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  1. Book: Searching for perfection: further progress in management of chemotherapy-induced nausea and vomiting

    Aapro, Matti S.

    (Supportive care in cancer ; volume 26, supplement 1 (March 2018))

    2018  

    Title variant Special section title: Searching for perfection: further progress in management of chemotherapy-induced nausea and vomiting
    Author's details guest editor: Matti Aapro, MD
    Series title Supportive care in cancer ; volume 26, supplement 1 (March 2018)
    Collection
    Language English
    Size S37 Seiten, Illustrationen
    Publisher Springer
    Publishing place Berlin
    Publishing country Germany
    Document type Book
    HBZ-ID HT019695961
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

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    Zs A 3697 -26,Suppl.1- not available for loan Zeitschriften-Lesesaal

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  2. Article ; Online: Characteristics of nausea and its impact on health-related quality of life in cisplatin-treated patients receiving dexamethasone-sparing prophylaxis: an analysis of the LUNG-NEPA study.

    Celio, Luigi / Aapro, Matti

    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer

    2024  Volume 32, Issue 3, Page(s) 204

    Abstract: Purpose: We investigated the intensity and duration of nausea as well as its impact on health-related quality of life among cisplatin-treated patients who participated in a study of dexamethasone (DEX)-sparing regimens based on NEPA (netupitant/ ... ...

    Abstract Purpose: We investigated the intensity and duration of nausea as well as its impact on health-related quality of life among cisplatin-treated patients who participated in a study of dexamethasone (DEX)-sparing regimens based on NEPA (netupitant/palonosetron).
    Methods: This retrospective analysis included chemo-naive patients from a trial evaluating non-inferiority of DEX on day 1 (DEX1 arm) combined with NEPA, compared with the same regimen with DEX administered on days 1-4 (DEX4; reference arm) following cisplatin (≥ 70 mg/m
    Results: In the DEX1 arm, more patients (20/76) experienced acute nausea, influencing the outcome of delayed nausea (38/76). During days 1 to 5, 51.3% (39/76) and 39.5% (30/76) of patients experienced nausea in the DEX1 and DEX4 arms, respectively (P = 0.192). Of these, 43.6% and 60% reported moderate-to-severe nausea, respectively, in the DEX1 and DEX4 arms (P = 0.200), while 74.4% and 56.7% of patients experienced extended nausea duration (P = 0.122). Similar between-arm rates of nauseated patients reported an impact on daily life (79.5% vs. 70%; P = 0.408). In analyses stratified for antiemetic regimen, moderate-to-severe nausea or extended nausea duration was associated with an impact on daily life (P ≤ 0.001).
    Conclusion: Despite the higher incidence, there was no suggestion of any strong adverse effect of NEPA plus single-dose DEX on the characteristics of nausea as well as its impact on daily life in patients with cisplatin-induced nausea. Further prospective controlled study is warranted.
    Trial registration: ClinicalTrials.gov identifier: NCT04201769. Registration date: 17/12/2019.
    MeSH term(s) Humans ; Quality of Life ; Cisplatin/adverse effects ; Retrospective Studies ; Nausea/chemically induced ; Nausea/epidemiology ; Nausea/prevention & control ; Dexamethasone/therapeutic use ; Lung
    Chemical Substances Cisplatin (Q20Q21Q62J) ; Dexamethasone (7S5I7G3JQL)
    Language English
    Publishing date 2024-03-04
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1134446-5
    ISSN 1433-7339 ; 0941-4355
    ISSN (online) 1433-7339
    ISSN 0941-4355
    DOI 10.1007/s00520-024-08406-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3697: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  3. Book: New and emerging therapeutic options for the management of chemotherapy-induced nausea and vomiting

    Schwartzberg, Lee S. / Rugo, Hope S. / Aapro, Matti S.

