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  1. Article ; Online: Peroral endoscopic myotomy and its use in non-achalasia disorders.

    Rengarajan, Arvind / Aadam, A Aziz

    Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

    2024  

    Abstract: The aim of this review is to provide an overview of per-oral endoscopic myotomy (POEM) and its utilization in non-achalasia disorders of the esophagus. POEM, a relatively novel endoscopic technique, involves submucosal tunneling to access esophageal ... ...

    Abstract The aim of this review is to provide an overview of per-oral endoscopic myotomy (POEM) and its utilization in non-achalasia disorders of the esophagus. POEM, a relatively novel endoscopic technique, involves submucosal tunneling to access esophageal muscle layers, enabling selective myotomy and mitigating the consequences of motor disorders of the esophagus. POEM is an effective treatment modality for diffuse esophageal spasm providing resolution of chest pain and dysphagia in a majority of patients who have refractory symptoms despite medical therapy. The results of POEM are more equivocal compared to esophagogastric junction outflow obstruction (EGJOO). POEM in EGJOO has been shown to have a 93% clinical success rate in 6 months. POEM appears to be more effective in motor disorders that affect the lower esophageal sphincter, such as EGJOO and opioid-induced esophageal dysfunction. While the current data for POEM in other entities such as DES and HE are positive, more supportive data are required to make POEM a consistent recommendation for patients.
    Language English
    Publishing date 2024-03-08
    Publishing country United States
    Document type Journal Article
    ZDB-ID 639470-x
    ISSN 1442-2050 ; 1120-8694
    ISSN (online) 1442-2050
    ISSN 1120-8694
    DOI 10.1093/dote/doae014
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 2378: Show issues Location:
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  2. Article ; Online: Advances in screening and detection of gastric cancer.

    Xia, Jonathan Y / Aadam, A Aziz

    Journal of surgical oncology

    2022  Volume 125, Issue 7, Page(s) 1104–1109

    Abstract: With an estimated one million new cases and 769 000 deaths in 2020, gastric cancer is the fifth most frequent cancer and fourth leading cause of cancer death globally. Incidence rates are highest in Asia and Eastern Europe. This manuscript will review ... ...

    Abstract With an estimated one million new cases and 769 000 deaths in 2020, gastric cancer is the fifth most frequent cancer and fourth leading cause of cancer death globally. Incidence rates are highest in Asia and Eastern Europe. This manuscript will review the current modalities of diagnosis, staging, and screening of gastric cancer. We will also highlight development of novel diagnostics and advancements in endoscopic detection of early gastric cancer.
    MeSH term(s) Asia/epidemiology ; Early Detection of Cancer ; Humans ; Incidence ; Mass Screening ; Stomach Neoplasms/diagnosis ; Stomach Neoplasms/epidemiology
    Language English
    Publishing date 2022-05-22
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 82063-5
    ISSN 1096-9098 ; 0022-4790
    ISSN (online) 1096-9098
    ISSN 0022-4790
    DOI 10.1002/jso.26844
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 706: Show issues Location:
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  3. Article ; Online: T1b esophageal cancer: Is it time for endoscopic submucosal dissection to enter the stage?

    Liu, Kevin / Aadam, A Aziz

    Gastrointestinal endoscopy

    2022  Volume 96, Issue 3, Page(s) 454–456

    MeSH term(s) Endoscopic Mucosal Resection ; Esophageal Neoplasms/surgery ; Esophagectomy ; Humans ; Treatment Outcome
    Language English
    Publishing date 2022-07-19
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 391583-9
    ISSN 1097-6779 ; 0016-5107
    ISSN (online) 1097-6779
    ISSN 0016-5107
    DOI 10.1016/j.gie.2022.05.004
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  4. Article ; Online: Endoscopic submuscular dissection as a rescue for severe fibrosis after incomplete polypectomy.

    Rodrigues, Terrance J / Patel, Raeesa / Rengarajan, Arvind / Booth, Adam L / Abbass, Mohammad / Aadam, A Aziz

    VideoGIE : an official video journal of the American Society for Gastrointestinal Endoscopy

    2023  Volume 9, Issue 2, Page(s) 99–101

    Abstract: Video 1Endoscopic submuscular dissection as a rescue for severe fibrosis after incomplete polypectomy. ...

