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  1. Article ; Online: Educating the educator in clinical and translational research

    Emma A. Meagher / Janice Gabrilove / Cecilia M. Patino-Sutton

    Journal of Clinical and Translational Science, Vol

    2022  Volume 6

    Keywords Medicine ; R
    Language English
    Publishing date 2022-01-01T00:00:00Z
    Publisher Cambridge University Press
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: Remembering the impact of our collective voice

    Emma A. Meagher

    Journal of Clinical and Translational Science, Vol 1, Pp 145-

    2017  Volume 145

    Keywords Medicine ; R
    Language English
    Publishing date 2017-06-01T00:00:00Z
    Publisher Cambridge University Press
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: Customized Career Development Platform (CCDP) for clinical and translational researchers

    Doris M. Rubio / Colleen Mayowski / Emma A. Meagher / Cecilia M. Patino / Maya S. Thakar / Julie L. Welch / Gretchen E. White

    Journal of Clinical and Translational Science, Vol

    A pragmatic cluster-randomized controlled trial

    2023  Volume 7

    Abstract: Abstract Introduction: Early-stage clinical and translational researchers who set and track career goals, milestones, and progress are successful in career development. We aimed to determine the effectiveness of the Customized Career Development Platform ...

    Abstract Abstract Introduction: Early-stage clinical and translational researchers who set and track career goals, milestones, and progress are successful in career development. We aimed to determine the effectiveness of the Customized Career Development Platform (CCDP), an online individual development plan (IDP), versus the traditional IDP template in improving research success and career satisfaction. Methods: We conducted a pragmatic cluster-randomized controlled trial of 340 scholars and trainees at 27 US academic healthcare institutions. The primary outcome was number of published manuscripts 24 months post-intervention. Secondary outcomes included the number of grant proposals submitted and funded, job satisfaction, and level of communication with mentors. An analysis of CCDP participants assessed proficiency level for the 14 Clinical and Translational Science Award (CTSA) competencies. Data were analyzed using intention-to-treat. Results: Participants were mostly female (60.3%) and Caucasian (67.2%); mean age was 34 years. Twenty-four months following the intervention, the CCDP versus traditional IDP groups showed a similar number of publications (9.4 vs 8.6), grants submitted (4.1 vs 4.4) and funded (1.3 vs 2.0), and job satisfaction score (3.6 vs 3.7). The CCDP group had higher odds of discussing communication (OR = 2.08) and leadership skills (OR = 2.62) and broadening their network (2.31) than the traditional IDP group. The CCDP arm reported improvements in 9 of the 14 CTSA competencies. Conclusion: The CCDP offers CTSA hubs an innovative alternative to traditional IDP tools. Future studies are needed to elucidate why the CCDP users did not fully appreciate or adopt the functionality of the online platform.
    Keywords Career development ; career planning ; individualized development plan ; career success ; career goals and milestones ; competencies ; mentoring ; Medicine ; R
    Subject code 300
    Language English
    Publishing date 2023-01-01T00:00:00Z
    Publisher Cambridge University Press
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article ; Online: A counterpoint to “training the translational workforce

    Paul R. Marantz / Marla J. Keller / Emma A. Meagher

    Journal of Clinical and Translational Science, Vol 4, Pp 363-

    expanding beyond translational research to include translational science”

    2020  Volume 364

    Keywords Discipline ; education ; training ; translational research ; translational science ; Medicine ; R
    Language English
    Publishing date 2020-08-01T00:00:00Z
    Publisher Cambridge University Press
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article ; Online: Continued impact of COVID-19 pandemic on clinical and translational science early-career researchers

    Colleen Mayowski / Emma A. Meagher / Andrew D. Althouse / Cecilia Patino-Sutton / Maya S. Thakar / Julie L. Welch / Doris M. Rubio / Gretchen E. White

    Journal of Clinical and Translational Science, Vol

    2023  Volume 7

    Abstract: The COVID-19 pandemic had an immediate impact on the lives and work of early-career researchers. We leveraged a cluster-randomized trial and compared survey data collected over two timepoints to explore whether these impacts persisted. Although more than ...