    (Clinical advances in hematology & oncology : Clinical roundtable monograph ; volume 13, issue 3, supplement 3 (March 2015))

    2015  

    Author's details discussants Lee S. Schwartzberg, MD; Hope S. Rugo, MD; Matti S. Aapro, MD
    Series title Clinical advances in hematology & oncology : Clinical roundtable monograph ; volume 13, issue 3, supplement 3 (March 2015)
    Clinical advances in hematology & oncology
    Clinical advances in hematology & oncology
    Collection Clinical advances in hematology & oncology
    Clinical advances in hematology & oncology
    Language English
    Size 14 Seiten, Diagramme
    Publisher Millennium Medical Publishing
    Publishing place New York, NY
    Publishing country United States
    Document type Book
    HBZ-ID HT019339121
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    Zs A 6505 -13,Suppl.3- verfügbar in Königswinter Königswinter

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  4. Book: Advances in the management of chemotherapy-induced nausea and vomiting: new data from recent and ongoing trials

    Wong, Eric T. / Aapro, Matti S. / Schwartzberg, Lee S.

    (Clinical advances in hematology & oncology : Clinical roundtable monograph ; volume 13, issue 10, supplement 10 (October 2015))

    2015  

    Author's details discussants Eric Roeland, MD; Matti S. Aapro, MD; Lee S. Schwartzberg, MD
    Series title Clinical advances in hematology & oncology : Clinical roundtable monograph ; volume 13, issue 10, supplement 10 (October 2015)
    Clinical advances in hematology & oncology
    Clinical advances in hematology & oncology
    Collection Clinical advances in hematology & oncology
    Clinical advances in hematology & oncology
    Language English
    Size 14 Seiten, Diagramme
    Publisher Millennium Medical Publishing
    Publishing place New York, NY
    Publishing country United States
    Document type Book
    HBZ-ID HT019339012
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    Zs A 6505 -13,Suppl.10- verfügbar in Königswinter Königswinter

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  5. Book ; Conference proceedings: Moving forward with new data and approaches: a fresh look at anthracyclines in breast cancer

    Amadori, Dino / Aapro, Matti S.

    summary of a workshop held in September 2010 [International Workshop Moving Forward With New Data and Approaches: A Fresh Look at Anthracyclines in Breast Cancer and NHL]

    (EJC Supplements ; 9,2)

    2011  

    Event/congress International Workshop Moving Forward With New Data and Approaches: A Fresh Look at Anthracyclines in Breast Cancer and NHL (2010, Meldola)
    Author's details guest ed.: Dino Amadori and Matti Aapro
    Series title EJC Supplements ; 9,2
    European journal of cancer
    Collection European journal of cancer
    Language English
    Size 42 S. : graph. Darst.
    Publisher Elsevier
    Publishing place Amsterdam u.a.
    Publishing country Netherlands
    Document type Book ; Conference proceedings
    HBZ-ID HT017108280
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

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    Zs A 456 -Suppl.9,2- not available for loan Zeitschriften-Lesesaal

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  6. Book ; Conference proceedings: Optimizng breast cancer patient care today and tomorrow

    Aapro, Matti S.

    implications for clinicians ; [2007 Educational Breast Care Meeting "Optimizing Breast Cancer Patient Care Today and Tomorrow: Implications for Clinicians", held in Barcelona, Spain]

    (Breast cancer research and treatment ; 112, Suppl. 1)

    2008  

    Event/congress Educational Breast Care Meeting Optimizing Breast Cancer Patient Care Today and Tomorrow: Implications for Clinicians (2007, Barcelona)
    Author's details guest ed. Matti S. Aapro
    Series title Breast cancer research and treatment ; 112, Suppl. 1
    Collection
    Language English
    Size 66 S. : graph. Darst.
    Publisher Springer
    Publishing place Dordrecht u.a.
    Publishing country Netherlands
    Document type Book ; Conference proceedings
    HBZ-ID HT015837459
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

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    Zs A 1655 -112,Suppl.1- not available for loan Zeitschriften-Lesesaal

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  7. Book ; Conference proceedings: Controversies in endocrine treatment

    Aapro, Matti S.

    effective utilization of steroidal and nonsteroidal aromatase inhibitors: now and in the future ; based on a satellite symposium held during the 10th International Conference on Primary Therapy of Early Breast Cancer, St. Gallen, Switzerland, March 2007 ; [Symposium on "Controversies in Endocrine Treatment"]

    (Anti-cancer drugs ; 19, Suppl. 2)