    Abstract Video 1Endoscopic submuscular dissection as a rescue for severe fibrosis after incomplete polypectomy.
    Language English
    Publishing date 2023-10-06
    Publishing country United States
    Document type Journal Article
    ISSN 2468-4481
    ISSN (online) 2468-4481
    DOI 10.1016/j.vgie.2023.09.023
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Endoscopic palliation of biliary obstruction.

    Aadam, A Aziz / Liu, Kevin

    Journal of surgical oncology

    2019  Volume 120, Issue 1, Page(s) 57–64

    Abstract: Advanced pancreaticobiliary malignancy tends to be uncurable at presentation and causes significant morbidity for patients. Palliation for malignant biliary obstruction should be minimally invasive, cost-effective, and aim to improve quality of life of ... ...

    Abstract Advanced pancreaticobiliary malignancy tends to be uncurable at presentation and causes significant morbidity for patients. Palliation for malignant biliary obstruction should be minimally invasive, cost-effective, and aim to improve quality of life of patients. Strategies of endoscopic palliation of malignant biliary obstruction can differ based on sites and degree of biliary obstruction with complex decisions of optimal stent type and placement that involve conscientious planning by a multidisciplinary team.
    MeSH term(s) Bile Duct Neoplasms/complications ; Bile Duct Neoplasms/diagnostic imaging ; Cholestasis/diagnostic imaging ; Cholestasis/etiology ; Cholestasis/surgery ; Constriction, Pathologic ; Drainage/methods ; Endoscopy, Digestive System/methods ; Humans ; Palliative Care ; Pancreatic Neoplasms/complications ; Prosthesis Implantation/methods ; Stents
    Language English
    Publishing date 2019-05-04
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 82063-5
    ISSN 1096-9098 ; 0022-4790
    ISSN (online) 1096-9098
    ISSN 0022-4790
    DOI 10.1002/jso.25483
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    Zs.A 706: Show issues Location:
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  6. Article: Advancements in Endoscopic Biliary Interventions by Gastroenterology.

    Almuhaidb, Aymen / Olson, Dylan / Aadam, A Aziz

    Seminars in interventional radiology

    2021  Volume 38, Issue 3, Page(s) 280–290

    Abstract: Endoscopic retrograde cholangiopancreatography (ERCP) is an endoscopic technique in which a specialized side-viewing endoscope is guided into the duodenum, allowing for instruments to access the biliary and pancreatic ducts. ERCP was initially developed ... ...

    Abstract Endoscopic retrograde cholangiopancreatography (ERCP) is an endoscopic technique in which a specialized side-viewing endoscope is guided into the duodenum, allowing for instruments to access the biliary and pancreatic ducts. ERCP was initially developed as a diagnostic tool as computed tomography was in its infancy during that time. ERCP has evolved since its inception in the 1960s to becoming not only a valuable diagnostic resource but now an effective therapeutic intervention in the treatment of various biliary disorders. The most common biliary interventions performed by ERCP include the management of biliary obstructions for benign and malignant indications. Additionally, endoscopic ultrasound (EUS) has been increasingly utilized in diagnosing and intervening on pancreaticobiliary lesion. This article will discuss the various methods currently available for various endoscopic biliary interventions and future interventional techniques. For the management of biliary strictures, EUS can be utilized with fine need aspiration, while ERCP can be used for the placement of various stents and diagnostic modalities. Another example is radiofrequency ablation, which can be used for the treatment of hilar strictures. Achieving bile duct access can be challenging in patients with complicated clinical scenarios; other techniques that can be used for bile duct access include EUS-guided rendezvous approach, transluminal approach, Choleodochoduodenostomy, and hepatogastrostomy, along with gaining access in complicated anatomy such as in patients with Rou-en-Y anatomy. Another useful endoscopic tool is nonsurgical drainage of the gallbladder, which can be a suitable option when patients are not optimal surgical candidates. There has also been an increase in outpatient utilization of ERCP, which was previously seen as a predominantly inpatient procedure in the past. Possible future evolutions of biliary interventions include robotic manipulation of a duodenoscope and direct infusion of chemotherapeutic or immunomodulatory agents into the pancreaticobiliary tree. These advancements will depend on parallel advancements in other imaging and laboratory as well as breakthrough technology or techniques by other disciplines including interventional radiology and minimally invasive surgery.
    Language English
    Publishing date 2021-08-10
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 848341-3
    ISSN 1098-8963 ; 0739-9529
    ISSN (online) 1098-8963
    ISSN 0739-9529
    DOI 10.1055/s-0041-1731266
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Advancements in Endoscopic Biliary Interventions by Gastroenterology

