manage PCB waste. Canada (Ontario) and Czechia, both parties to the Stockholm Convention, are close to achieving the 2028 goal, having reduced their stocks of pure PCBs by 99% in the past 10 years. In contrast, the USA, not a party to the Stockholm Convention, continues to have a substantial but poorly inventoried stock of PCBs and only ∼3% decrease in mass of PCBs since 2006. PCB management, which depends on Stockholm Convention support and national compliance, portends major challenges for POP management. The failure to manage global PCB stocks >30 years after the end of production highlights the urgent need to prioritize reducing production and use of newer, more widely distributed POPs such as chlorinated paraffins and per- and polyfluorinated alkyl substances, as these management challenges are unlikely to be resolved in the coming decades.
Keywords	compliance ; polychlorinated biphenyls ; technology ; wastes ; Czech Republic ; Ontario
Language	English
Dates of publication	2022-0601
Size	p. 9029-9040.
Publishing place	American Chemical Society
Document type	Article
ISSN	1520-5851
DOI	10.1021/acs.est.2c01204
Database	NAL-Catalogue (AGRICOLA)

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Article: The science-policy interfaces of the European network for observing our changing planet: From Earth Observation data to policy-oriented decisions

Pirrone, Nicola / Mazzetti, Paolo / Cinnirella, Sergio / Athanasopoulou, Eleni / Gerasopoulos, Evangelos / Klánová, Jana / Lehmann, Anthony / Pau, Joan Masó / Petäjä, Tuukka / Pokorný, Lukáš / Šebková, Kateřina

Environmental science & policy. 2022 Nov., v. 137

2022

Abstract: This paper reports on major outcomes of the ERA-PLANET (The European network for observing our changing planet) project, which was funded under Horizon 2020 ERA-net co-funding scheme. ERA-PLANET strengthened the European Research Area in the domain of ... ...

Abstract	This paper reports on major outcomes of the ERA-PLANET (The European network for observing our changing planet) project, which was funded under Horizon 2020 ERA-net co-funding scheme. ERA-PLANET strengthened the European Research Area in the domain of Earth Observation (EO) in coherence with the European participation to Group on Earth Observation and the Copernicus European Union’s Earth Observation programme. ERA-PLANET was implemented through four projects focused on smart cities and resilient societies (SMURBS), resource efficiency and environmental management (GEOEssential), global changes and environmental treaties (iGOSP) and polar areas and natural resources (iCUPE). These projects developed specific science-policy workflows and interfaces to address selected environmental policy issues and design cost-effective strategies aiming to achieve targeted objectives. Key Enabling Technologies were implemented to enhancing ‘data to knowledge’ transition for supporting environmental policy making. Data cube technologies, the Virtual Earth Laboratory, Earth Observation ontologies and Knowledge Platforms were developed and used for such applications. SMURBS brought a substantial contribution to resilient cities and human settlements topics that were adopted by GEO as its 4th engagement priority, bringing the urban resilience topic in the GEO agenda on par with climate change, sustainable development and disaster risk reduction linked to environmental policies. GEOEssential is contributing to the development of Essential Variables (EVs) concept, which is encouraging and should allow the EO community to complete the description of the Earth System with EVs in a close future. This will clearly improve our capacity to address intertwined environmental and development policies as a Nexus. iGOSP supports the implementation of the GEO Flagship on Mercury (GOS⁴M) and the GEO Initiative on POPs (GOS⁴POPs) by developing a new integrated approach for global real-time monitoring of environmental quality with respect to air, water and human matrices contamination by toxic substances, like mercury and persistent organic pollutants. iGOSP developed end-user-oriented Knowledge Hubs that provide data repository systems integrated with data management consoles and knowledge information systems. The main outcomes from iCUPE are the novel and comprehensive data sets and a modelling activity that contributed to delivering science-based insights for the Arctic region. Applications enable defining and monitoring of Arctic Essential Variables and sets up processes towards UN2030 SDGs that include health (SDG 3), clean water resources and sanitation (SDGs 6 and 14).
Keywords	European Union ; air ; climate change ; cost effectiveness ; environmental management ; environmental policy ; environmental quality ; humans ; information management ; mercury ; risk reduction ; sanitation ; sustainable development ; toxicity ; Arctic region
Language	English
Dates of publication	2022-11
Size	p. 359-372.
Publishing place	Elsevier Ltd
Document type	Article
ZDB-ID	1454687-5
ISSN	1462-9011
ISSN	1462-9011
DOI	10.1016/j.envsci.2022.09.006
Database	NAL-Catalogue (AGRICOLA)

