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  1. Book ; Online: Generation, Development and Modifications of Natural Fibers

    Abbas, Mudassar / Jeon, Han-Yong

    2020  

    Keywords Spectrum analysis, spectrochemistry, mass spectrometry ; Polymer chemistry
    Size 1 electronic resource (142 pages)
    Publisher IntechOpen
    Document type Book ; Online
    Note English ; Open Access
    HBZ-ID HT021045406
    ISBN 9781789856880 ; 1789856884
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Article ; Online: Advanced Techniques in Predicting Breast Tumor Response to Neoadjuvant Chemotherapy.

    Abbas, Mohamed

    Discovery medicine

    2021  Volume 31, Issue 163, Page(s) 69–77

    Abstract: Neoadjuvant therapy is used to treat breast cancer through preventive agents. This new type of chemotherapy is prescribed according to the size of the tumor, so as to reduce the tumor mass and give more surgical options. Neoadjuvant hormone treatment is ... ...

    Abstract Neoadjuvant therapy is used to treat breast cancer through preventive agents. This new type of chemotherapy is prescribed according to the size of the tumor, so as to reduce the tumor mass and give more surgical options. Neoadjuvant hormone treatment is also helping to shrink breast cancer in lymph nodes or elsewhere in the breast before surgery. A significant aspect of the treatment is to predict breast tumor response to neoadjuvant chemotherapy. Here, the latest advanced breast tumor response techniques have been presented for this type of therapy. These techniques are classified into three categories: deep and machine learning, quantitative ultrasound spectroscopy, and magnetic resonance imaging. These methods were important for the prediction of a tumor's chemical response to the neoadjuvant chemotherapy. Tumor response assessment leads to effective chemical treatment, which decreases the size of the breast tumor and allows surgery to remove the tumor effectively.
    MeSH term(s) Breast Neoplasms/drug therapy ; Chemotherapy, Adjuvant ; Female ; Humans ; Lymph Nodes/diagnostic imaging ; Magnetic Resonance Imaging ; Neoadjuvant Therapy ; Treatment Outcome ; Ultrasonography
    Language English
    Publishing date 2021-12-26
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2415544-5
    ISSN 1944-7930 ; 1944-7930
    ISSN (online) 1944-7930
    ISSN 1944-7930
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Potential Role of Nanoparticles in Treating the Accumulation of Amyloid-Beta Peptide in Alzheimer's Patients.

    Abbas, Mohamed

    Polymers

    2021  Volume 13, Issue 7

    Abstract: The disorder of Alzheimer's is marked by progressive pathophysiological neurodegeneration. The amino acid peptides in the amyloid plaques found in the brains of people with Alzheimer's disease (AD) are known as amyloid-beta (Aβ). Current treatments are ... ...

    Abstract The disorder of Alzheimer's is marked by progressive pathophysiological neurodegeneration. The amino acid peptides in the amyloid plaques found in the brains of people with Alzheimer's disease (AD) are known as amyloid-beta (Aβ). Current treatments are not curative, and the effects associated with AD are reduced. Improving treatment results involved the targeting of drugs at optimum therapeutic concentration. Nanotechnology is seen as an unconventional, modern technology that plays a key role in the treatment of Alzheimer's disease. Using nanoparticles, molecular detection, effective drug targeting, and their combination offer high sensitivity. The aim of this review is to shed light on the function and successful role of nanoparticles to resolve Aβ aggregation and thus to help cure Alzheimer's disease. The analysis divides these nanoparticles into three categories: polymer, lipid, and gold nanoparticles. A thorough comparison was then made between the nanoparticles, which are used according to their role, properties, and size in the procedure. The nanoparticles can prevent the accumulation of Aβ during the efficient delivery of the drug to the cells to treat Alzheimer's disease. Furthermore, this comparison demonstrated the ability of these nanoparticles to deal efficiently with Alzheimer's disease. The role of these nanoparticles varied from delivering the drug to brain cells to dealing with the disease-causing peptide.
    Language English
    Publishing date 2021-03-27
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2527146-5
    ISSN 2073-4360 ; 2073-4360
    ISSN (online) 2073-4360
    ISSN 2073-4360
    DOI 10.3390/polym13071051
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Is there a need for universal double reflex testing of HBsAg-positive individuals for hepatitis D infection?

