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  1. Article ; Online: Angiographic evolution of myocardial perfusion impairment in a single case of Tako-Tsubo like syndrome.

    Valbusa, A / Abbadessa, F / Giachero, C / Chiarella, F

    International journal of cardiology

    2014  Volume 172, Issue 1, Page(s) e82–3

    MeSH term(s) Coronary Angiography/methods ; Coronary Circulation/physiology ; Female ; Humans ; Male ; Takotsubo Cardiomyopathy/diagnostic imaging
    Language English
    Publishing date 2014
    Publishing country Netherlands
    Document type Letter ; Comment
    ZDB-ID 779519-1
    ISSN 1874-1754 ; 0167-5273
    ISSN (online) 1874-1754
    ISSN 0167-5273
    DOI 10.1016/j.ijcard.2013.12.044
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  2. Article: Clinical Characteristics and Long-Term Mortality Rate in Female Patients with Takotsubo Syndrome Compared with Female Patients with ST-Elevation Acute Myocardial Infarction: A Retrospective Study from a Single Center.

    Massobrio, Laura / Valbusa, Alberto / Sartini, Marina / Meliota, Giovanni / Cavalla, Francesca / Miceli, Roberta / Vischi, Giulia / Cristina, Maria Luisa / Spagnolo, Anna Maria / Delfino, Roberto / Abbadessa, Francesco / Porto, Italo / Brunelli, Claudio / Rosa, Gian Marco

    Cardiology research and practice

    2019  Volume 2019, Page(s) 9156586

    Abstract: Background: Takotsubo syndrome (TTS) is characterized by acute transient, stress-induced, left ventricular systolic dysfunction, generally presenting with apical ballooning. It can mimic an acute coronary syndrome, but with a milder increase in cardiac ... ...

    Abstract Background: Takotsubo syndrome (TTS) is characterized by acute transient, stress-induced, left ventricular systolic dysfunction, generally presenting with apical ballooning. It can mimic an acute coronary syndrome, but with a milder increase in cardiac enzymes and without culprit coronary artery disease on angiography. Data on long-term follow-up and survival in patients with TTS, compared with patients with ST-elevation myocardial infarction (STEMI), are scarce.
    Purpose: To assess all-cause mortality rate and survival in a consecutive series of female patients with TTS compared with age- and sex-matched STEMI patients on long-term follow-up.
    Methods and results: We collected data of 65 TTS female patients (TTS group) with a mean age of 73.42 ± 11.35 years from 2001 to 2013. Collection of follow-up information was concluded for all patients in 2016. To compare the mortality and survival of TTS patients with those of the STEMI population, we used data from our STEMI Registry, a prospective registry of 7446 STEMI patients admitted from 2001 to 2013 to our cath-lab for primary percutaneous coronary intervention (p-PCI). From the registry, we selected 104 STEMI patients (STEMI group) comparable to our TTS group in terms of age (mean age of 72.33 ± 11.92 years) and sex. On follow-up examination after a median of 1000 days, the TTS group had a lower all-cause mortality rate than the STEMI group (7.69% versus 23.08%). This difference was statistically different between the two groups (log-rank test,
    Conclusions: In our study, TTS and STEMI patients displayed a statistically significant difference in long-term survival. Specifically, the TTS group had a lower mortality rate than the STEMI group. This seems to suggest that TTS and STEMI are two different clinical entities with two different clinical outcomes.
    Language English
    Publishing date 2019-07-30
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2506187-2
    ISSN 2090-0597 ; 2090-8016
    ISSN (online) 2090-0597
    ISSN 2090-8016
    DOI 10.1155/2019/9156586
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  3. Article: Modifications of minimal luminal diameter during the 24 hours following percutaneous treatment of in-stent restenosis.