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Article: Implementation of the Minamata Convention to manage mercury pollution in India: challenges and opportunities

Sharma, Brij Mohan / Bharat, Girija K / Scheringer, Martin / Šebková, Kateřina

Environmental sciences Europe. 2019 Dec., v. 31, no. 1

2019

Abstract: The Minamata Convention (MC), a multilateral environmental agreement (MEA), aims to protect human health and the environment from anthropogenic emissions and releases of mercury and its compounds. The success of the MC essentially depends on its ... ...

Abstract	The Minamata Convention (MC), a multilateral environmental agreement (MEA), aims to protect human health and the environment from anthropogenic emissions and releases of mercury and its compounds. The success of the MC essentially depends on its effective implementation in developing regions especially those where the contribution to global mercury emissions is large. We assess the challenges and opportunities that lie ahead of the MC’s implementation in India, which is among the top mercury emitters in the world. We examine the influence of existing Indian regulations on several aspects of the MC and highlight those areas that should be prioritized in future actions combating mercury pollution in India. India has elaborate regulations on several important aspects of the MC, yet their implementation and enforcement remain weak. To change the current situation, it is necessary to develop programs that systematically track mercury consumption, within-country trade, and emissions, monitor environment and human exposure to mercury, and reconcile the mercury management agenda and actions with national development plans in India. India needs to prepare, and timely provide to the secretariat of the convention, the National Action Plan (NAP) with a special focus on managing mercury emissions and releases as described in the Articles 8 and 9 of the MC. Overall, effectively implementing the MC in India will result not only in curbing mercury pollution, but also help in progress towards related Sustainable Development Goals.
Keywords	emissions ; human health ; mercury ; pollution ; sustainable development ; trade ; India
Language	English
Dates of publication	2019-12
Size	p. 96.
Publishing place	Springer Berlin Heidelberg
Document type	Article
ZDB-ID	2593962-2
ISSN	2190-4715 ; 2190-4707
ISSN (online)	2190-4715
ISSN	2190-4707
DOI	10.1186/s12302-019-0280-3
Database	NAL-Catalogue (AGRICOLA)

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Article: The COVID-19 pandemic and global environmental change: Emerging research needs

Barouki, Robert / Kogevinas, Manolis / Audouze, Karine / Belesova, Kristine / Bergman, Ake / Birnbaum, Linda / Boekhold, Sandra / Denys, Sebastien / Desseille, Celine / Drakvik, Elina / Frumkin, Howard / Garric, Jeanne / Destoumieux-Garzon, Delphine / Haines, Andrew / Huss, Anke / Jensen, Genon / Karakitsios, Spyros / Klanova, Jana / Koskela, Iida-Maria /

Laden, Francine / Marano, Francelyne / Franziska Matthies-Wiesler, Eva / Morris, George / Nowacki, Julia / Paloniemi, Riikka / Pearce, Neil / Peters, Annette / Rekola, Aino / Sarigiannis, Denis / Šebková, Katerina / Slama, Remy / Staatsen, Brigit / Tonne, Cathryn / Vermeulen, Roel / Vineis, Paolo

Environment international. 2021 Jan., v. 146

2021

Abstract: The outbreak of COVID-19 raised numerous questions on the interactions between the occurrence of new infections, the environment, climate and health. The European Union requested the H2020 HERA project which aims at setting priorities in research on ... ...