    Abstract The COVID-19 pandemic had an immediate impact on the lives and work of early-career researchers. We leveraged a cluster-randomized trial and compared survey data collected over two timepoints to explore whether these impacts persisted. Although more than a year had passed, 74% of participants reported that their research was affected in multiple ways in both 2020 and 2021. These data suggest that the effects of the pandemic on early-career researchers may be prolonged. Our findings additionally serve as an impetus to identify and implement solutions to early-career challenges that undoubtedly existed before the pandemic, but which COVID-19 brought into the spotlight.
    Keywords COVID-19 ; career development ; Medicine ; R
    Language English
    Publishing date 2023-01-01T00:00:00Z
    Publisher Cambridge University Press
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article ; Online: The role of mentors in addressing issues of work–life integration in an academic research environment

    Dennis R. Durbin / Stephanie C. House / Emma A. Meagher / Jenna Griebel Rogers

    Journal of Clinical and Translational Science, Vol 3, Pp 302-

    2019  Volume 307

    Abstract: AbstractIntroduction:There is growing evidence for both the need to manage work–life conflict and the opportunity for mentors to advise their mentees on how to do this in an academic research environment.Methods:A multiphase approach was used to develop ... ...

    Abstract AbstractIntroduction:There is growing evidence for both the need to manage work–life conflict and the opportunity for mentors to advise their mentees on how to do this in an academic research environment.Methods:A multiphase approach was used to develop and implement an evidence-informed training module to help mentors guide their mentees in issues of work–life conflict. Analysis of existing data from a randomized controlled trial (RCT) of a mentor training curriculum (n = 283 mentor/mentee dyads) informed the development of a work–life mentoring module which was incorporated into an established research mentor training curriculum and evaluated by faculty at a single academic medical center.Results:Only 39% of mentors and 36% of mentees in the RCT indicated high satisfaction with the balance between their personal and professional lives. The majority (75%) of mentors and mentees were sharing personal information as part of the mentoring relationship which was significantly associated with mentees’ ratings of the balance between their personal and professional lives. The effectiveness of the work–life module was assessed by 60 faculty mentors participating in a mentor training program at an academic medical center from 2013 to 2017. Among the respondents to the post-training survey, 82.5% indicated they were very/somewhat comfortable addressing work–life issues with their mentees as a result of the training, with significant improvements (p = 0.001) in self-assessments of mentoring skill in this domain.Conclusions:Our findings indicate that a structured training approach can significantly improve mentors’ self-reported skills in addressing work–life issues with their mentees.
    Keywords Mentoring ; academic medical center ; professional development ; mentor training ; work–life integration ; work–life conflict ; Medicine ; R
    Subject code 370
    Language English
    Publishing date 2019-12-01T00:00:00Z
    Publisher Cambridge University Press
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article ; Online: Certification of clinical and translational researchers

    Paul R. Marantz / Harry P. Selker / Emma A. Meagher

    Journal of Clinical and Translational Science, Vol 1, Pp 3-

    An ill-conceived notion

    2017  Volume 4

    Abstract: Abstract The National Board of Medical Examiners (NBME) has instituted a new multiple choice examination in order to “certify” clinical and translational investigators. As experienced research educators, we argue that this certification process is ... ...

    Abstract Abstract The National Board of Medical Examiners (NBME) has instituted a new multiple choice examination in order to “certify” clinical and translational investigators. As experienced research educators, we argue that this certification process is unnecessary, values knowledge over competency, may be counter-productive, and is unlikely to achieve any worthwhile outcome. We lay out these arguments in the hope of stimulating a robust discussion among leaders, faculty, and learners engaged in clinical research education and training.
    Keywords Medicine ; R
    Language English
    Publishing date 2017-02-01T00:00:00Z
    Publisher Cambridge University Press
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article ; Online: Creating effective career development programs

    Doris McGartland Rubio / Georgeanna F. W. B. Robinson / Janice Gabrilove / Emma A. Meagher

    Journal of Clinical and Translational Science, Vol 1, Pp 83-

    2017  Volume 87

    Abstract: Abstract This paper is the fourth in a 5-part series that focuses on educating and training the clinical and translational science workforce. The goal of this paper is to delineate components of effective career development programs that go beyond ... ...

    Abstract Abstract This paper is the fourth in a 5-part series that focuses on educating and training the clinical and translational science workforce. The goal of this paper is to delineate components of effective career development programs that go beyond didactic training. All academic health centers with a Clinical and Translational Science Award have a KL2 career development award for junior faculty, and many also have a TL1 training program for predoctoral and postdoctoral fellows. The training across these programs varies, however junior investigators across the United States experience similar challenges. Junior investigators can get overwhelmed with the demands of building their own research program, particularly in academia. 1Often, they are sidetracked by competing demands that can derail their progress. In these situations, junior investigators experience frustration and may search for alternative career paths. By providing them with additional professional skills in the 5 domains of: (1) self-awareness; (2) selecting the right topic and securing funding; (3) getting adequate support; (4) working with others; and (5) managing yourself, your career, and your demands. We will give junior investigators additional tools to manage these demands and facilitate their own career success.
    Keywords Education ; Training ; Clinical and translational science workforce ; Clinical and translational science awards ; Medicine ; R
    Language English
    Publishing date 2017-04-01T00:00:00Z
    Publisher Cambridge University Press
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article ; Online: KL2 scholars’ perceptions of factors contributing to sustained translational science career success