    Abbas, Zaigham / Abbas, Minaam

    World journal of hepatology

    2024  Volume 16, Issue 3, Page(s) 300–303

    Abstract: Hepatitis D virus (HDV) can infect HBsAg-positive individuals, causing rapid fibrosis progression, early decompensation, increased hepatocellular carcinoma risk, and higher mortality than hepatitis B virus (HBV) mono-infection. Most countries lack high- ... ...

    Abstract Hepatitis D virus (HDV) can infect HBsAg-positive individuals, causing rapid fibrosis progression, early decompensation, increased hepatocellular carcinoma risk, and higher mortality than hepatitis B virus (HBV) mono-infection. Most countries lack high-quality HDV prevalence data, and the collection techniques employed often bias published data. In recent meta-analyses, HDV prevalence in HBsAg-positive patients reaches 5%-15% and is even significantly higher in endemic areas. Since HBV vaccination programs were implemented, HDV prevalence has decreased among younger populations. However, owing to immigrant influx, it has increased in some Western countries. The current practice of HDV screening in HBsAg-positive individuals is stepwise, based on physician's discretion, and limited to at-risk populations and may require numerous visits. Double reflex testing, which includes anti-HDV testing in all HBsAg-positive individuals and then HDV RNA testing for anti-HDV-positive ones, is uncommon. Reflex testing can identify more HDV infection cases and link identified patients to further care and follow-up. Moreover, laboratory-based double reflex screening is less biased than physician-led testing. Therefore, healthcare providers should learn about reflex testing, and federal and provincial hepatitis control programs should implement laboratory-based double reflex testing to obtain reliable HDV prevalence estimates. The test's cost-effectiveness depends on the number of HBV-positive patients screened to identify one HDV-positive patient. Such testing may be viable in areas with low HBsAg but high HDV prevalence. However, its economic impact on areas with low HDV prevalence needs further study.
    Language English
    Publishing date 2024-04-04
    Publishing country United States
    Document type Editorial
    ZDB-ID 2573703-X
    ISSN 1948-5182
    ISSN 1948-5182
    DOI 10.4254/wjh.v16.i3.300
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: A difficult diagnosis of eosinophilic fasciitis: A case report.

    Mihailescu, Mara / Abbas, Mariam

    SAGE open medical case reports

    2024  Volume 12, Page(s) 2050313X241231384

    Abstract: Eosinophilic fasciitis can be a debilitating diagnosis and is often delayed given its similarities to other sclerotic conditions including morphea, such as bound-down indurated skin and inflammation and sclerotic thickening of tissue layers on ... ...

    Abstract Eosinophilic fasciitis can be a debilitating diagnosis and is often delayed given its similarities to other sclerotic conditions including morphea, such as bound-down indurated skin and inflammation and sclerotic thickening of tissue layers on histopathology. Delaying treatment can lead to joint contracture and residual hardness in skin which has both cosmetic and functional implications. Therefore, finding the definitive diagnosis and differentiating from other sclerotic diseases is important early in the disease course. We present a case of a 77-year-old female with a generalized rash on her back and extremities, and progressive symptoms of pain, joint contractures, and limited movement, which highlights the challenges in diagnosis and management given clinical and histological parallels between eosinophilic fasciitis and morphea.
    Language English
    Publishing date 2024-04-24
    Publishing country England
    Document type Case Reports
    ZDB-ID 2736953-5
    ISSN 2050-313X
    ISSN 2050-313X
    DOI 10.1177/2050313X241231384
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Binary and ternary complex formation and characterization of artemisinin with sulfobutyl ether β-cyclodextrin and oleic acid.

    Yousaf Shahzad, Muhammad / Abbas, Muhammad / Ansari, Muhammad Tayyab / Abbas, Mudassar

    Pakistan journal of pharmaceutical sciences

    2024  Volume 37, Issue 1, Page(s) 43–52

    Abstract: Drug-resistant malaria is a global risk to the modern world. Artremisinin (ART) is one of the drugs of choice against drug-resistant (malaria) which is practically insoluble in water. The objective of our study was to improve the solubility of ... ...

