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  1. Article ; Online: Management of peri-surgical anemia in elective surgery. Conclusions and recommendations according to Delphi-UCLA methodology.

    Moral, V / Abad Motos, A / Jericó, C / Antelo Caamaño, M L / Ripollés Melchor, J / Bisbe Vives, E / García Erce, J A

    Revista espanola de anestesiologia y reanimacion

    2024  

    Abstract: Introduction: Preoperative anemia affects approximately one third of surgical patients. It increases the risk of blood transfusion and influences short- and medium-term functional outcomes, increases comorbidities, complications and costs. The "Patient ... ...

    Abstract Introduction: Preoperative anemia affects approximately one third of surgical patients. It increases the risk of blood transfusion and influences short- and medium-term functional outcomes, increases comorbidities, complications and costs. The "Patient Blood Management" (PBM) programs, for integrated and multidisciplinary management of patients, are considered as paradigms of quality care and have as one of the fundamental objectives to correct perioperative anemia. PBM has been incorporated into the schemes for intensified recovery of surgical patients: the recent Enhanced Recovery After Surgery 2021 pathway (in Spanish RICA 2021) includes almost 30 indirect recommendations for PBM.
    Objective: To make a consensus document with RAND/UCLA Delphi methodology to increase the penetration and priority of the RICA 2021 recommendations on PBM in daily clinical practice.
    Material and methods: A coordinating group composed of 6 specialists from Hematology-Hemotherapy, Anesthesiology and Internal Medicine with expertise in anemia and PBM was formed. A survey was elaborated using Delphi RAND/UCLA methodology to reach a consensus on the key areas and priority professional actions to be developed at the present time to improve the management of perioperative anemia. The survey questions were extracted from the PBM recommendations contained in the RICA 2021 pathway. The development of the electronic survey (Google Platform) and the management of the responses was the responsibility of an expert in quality of care and clinical safety. Participants were selected by invitation from speakers at AWGE-GIEMSA scientific meetings and national representatives of PBM-related working groups (Seville Document, SEDAR HTF section and RICA 2021 pathway participants). In the first round of the survey, the anonymized online questionnaire had 28 questions: 20 of them were about PBM concepts included in ERAS guidelines (2 about general PBM organization, 10 on diagnosis and treatment of preoperative anemia, 3 on management of postoperative anemia, 5 on transfusion criteria) and 8 on pending aspects of research. Responses were organized according to a 10-point Likter scale (0: strongly disagree to 10: strongly agree). Any additional contributions that the participants considered appropriate were allowed. They were considered consensual because all the questions obtained an average score of more than 9 points, except one (question 14). The second round of the survey consisted of 37 questions, resulting from the reformulation of the questions of the first round and the incorporation of the participants' comments. It consisted of 2 questions about general organization of PBM programme, 15 questions on the diagnosis and treatment of preoperative anemia; 3 on the management of postoperative anemia, 6 on transfusional criteria and finally 11 questions on aspects pending od future investigations. Statistical treatment: tabulation of mean, median and interquartiles 25-75 of the value of each survey question (Tables 1, 2 and 3).
    Results: Except for one, all the recommendations were accepted. Except for three, all above 8, and most with an average score of 9 or higher. They are grouped into: 1.- "It is important and necessary to detect and etiologically diagnose any preoperative anemia state in ALL patients who are candidates for surgical procedures with potential bleeding risk, including pregnant patients". 2.- "The preoperative treatment of anemia should be initiated sufficiently in advance and with all the necessary hematinic contributions to correct this condition". 3.- "There is NO justification for transfusing any unit of packed red blood cells preoperatively in stable patients with moderate anemia Hb 8-10 g/dL who are candidates for potentially bleeding surgery that cannot be delayed." 4.- "It is recommended to universalize restrictive criteria for red blood cell transfusion in surgical and obstetric patients." 5.- "Postoperative anemia should be treated to improve postoperative results and accelerate postoperative recovery in the short and medium term".
    Conclusions: There was a large consensus, with maximum acceptance,strong level of evidence and high recommendation in most of the questions asked. Our work helps to identify initiatives and performances who can be suitables for the implementation of PBM programs at each hospital and for all patients.
    Language English
    Publishing date 2024-04-24
    Publishing country Spain
    Document type Journal Article
    ISSN 2341-1929
    ISSN (online) 2341-1929
    DOI 10.1016/j.redare.2024.04.015
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Effect of the first wave of COVID-19 on the implementation of Enhanced Recovery After Surgery (ERAS) protocols based on perceptions of healthcare professionals.