    Rubartelli, Paolo / Giachero, Corinna / Abbadessa, Francesco / Vischi, Massimo / Chierchia, Sergio

    The Journal of invasive cardiology

    2004  Volume 16, Issue 10, Page(s) 575–577

    Abstract: The early renarrowing after percutaneous coronary interventions (PCI) for in-stent restenosis (ISR) is a phenomenon that has received little investigation. Therefore, we assessed the angiographic minimal luminal diameter (MLD) before, immediately after, ... ...

    Abstract The early renarrowing after percutaneous coronary interventions (PCI) for in-stent restenosis (ISR) is a phenomenon that has received little investigation. Therefore, we assessed the angiographic minimal luminal diameter (MLD) before, immediately after, and 24 hours after the procedure in 30 ISR's treated with balloon angioplasty (BA) or rotational atherectomy (RA). The MLD was 0.68+/-0.48 mm at baseline, 2.42+/-0.38 mm after the procedure, and 2.25+/-0.39 mm at 24 hours (p < 0.0001 for all comparisons). Therefore, a small but significant decrease in MLD between post-procedure and 24 hours, corresponding to an early loss of 0.18+/-0.16 mm, was evident. The early loss was not significantly different in ISR's treated with BA or RA (0.15+/-0.16 mm and 0.20+/-0.16 mm, respectively). No significant correlation between early loss and lesion length, diameter stenosis, reference diameter, and acute gain was found. However, no increase of the 24-hour diameter stenosis to more than 50% was observed. We conclude that the magnitude of early luminal loss after PCI of ISR is small and therefore does not generally constitute a clinical problem.
    MeSH term(s) Aged ; Angioplasty, Balloon, Coronary/adverse effects ; Atherectomy/adverse effects ; Blood Vessel Prosthesis Implantation/adverse effects ; Body Weights and Measures ; Coronary Angiography ; Coronary Restenosis/diagnostic imaging ; Coronary Stenosis/therapy ; Female ; Humans ; Male ; Middle Aged ; Stents/adverse effects ; Time Factors
    Language English
    Publishing date 2004-10
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1154372-3
    ISSN 1042-3931
    ISSN 1042-3931
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    Zs.A 3701: Show issues Location:
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    Zs.MO 272: Show issues
    Zs.MG 31: Show issues

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  4. Article: Long-term follow-up of Tako-Tsubo-like syndrome: a retrospective study of 22 cases.

    Valbusa, Alberto / Abbadessa, Francesco / Giachero, Corinna / Vischi, Massimo / Zingarelli, Antonio / Olivieri, Roberto / Visconti, Luigi Oltrona

    Journal of cardiovascular medicine (Hagerstown, Md.)

    2008  Volume 9, Issue 8, Page(s) 805–809

    Abstract: Objectives: To assess the late outcome of the Tako-Tsubo like syndrome in a community hospital in northern Italy.: Methods and results: We reviewed 2233 patients who were admitted from 2001 to 2006 with diagnosis of acute coronary syndrome. Twenty- ... ...

    Abstract Objectives: To assess the late outcome of the Tako-Tsubo like syndrome in a community hospital in northern Italy.
    Methods and results: We reviewed 2233 patients who were admitted from 2001 to 2006 with diagnosis of acute coronary syndrome. Twenty-two patients (1%) presenting clinical and instrumental characteristics of Tako-Tsubo like syndrome were included in the study and prospectively underwent clinical and echocardiographic follow-up. All patients were women; aged 76 +/- 7 years; 82% experienced a stress before the acute episode; 50% reported chest pain and dyspnoea also days before. Mean troponin peak value was 3.6 +/- 3.3 microg/l. Mean acute echocardiographic ejection fraction was 40 +/- 7%. Eighteen percent of them presented major in-hospital complications. At a mean follow-up time of 27 +/- 19 months, 2 patients (9%) died because of ischemic stroke and renal failure, respectively, 14 (63%) were asymptomatic, 1 (5%) declared a paroxysmal episode of atrial fibrillation, and 5 (23%) still lamented dyspnoea or atypical chest pain. In all patients, typical apical ballooning disappeared and an increase in mean ejection fraction to 60 +/- 4% was observed.
    Conclusion: After complications are promptly recognized and treated in the acute phase, prognosis of Tako-Tsubo like syndrome appears to be good at long-term follow-up, with a complete recovery of normal left ventricular function.
    MeSH term(s) Aged ; Echocardiography/methods ; Electrocardiography ; Female ; Follow-Up Studies ; Humans ; Male ; Prognosis ; Prospective Studies ; Severity of Illness Index ; Stroke Volume/physiology ; Takotsubo Cardiomyopathy/diagnostic imaging ; Takotsubo Cardiomyopathy/physiopathology ; Time Factors ; Ventricular Function, Left/physiology
    Language English
    Publishing date 2008-08
    Publishing country United States
    Document type Comparative Study ; Journal Article
    ZDB-ID 2223461-5
    ISSN 1558-2035 ; 1558-2027
    ISSN (online) 1558-2035
    ISSN 1558-2027
    DOI 10.2459/JCM.0b013e3282f73264
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.MO 559: Show issues