    Susan S. Smyth / Barry S. Coller / Rebecca D. Jackson / Philip A. Kern / Scott McIntosh / Emma A. Meagher / Doris M. Rubio / Kathryn Sandberg / Joel Tsevat / Jason G. Umans / Jacqueline Attia / Heather L. Baker / Joan D. Nagel / Colleen A. McMullen / Erica Rosemond

    Journal of Clinical and Translational Science, Vol

    2022  Volume 6

    Abstract: Abstract Introduction: Identifying the most effective ways to support career development of early stage investigators in clinical and translational science should yield benefits for the biomedical research community. Institutions with Clinical and ... ...

    Abstract Abstract Introduction: Identifying the most effective ways to support career development of early stage investigators in clinical and translational science should yield benefits for the biomedical research community. Institutions with Clinical and Translational Science Awards (CTSA) offer KL2 programs to facilitate career development; however, the sustained impact has not been widely assessed. Methods: A survey comprised of quantitative and qualitative questions was sent to 2144 individuals that had previously received support through CTSA KL2 mechanisms. The 547 responses were analyzed with identifying information redacted. Results: Respondents held MD (47%), PhD (36%), and MD/PhD (13%) degrees. After KL2 support was completed, physicians’ time was divided 50% to research and 30% to patient care, whereas PhD respondents devoted 70% time to research. Funded research effort averaged 60% for the cohort. Respondents were satisfied with their career progression. More than 95% thought their current job was meaningful. Two-thirds felt confident or very confident in their ability to sustain a career in clinical and translational research. Factors cited as contributing to career success included protected time, mentoring, and collaborations. Conclusion: This first large systematic survey of KL2 alumni provides valuable insight into the group’s perceptions of the program and outcome information. Former scholars are largely satisfied with their career choice and direction, national recognition of their expertise, and impact of their work. Importantly, they identified training activities that contributed to success. Our results and future analysis of the survey data should inform the framework for developing platforms to launch sustaining careers of translational scientists.
    Keywords Career development ; translational science ; career success ; career satisfaction ; work impact ; Medicine ; R
    Subject code 300
    Language English
    Publishing date 2022-01-01T00:00:00Z
    Publisher Cambridge University Press
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  10. Article: Verification of Meso-Zeaxanthin in Fish

    Beatty, Stephen , / A Meagher, Katie , / N Howard, Alan , / Kelly, David , / I Thurnham, David ,

    Food Processing & Technology

    2014. June.  , Issue (6)

    Abstract: Background/Objectives: The carotenoids lutein (L), zeaxanthin (Z), and meso-zeaxanthin (MZ) accumulate in the central retina (the macula), where they are collectively known as macular pigment (MP). MP has been shown to enhance visual function in both ... ...

    Abstract Background/Objectives: The carotenoids lutein (L), zeaxanthin (Z), and meso-zeaxanthin (MZ) accumulate in the central retina (the macula), where they are collectively known as macular pigment (MP). MP has been shown to enhance visual function in both diseased and non-diseased retinae, and therefore an understanding and confirmation of, the origins of these carotenoids is needed. Studies have shown that L and Z are present in many foodstuffs found in a typical Western diet (e.g. spinach, kale, peppers, yellow corn and eggs). It has been shown that MZ is generated from L in the primate retina and earlier reports suggested that MZ was present in some fish species. Recently, however, one research group reported that MZ is not present in fish and suggested that the earlier reports showing MZ in these marine species were a methodological artefact. The current study was designed to investigate the reason for the contradiction, and test for the presence of MZ in fish and some other foods. Methods: Raw fruits, vegetables and fish were extracted for carotenoid analysis by high performance liquid chromatography. Results: MZ was not detected in any of the fruits or vegetables tested in our study. However, using retention time matching, absorption spectrum comparison, and sample spiking, we verified the presence of MZ in salmon skin, sardine skin, trout skin and trout flesh. Conclusion: This study confirmed the presence MZ in nature, and in the human food chain.
    Language English
    Document type Article
    ISSN 2157-7110
    Database AGRIS - International Information System for the Agricultural Sciences and Technology

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