    Lorente, J V / Ripollés-Melchor, J / Aldecoa, C / Abad-Motos, A

    Revista espanola de anestesiologia y reanimacion

    2022  Volume 69, Issue 6, Page(s) 374–376

    MeSH term(s) COVID-19 ; Delivery of Health Care ; Enhanced Recovery After Surgery ; Humans ; Length of Stay ; Perioperative Care/methods
    Language English
    Publishing date 2022-06-24
    Publishing country Spain
    Document type Letter
    ISSN 2341-1929
    ISSN (online) 2341-1929
    DOI 10.1016/j.redare.2021.09.003
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  3. Article ; Online: Efecto de la primera ola de la pandemia COVID-19 en la aplicación de los protocolos de recuperación intensificada perioperatoria según la percepción de los profesionales sanitarios.

    Lorente, J V / Ripollés-Melchor, J / Aldecoa, C / Abad-Motos, A

    Revista espanola de anestesiologia y reanimacion

    2021  Volume 69, Issue 6, Page(s) 374–376

    Title translation Effect of the first wave of COVID-19 on the implementation of Enhanced Recovery After Surgery (ERAS) protocols based on perceptions of healthcare professionals.
    Language Spanish
    Publishing date 2021-10-09
    Publishing country Spain
    Document type Journal Article
    ZDB-ID 604162-0
    ISSN 2340-3284 ; 0034-9356 ; 1131-4044
    ISSN (online) 2340-3284
    ISSN 0034-9356 ; 1131-4044
    DOI 10.1016/j.redar.2021.09.009
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Enhanced Recovery After Surgery (ERAS) in Surgical Oncology.

    Ripollés-Melchor, Javier / Abad-Motos, Ane / Zorrilla-Vaca, Andrés

    Current oncology reports

    2022  Volume 24, Issue 9, Page(s) 1177–1187

    Abstract: Purpose of the review: The objective of this review is to address the rationale behind the application of the Enhanced Recovery After Surgery (ERAS) protocols that could improve oncologic outcomes in adult patients undergoing major surgery.: Recent ... ...

    Abstract Purpose of the review: The objective of this review is to address the rationale behind the application of the Enhanced Recovery After Surgery (ERAS) protocols that could improve oncologic outcomes in adult patients undergoing major surgery.
    Recent findings: The implementation of ERAS protocols has been associated with fewer postoperative complications as well as decreased return to intended oncologic treatment (RIOT). However, few studies have analyzed the influence of the application of ERAS protocols and long-term oncologic outcomes, although some of its individual elements have been associated with improvements in oncologic outcomes, including overall survival and disease-free survival. Targeted long-term follow-up studies in specific oncologic procedures are required to determine whether ERAS application results in improved oncologic outcomes.
    MeSH term(s) Adult ; Disease-Free Survival ; Enhanced Recovery After Surgery ; Humans ; Length of Stay ; Postoperative Complications ; Surgical Oncology
    Language English
    Publishing date 2022-04-11
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2057359-5
    ISSN 1534-6269 ; 1523-3790
    ISSN (online) 1534-6269
    ISSN 1523-3790
    DOI 10.1007/s11912-022-01282-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Optimizing atrial sensing parameters in leadless pacemakers: Atrioventricular synchrony achievement in the real world.

    Briongos-Figuero, Sem / Estévez-Paniagua, Álvaro / Sánchez Hernández, Ana / Jiménez, Silvia / Gómez-Mariscal, Eloy / Abad Motos, Ane / Muñoz-Aguilera, Roberto

    Heart rhythm

    2022  Volume 19, Issue 12, Page(s) 2011–2018

    Abstract: Background: Performance of the leadless pacemaker capable of atrioventricular (AV) synchronous pacing in de novo patients warrants further investigation.: Objective: The aims of this study were to assess what programming changes are needed to achieve ...