    Abstract Drug-resistant malaria is a global risk to the modern world. Artremisinin (ART) is one of the drugs of choice against drug-resistant (malaria) which is practically insoluble in water. The objective of our study was to improve the solubility of artemisinin (ART) via development of binary complexes of ART with sulfobutylether β-cyclodextrins (SBE7 β-CD), sulfobutylether β-cyclodextrins (SBE7 β-CD) and oleic acid (ternary complexes). These are prepared in various drugs to excipients ratios by physical mixing (PM) and solvent evaporation (SE) methods. Characterizations were achieved by powder X-ray diffraction (PXRD), scanning electron microscopy (SEM) and attenuated total reflectance Fourier Transform Infrared (ATR-FTIR) spectroscopy. The aqueous-solubility in binary complexes was 12-folds enhanced than ternary complexes. Dissolution of binary and ternary complexes of artemisinin in simulated gastric fluid (pH 1.6) was found highest and 35 times higher for ternary SECx. The crystallinity of artemisinin was decreased in physical mixtures (PMs) while SECx exhibited displaced angles. The attenuated-intensity of SECx showed least peak numbers with more displaced-angles. SEM images of PMs and SECx showed reduced particle size in binary and ternary systems as compared to pure drug-particles. ATR-FTIR spectra of binary and ternary complexes revealed bonding interactions among artemisinin, SBE7 β-CD and oleic acid.
    MeSH term(s) beta-Cyclodextrins/chemistry ; Artemisinins/chemistry ; Solubility ; Oleic Acid/chemistry ; Spectroscopy, Fourier Transform Infrared ; X-Ray Diffraction ; Microscopy, Electron, Scanning ; Antimalarials/chemistry ; Excipients/chemistry ; Drug Compounding
    Chemical Substances beta-Cyclodextrins ; Artemisinins ; Oleic Acid (2UMI9U37CP) ; SBE4-beta-cyclodextrin (2PP9364507) ; Antimalarials ; artemisinin (9RMU91N5K2) ; Excipients
    Language English
    Publishing date 2024-05-14
    Publishing country Pakistan
    Document type Journal Article
    ZDB-ID 885131-1
    ISSN 1011-601X
    ISSN 1011-601X
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6588: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  7. Article: After crisis: health, politics and reflections on the European refugee crisis.

    Abbas, Mustafa

    Medicine, conflict, and survival

    2020  Volume 35, Issue 4, Page(s) 295–312

    Abstract: The years 2014 and 2015 saw a dramatic rise in the number of migrants entering Europe via the Mediterranean. This rise was mostly accounted for by refugees fleeing the civil war in the Syrian Arab Republic. Since that time Europe has been gripped in a ... ...

    Abstract The years 2014 and 2015 saw a dramatic rise in the number of migrants entering Europe via the Mediterranean. This rise was mostly accounted for by refugees fleeing the civil war in the Syrian Arab Republic. Since that time Europe has been gripped in a political and humanitarian crisis as the incoming numbers overwhelmed individual state and collective European Union ability to respond effectively. In this article, I explore the European Migrant Crisis in geographical, political and humanitarian perspectives, describing and explaining the key events of the crisis. I then go on to a study of the major health issues arising from the crisis in terms of communicable and non-communicable disease, mental health, gender-related health and access to healthcare. Finally, I discuss the global dimensions of the refugee crisis and enter into a discussion of the roles and effectiveness of the UNHCR and the European Union's response as a whole.
    MeSH term(s) Africa, Eastern/ethnology ; Africa, Western/ethnology ; Communicable Diseases/ethnology ; Europe ; Female ; Health Services Accessibility ; Health Status ; Humans ; Male ; Mental Health ; Middle East/ethnology ; Politics ; Refugees/psychology ; Refugees/statistics & numerical data ; Women's Health
    Keywords covid19
    Language English
    Publishing date 2020-02-04
    Publishing country England
    Document type Journal Article
    ZDB-ID 1314196-x
    ISSN 1362-3699
    ISSN 1362-3699
    DOI 10.1080/13623699.2020.1719581
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 2781: Show issues Location:
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  8. Article ; Online: Invited Commentary: Untangling the Web of Industry Payment, Publication Bias, and Cost Concerns in Acellular Dermal Matrix Use for Breast Reconstruction.