Institution	The HERA-COVID-19 working group
Abstract	The outbreak of COVID-19 raised numerous questions on the interactions between the occurrence of new infections, the environment, climate and health. The European Union requested the H2020 HERA project which aims at setting priorities in research on environment, climate and health, to identify relevant research needs regarding Covid-19. The emergence and spread of SARS-CoV-2 appears to be related to urbanization, habitat destruction, live animal trade, intensive livestock farming and global travel. The contribution of climate and air pollution requires additional studies. Importantly, the severity of COVID-19 depends on the interactions between the viral infection, ageing and chronic diseases such as metabolic, respiratory and cardiovascular diseases and obesity which are themselves influenced by environmental stressors. The mechanisms of these interactions deserve additional scrutiny. Both the pandemic and the social response to the disease have elicited an array of behavioural and societal changes that may remain long after the pandemic and that may have long term health effects including on mental health. Recovery plans are currently being discussed or implemented and the environmental and health impacts of those plans are not clearly foreseen. Clearly, COVID-19 will have a long-lasting impact on the environmental health field and will open new research perspectives and policy needs.
Keywords	COVID-19 infection ; European Union ; Severe acute respiratory syndrome coronavirus 2 ; air pollution ; climate ; environment ; environmental health ; global change ; habitat destruction ; issues and policy ; livestock ; mental health ; obesity ; pandemic ; trade ; travel ; urbanization
Language	English
Dates of publication	2021-01
Publishing place	Elsevier Ltd
Document type	Article
ZDB-ID	554791-x
ISSN	1873-6750 ; 0160-4120
ISSN (online)	1873-6750
ISSN	0160-4120
DOI	10.1016/j.envint.2020.106272
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: GEI-8, a homologue of vertebrate nuclear receptor corepressor NCoR/SMRT, regulates gonad development and neuronal functions in Caenorhabditis elegans.

Mikoláš, Pavol / Kollárová, Johana / Sebková, Kateřina / Saudek, Vladimír / Yilma, Petr / Kostrouchová, Markéta / Krause, Michael W / Kostrouch, Zdenek / Kostrouchová, Marta

PloS one

2013 Volume 8, Issue 3, Page(s) e58462

Abstract: NCoR and SMRT are two paralogous vertebrate proteins that function as corepressors with unliganded nuclear receptors. Although C. elegans has a large number of nuclear receptors, orthologues of the corepressors NCoR and SMRT have not unambiguously been ... ...

Abstract	NCoR and SMRT are two paralogous vertebrate proteins that function as corepressors with unliganded nuclear receptors. Although C. elegans has a large number of nuclear receptors, orthologues of the corepressors NCoR and SMRT have not unambiguously been identified in Drosophila or C. elegans. Here, we identify GEI-8 as the closest homologue of NCoR and SMRT in C. elegans and demonstrate that GEI-8 is expressed as at least two isoforms throughout development in multiple tissues, including neurons, muscle and intestinal cells. We demonstrate that a homozygous deletion within the gei-8 coding region, which is predicted to encode a truncated protein lacking the predicted NR domain, results in severe mutant phenotypes with developmental defects, slow movement and growth, arrested gonadogenesis and defects in cholinergic neurotransmission. Whole genome expression analysis by microarrays identified sets of de-regulated genes consistent with both the observed mutant phenotypes and a role of GEI-8 in regulating transcription. Interestingly, the upregulated transcripts included a predicted mitochondrial sulfide:quinine reductase encoded by Y9C9A.16. This locus also contains non-coding, 21-U RNAs of the piRNA class. Inhibition of the expression of the region coding for 21-U RNAs leads to irregular gonadogenesis in the homozygous gei-8 mutants, but not in an otherwise wild-type background, suggesting that GEI-8 may function in concert with the 21-U RNAs to regulate gonadogenesis. Our results confirm that GEI-8 is the orthologue of the vertebrate NCoR/SMRT corepressors and demonstrate important roles for this putative transcriptional corepressor in development and neuronal function.
MeSH term(s)	Amino Acid Sequence ; Animals ; Base Sequence ; Caenorhabditis elegans/genetics ; Caenorhabditis elegans/physiology ; Caenorhabditis elegans Proteins/genetics ; Caenorhabditis elegans Proteins/metabolism ; Co-Repressor Proteins/genetics ; Co-Repressor Proteins/metabolism ; Gene Deletion ; Gene Expression Profiling ; Gene Expression Regulation/genetics ; Gonads/growth & development ; Microarray Analysis ; Molecular Sequence Data ; Neurons/physiology ; Nuclear Receptor Co-Repressor 1/genetics ; Nuclear Receptor Co-Repressor 2/genetics ; Receptors, Cytoplasmic and Nuclear/metabolism ; Sequence Alignment ; Sequence Analysis, DNA
Chemical Substances	Caenorhabditis elegans Proteins ; Co-Repressor Proteins ; GEI-8 protein, C elegans ; Nuclear Receptor Co-Repressor 1 ; Nuclear Receptor Co-Repressor 2 ; Receptors, Cytoplasmic and Nuclear
Language	English
Publishing date	2013-03-06
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ISSN	1932-6203
ISSN (online)	1932-6203
DOI	10.1371/journal.pone.0058462
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: The COVID-19 pandemic and global environmental change: Emerging research needs.