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  5. Article: Transcranial Doppler monitoring during stenting of the carotid bifurcation: evaluation of two different distal protection devices in preventing embolization.

    Rubartelli, Paolo / Brusa, Giulia / Arrigo, Alessandro / Abbadessa, Francesco / Giachero, Corinna / Vischi, Massimo / Ricca, Maria Maddalena / Ottonello, Gian Andrea

    Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists

    2006  Volume 13, Issue 4, Page(s) 436–442

    Abstract: Purpose: To compare the efficacy of 2 emboli protection devices in preventing embolization during carotid artery stenting (CAS).: Methods: The GuardWire distal occlusion system (n=19) and the distal FilterWire EX (n=12) were compared in 31 ... ...

    Abstract Purpose: To compare the efficacy of 2 emboli protection devices in preventing embolization during carotid artery stenting (CAS).
    Methods: The GuardWire distal occlusion system (n=19) and the distal FilterWire EX (n=12) were compared in 31 consecutive patients (24 men; mean age 71+/-10 years) monitored with transcranial Doppler for microembolic signals before, during, and after CAS. The choice of the protection device was based on availability and on the patency of the contralateral carotid artery.
    Results: The baseline characteristics were similar in the patients treated under protection from either device. Placement and retrieval of the protection device, stenting, and postdilation were technically successful in all patients. Two patients suffered a transient ischemic attack shortly after the procedure; no other adverse cardiovascular events occurred at 30 days. Compared to the GuardWire, the use of the FilterWire was associated with more microembolic signals during stent deployment (77.4+/-33.5 versus 1.07+/-1.94, p<0.0001), postdilation (63.9+/-21.0 versus 2.06+/-2.58, p<0.0001), and retrieval of the protection device (21.4+/-15.4 versus 10.9+/-8.3, p=0.051). Consequently, the total amount of microembolic signals during the procedure was higher when the filter device was employed (183.0+/-42.1 versus 31.7+/-12.0, p<0.0001).
    Conclusion: The distal occlusion device appears to be more effective than the filter in reducing distal embolization detected by transcranial Doppler monitoring.
    MeSH term(s) Aged ; Aged, 80 and over ; Angioplasty, Balloon ; Carotid Stenosis/diagnostic imaging ; Carotid Stenosis/therapy ; Cerebrovascular Circulation ; Female ; Humans ; Intracranial Embolism/prevention & control ; Ischemic Attack, Transient/prevention & control ; Male ; Middle Aged ; Monitoring, Physiologic/methods ; Stents ; Treatment Outcome ; Ultrasonography, Doppler, Transcranial
    Language English
    Publishing date 2006-08
    Publishing country United States
    Document type Clinical Trial ; Comparative Study ; Journal Article
    ZDB-ID 2006618-1
    ISSN 1545-1550 ; 1526-6028
    ISSN (online) 1545-1550
    ISSN 1526-6028
    DOI 10.1583/05-1804MR.1
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    Zs.A 4547: Show issues Location:
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  6. Article: Circumferential dissection of the ascending aorta with intimal intussusception. Case report and review of the literature.