    Abstract Background: Performance of the leadless pacemaker capable of atrioventricular (AV) synchronous pacing in de novo patients warrants further investigation.
    Objective: The aims of this study were to assess what programming changes are needed to achieve proper atrial tracking and to study the percentage of AV synchrony (AVS) the device can provide under real-world conditions.
    Methods: Consecutive patients undergoing Micra AV implantation between June 2020 and November 2021 were studied. Reprogramming of atrial sensing parameters during follow-up was performed by following device counters. AVS was studied with an ambulatory 24-hour Holter monitor and automatically analyzed by an electrocardiogram delineation system. The primary end point was AVS ≥85% of total cardiac cycles during 24-hour Holter electrocardiogram monitoring.
    Results: Thirty-one patients who remained in VDD mode were studied, and all of them required manual reprogramming. The automatic A3 window end was deactivated, and a fixed and short value was set in all patients throughout follow-up. AVS significantly increased from 68.7% ± 14.7% at 24-hour follow-up to 83.9% ± 7.4% at 1-month visit (P = .001). At 1-month visit, shorter A3 window end time (P = .019), higher A4 threshold (P = .011), and deactivation of the automatic A3 window (P = .054) were independently related to higher AVS. A total of 2,291,953 Holter-recorded cardiac cycles were analyzed. Median AVS during 24-hour daily activities was 87.6% (interquartile range 84.5%-90.6%). Twenty of 26 patients (79.6%) reached AVS ≥85% of cardiac cycles.
    Conclusion: High rates of AVS can be achieved in real-world patients undergoing leadless pacing. Manual reprogramming of the atrial sensing parameters is essential to optimize mechanically sensed atrial tracking.
    MeSH term(s) Humans ; Heart Block ; Pacemaker, Artificial ; Heart Atria ; Electrocardiography, Ambulatory ; Electrocardiography ; Cardiac Pacing, Artificial
    Language English
    Publishing date 2022-08-08
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2229357-7
    ISSN 1556-3871 ; 1547-5271
    ISSN (online) 1556-3871
    ISSN 1547-5271
    DOI 10.1016/j.hrthm.2022.08.007
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  6. Article ; Online: Association between preoperative baseline pulse pressure and estimated pulse wave velocity and acute renal failure and mortality following colorectal surgery. A single-centre observational study.

    Ripollés-Melchor, J / Fernández Dorado, F / Rubio Aguilera, A I / Criado Camargo, A / Chico García, M / Abad-Motos, A / Abad-Gurumeta, A

    Revista espanola de anestesiologia y reanimacion

    2021  Volume 68, Issue 10, Page(s) 564–575

    Abstract: Background: Elevated pulse wave velocity is a haemodynamic parameter considered to be a risk factor for the development of cardiovascular alterations, while pulse pressure is a predictor of cardiovascular complications and development of acute renal ... ...

    Abstract Background: Elevated pulse wave velocity is a haemodynamic parameter considered to be a risk factor for the development of cardiovascular alterations, while pulse pressure is a predictor of cardiovascular complications and development of acute renal failure after both cardiac and non-cardiac surgery. Our objective was to determine whether baseline pulse pressure and estimated pulse wave velocity are associated with renal failure and 30-day mortality following colorectal surgery.
    Methods: Retrospective observational study. A total of 816 adult patients undergoing elective colorectal surgery were evaluated by performing multivariable logistic regression analysis to determine whether baseline pulse pressure and estimated pulse wave velocity were independently associated with complications, specifically renal failure and 30-day postoperative mortality, and whether pulse pressure and estimated pulse wave velocity thresholds correlated with outcomes.
    Results: Baseline pulse pressure was 56.00 mmHg (45.00;68.00) and estimated pulse wave velocity was 13.16 m/s (10.76;14.85). Baseline pulse pressure was not associated with acute renal failure or mortality in the univariate model. Baseline estimated pulse wave velocity was not associated with complications, acute renal failure, or mortality. An estimated pulse wave velocity of 13.78 m/s significantly predicted acute renal failure (AUC 0.654 [0.588-0.720]) and mortality (AUC 0.698 [0.600-0.796]).
    Conclusions: Neither pulse pressure nor preoperative baseline estimated pulse wave velocity were associated with acute renal failure or postoperative mortality. The preoperative estimated pulse wave velocity threshold of 13.78 m/s predicted an increased risk of acute renal failure and postoperative mortality.
    MeSH term(s) Acute Kidney Injury/etiology ; Adult ; Blood Pressure ; Colorectal Surgery ; Humans ; Pulse Wave Analysis ; Risk Factors
    Language English
    Publishing date 2021-11-27
    Publishing country Spain
    Document type Journal Article ; Observational Study
    ISSN 2341-1929
    ISSN (online) 2341-1929
    DOI 10.1016/j.redare.2021.02.004
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  7. Article ; Online: Association between preoperative baseline pulse pressure and estimated pulse wave velocity and acute renal failure and mortality following colorectal surgery. A single-centre observational study.

