Article: Identification of some variable parameters in serum of COVID-19 patients in comparison with control group.
The Egyptian journal of immunology
2024 Volume 31, Issue 2, Page(s) 10–17
Abstract: The study intended to determine the correlation among coronavirus disease 2019 (COVID-19) infection and variable abnormalities in liver function test, lipids, and thyroid hormones. The study included 160 infected COVID-19 patients (80 females and 80 male) ...
| Abstract | The study intended to determine the correlation among coronavirus disease 2019 (COVID-19) infection and variable abnormalities in liver function test, lipids, and thyroid hormones. The study included 160 infected COVID-19 patients (80 females and 80 male) and 100 subjects as a control group (50 females and 50 males), attended the Al-Sader Medical City in Al-Najaf, Iraq during the period between January 2021 to October 2021. The patients' age ranged from 16-80 years old. Liver enzymes, lipid profile and thyroid hormone were tested. The results revealed a significant increase in liver function levels including alanine transaminase, aspartate aminotransferase, alkaline phosphatase, and Albumin (p < 0.05). Also, there was an increase in lipids levels including total cholesterol, low-density lipoprotein, and triglycerides. The result showed significant difference in levels of thyroid hormones triiodothyronine, thyroxine and thyroid stimulating hormone between COVID-19 infected patients and the control group. As well the antithyroid antibodies (thyroglobulin antibody, thyroid peroxidase antibody and thyrotropin receptor antibodies) were increased. There was a correlation between increasing thyroid hormones and their antibodies with infection by COVID-19. This study concluded that COVID-19 infection can induce disturbances in liver and thyroid function tests and changes in the lipid metabolism. |
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| MeSH term(s) | Female ; Humans ; Male ; Adolescent ; Young Adult ; Adult ; Middle Aged ; Aged ; Aged, 80 and over ; Control Groups ; COVID-19 ; Liver ; Thyroid Hormones ; Lipids |
| Chemical Substances | Thyroid Hormones ; Lipids |
| Language | English |
| Publishing date | 2024-04-04 |
| Publishing country | Egypt |
| Document type | Journal Article |
| ISSN | 1110-4902 |
| ISSN | 1110-4902 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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