    Almuhaidb, Aymen / Olson, Dylan / Aadam, A. Aziz

    Seminars in Interventional Radiology

    (Percutaneous Biliary Interventions: Inside and Outside the Box)

    2021  Volume 38, Issue 03, Page(s) 280–290

    Abstract: Endoscopic retrograde cholangiopancreatography (ERCP) is an endoscopic technique in which a specialized side-viewing endoscope is guided into the duodenum, allowing for instruments to access the biliary and pancreatic ducts. ERCP was initially developed ... ...

    Series title Percutaneous Biliary Interventions: Inside and Outside the Box
    Abstract Endoscopic retrograde cholangiopancreatography (ERCP) is an endoscopic technique in which a specialized side-viewing endoscope is guided into the duodenum, allowing for instruments to access the biliary and pancreatic ducts. ERCP was initially developed as a diagnostic tool as computed tomography was in its infancy during that time. ERCP has evolved since its inception in the 1960s to becoming not only a valuable diagnostic resource but now an effective therapeutic intervention in the treatment of various biliary disorders. The most common biliary interventions performed by ERCP include the management of biliary obstructions for benign and malignant indications. Additionally, endoscopic ultrasound (EUS) has been increasingly utilized in diagnosing and intervening on pancreaticobiliary lesion. This article will discuss the various methods currently available for various endoscopic biliary interventions and future interventional techniques. For the management of biliary strictures, EUS can be utilized with fine need aspiration, while ERCP can be used for the placement of various stents and diagnostic modalities. Another example is radiofrequency ablation, which can be used for the treatment of hilar strictures. Achieving bile duct access can be challenging in patients with complicated clinical scenarios; other techniques that can be used for bile duct access include EUS-guided rendezvous approach, transluminal approach, Choleodochoduodenostomy, and hepatogastrostomy, along with gaining access in complicated anatomy such as in patients with Rou-en-Y anatomy. Another useful endoscopic tool is nonsurgical drainage of the gallbladder, which can be a suitable option when patients are not optimal surgical candidates. There has also been an increase in outpatient utilization of ERCP, which was previously seen as a predominantly inpatient procedure in the past. Possible future evolutions of biliary interventions include robotic manipulation of a duodenoscope and direct infusion of chemotherapeutic or immunomodulatory agents into the pancreaticobiliary tree. These advancements will depend on parallel advancements in other imaging and laboratory as well as breakthrough technology or techniques by other disciplines including interventional radiology and minimally invasive surgery.
    Keywords endoscopic biliary interventions ; advanced endoscopy ; gastroenterology
    Language English
    Publishing date 2021-08-01
    Publisher Thieme Medical Publishers, Inc.
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 848341-3
    ISSN 1098-8963 ; 0739-9529
    ISSN (online) 1098-8963
    ISSN 0739-9529
    DOI 10.1055/s-0041-1731266
    Database Thieme publisher's database

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  8. Article: Endoscopic retrograde cholangiopancreatography (ERCP) in critically ill patients is safe and effective when performed in the endoscopy suite.

    Farina, Domenico A / Komanduri, Srinadh / Aadam, A Aziz / Keswani, Rajesh N

    Endoscopy international open

    2020  Volume 8, Issue 9, Page(s) E1165–E1172

    Abstract: Background and study ... ...