    Hassan, Abbas M / Butler, Charles E

    Journal of the American College of Surgeons

    2023  Volume 236, Issue 6, Page(s) 1197–1199

    MeSH term(s) Humans ; Female ; Acellular Dermis ; Publication Bias ; Mammaplasty ; Mastectomy ; Breast Neoplasms/surgery ; Breast Implantation ; Breast Implants ; Postoperative Complications ; Retrospective Studies
    Language English
    Publishing date 2023-03-20
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 1181115-8
    ISSN 1879-1190 ; 1072-7515
    ISSN (online) 1879-1190
    ISSN 1072-7515
    DOI 10.1097/XCS.0000000000000690
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Uk I Zs.61: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  9. Article ; Online: The stability analysis of a co-circulation model for COVID-19, dengue, and zika with nonlinear incidence rates and vaccination strategies.

    Omame, Andrew / Abbas, Mujahid

    Healthcare analytics (New York, N.Y.)

    2023  Volume 3, Page(s) 100151

    Abstract: This paper aims to study the impacts of COVID-19 and dengue vaccinations on the dynamics of zika transmission by developing a vaccination model with the incorporation of saturated incidence rates. Analyses are performed to assess the qualitative behavior ...

    Abstract This paper aims to study the impacts of COVID-19 and dengue vaccinations on the dynamics of zika transmission by developing a vaccination model with the incorporation of saturated incidence rates. Analyses are performed to assess the qualitative behavior of the model. Carrying out bifurcation analysis of the model, it was concluded that co-infection, super-infection and also re-infection with same or different disease could trigger backward bifurcation. Employing well-formulated Lyapunov functions, the model's equilibria are shown to be globally stable for a certain scenario. Moreover, global sensitivity analyses are performed out to assess the impact of dominant parameters that drive each disease's dynamics and its co-infection. Model fitting is performed on the actual data for the state of Amazonas in Brazil. The fittings reveal that our model behaves very well with the data. The significance of saturated incidence rates on the dynamics of three diseases is also highlighted. Based on the numerical investigation of the model, it was observed that increased vaccination efforts against COVID-19 and dengue could positively impact zika dynamics and the co-spread of triple infections.
    Language English
    Publishing date 2023-02-24
    Publishing country United States
    Document type Journal Article
    ISSN 2772-4425
    ISSN (online) 2772-4425
    DOI 10.1016/j.health.2023.100151
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: An Insight Into the Factors Affecting the Prevalence and Natural History of Hepatitis D.

    Abbas, Zaigham / Abbas, Minaam

    Cureus

    2023  Volume 15, Issue 8, Page(s) e43362

    Abstract: Epidemiological studies and recent metanalyses addressing hepatitis D have reported a wide variation in the prevalence of the disease. Between 4.5% to 15% of all hepatitis B surface antigen (HBsAg) positive patients are thought to harbor the hepatitis D ... ...

    Abstract Epidemiological studies and recent metanalyses addressing hepatitis D have reported a wide variation in the prevalence of the disease. Between 4.5% to 15% of all hepatitis B surface antigen (HBsAg) positive patients are thought to harbor the hepatitis D virus. The emergent variation in prevalence can be attributed to several factors. Unsurprisingly, published literature shows that the prevalence of the disease is higher in areas where aggregate viral hepatitis infections are endemic and amongst groups with high-risk practices facilitating the horizontal transfer. Meanwhile, the natural history of the disease is influenced by the genotype of the virus, the hepatitis D virus (HDV) RNA levels, HBV-HDV codominance, HBsAg titers, HBV genotype, nutritional status, HIV co-infection, and prior treatment. Together these factors contribute to the accelerated development of fibrosis and the increased risk of hepatocellular carcinoma. Superinfection with genotype 1 results in rapid progression to cirrhosis with lower rates of remission. Genotype 3 follows an aggressive course but shows a good response to interferon therapy. Other genotypes have better outcomes. The course of the disease leading to these outcomes can be tracked by HDV-specific models integrating clinical surrogate markers and epidemiological factors such as age, region, alanine aminotransferase (ALT), gamma-glutamyl transferase, albumin, platelets and cholinesterase, and liver stiffness.
    Language English
    Publishing date 2023-08-12
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.43362
    Database MEDical Literature Analysis and Retrieval System OnLINE

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