    Lijoi, A / Scarano, F / Canale, C / Parodi, E / Dottori, V / Passerone, G C / Abbadessa, F / Piccardo, A

    Texas Heart Institute journal

    1994  Volume 21, Issue 2, Page(s) 166–169

    Abstract: The present report describes an unusual case (apparently the 10th in the world literature) of a type-A aortic dissection with full circumferential detachment of the ascending aortic intima and intussusception thereof into the aortic arch and descending ... ...

    Abstract The present report describes an unusual case (apparently the 10th in the world literature) of a type-A aortic dissection with full circumferential detachment of the ascending aortic intima and intussusception thereof into the aortic arch and descending aorta, partly occluding the arch vessels. Computed tomographic scanning and 2-dimensional echocardiography failed to detect an intimal flap and a false lumen in the ascending aorta. Aortic dissection was visualized by aortography. The ascending aorta was surgically repaired and the aortic valve resuspended. The pertinent literature is reviewed.
    MeSH term(s) Adult ; Aneurysm, Dissecting/epidemiology ; Aneurysm, Dissecting/pathology ; Aorta/pathology ; Aortic Aneurysm/epidemiology ; Aortic Aneurysm/pathology ; Humans ; Male ; Tunica Intima/pathology
    Language English
    Publishing date 1994
    Publishing country United States
    Document type Case Reports ; Journal Article ; Review
    ZDB-ID 604761-0
    ISSN 1526-6702 ; 0730-2347
    ISSN (online) 1526-6702
    ISSN 0730-2347
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  7. Article ; Online: Distal protection with a filter device during coronary stenting in patients with stable and unstable angina.

    Angelini, Annalisa / Rubartelli, Paolo / Mistrorigo, Flavio / Della Barbera, Mila / Abbadessa, Francesco / Vischi, Massimo / Thiene, Gaetano / Chierchia, Sergio

    Circulation

    2004  Volume 110, Issue 5, Page(s) 515–521

    Abstract: Background: Filter protection after percutaneous coronary intervention (PCI) is now available to prevent distal embolization. The aims of this study were (1) to evaluate the microembolization phenomenon during procedures of stent implantation in native ... ...

    Abstract Background: Filter protection after percutaneous coronary intervention (PCI) is now available to prevent distal embolization. The aims of this study were (1) to evaluate the microembolization phenomenon during procedures of stent implantation in native coronary arteries of patients with stable and unstable angina, (2) to assess the amount and characteristics of the debris captured by the Angioguard, and (3) to investigate the relation between clinical and angiographic variables and pathological data.
    Methods and results: Elective coronary stenting with the use of a protective filter was attempted in 39 consecutive coronary artery lesions with >60% stenosis (mean, 67.6+/-8.79%). Debris was present in 75.6% of the filters. Particle size ranged from 47.16 to 2503.48 microm (mean, 518.83+/-319.61 microm) in the major axis. Particles >300 microm were found in 24 of 28 filters with debris (85.7%), and particles >1000 microm were present in 10 of 28 filters (35.7%). Patients with unstable angina had greater particles (mean maximum longitudinal diameter, 1098.33+/-714.3 microm) than those with stable angina (412.91+/-453 microm; P<0.001). The presence of unstable angina (OR, 65; CI, 1.2 to 3420; P=0.03) and age >67 years (OR, 42; CI, 1 to 1698; P=0.04) were found to be the only independent predictors of embolic particle size.
    Conclusions: By limiting embolization, protective devices may prevent a number of potentially unfavorable events, thereby improving outcome. Our data support the use of these devices, especially in lesions with higher embolic potential, such as those occurring in older patients and in those with unstable angina.
    MeSH term(s) Aged ; Angina Pectoris/etiology ; Angina Pectoris/surgery ; Angina, Unstable/etiology ; Angina, Unstable/surgery ; Angioplasty, Balloon, Coronary/adverse effects ; Coronary Stenosis/complications ; Coronary Stenosis/pathology ; Coronary Stenosis/surgery ; Embolism/epidemiology ; Embolism/etiology ; Embolism/prevention & control ; Feasibility Studies ; Female ; Humans ; Intraoperative Complications/prevention & control ; Male ; Middle Aged ; Particle Size ; Platelet Aggregation Inhibitors/administration & dosage ; Platelet Aggregation Inhibitors/therapeutic use ; Premedication ; Prospective Studies ; Risk Factors ; Stents ; Treatment Outcome ; Vena Cava Filters
    Chemical Substances Platelet Aggregation Inhibitors
    Language English
    Publishing date 2004-08-03
    Publishing country United States
    Document type Clinical Trial ; Journal Article
    ZDB-ID 80099-5
    ISSN 1524-4539 ; 0009-7322 ; 0069-4193 ; 0065-8499
    ISSN (online) 1524-4539
    ISSN 0009-7322 ; 0069-4193 ; 0065-8499
    DOI 10.1161/01.CIR.0000137821.94074.EE
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    Ui IV Zs.60: Show issues Location:
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  8. Article: Valutazione della gravità della stenosi valvolare aortica: calcolo dell'area o gradiente al picco? Affidabilità della formula di Hakki.