    Abstract Background and study aims
    Language English
    Publishing date 2020-08-31
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2761052-4
    ISSN 2196-9736 ; 2364-3722
    ISSN (online) 2196-9736
    ISSN 2364-3722
    DOI 10.1055/a-1194-4049
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Endoscopic retrograde cholangiopancreatography (ERCP) in critically ill patients is safe and effective when performed in the endoscopy suite

    Farina, Domenico A. / Komanduri, Srinadh / Aadam, A. Aziz / Keswani, Rajesh N.

    Endoscopy International Open

    2020  Volume 08, Issue 09, Page(s) E1165–E1172

    Abstract: Background and study aims: Critically ill patients may require endoscopic retrograde cholangiopancreatography (ERCP) but performing ERCP in the intensive care unit (ICU) poses logistic and technical challenges. There are no data on ICU patients ... ...

    Abstract Background and study aims: Critically ill patients may require endoscopic retrograde cholangiopancreatography (ERCP) but performing ERCP in the intensive care unit (ICU) poses logistic and technical challenges. There are no data on ICU patients undergoing ERCP in the endoscopy suite. The primary aim of this study was to report outcomes, including safety, when ERCP in critically ill patients is performed in the endoscopy suite.
    Patients and methods : We queried our institutional endoscopy database to identify all ICU patients who underwent ERCP at a single academic medical center from 04/01/2010 to 11/30/2017. Only patients admitted to an ICU prior to ERCP were included.
    Results : Of 7,218 ERCPs performed during the study period, 260 ERCPs (3.6 %) were performed in 231 ICU patients (mean age 61y; 53 % male); nearly all ICU patient ERCPs (n = 258; 99 %) occurred in the endoscopy suite. ERCP indications included cholangitis (50 %), post-liver transplant cholestasis (15 %), and bile leak (10 %). All ERCPs were performed with anesthesiology, most with general anesthesia (60 %) and in the prone position (60 %). Most patients (73 %) had sepsis. Prior to ERCP, 17 % of patients required vasopressors; vasopressors were begun during ERCP in 4 %. The cannulation success rate was 95 % (94 % in native papillae). Adverse events occurred in 9 % (n = 23) of cases with post-ERCP pancreatitis most common. No patients died during or within 24 hours of ERCP. Mortality at 30 days was 16 %, all attributed to underlying disease.
    Conclusions : When advanced ventilatory and hemodynamic support is available, critically ill patients can safely and effectively undergo ERCP in the endoscopy suite.
    Language English
    Publishing date 2020-08-31
    Publisher © Georg Thieme Verlag KG
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 2761052-4
    ISSN 2196-9736 ; 2364-3722 ; 2196-9736
    ISSN (online) 2196-9736
    ISSN 2364-3722 ; 2196-9736
    DOI 10.1055/a-1194-4049
    Database Thieme publisher's database

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  10. Article ; Online: Enteral stents in malignant bowel obstruction.

    Aadam, A Aziz / Martin, John A

    Gastrointestinal endoscopy clinics of North America

    2013  Volume 23, Issue 1, Page(s) 153–164

    Abstract: Colorectal stent placement offers a minimally invasive approach for relief of malignant bowel obstruction. Stent placement is safe and effective in carefully selected patients as a bridge to surgery or for definitive palliation of obstruction. Concerns ... ...

    Abstract Colorectal stent placement offers a minimally invasive approach for relief of malignant bowel obstruction. Stent placement is safe and effective in carefully selected patients as a bridge to surgery or for definitive palliation of obstruction. Concerns remain regarding the long-term efficacy of stent placement and related complications. Future studies are needed to identify patients who are the best candidates for stent placement.
    MeSH term(s) Endoscopy, Gastrointestinal/methods ; Gastrointestinal Neoplasms/surgery ; Humans ; Intestinal Obstruction/surgery ; Palliative Care ; Postoperative Complications ; Stents ; Treatment Outcome
    Language English
    Publishing date 2013-01
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 1313994-0
    ISSN 1558-1950 ; 1052-5157
    ISSN (online) 1558-1950
    ISSN 1052-5157
    DOI 10.1016/j.giec.2012.10.006
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