    Ripollés-Melchor, J / Fernández Dorado, F / Rubio Aguilera, A I / Criado Camargo, A / Chico García, M / Abad-Motos, A / Abad-Gurumeta, A

    Revista espanola de anestesiologia y reanimacion

    2021  

    Abstract: Background: Elevated pulse wave velocity is a haemodynamic parameter considered to be a risk factor for the development of cardiovascular alterations, while pulse pressure is a predictor of cardiovascular complications and development of acute renal ... ...

    Title translation Asociación entre la presión de pulso y la velocidad onda pulso estimada basal preoperatoria con las complicaciones postoperatorias, insuficiencia renal aguda y mortalidad tras cirugía colorrectal. Estudio unicéntrico observacional.
    Abstract Background: Elevated pulse wave velocity is a haemodynamic parameter considered to be a risk factor for the development of cardiovascular alterations, while pulse pressure is a predictor of cardiovascular complications and development of acute renal failure after both cardiac and non-cardiac surgery. Our objective was to determine whether baseline pulse pressure and estimated pulse wave velocity are associated with renal failure and 30-day mortality following colorectal surgery.
    Methods: Retrospective observational study. A total of 816 adult patients undergoing elective colorectal surgery were evaluated by performing multivariable logistic regression analysis to determine whether baseline pulse pressure and estimated pulse wave velocity were independently associated with complications, specifically renal failure and 30-day postoperative mortality, and whether pulse pressure and estimated pulse wave velocity thresholds correlated with outcomes.
    Results: Baseline pulse pressure was 56.00mmHg (45.00;68.00) and estimated pulse wave velocity was 13.16m/s (10.76;14.85). Baseline pulse pressure was not associated with acute renal failure or mortality in the univariate model. Baseline estimated pulse wave velocity was not associated with complications, acute renal failure, or mortality. An estimated pulse wave velocity of 13.78m/s significantly predicted acute renal failure (AUC 0.654 [0.588-0.720]) and mortality (AUC 0.698 [0.600-0.796]).
    Conclusions: Neither pulse pressure nor preoperative baseline estimated pulse wave velocity were associated with acute renal failure or postoperative mortality. The preoperative estimated pulse wave velocity threshold of 13.78m/s predicted an increased risk of acute renal failure and postoperative mortality.
    Language Spanish
    Publishing date 2021-07-18
    Publishing country Spain
    Document type Journal Article
    ISSN 2341-1929
    ISSN (online) 2341-1929
    DOI 10.1016/j.redar.2021.02.006
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  8. Article ; Online: Patient Blood Management for primary hip and knee replacement. A survey among POWER.2 study researchers.

    Abad-Motos, A / Ripollés-Melchor, J / Jericó, C / Basora, M / Aldecoa, C / Cabellos-Olivares, M / Navarro-Pérez, R / Bisbe, E / García-Erce, J A

    Revista espanola de anestesiologia y reanimacion

    2020  Volume 67, Issue 5, Page(s) 237–244

    Abstract: Background: Implementation of Patient Blood Management programs remain variable in Europe, and even in centres with well-established PBM programs variability exists in transfusion practices.: Objectives and methods: We conducted a survey in order to ... ...