Environment international

2020 Volume 146, Page(s) 106272

Abstract	The outbreak of COVID-19 raised numerous questions on the interactions between the occurrence of new infections, the environment, climate and health. The European Union requested the H2020 HERA project which aims at setting priorities in research on environment, climate and health, to identify relevant research needs regarding Covid-19. The emergence and spread of SARS-CoV-2 appears to be related to urbanization, habitat destruction, live animal trade, intensive livestock farming and global travel. The contribution of climate and air pollution requires additional studies. Importantly, the severity of COVID-19 depends on the interactions between the viral infection, ageing and chronic diseases such as metabolic, respiratory and cardiovascular diseases and obesity which are themselves influenced by environmental stressors. The mechanisms of these interactions deserve additional scrutiny. Both the pandemic and the social response to the disease have elicited an array of behavioural and societal changes that may remain long after the pandemic and that may have long term health effects including on mental health. Recovery plans are currently being discussed or implemented and the environmental and health impacts of those plans are not clearly foreseen. Clearly, COVID-19 will have a long-lasting impact on the environmental health field and will open new research perspectives and policy needs.
MeSH term(s)	Air Pollution ; Animals ; COVID-19 ; Climate ; Humans ; Pandemics ; SARS-CoV-2
Language	English
Publishing date	2020-11-19
Publishing country	Netherlands
Document type	Journal Article ; Research Support, Non-U.S. Gov't ; Review
ZDB-ID	554791-x
ISSN	1873-6750 ; 0160-4120
ISSN (online)	1873-6750
ISSN	0160-4120
DOI	10.1016/j.envint.2020.106272
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Article ; Online: The COVID-19 pandemic and global environmental change: emerging research needs

Environ Int

Abstract	The outbreak of COVID-19 raised numerous questions on the interactions between the occurrence of new infections, the environment, climate and health. The European Union requested the H2020 HERA project which aims at setting priorities in research on environment, climate and health, to identify relevant research needs regarding Covid-19. The emergence and spread of SARS-CoV-2 appears to be related to urbanization, habitat destruction, live animal trade, intensive livestock farming and global travel. The contribution of climate and air pollution requires additional studies. Importantly, the severity of COVID-19 depends on the interactions between the viral infection, ageing and chronic diseases such as metabolic, respiratory and cardiovascular diseases and obesity which are themselves influenced by environmental stressors. The mechanisms of these interactions deserve additional scrutiny. Both the pandemic and the social response to the disease have elicited an array of behavioural and societal changes that may remain long after the pandemic and that may have long term health effects including on mental health. Recovery plans are currently being discussed or implemented and the environmental and health impacts of those plans are not clearly foreseen. Clearly, COVID-19 will have a long-lasting impact on the environmental health field and will open new research perspectives and policy needs.
Keywords	covid19
Publisher	Elsevier; PMC
Document type	Article ; Online
DOI	10.1016/j.envint.2020.106272
Database	COVID19

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