    2008  

    Event/congress International Conference Primary Therapy of Early Breast Cancer (10, 2007, SanktGallen) ; Symposium on Controversies in Endocrine Treatment (2007, SanktGallen)
    Author's details guest ed.: Matti Aapro
    Series title Anti-cancer drugs ; 19, Suppl. 2
    Collection
    Language English
    Size S13 S. : graph. Darst.
    Publisher Lippincott Williams & Wilkins
    Publishing place London
    Publishing country Great Britain
    Document type Book ; Conference proceedings
    HBZ-ID HT015540031
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

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    Zs A 3125 -19,Suppl.2- not available for loan Zeitschriften-Lesesaal

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  8. Article ; Online: Comment on "Dexamethasone-sparing on days 2-4 with combined palonosteron, neurokinin-1 receptor antagonist, and olanzapine in cisplatin: a randomized phase III trial (SPARED Trial)".

    Celio, Luigi / Antonuzzo, Andrea / Aapro, Matti S

    British journal of cancer

    2024  Volume 130, Issue 6, Page(s) 895–896

    MeSH term(s) Humans ; Cisplatin ; Clinical Trials, Phase III as Topic ; Dexamethasone ; Neurokinin-1 Receptor Antagonists/therapeutic use ; Olanzapine ; Randomized Controlled Trials as Topic
    Chemical Substances Cisplatin (Q20Q21Q62J) ; Dexamethasone (7S5I7G3JQL) ; Neurokinin-1 Receptor Antagonists ; Olanzapine (N7U69T4SZR)
    Language English
    Publishing date 2024-02-26
    Publishing country England
    Document type Letter
    ZDB-ID 80075-2
    ISSN 1532-1827 ; 0007-0920
    ISSN (online) 1532-1827
    ISSN 0007-0920
    DOI 10.1038/s41416-024-02611-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Uh III Zs.142: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  9. Book: Prevention of nausea and vomiting in cancer patients

    Aapro, Matti S. / Jordan, Karin / Feyer, Petra

    2013  

    Author's details Matti Aapro ; Karin Jordan ; Petra Feyer
    Language English
    Size IX, 59 S. : Ill.
    Publisher Springer Healthcare
    Publishing place London
    Publishing country Great Britain
    Document type Book
    HBZ-ID HT018105170
    ISBN 978-1-908517-87-6 ; 1-908517-87-5
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2013 A 4163 available for loan (reading room) Lesesaal EG

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  10. Article ; Online: CINV: still troubling patients after all these years.

    Aapro, Matti

    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer

    2018  Volume 26, Issue Suppl 1, Page(s) 5–9

    Abstract: Chemotherapy-induced nausea and vomiting (CINV) is one of the most feared side effects experienced by patients with cancer. The precise physiologic mechanisms responsible for acute and delayed CINV continue to be elucidated and have provided an ... ...

    Abstract Chemotherapy-induced nausea and vomiting (CINV) is one of the most feared side effects experienced by patients with cancer. The precise physiologic mechanisms responsible for acute and delayed CINV continue to be elucidated and have provided an opportunity to develop antiemetic therapies targeting these pathways. The emergence of receptor antagonists targeting serotonin and neurokinin-1 have revolutionized the prevention of CINV, significantly reducing the impact of this side effect and improving patient quality of life. However, several areas of unmet need remain, including adequate prevention of nausea, rather than just vomiting, in patients receiving chemotherapy for cancer. Prevention of delayed CINV and anticipatory CINV, as well as management of breakthrough CINV, also continues to challenge patients and clinicians. Ongoing research continues to address these areas to improve antiemetic therapies and guidelines.
    MeSH term(s) Antiemetics/therapeutic use ; Humans ; Nausea/chemically induced ; Nausea/physiopathology ; Neoplasms/complications ; Neoplasms/drug therapy ; Quality of Life/psychology ; Vomiting/chemically induced ; Vomiting/physiopathology
    Chemical Substances Antiemetics
    Language English
    Publishing date 2018-03-19
    Publishing country Germany
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1134446-5
    ISSN 1433-7339 ; 0941-4355
    ISSN (online) 1433-7339
    ISSN 0941-4355
    DOI 10.1007/s00520-018-4131-3
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3697: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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