    Mazzantini, S / Miccoli, F / Vischi, M / Rubartelli, P / Abbadessa, F / Della Rovere, F

    Giornale italiano di cardiologia

    1985  Volume 15, Issue 5, Page(s) 502–506

    Abstract: The severity of aortic valve stenosis should be assessed by means of the calculation of the valvular area; on the other hand, the routine use of the Gorlin's formula for the aortic area is laborious and time consuming. Recently Hakki proposed a ... ...

    Title translation Evaluation of the seriousness of aortic valve stenosis: calculation of the valvular area or peak? Reliability of Hakki's formula.
    Abstract The severity of aortic valve stenosis should be assessed by means of the calculation of the valvular area; on the other hand, the routine use of the Gorlin's formula for the aortic area is laborious and time consuming. Recently Hakki proposed a simplified formula (area = cardiac output/square root gradient) for the calculation of valvular areas. This method does not require the assessment of the systolic ejection time or the transvalvular flow; furthermore, the peak systolic gradient instead of the mean gradient may be entered into the formula. We have evaluated the reliability of this formula on 83 patients with aortic valve stenosis either pure or with absent to mild aortic incompetence (angiographically first degree maximum). Twenty-eight patients had isolated aortic stenosis, 55 had associated mitral stenosis and/or mitral or tricuspid regurgitation. Our results show a good correlation between the values of valvular areas obtained by Hakki's formula and those obtained by Gorlin's formula (r = 0.90 in the first group and r = 0.91 in the second group of patients). On the contrary we observed a poor relationship between the peak systolic gradient and the valvular area, with a considerable scatter of the data, especially for low values of peak systolic gradient. We therefore conclude that the assessment of the aortic valve stenosis must be based on the estimation of the valvular area; in our hands the Hakki's formula has proven to be easy and sufficiently reliable for routine diagnostic studies.
    MeSH term(s) Adolescent ; Adult ; Aged ; Angiography ; Aortic Valve Insufficiency/complications ; Aortic Valve Stenosis/complications ; Aortic Valve Stenosis/physiopathology ; Cardiac Output ; Female ; Humans ; Male ; Mathematics ; Middle Aged ; Mitral Valve Stenosis/complications ; Models, Cardiovascular ; Systole
    Language Italian
    Publishing date 1985-05
    Publishing country Italy
    Document type English Abstract ; Journal Article
    ZDB-ID 184670-x
    ISSN 0046-5968
    ISSN 0046-5968
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  9. Article: Corrispettivo anatomo-funzionale delle alterazioni della ripolarizzazione all'elettrocardiogramma nelle insufficienze valvolari aortica e mitralica. Confronto con gli indici basati sul voltaggio del QRS.