    Title translation Patient Blood Management en artroplastia primaria de cadera y rodilla. Encuesta entre los investigadores del estudio POWER.2.
    Abstract Background: Implementation of Patient Blood Management programs remain variable in Europe, and even in centres with well-established PBM programs variability exists in transfusion practices.
    Objectives and methods: We conducted a survey in order to assess current practice in perioperative Patient Blood Management in patients undergoing total hip and knee replacement among researchers involved in POWER.2 Study in Spain (an observational prospective study evaluating enhanced recovery pathways in orthopaedic surgery).
    Results: A total of 322 responses were obtained (37.8%). Half of responders check Haemoglobin levels in patients at least 4 weeks before surgery; 35% treat all anaemic patients, although 99.7% consider detection and treatment of preoperative anaemia could influence the postoperative outcomes. Lack of infrastructure (76%) and lack of time (51%) are the main stated reasons not to treat anaemic patients. Iron status is routinely checked by 19% before surgery, and 36% evaluate it solely in the anaemic patient. Hb<9.9 g/dl is the threshold to delay surgery for 61% of clinicians, and 22% would consider transfusing preoperatively clinically stable patients without active bleeding. The threshold to transfuse patients without cardiovascular disease is 8 g/dl for 43%, and 7 g/dl for 34% of the responders; 75% of clinicians consider they use "restrictive thresholds", and 90% follow the single unit transfusion policy.
    Conclusions: The results of our survey show variability in clinical practice in Patient Blood Management in major orthopaedic surgery, despite being the surgery with the greatest tradition in these programs.
    MeSH term(s) Anemia/diagnosis ; Anemia/therapy ; Anesthesiologists/statistics & numerical data ; Arthroplasty, Replacement, Hip/standards ; Arthroplasty, Replacement, Knee/standards ; Blood Transfusion/statistics & numerical data ; Female ; Health Care Surveys/statistics & numerical data ; Hemoglobin A/analysis ; Humans ; Iron/administration & dosage ; Iron/blood ; Male ; Orthopedic Procedures/statistics & numerical data ; Postoperative Hemorrhage/prevention & control ; Preoperative Care/standards ; Preoperative Care/statistics & numerical data ; Program Evaluation ; Prospective Studies ; Spain
    Chemical Substances Hemoglobin A (9034-51-9) ; Iron (E1UOL152H7)
    Language Spanish
    Publishing date 2020-03-09
    Document type Journal Article ; Observational Study
    ISSN 2341-1929
    ISSN (online) 2341-1929
    DOI 10.1016/j.redar.2020.01.013
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  9. Article ; Online: Leadless atrioventricular synchronous pacing: a validation pilot study with Holter monitoring.

    Briongos Figuero, Sem / Estévez Paniagua, Álvaro / Sánchez Hernández, Ana / Abad-Motos, Ane / Ruiz, Alicia / Muñoz-Aguilera, Roberto

    Revista espanola de cardiologia (English ed.)

    2021  Volume 74, Issue 11, Page(s) 992–993

    MeSH term(s) Cardiac Pacing, Artificial ; Electrocardiography, Ambulatory ; Equipment Design ; Humans ; Pacemaker, Artificial ; Pilot Projects
    Language Spanish
    Publishing date 2021-06-29
    Publishing country Spain
    Document type Case Reports
    ZDB-ID 2592481-3
    ISSN 1885-5857 ; 1885-5857
    ISSN (online) 1885-5857
    ISSN 1885-5857
    DOI 10.1016/j.rec.2021.06.004
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  10. Article ; Online: PBM: Now more than ever necessary.

    García-Erce, J A / Jericó, C / Abad-Motos, A / Rodríguez García, J / Antelo Caamaño, M L / Domingo Morera, J M / Sola Lapeña, C / Arroyo, J L / Fernández Fuertes, F / Zalba Marcos, S / Cerdán Rodríguez, G / Laso Morales, M J / Bueno Cabrera, J L / Chica, E / Recasens, V / Zabalegui, A / Balen, E / Urrechaga, E / Abad-Gurumeta, A /
    Quintana Díaz, M

    Revista espanola de anestesiologia y reanimacion

    2022  Volume 69, Issue 6, Page(s) 351–354

    Language English
    Publishing date 2022-06-24
    Publishing country Spain
    Document type Journal Article
    ISSN 2341-1929
    ISSN (online) 2341-1929
    DOI 10.1016/j.redare.2021.03.016
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