    Badano, L / Rubartelli, P / Della Rovere, F / Abbadessa, F / Miccoli, F / Vischi, M / Gatto, E

    Giornale italiano di cardiologia

    1989  Volume 19, Issue 6, Page(s) 483–490

    Abstract: Electrocardiographic repolarization changes and voltage criteria for left ventricular hypertrophy were examined, in relation to hemodynamic, echocardiographic and angiographic data. This was done to evaluate their association with abnormalities in ... ...

    Title translation Anatomo-functional correlations of changes in electrocardiographic repolarization in aortic and mitral valve insufficiency. Comparison of indices based on QRS voltages.
    Abstract Electrocardiographic repolarization changes and voltage criteria for left ventricular hypertrophy were examined, in relation to hemodynamic, echocardiographic and angiographic data. This was done to evaluate their association with abnormalities in cardiac function and structure in 53 patients with chronic aortic regurgitation and 36 patients with chronic mitral regurgitation. No patient showed evidence of coronary artery disease. Of the patients with aortic regurgitation, the 27 patients with an abnormal repolarization pattern at ECG had worse NYHA functional class when compared to the 24 patients with normal repolarization (2.4 +/- 1 vs 1.6 +/- 0.9; p less than .01). They also had greater left ventricular dimensions (end-diastolic volume: 162 +/- 57 ml/m2 vs 109 +/- 15 ml/m2, p less than .01; end-systolic volume: 85 +/- 46 ml/m2 vs 44 +/- 31 ml/m2, p less than .01), lower left ventricular ejection fraction (.50 +/- .12 vs .63 +/- .14; p less than .01), greater left ventricular mass (170 +/- 56 gr/m2 vs 119 +/- 29 gr/m2; p less than .01) and higher end-diastolic left ventricular pressure (21 +/- 11 mmHg vs 11 +/- 8 mmHg; p less than .01). QRS voltage was less closely related to cardiac function and structure and thus, did not modify the conclusions based on repolarization findings alone. Furthermore, repolarization patterns identified patient subgroups with high or low prevalences of previously described predictors of poor surgical outcome. The presence or absence of the "strain" pattern was not related to differences in cardiac structure and function, in patients with mitral regurgitation.(ABSTRACT TRUNCATED AT 250 WORDS)
    MeSH term(s) Adult ; Aged ; Aortic Valve Insufficiency/physiopathology ; Cardiomegaly/physiopathology ; Chronic Disease ; Electrocardiography ; Female ; Hemodynamics ; Humans ; Male ; Middle Aged ; Mitral Valve Insufficiency/physiopathology
    Language Italian
    Publishing date 1989-06
    Publishing country Italy
    Document type English Abstract ; Journal Article
    ZDB-ID 184670-x
    ISSN 0046-5968
    ISSN 0046-5968
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  10. Article: La rottura postinfartuale del setto interventricolare. Nostra esperienza ed attuali orientamenti.

    Dottori, V / Della Rovere, F / Secchi, G L / Badano, L / Abbadessa, F / Pergolo, A / Delfino, R / Ficara, S / Spagnolo, S

    Minerva cardioangiologica

    1988  Volume 36, Issue 6, Page(s) 265–269

    Title translation Post-infarction rupture of the interventricular septum. Our experience and current trends.
    MeSH term(s) Age Factors ; Aged ; Female ; Heart Rupture/etiology ; Heart Rupture/surgery ; Heart Rupture, Post-Infarction/etiology ; Heart Rupture, Post-Infarction/surgery ; Heart Septum ; Heart Ventricles ; Humans ; Male ; Middle Aged ; Risk Factors
    Language Italian
    Publishing date 1988-06
    Publishing country Italy
    Document type English Abstract ; Journal Article
    ZDB-ID 123583-7
    ISSN 1827-1618 ; 0026-4725
    ISSN (online) 1827-1618
    ISSN 0026-4725
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